DE60319388D1 - C6- UND C9-SUBSTITUIERTE CHROMENOÄ4,3-cÜISOXAZOLIN - Google Patents

C6- UND C9-SUBSTITUIERTE CHROMENOÄ4,3-cÜISOXAZOLIN

Info

Publication number
DE60319388D1
DE60319388D1 DE60319388T DE60319388T DE60319388D1 DE 60319388 D1 DE60319388 D1 DE 60319388D1 DE 60319388 T DE60319388 T DE 60319388T DE 60319388 T DE60319388 T DE 60319388T DE 60319388 D1 DE60319388 D1 DE 60319388D1
Authority
DE
Germany
Prior art keywords
cosoxazolines
chromenoe4
substituted
substituted chromenoe4
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60319388T
Other languages
English (en)
Other versions
DE60319388T2 (de
Inventor
Manuel Jesus Alcazar-Vaca
Jose Ignacio Andres-Gil
M Matesanz-Ballesteros
Margaretha Henrica Bakker
Antonius Adrianus Megens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of DE60319388D1 publication Critical patent/DE60319388D1/de
Publication of DE60319388T2 publication Critical patent/DE60319388T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE60319388T 2002-08-21 2003-08-19 C6- und C9-substituierte Chromeno[4,3-c]Isoxazoline und ihre Verwendung als Anti-Depressiva Expired - Lifetime DE60319388T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02078844 2002-08-21
EP02078844 2002-08-21
PCT/EP2003/009532 WO2004018482A2 (en) 2002-08-21 2003-08-19 C6- and c9-substituted chromeno[4, 3-c]isoxazoline derivatives and their use as anti-depressants

Publications (2)

Publication Number Publication Date
DE60319388D1 true DE60319388D1 (de) 2008-04-10
DE60319388T2 DE60319388T2 (de) 2009-02-19

Family

ID=31896931

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60319388T Expired - Lifetime DE60319388T2 (de) 2002-08-21 2003-08-19 C6- und C9-substituierte Chromeno[4,3-c]Isoxazoline und ihre Verwendung als Anti-Depressiva

Country Status (13)

Country Link
US (1) US7462717B2 (de)
EP (1) EP1532155B1 (de)
JP (1) JP4478570B2 (de)
CN (1) CN1303085C (de)
AR (1) AR041020A1 (de)
AT (1) ATE387455T1 (de)
AU (1) AU2003271567B2 (de)
CA (1) CA2495058C (de)
DE (1) DE60319388T2 (de)
ES (1) ES2301816T3 (de)
MY (1) MY134287A (de)
TW (1) TW200413392A (de)
WO (1) WO2004018482A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7265103B2 (en) * 2002-04-02 2007-09-04 Janssen Pharmaceutica Nv. Substituted amino isoxazoline derivatives and their use as anti-depressants
AR040967A1 (es) * 2002-08-12 2005-04-27 Janssen Pharmaceutica Nv Derivados de isoxazolina triciclicos c- sustituidos y su uso como anti- depresivos
WO2006056600A1 (en) * 2004-11-26 2006-06-01 Janssen Pharmaceutica N.V. Isoxazoline-indole derivatives with an improved antipsychotic and anxiolytic a ivity
WO2008086158A1 (en) * 2007-01-04 2008-07-17 Smithkline Beecham Corporation Benzodihydroquinazoline as pi3 kinase inhibitors
WO2024042361A1 (en) * 2022-08-24 2024-02-29 Sudo Biosciences Limited Tyk2 inhibitors and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9318691D0 (en) 1993-09-09 1993-10-27 Merck Sharp & Dohme Therapeutic agents
EP0874833A1 (de) 1996-01-05 1998-11-04 Hoechst Marion Roussel, Inc. 4,5-dihydronapht(1,2-c)isoxazole und derivate derselben mit zns-aktivität
KR100848898B1 (ko) 2001-02-21 2008-07-29 얀센 파마슈티카 엔.브이. 항우울제로서 이속사졸린 유도체
US7265103B2 (en) * 2002-04-02 2007-09-04 Janssen Pharmaceutica Nv. Substituted amino isoxazoline derivatives and their use as anti-depressants

Also Published As

Publication number Publication date
TW200413392A (en) 2004-08-01
CA2495058C (en) 2012-01-03
CN1303085C (zh) 2007-03-07
JP2005538143A (ja) 2005-12-15
US7462717B2 (en) 2008-12-09
ES2301816T3 (es) 2008-07-01
WO2004018482A2 (en) 2004-03-04
ATE387455T1 (de) 2008-03-15
MY134287A (en) 2007-11-30
AU2003271567A1 (en) 2004-03-11
CA2495058A1 (en) 2004-03-04
EP1532155A2 (de) 2005-05-25
JP4478570B2 (ja) 2010-06-09
AR041020A1 (es) 2005-04-27
DE60319388T2 (de) 2009-02-19
CN1675223A (zh) 2005-09-28
US20060122167A1 (en) 2006-06-08
EP1532155B1 (de) 2008-02-27
AU2003271567B2 (en) 2009-12-24
WO2004018482A8 (en) 2005-03-24
WO2004018482A3 (en) 2004-04-01

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Legal Events

Date Code Title Description
8381 Inventor (new situation)

Inventor name: ANDRES-GIL, JOSE I., TOLEDO, ES

Inventor name: ALCAZAR-VACA, MANUEL, TOLEDO, ES

Inventor name: MATESANZ-BALLESTEROS, M., TOLEDO, ES

Inventor name: BAKKER, MARGARETHA HENRICA, 64342 SEEHEIM-JUGE, DE

Inventor name: MEGENS, ANTONIUS ADRIANUS, BEERSE, BE

8364 No opposition during term of opposition