DE69319683D1 - Verfahren zur Herstellung von Thienothiopyran-Derivaten - Google Patents
Verfahren zur Herstellung von Thienothiopyran-DerivatenInfo
- Publication number
- DE69319683D1 DE69319683D1 DE69319683T DE69319683T DE69319683D1 DE 69319683 D1 DE69319683 D1 DE 69319683D1 DE 69319683 T DE69319683 T DE 69319683T DE 69319683 T DE69319683 T DE 69319683T DE 69319683 D1 DE69319683 D1 DE 69319683D1
- Authority
- DE
- Germany
- Prior art keywords
- thienothiopyran
- derivatives
- preparation
- thienothiopyran derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/185—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP25782292A JP3279671B2 (ja) | 1992-09-28 | 1992-09-28 | チエノチオピラン誘導体の製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69319683D1 true DE69319683D1 (de) | 1998-08-20 |
DE69319683T2 DE69319683T2 (de) | 1999-03-18 |
Family
ID=17311609
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69319683T Expired - Lifetime DE69319683T2 (de) | 1992-09-28 | 1993-09-25 | Verfahren zur Herstellung von Thienothiopyran-Derivaten |
Country Status (4)
Country | Link |
---|---|
US (1) | US5565345A (de) |
EP (1) | EP0590549B1 (de) |
JP (1) | JP3279671B2 (de) |
DE (1) | DE69319683T2 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5474919A (en) * | 1994-09-13 | 1995-12-12 | Merck & Co., Inc. | Bioconversion process for the synthesis of transhydroxy sulfone by Rhodotorula rubra or Rhodotorula piliminae |
ES2177415B1 (es) | 2000-09-04 | 2004-10-16 | Ragactives, S.L. | Procedimiento para la obtencion de 4-alquilamino-5, 6-dihidro-4h-tieno-(2,3b)-tiopiran-2-sulfonamida-7-dioxidos, e intermedios. |
CN101735209B (zh) * | 2008-11-12 | 2012-01-11 | 上海百灵医药科技有限公司 | 手性杜塞酰胺盐酸盐的合成方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4863922A (en) * | 1984-12-12 | 1989-09-05 | Merck & Co., Inc. | Substituted aromatic sulfonamides as antiglaucoma agents, compositions and use |
US4857468A (en) * | 1985-04-13 | 1989-08-15 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Process for preparing optically active 2-halo-1-phenyl ethanol |
DE3638759A1 (de) * | 1986-11-13 | 1988-06-09 | Schering Ag | Stereospezifische ketoreduktion von bicyclooctandion-carbonsaeureestern durch mikroorganismen |
US4968815A (en) * | 1990-04-16 | 1990-11-06 | Merck & Co., Inc. | Synthesis of (S)-3-(thien-2-ylthio)butyric acid analogs |
US5039802A (en) * | 1990-04-18 | 1991-08-13 | Merck & Co., Inc. | Arylation process for preparation of chiral catalysts for ketone reduction |
US5157129A (en) * | 1990-04-18 | 1992-10-20 | Merck & Co., Inc. | Enantiospecific synthesis of s-(+)-5,6-dihydro-4-(r-amino)-4h-thieno(2,3-b)thiopyran-2-sulfonamide-7,7-dioxide |
DE69131685T2 (de) * | 1990-07-24 | 2000-04-27 | Kanegafuchi Kagaku Kogyo K.K., Osaka | Verfahren zur herstellung optisch aktiven (-)-2-halo-1-(substituiertes phenyl)ethanols |
ES2093980T3 (es) * | 1992-08-28 | 1997-01-01 | Zeneca Ltd | Proceso de reduccion asimetrica, enzimatica, para producir derivados de 4h-tieno(2,3-6)tiopirano. |
-
1992
- 1992-09-28 JP JP25782292A patent/JP3279671B2/ja not_active Expired - Lifetime
-
1993
- 1993-09-25 EP EP93115506A patent/EP0590549B1/de not_active Expired - Lifetime
- 1993-09-25 DE DE69319683T patent/DE69319683T2/de not_active Expired - Lifetime
-
1995
- 1995-01-30 US US08/380,334 patent/US5565345A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP3279671B2 (ja) | 2002-04-30 |
US5565345A (en) | 1996-10-15 |
EP0590549A1 (de) | 1994-04-06 |
JPH06107667A (ja) | 1994-04-19 |
DE69319683T2 (de) | 1999-03-18 |
EP0590549B1 (de) | 1998-07-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |