DE60222143D1 - USE OF NON-FEMINATING ESTROGENES AS RETINOPROTECTIVE AGENTS FOR THE TREATMENT OF GLAUCOMA - Google Patents

USE OF NON-FEMINATING ESTROGENES AS RETINOPROTECTIVE AGENTS FOR THE TREATMENT OF GLAUCOMA

Info

Publication number
DE60222143D1
DE60222143D1 DE60222143T DE60222143T DE60222143D1 DE 60222143 D1 DE60222143 D1 DE 60222143D1 DE 60222143 T DE60222143 T DE 60222143T DE 60222143 T DE60222143 T DE 60222143T DE 60222143 D1 DE60222143 D1 DE 60222143D1
Authority
DE
Germany
Prior art keywords
feminating
estrogenes
glaucoma
treatment
retinoprotective
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60222143T
Other languages
German (de)
Other versions
DE60222143T2 (en
Inventor
Iok-Hou Pang
Abbot F Clark
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Inc
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Application granted granted Critical
Publication of DE60222143D1 publication Critical patent/DE60222143D1/en
Publication of DE60222143T2 publication Critical patent/DE60222143T2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/566Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
DE60222143T 2001-09-05 2002-09-03 USE OF NON-FEMINATING ESTROGENES AS RETINOPROTECTIVE AGENTS FOR THE TREATMENT OF GLAUCOMA Expired - Lifetime DE60222143T2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31722501P 2001-09-05 2001-09-05
US317225P 2001-09-05
PCT/US2002/027969 WO2003020284A1 (en) 2001-09-05 2002-09-03 Use of non-feminizing estrogens as retinoprotective agents for the treatment of glaucoma

Publications (2)

Publication Number Publication Date
DE60222143D1 true DE60222143D1 (en) 2007-10-11
DE60222143T2 DE60222143T2 (en) 2008-06-05

Family

ID=23232682

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60222143T Expired - Lifetime DE60222143T2 (en) 2001-09-05 2002-09-03 USE OF NON-FEMINATING ESTROGENES AS RETINOPROTECTIVE AGENTS FOR THE TREATMENT OF GLAUCOMA

Country Status (17)

Country Link
EP (1) EP1423125B1 (en)
JP (1) JP2005501888A (en)
KR (1) KR100894385B1 (en)
CN (1) CN1551773A (en)
AR (1) AR038451A1 (en)
AT (1) ATE371455T1 (en)
AU (1) AU2002326807B2 (en)
BR (1) BR0212274A (en)
CA (1) CA2458468C (en)
DE (1) DE60222143T2 (en)
ES (1) ES2289134T3 (en)
HK (1) HK1064947A1 (en)
MX (1) MXPA04002098A (en)
PL (1) PL206249B1 (en)
TW (1) TWI320712B (en)
WO (1) WO2003020284A1 (en)
ZA (1) ZA200401313B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040214806A1 (en) 2002-09-03 2004-10-28 Iok-Hou Pang Use of non-feminizing estrogens as retinoprotective agents for the treatment of glaucoma
WO2004093882A1 (en) * 2003-04-18 2004-11-04 Advanced Medicine Research Institute Remedies for diseases to be applied to eye
WO2004091630A1 (en) * 2003-04-18 2004-10-28 Advanced Medicine Research Institute Remedies for diseases to be applied to eye

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993010141A2 (en) * 1991-11-22 1993-05-27 Alcon Laboratories, Inc. Angiostatic steroids
US6197833B1 (en) * 1995-07-24 2001-03-06 Apollo Biopharmaceutics, Inc. Neuroprotective effects of polycyclic phenolic compounds
US5521168A (en) * 1994-10-13 1996-05-28 Alcon Laboratories, Inc. Estrogen metabolites for lowering intraocular pressure
AU8838601A (en) * 2000-11-27 2002-06-03 Entremed Inc Antiangiogenic agents

Also Published As

Publication number Publication date
KR100894385B1 (en) 2009-04-22
EP1423125A4 (en) 2005-02-09
MXPA04002098A (en) 2004-06-07
HK1064947A1 (en) 2005-02-08
PL206249B1 (en) 2010-07-30
CN1551773A (en) 2004-12-01
DE60222143T2 (en) 2008-06-05
PL374243A1 (en) 2005-10-03
WO2003020284A1 (en) 2003-03-13
ZA200401313B (en) 2005-05-11
EP1423125B1 (en) 2007-08-29
EP1423125A1 (en) 2004-06-02
CA2458468C (en) 2010-08-24
CA2458468A1 (en) 2003-03-13
ES2289134T3 (en) 2008-02-01
AR038451A1 (en) 2005-01-19
AU2002326807B2 (en) 2007-08-23
JP2005501888A (en) 2005-01-20
KR20040033012A (en) 2004-04-17
TWI320712B (en) 2010-02-21
ATE371455T1 (en) 2007-09-15
BR0212274A (en) 2004-10-19

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Legal Events

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