DE69421653D1 - Neue Anwendung von Alcaligenes faecalis Penicillin G Acylase - Google Patents

Neue Anwendung von Alcaligenes faecalis Penicillin G Acylase

Info

Publication number
DE69421653D1
DE69421653D1 DE69421653T DE69421653T DE69421653D1 DE 69421653 D1 DE69421653 D1 DE 69421653D1 DE 69421653 T DE69421653 T DE 69421653T DE 69421653 T DE69421653 T DE 69421653T DE 69421653 D1 DE69421653 D1 DE 69421653D1
Authority
DE
Germany
Prior art keywords
acylase
alcaligenes faecalis
new application
faecalis penicillin
penicillin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69421653T
Other languages
English (en)
Inventor
Vroom Erik De
Der Mey Margaretha Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke DSM NV
Original Assignee
DSM NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM NV filed Critical DSM NV
Application granted granted Critical
Publication of DE69421653D1 publication Critical patent/DE69421653D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/02—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C12P37/06—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by desacylation of the substituent in the 6 position

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
DE69421653T 1993-08-05 1994-08-05 Neue Anwendung von Alcaligenes faecalis Penicillin G Acylase Expired - Lifetime DE69421653D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP93202318 1993-08-05

Publications (1)

Publication Number Publication Date
DE69421653D1 true DE69421653D1 (de) 1999-12-23

Family

ID=8214032

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69421653T Expired - Lifetime DE69421653D1 (de) 1993-08-05 1994-08-05 Neue Anwendung von Alcaligenes faecalis Penicillin G Acylase

Country Status (5)

Country Link
EP (1) EP0638649B1 (de)
AT (1) ATE186746T1 (de)
DE (1) DE69421653D1 (de)
ES (1) ES2141796T3 (de)
PT (1) PT638649E (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002316991A (ja) * 2001-04-18 2002-10-31 Otsuka Chem Co Ltd ペニシリン及びセファロスポリン化合物
CZ300467B6 (cs) 2007-01-31 2009-05-27 Mikrobiologický ústav AV CR, v.v.i. Sekvence nukleotidu o velikosti 2646 bp, kódující penicilinacylázu, nové konstrukty rekombinantní nukleové kyseliny a rekombinantní mikroorganismy nesoucí tuto sekvenci
CN101245328B (zh) * 2008-03-21 2010-06-16 湘潭大学 一种粪产碱杆菌及其用于催化降解苯酚废水的方法
CN104045655B (zh) * 2014-06-23 2016-08-17 山东普洛得邦医药有限公司 一种抗菌素头孢母核的合成方法
CN107858312B (zh) * 2017-12-07 2020-11-17 北京理工大学 一株β-内酰胺类抗生素降解菌株PGB1及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3239427A (en) * 1959-10-12 1966-03-08 Pfizer & Co C Production of 6-aminopenicillanic acid
GB957685A (en) * 1961-07-27 1964-05-13 Ici Ltd Production of 6-aminopenicillanic acid
GB957449A (en) * 1961-08-10 1964-05-06 Ici Ltd Fermentative production of bacterial cells containing penicillinamidases
US3272715A (en) * 1962-07-17 1966-09-13 American Home Prod Method for producing and recovering 6-aminopenicillanic acid
GB1217143A (en) * 1967-02-13 1970-12-31 Beecham Group Ltd Penicillins
KR100193802B1 (ko) * 1990-04-18 1999-06-15 한스 월터 라벤 돌연변이된 베타-락탐 아실라아제 유전자
DE69110952T2 (de) * 1990-04-18 1995-11-16 Gist Brocades Nv Penicillin-G-Acylase, dafür kodierendes Gen und Verfahren zur Herstellung von diesem Enzym.

Also Published As

Publication number Publication date
EP0638649A2 (de) 1995-02-15
ATE186746T1 (de) 1999-12-15
EP0638649A3 (de) 1995-03-15
EP0638649B1 (de) 1999-11-17
ES2141796T3 (es) 2000-04-01
PT638649E (pt) 2000-04-28

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Legal Events

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8332 No legal effect for de