DE69316572D1 - Messung von blutplättchenaktivitäten - Google Patents

Messung von blutplättchenaktivitäten

Info

Publication number
DE69316572D1
DE69316572D1 DE69316572T DE69316572T DE69316572D1 DE 69316572 D1 DE69316572 D1 DE 69316572D1 DE 69316572 T DE69316572 T DE 69316572T DE 69316572 T DE69316572 T DE 69316572T DE 69316572 D1 DE69316572 D1 DE 69316572D1
Authority
DE
Germany
Prior art keywords
platelets
measuring blood
methods
blood plate
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69316572T
Other languages
English (en)
Other versions
DE69316572T2 (de
Inventor
Hendrik Hemker
Robert Wagenvoord
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Switzerland
Original Assignee
Dade Producktions AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade Producktions AG filed Critical Dade Producktions AG
Publication of DE69316572D1 publication Critical patent/DE69316572D1/de
Application granted granted Critical
Publication of DE69316572T2 publication Critical patent/DE69316572T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96444—Factor X (3.4.21.6)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/04—Phospholipids, i.e. phosphoglycerides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69316572T 1992-06-03 1993-06-03 Messung von blutplättchenaktivitäten Expired - Lifetime DE69316572T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/892,865 US5266462A (en) 1992-06-03 1992-06-03 Measurement of platelet activities
PCT/US1993/005436 WO1993024840A1 (en) 1992-06-03 1993-06-03 Measurement of platelet activities

Publications (2)

Publication Number Publication Date
DE69316572D1 true DE69316572D1 (de) 1998-02-26
DE69316572T2 DE69316572T2 (de) 1998-09-10

Family

ID=25400634

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69316572T Expired - Lifetime DE69316572T2 (de) 1992-06-03 1993-06-03 Messung von blutplättchenaktivitäten

Country Status (9)

Country Link
US (1) US5266462A (de)
EP (1) EP0605674B1 (de)
JP (1) JP3143694B2 (de)
AT (1) ATE162632T1 (de)
AU (1) AU658073B2 (de)
CA (1) CA2114719C (de)
DE (1) DE69316572T2 (de)
ES (1) ES2114053T3 (de)
WO (1) WO1993024840A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9306053D0 (en) * 1993-03-24 1993-05-12 Nycomed Pharma As Method and assay
DE69513027T2 (de) * 1994-07-23 2000-03-16 Roche Diagnostics Gmbh Verfahren zur bestimmung des präthrombotischen status
US5763199A (en) * 1994-09-29 1998-06-09 Mount Sinai School Of Medicine Of The City University Of New York Platelet blockade assay
DE29723808U1 (de) * 1996-04-30 1999-11-04 Medtronic, Inc., Minneapolis, Minn. Vorrichtung zur Bestimmung der Blutplättcheninhibitor-Ansprechempfindlichkeit
US6221672B1 (en) 1996-04-30 2001-04-24 Medtronic, Inc. Method for determining platelet inhibitor response
US5951951A (en) 1997-04-30 1999-09-14 Medtronic, Inc. Platelet function evaluation technique for citrated whole blood
US6010911A (en) * 1997-04-30 2000-01-04 Medtronic, Inc. Apparatus for performing a heparin-independent high sensitivity platelet function evaluation technique
AU8388098A (en) * 1997-07-11 1999-02-08 Mount Sinai School Of Medicine Of The City University Of New York, The Assays for diagnosis of thrombophilic disease
US20040219682A1 (en) * 1997-09-18 2004-11-04 Ridgway Helen Jane Single-tube method and system for platelet function analysis
US6410337B1 (en) * 1997-09-18 2002-06-25 Helena Laboratories Corporation Method of platlet function analysis using platelet count
US20040219681A1 (en) * 1997-09-18 2004-11-04 Ridgway Helen Jane Two-tube method and system for platelet function analysis using platelet count
JP2002506038A (ja) * 1998-03-10 2002-02-26 バクスター・インターナショナル・インコーポレイテッド トロンビン調製およびトロンビン産物ならびにそれを使用するフィブリンシーラント方法
AU2431800A (en) * 1999-12-15 2001-06-25 Pentapharm Ag Hematological assay and reagent
WO2004024026A2 (en) 2002-09-10 2004-03-25 Ericson Daniel G Method and device for monitoring platelet function
ES2378544T3 (es) * 2003-07-08 2012-04-13 Accumetrics, Inc. Activación selectiva de plaquetas para el seguimiento de terapia con antagonistas de ADP
US20070243632A1 (en) * 2003-07-08 2007-10-18 Coller Barry S Methods for measuring platelet reactivity of patients that have received drug eluting stents
US7439069B2 (en) 2004-02-27 2008-10-21 Nippoldt Douglas D Blood coagulation test cartridge, system, and method
US7422905B2 (en) 2004-02-27 2008-09-09 Medtronic, Inc. Blood coagulation test cartridge, system, and method
US7399637B2 (en) 2004-04-19 2008-07-15 Medtronic, Inc. Blood coagulation test cartridge, system, and method
WO2005111231A2 (en) * 2004-05-11 2005-11-24 Heptest Laboratories, Inc. Compositions, kit and one-step method for monitoring compounds having anti-factor xa and/or anti factor iia activities
ATE532058T1 (de) 2004-05-17 2011-11-15 Medtronic Inc Point-of-care-heparinbestimmungssystem
EP1875232A2 (de) * 2005-04-25 2008-01-09 PlaCor, Inc. Verfahren und vorrichtungen zur überwachung der blutplättchenfunktion
US20100099130A1 (en) * 2006-10-25 2010-04-22 Placor Inc. Methods and devices for monitoring platelet function

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900679A (en) * 1983-01-26 1990-02-13 University Of Medicine And Dentistry Of New Jersey Method for determining the existence and/or the monitoring of a pathological condition in a mammal and a test kit therefor
US4728660A (en) * 1984-06-11 1988-03-01 University Of Miami Method of treating diseases arising from platelet hyperactivation
US5066788A (en) * 1984-09-21 1991-11-19 Boehringer Ingelheim International Gmbh Blood coagulation inhibiting proteins, processes for preparing them and their uses
KR930007434B1 (ko) * 1984-09-21 1993-08-10 베링거 잉겔하임 인터내셔날 게엠베하 혈액응고 억제 단백질 제조방법
US4871677A (en) * 1985-02-25 1989-10-03 Hemotec, Inc. Method of collecting and analyzing a sample of blood when monitoring heparin therapy
US5017556A (en) * 1986-11-04 1991-05-21 Genentech, Inc. Treatment of bleeding disorders using lipid-free tissue factor protein
US4880788A (en) * 1987-10-30 1989-11-14 Baylor College Of Medicine Method for preventing and treating thrombosis
US5120537A (en) * 1989-06-14 1992-06-09 Oklahoma Medical Research Foundation Factor xa based anticoagulant compositions

Also Published As

Publication number Publication date
ES2114053T3 (es) 1998-05-16
CA2114719A1 (en) 1993-12-09
WO1993024840A1 (en) 1993-12-09
DE69316572T2 (de) 1998-09-10
AU658073B2 (en) 1995-03-30
JPH06509479A (ja) 1994-10-27
AU4409093A (en) 1993-12-30
EP0605674A1 (de) 1994-07-13
EP0605674B1 (de) 1998-01-21
ATE162632T1 (de) 1998-02-15
US5266462A (en) 1993-11-30
CA2114719C (en) 1997-08-26
JP3143694B2 (ja) 2001-03-07

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