DE69217945D1 - azanorbornane derivatives - Google Patents

azanorbornane derivatives

Info

Publication number
DE69217945D1
DE69217945D1 DE1992617945 DE69217945A DE69217945D1 DE 69217945 D1 DE69217945 D1 DE 69217945D1 DE 1992617945 DE1992617945 DE 1992617945 DE 69217945 A DE69217945 A DE 69217945A DE 69217945 D1 DE69217945 D1 DE 69217945D1
Authority
DE
Germany
Prior art keywords
azanorbornane derivatives
azanorbornane
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE1992617945
Other languages
German (de)
Other versions
DE69217945T2 (en
Inventor
Brian O'neill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US71988491A priority Critical
Application filed by Pfizer Inc filed Critical Pfizer Inc
Priority to PCT/US1992/004697 priority patent/WO1993000330A2/en
Application granted granted Critical
Publication of DE69217945D1 publication Critical patent/DE69217945D1/en
Anticipated expiration legal-status Critical
Application status is Expired - Fee Related legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/14Nitrogen atoms not forming part of a nitro radical
DE1992617945 1991-06-21 1992-06-11 azanorbornane derivatives Expired - Fee Related DE69217945D1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US71988491A true 1991-06-21 1991-06-21
PCT/US1992/004697 WO1993000330A2 (en) 1991-06-21 1992-06-11 Azanorbornane derivatives

Publications (1)

Publication Number Publication Date
DE69217945D1 true DE69217945D1 (en) 1997-04-10

Family

ID=24891766

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1992617945 Expired - Lifetime DE69217945T2 (en) 1991-06-21 1992-06-11 azanorbornane derivatives
DE1992617945 Expired - Fee Related DE69217945D1 (en) 1991-06-21 1992-06-11 azanorbornane derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE1992617945 Expired - Lifetime DE69217945T2 (en) 1991-06-21 1992-06-11 azanorbornane derivatives

Country Status (18)

Country Link
US (1) US5604252A (en)
EP (1) EP0591333B1 (en)
KR (1) KR940701384A (en)
AT (1) AT149497T (en)
AU (1) AU2188992A (en)
CA (1) CA2111335A1 (en)
DE (2) DE69217945T2 (en)
DK (1) DK0591333T3 (en)
FI (1) FI935726A (en)
HU (1) HUT68957A (en)
IE (1) IE921987A1 (en)
IL (1) IL102208D0 (en)
MX (1) MX9203053A (en)
NO (1) NO934727L (en)
PT (1) PT100607A (en)
TW (1) TW202432B (en)
WO (1) WO1993000330A2 (en)
ZA (1) ZA9204527B (en)

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EP0659409A3 (en) * 1993-11-23 1995-08-09 Pfizer Substance 1 antagonists for the inhibition of angiogenesis.
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US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US5922737A (en) * 1996-02-21 1999-07-13 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5998439A (en) * 1996-02-21 1999-12-07 Hoescht Marion Roussel, Inc. Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
JP2001172178A (en) * 1999-10-25 2001-06-26 Pfizer Prod Inc Nk-1 receptor antagonist and eletriptan for treating megrim
US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
JP4907818B2 (en) 1999-11-03 2012-04-04 エーエムアール テクノロジー インコーポレイテッド Aryl and heteroaryl substituted tetrahydroisoquinolines and their use to prevent reuptake of norepinephrine, dopamine and serotonin
US7119207B2 (en) * 2000-04-10 2006-10-10 Pfizer Inc Benzoamide piperidine containing compounds and related compounds
MXPA02010029A (en) * 2000-04-10 2003-02-12 Pfizer Prod Inc Benzoamide piperidine compounds as substance p antagonists.
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KR101594898B1 (en) 2005-07-15 2016-02-18 알바니 몰레큘라 리써치, 인크. Aryl-and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
KR20080048502A (en) 2005-09-29 2008-06-02 머크 앤드 캄파니 인코포레이티드 Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
GB0603041D0 (en) 2006-02-15 2006-03-29 Angeletti P Ist Richerche Bio Therapeutic compounds
CA2664113C (en) 2006-09-22 2013-05-28 Merck & Co., Inc. Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer
PL2805945T3 (en) 2007-01-10 2019-09-30 Msd Italia S.R.L. Amide substituted indazoles as poly(ADP-ribose)polymerase (PARP) inhibitors
AU2008233662B2 (en) 2007-04-02 2012-08-23 Msd K.K. Indoledione derivative
EP2170076B1 (en) 2007-06-27 2016-05-18 Merck Sharp & Dohme Corp. 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
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US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
WO2010000073A1 (en) 2008-07-03 2010-01-07 Neuraxon, Inc. Benzoxazines, benzothiazines, and related compounds having nos inhibitory activity
US8691825B2 (en) 2009-04-01 2014-04-08 Merck Sharp & Dohme Corp. Inhibitors of AKT activity
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Family Cites Families (6)

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GB8823605D0 (en) * 1988-10-07 1988-11-16 Merck Sharp & Dohme Therapeutic agents
WO1990005525A1 (en) * 1988-11-23 1990-05-31 Pfizer Inc. Quinuclidine derivatives as substance p antagonists
WO1991009844A1 (en) * 1990-01-04 1991-07-11 Pfizer Inc. Substance p antagonists
KR937000499A (en) * 1990-06-01 1993-03-15 알렌 제이. 스피겔 3-amino-2-aryl quinuclidine, pharmaceutical compositions containing and methods of producing him
ES2065691T3 (en) * 1990-07-23 1995-02-16 Pfizer Quinuclidine derivatives.
DE69109125D1 (en) * 1990-09-28 1995-05-24 Pfizer Ring Linked analog heterocycles of nitrogen-containing non-aromatic.

Also Published As

Publication number Publication date
HU9303666D0 (en) 1994-04-28
EP0591333B1 (en) 1997-03-05
MX9203053A (en) 1992-12-01
IL102208D0 (en) 1993-01-14
FI935726D0 (en)
FI935726A0 (en) 1993-12-20
AU2188992A (en) 1993-01-25
EP0591333A1 (en) 1994-04-13
IE921987A1 (en) 1992-12-30
PT100607A (en) 1993-08-31
KR940701384A (en) 1994-05-28
NO934727D0 (en) 1993-12-20
CA2111335A1 (en) 1993-01-07
DK591333T3 (en)
WO1993000330A2 (en) 1993-01-07
HUT68957A (en) 1995-08-28
DE69217945T2 (en) 1997-06-12
US5604252A (en) 1997-02-18
WO1993000330A3 (en) 1993-03-04
ZA9204527B (en) 1993-12-20
NO934727L (en) 1993-12-20
DK0591333T3 (en) 1997-05-20
FI935726A (en) 1993-12-20
TW202432B (en) 1993-03-21
AT149497T (en) 1997-03-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee