DE69005317D1 - Verfahren und Zwischenprodukte zur Herstellung von Isopropylestern von 3S-amino-2R-hydroxyalkansäuren. - Google Patents
Verfahren und Zwischenprodukte zur Herstellung von Isopropylestern von 3S-amino-2R-hydroxyalkansäuren.Info
- Publication number
- DE69005317D1 DE69005317D1 DE90300205T DE69005317T DE69005317D1 DE 69005317 D1 DE69005317 D1 DE 69005317D1 DE 90300205 T DE90300205 T DE 90300205T DE 69005317 T DE69005317 T DE 69005317T DE 69005317 D1 DE69005317 D1 DE 69005317D1
- Authority
- DE
- Germany
- Prior art keywords
- amino
- intermediates
- preparation
- isopropyl esters
- hydroxyalkanoic acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being saturated and containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
- C07C59/29—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/62—Three oxygen atoms, e.g. ascorbic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/86—Renin inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29986389A | 1989-01-19 | 1989-01-19 | |
US07/374,200 US4965372A (en) | 1989-01-19 | 1989-06-29 | Process and intermediates for isopropyl 3S-amino-2R-hydroxy-alkanoates |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69005317D1 true DE69005317D1 (de) | 1994-02-03 |
DE69005317T2 DE69005317T2 (de) | 1994-04-28 |
Family
ID=26971446
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE90300205T Expired - Fee Related DE69005317T2 (de) | 1989-01-19 | 1990-01-08 | Verfahren und Zwischenprodukte zur Herstellung von Isopropylestern von 3S-amino-2R-hydroxyalkansäuren. |
Country Status (17)
Country | Link |
---|---|
US (1) | US4965372A (de) |
EP (1) | EP0379288B1 (de) |
JP (1) | JPH0688929B2 (de) |
KR (1) | KR940000197B1 (de) |
AT (1) | ATE98953T1 (de) |
AU (1) | AU611603B2 (de) |
CA (1) | CA2007906A1 (de) |
DE (1) | DE69005317T2 (de) |
DK (1) | DK0379288T3 (de) |
ES (1) | ES2062317T3 (de) |
FI (1) | FI900292A0 (de) |
IE (1) | IE61797B1 (de) |
IL (1) | IL93039A0 (de) |
MY (1) | MY104896A (de) |
NO (1) | NO900261L (de) |
NZ (1) | NZ232153A (de) |
PT (1) | PT92879A (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5440247A (en) * | 1993-05-26 | 1995-08-08 | Kaplinsky; Cecil H. | Fast CMOS logic with programmable logic control |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3124140A (en) * | 1964-03-10 | Tobacco and flavoring composition | ||
JPS61236770A (ja) * | 1985-04-15 | 1986-10-22 | Kissei Pharmaceut Co Ltd | 新規なアミノ酸誘導体 |
US4599198A (en) * | 1985-08-02 | 1986-07-08 | Pfizer Inc. | Intermediates in polypeptide synthesis |
JPS61178955A (ja) * | 1985-12-02 | 1986-08-11 | Nippon Kayaku Co Ltd | スレオ−3−アミノ−2−ヒドロキシ−4−フエニル酪酸の製造法 |
EP0244083A3 (de) * | 1986-04-01 | 1989-11-15 | Kissei Pharmaceutical Co. Ltd. | Aminosäure-Derivate |
US4656269A (en) * | 1986-04-15 | 1987-04-07 | Kissei Pharmaceutical Co., Ltd. | Histidine derivatives |
MY103189A (en) * | 1986-10-31 | 1993-05-29 | Pfizer | Nor-statine and nor-cyclostatine polypeptides |
US4814342A (en) * | 1986-10-31 | 1989-03-21 | Pfizer Inc. | Nor-statine and nor-cyclostatine polypeptides |
-
1989
- 1989-06-29 US US07/374,200 patent/US4965372A/en not_active Expired - Fee Related
-
1990
- 1990-01-08 DE DE90300205T patent/DE69005317T2/de not_active Expired - Fee Related
- 1990-01-08 ES ES90300205T patent/ES2062317T3/es not_active Expired - Lifetime
- 1990-01-08 AT AT90300205T patent/ATE98953T1/de not_active IP Right Cessation
- 1990-01-08 EP EP90300205A patent/EP0379288B1/de not_active Expired - Lifetime
- 1990-01-08 DK DK90300205.3T patent/DK0379288T3/da active
- 1990-01-11 IL IL93039A patent/IL93039A0/xx unknown
- 1990-01-17 CA CA002007906A patent/CA2007906A1/en not_active Abandoned
- 1990-01-17 PT PT92879A patent/PT92879A/pt not_active Application Discontinuation
- 1990-01-17 MY MYPI90000078A patent/MY104896A/en unknown
- 1990-01-17 JP JP2008106A patent/JPH0688929B2/ja not_active Expired - Lifetime
- 1990-01-18 FI FI900292A patent/FI900292A0/fi not_active IP Right Cessation
- 1990-01-18 KR KR1019900000567A patent/KR940000197B1/ko not_active IP Right Cessation
- 1990-01-18 AU AU48568/90A patent/AU611603B2/en not_active Ceased
- 1990-01-18 NZ NZ232153A patent/NZ232153A/xx unknown
- 1990-01-18 NO NO90900261A patent/NO900261L/no unknown
- 1990-01-18 IE IE19290A patent/IE61797B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE98953T1 (de) | 1994-01-15 |
EP0379288B1 (de) | 1993-12-22 |
AU4856890A (en) | 1990-07-26 |
PT92879A (pt) | 1990-07-31 |
NZ232153A (en) | 1991-09-25 |
MY104896A (en) | 1994-06-30 |
EP0379288A1 (de) | 1990-07-25 |
KR940000197B1 (ko) | 1994-01-12 |
DE69005317T2 (de) | 1994-04-28 |
IE900192L (en) | 1990-07-19 |
ES2062317T3 (es) | 1994-12-16 |
FI900292A0 (fi) | 1990-01-18 |
NO900261D0 (no) | 1990-01-18 |
KR900011711A (ko) | 1990-08-02 |
CA2007906A1 (en) | 1990-07-19 |
NO900261L (no) | 1990-07-20 |
IE61797B1 (en) | 1994-11-30 |
AU611603B2 (en) | 1991-06-13 |
JPH0688929B2 (ja) | 1994-11-09 |
JPH02229134A (ja) | 1990-09-11 |
IL93039A0 (en) | 1990-11-05 |
US4965372A (en) | 1990-10-23 |
DK0379288T3 (da) | 1994-04-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |