DE69029406D1 - Polypeptid - Google Patents

Polypeptid

Info

Publication number
DE69029406D1
DE69029406D1 DE69029406T DE69029406T DE69029406D1 DE 69029406 D1 DE69029406 D1 DE 69029406D1 DE 69029406 T DE69029406 T DE 69029406T DE 69029406 T DE69029406 T DE 69029406T DE 69029406 D1 DE69029406 D1 DE 69029406D1
Authority
DE
Germany
Prior art keywords
sod
variants
pct
recombinant
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69029406T
Other languages
English (en)
Inventor
Stefan Marklund
Thomas Edlund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Symbicom AB
Original Assignee
Symbicom AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symbicom AB filed Critical Symbicom AB
Application granted granted Critical
Publication of DE69029406D1 publication Critical patent/DE69029406D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0089—Oxidoreductases (1.) acting on superoxide as acceptor (1.15)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
DE69029406T 1989-09-15 1990-09-17 Polypeptid Expired - Lifetime DE69029406D1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK455789A DK455789D0 (da) 1989-09-15 1989-09-15 Polypeptid
PCT/DK1990/000238 WO1991004315A1 (en) 1989-09-15 1990-09-17 A polypeptide

Publications (1)

Publication Number Publication Date
DE69029406D1 true DE69029406D1 (en) 1997-01-23

Family

ID=8134617

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69029406T Expired - Lifetime DE69029406D1 (en) 1989-09-15 1990-09-17 Polypeptid

Country Status (7)

Country Link
US (1) US5366729A (de)
EP (1) EP0593435B1 (de)
AT (1) ATE146219T1 (de)
AU (1) AU6444190A (de)
DE (1) DE69029406D1 (de)
DK (1) DK455789D0 (de)
WO (1) WO1991004315A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843641A (en) * 1993-02-26 1998-12-01 Massachusetts Institute Of Technology Methods for the daignosis, of familial amyotrophic lateral sclerosis
EP0627486A1 (de) * 1993-06-04 1994-12-07 N.V. Innogenetics S.A. Extra zellulare Superoxyd-Dismutase, Verfahren zur deren Herstellung und diese enthaltende Zusammensetzungen
DK75393D0 (da) * 1993-06-24 1993-06-24 Symbicom Ab Production of protein
US6127356A (en) 1993-10-15 2000-10-03 Duke University Oxidant scavengers
US5994339A (en) * 1993-10-15 1999-11-30 University Of Alabama At Birmingham Research Foundation Oxidant scavengers
US5747026A (en) * 1993-10-15 1998-05-05 University Of Alabama At Birmingham Research Foundation Antioxidants
AU3758695A (en) * 1994-09-20 1996-04-09 Duke University Oxidoreductase activity of manganic porphyrins
JPH08208511A (ja) * 1995-01-31 1996-08-13 Samu Kenkyusho:Kk 抗運動ニューロン疾患剤
AU769217B2 (en) * 1995-06-07 2004-01-22 Duke University Oxidant scavengers
DE69635304T2 (de) * 1995-06-07 2006-07-20 Duke University Faenger fuer oxidantien
ES2198767T3 (es) 1997-11-03 2004-02-01 Duke University Porfirinas sustituidas.
JP4648542B2 (ja) 1998-04-24 2011-03-09 デューク ユニバーシティ 置換ポルフィリン
US6190658B1 (en) 1998-05-08 2001-02-20 Webb-Waring Institute For Biomedical Research Genetically modified manganese superoxide dismutase for treating oxidative damage
MXPA01007451A (es) 1999-01-25 2004-03-10 Nat Jewish Med & Res Center Porfirinas sustituidas.
FR2805821B1 (fr) * 2000-03-01 2004-01-16 Diatos Sequences d'acides amines facilitant la penetration d'une substance d'interet a l'interieur des cellules et/ou des noyaux cellulaires
US8003595B2 (en) 2000-03-01 2011-08-23 Cellectis Amino acid sequences facilitating penetration of a substance of interest into cells and/or cell nuclei
DK1392328T3 (da) * 2001-01-19 2009-11-09 Nat Jewish Health Medikament til beskyttelse i radioterapi
FI20010898A0 (fi) * 2001-04-30 2001-04-30 Ylae Herttuala Seppo Ekstrasellulaarinen superoksididismutaasi (EC-SOD) geeniterapia restenoosoin ehkäisemiseksi
FI116851B (fi) 2001-05-03 2006-03-15 Fit Biotech Oyj Plc Ilmentämisvektori, sen käyttöjä ja menetelmä sen valmistamiseksi sekä sitä sisältäviä tuotteita
EP1439842A4 (de) * 2001-06-01 2009-09-02 Nat Jewish Med & Res Center Oxidantienfänger zur behandlung von diabetes oder zur verwendung bei der transplantation oder induktion von immuntoleranz
AU2002345699A1 (en) * 2001-06-13 2002-12-23 Webb-Waring Institute For Biomedical Research A diagnostic and prognostic method for evaluating ocular inflammation and oxidative stress and the treatment of the same
EP1513537A4 (de) 2002-06-07 2006-09-06 Univ Duke Substituierte porphyrine
EP1653989B1 (de) 2003-08-14 2009-07-15 Diatos Antibakterielle zusammensetzung, vor allem zur bekämpfung gramnegativer bakterien, umfassend ein peptid und ein vorteilhafterweise hydrophobes antibakterielles agens
US8318803B2 (en) * 2003-10-31 2012-11-27 Tae-Yoon Kim EC SOD and use thereof
EP1692187B1 (de) * 2003-10-31 2012-06-27 Tae-Yoon Kim EC SOD und zelltransduzierende EC SOD und Verwendung davon
US7332159B2 (en) 2004-09-30 2008-02-19 Board Of Regents Of The University Of Nebraska Method and composition for inhibiting reperfusion injury in the brain
ES2600469T3 (es) 2008-05-23 2017-02-09 National Jewish Health Un compuesto para su uso en el tratamiento de lesiones asociadas con la exposición al gas fosgeno o al gas de cloro
US8465413B2 (en) 2010-11-25 2013-06-18 Coloplast A/S Method of treating Peyronie's disease

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK145950C (da) * 1979-05-17 1983-09-26 Forenede Bryggerier As Fremgangsmaade til isolering af cu,zn-superoxid-dismutase fra vandige oploesninger indeholdende dette enzym sammen med ledsagende proteiner
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
JPS5729285A (en) * 1980-07-30 1982-02-17 Takeda Chem Ind Ltd Superoxide dismutase and its preparation
DE3377363D1 (en) * 1982-03-31 1988-08-18 Ajinomoto Kk Gene coding for interleukin-2 polypeptide, recombinant dna carrying said gene, cell lines possessing the recombinant dna,and method for producing interleukin-2 using said cells
IT1150598B (it) * 1982-12-14 1986-12-17 Ines Bianchi Procedimento per la purificazione della superossidodismutasi mediante cromatografia di affinita'
DE3486493T2 (de) * 1983-10-03 2003-05-22 Chiron Corp Klonieren von Superoxiddismutase und Expression in Mikroorganismen
US4742004A (en) * 1984-08-27 1988-05-03 Bio-Technology General Corp. Method for producing enzymatically active eucaryotic sod in bacteria
JPS61111690A (ja) * 1984-11-06 1986-05-29 Ube Ind Ltd 組換えｄｎａおよびその用途
DK402785D0 (da) * 1985-09-03 1985-09-03 Syn Tek Ab Fremgangsmaade til fremstilling af et enzym
EP0213628A3 (de) * 1985-09-03 1988-09-21 Yeda Research And Development Company, Ltd. Expression von Superoxiddismutase in eukaryotischen Zellen
CA1289092C (en) * 1987-01-15 1991-09-17 Robert A. Hallewell Thermostable human cu/zn superoxide dismutase muteins
EP0414915B1 (de) * 1989-03-06 1996-06-12 Suntory Limited Neue superoxyd-dismutase

Also Published As

Publication number Publication date
EP0593435A1 (de) 1994-04-27
US5366729A (en) 1994-11-22
AU6444190A (en) 1991-04-18
DK455789D0 (da) 1989-09-15
EP0593435B1 (de) 1996-12-11
ATE146219T1 (de) 1996-12-15
WO1991004315A1 (en) 1991-04-04

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