DE69034168D1 - Expression von exogenen Polynukleotidsequenzen in Wirbeltieren - Google Patents

Expression von exogenen Polynukleotidsequenzen in Wirbeltieren

Info

Publication number
DE69034168D1
DE69034168D1 DE69034168A DE69034168A DE69034168D1 DE 69034168 D1 DE69034168 D1 DE 69034168D1 DE 69034168 A DE69034168 A DE 69034168A DE 69034168 A DE69034168 A DE 69034168A DE 69034168 D1 DE69034168 D1 DE 69034168D1
Authority
DE
Germany
Prior art keywords
vertebrates
expression
polynucleotide sequences
exogenous polynucleotide
exogenous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69034168A
Other languages
English (en)
Other versions
DE69034168T2 (de
DE69034168T3 (de
Inventor
Philip L Felgner
Jon Asher Wolff
Gary H Rhodes
Robert Wallace Malone
Dennis A Carson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vical Inc
Wisconsin Alumni Research Foundation
Original Assignee
Vical Inc
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to US32630589A priority Critical
Priority to US46788190A priority
Application filed by Vical Inc, Wisconsin Alumni Research Foundation filed Critical Vical Inc
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26985344&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69034168(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application granted granted Critical
Publication of DE69034168D1 publication Critical patent/DE69034168D1/de
Anticipated expiration legal-status Critical
Application status is Expired - Lifetime legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormones [GH] (Somatotropin)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0069Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12N9/1033Chloramphenicol O-acetyltransferase (2.3.1.28)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • C12N9/1247DNA-directed RNA polymerase (2.7.7.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y113/00Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13)
    • C12Y113/12Oxidoreductases acting on single donors with incorporation of molecular oxygen (oxygenases) (1.13) with incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)(1.13.12)
    • C12Y113/12007Photinus-luciferin 4-monooxygenase (ATP-hydrolysing) (1.13.12.7), i.e. firefly-luciferase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse Transcribing RNA Viruses
    • C12N2740/00011Reverse Transcribing RNA Viruses
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
DE69034168A 1989-03-21 1990-03-21 Expression von exogenen Polynukleotidsequenzen in Wirbeltieren Expired - Lifetime DE69034168D1 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US32630589A true 1989-03-21 1989-03-21
US46788190A true 1990-01-19 1990-01-19

Publications (1)

Publication Number Publication Date
DE69034168D1 true DE69034168D1 (de) 2004-10-28

Family

ID=26985344

Family Applications (6)

Application Number Title Priority Date Filing Date
DE69032284A Revoked DE69032284D1 (de) 1989-03-21 1990-03-21 Expression von exogenen polynukleotidsequenzen in wirbeltieren
DE69034168A Expired - Lifetime DE69034168D1 (de) 1989-03-21 1990-03-21 Expression von exogenen Polynukleotidsequenzen in Wirbeltieren
DE69032284T Expired - Lifetime DE69032284T2 (de) 1989-03-21 1990-03-21 Expression von exogenen polynukleotidsequenzen in wirbeltieren
DE69034078A Expired - Lifetime DE69034078D1 (de) 1989-03-21 1990-03-21 Expression von exogenen Polynukleotidsequenzen in Wirbeltieren
DE69034078T Expired - Lifetime DE69034078T2 (de) 1989-03-21 1990-03-21 Expression von exogenen Polynukleotidsequenzen in Wirbeltieren
DE69034168T Expired - Lifetime DE69034168T3 (de) 1989-03-21 1990-03-21 Expression von exogenen Polynukleotidsequenzen in Wirbeltieren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69032284A Revoked DE69032284D1 (de) 1989-03-21 1990-03-21 Expression von exogenen polynukleotidsequenzen in wirbeltieren

Family Applications After (4)

Application Number Title Priority Date Filing Date
DE69032284T Expired - Lifetime DE69032284T2 (de) 1989-03-21 1990-03-21 Expression von exogenen polynukleotidsequenzen in wirbeltieren
DE69034078A Expired - Lifetime DE69034078D1 (de) 1989-03-21 1990-03-21 Expression von exogenen Polynukleotidsequenzen in Wirbeltieren
DE69034078T Expired - Lifetime DE69034078T2 (de) 1989-03-21 1990-03-21 Expression von exogenen Polynukleotidsequenzen in Wirbeltieren
DE69034168T Expired - Lifetime DE69034168T3 (de) 1989-03-21 1990-03-21 Expression von exogenen Polynukleotidsequenzen in Wirbeltieren

Country Status (12)

Country Link
US (1) US20070218077A1 (de)
EP (3) EP1026253B2 (de)
JP (2) JP3250802B2 (de)
AT (3) AT240401T (de)
AU (1) AU5344190A (de)
CA (4) CA2489769A1 (de)
DE (6) DE69032284D1 (de)
DK (2) DK0737750T3 (de)
ES (2) ES2200016T3 (de)
FI (1) FI914427A0 (de)
NO (1) NO913700L (de)
WO (1) WO1990011092A1 (de)

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CA2049287A1 (en) 1990-09-22
EP0465529A1 (de) 1992-01-15
JP2001158751A (ja) 2001-06-12
NO913700L (no) 1991-11-11
FI914427D0 (de)
JP3683798B2 (ja) 2005-08-17
DK0737750T3 (da) 2003-09-01
NO913700D0 (no) 1991-09-19
CA2425745A1 (en) 1990-10-04
EP0737750B1 (de) 2003-05-14
ES2116269T3 (es) 1998-07-16
DK0465529T3 (da) 1998-10-05
WO1990011092A1 (en) 1990-10-04
FI914427A0 (fi) 1991-09-20
EP0465529A4 (en) 1992-08-26
US20070218077A1 (en) 2007-09-20
EP1026253B2 (de) 2012-12-19

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