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DE60216300D1 - Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption - Google Patents

Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption

Info

Publication number
DE60216300D1
DE60216300D1 DE2002616300 DE60216300A DE60216300D1 DE 60216300 D1 DE60216300 D1 DE 60216300D1 DE 2002616300 DE2002616300 DE 2002616300 DE 60216300 A DE60216300 A DE 60216300A DE 60216300 D1 DE60216300 D1 DE 60216300D1
Authority
DE
Grant status
Grant
Patent type
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE2002616300
Other languages
English (en)
Other versions
DE60216300T2 (de )
Inventor
R Davis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp & Dohme Corp
Original Assignee
Merck Sharp & Dohme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
DE2002616300 2001-09-21 2002-09-19 Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption Active DE60216300D1 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US32394201 true 2001-09-21 2001-09-21
PCT/US2002/029652 WO2003026643A3 (en) 2001-09-21 2002-09-19 Treatment of xanthoma with azetidinone derivatives as sterol absorption inhibitors

Publications (1)

Publication Number Publication Date
DE60216300D1 true DE60216300D1 (de) 2007-01-04

Family

ID=23261375

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2002616300 Active DE60216300T2 (de) 2001-09-21 2002-09-19 Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption
DE2002616300 Active DE60216300D1 (de) 2001-09-21 2002-09-19 Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE2002616300 Active DE60216300T2 (de) 2001-09-21 2002-09-19 Behandlung von xanthom mittels azetidinon-derivate als hemmer der sterol absorption

Country Status (8)

Country Link
US (2) US7132415B2 (de)
EP (1) EP1429756B1 (de)
JP (1) JP2005504091A (de)
CA (1) CA2460340C (de)
DE (2) DE60216300T2 (de)
DK (1) DK1429756T3 (de)
ES (1) ES2272776T3 (de)
WO (1) WO2003026643A3 (de)

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US7871998B2 (en) 2003-12-23 2011-01-18 Astrazeneca Ab Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity
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US7803838B2 (en) 2004-06-04 2010-09-28 Forest Laboratories Holdings Limited Compositions comprising nebivolol
EP1688161A1 (de) * 2004-11-02 2006-08-09 Switch Biotech Aktiengesellschaft Verwendung von pirlindol zur Behandlung der Krankheiten gekennzeichnet durch Proliferation von t-Lymphozyten und/oder Hyperproliferation von Keratinozyten, ins besondere atopischer Dermatitis und Psoriasis
CN101228123A (zh) 2005-06-20 2008-07-23 阿斯利康(瑞典)有限公司 新型2-氮杂环丁烷酮衍生物及其作为胆固醇吸收抑制剂治疗高脂血症的应用
KR20080019709A (ko) 2005-06-22 2008-03-04 아스트라제네카 아베 고지혈성 병태의 치료를 위한 콜레스테롤 흡수억제제로서의 신규한 2-아제티디논 유도체
JP2008546774A (ja) 2005-06-22 2008-12-25 アストラゼネカ アクチボラグ 化合物vi
JP2009538277A (ja) 2006-04-27 2009-11-05 アストラゼネカ アクチボラグ コレステロール吸収阻害活性をもつジフェニルアゼチジノン誘導体
ES2557895T3 (es) 2010-03-19 2016-01-29 Pfizer Inc Derivados de 2,3-dihidro-1H-inden-1-il-2,7-diazaespiro[3.6]nonano y su uso como antagonistas o agonistas inversos del receptor de grelina
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US20140275090A1 (en) 2013-03-15 2014-09-18 Lumena Pharmaceuticals, Inc. Bile acid recycling inhibitors for treatment of primary sclerosing cholangitis and inflammatory bowel disease
CN105228615A (zh) 2013-03-15 2016-01-06 鲁美纳医药公司 用于治疗巴雷特食管和胃食管返流疾病的胆汁酸再循环抑制剂

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EP1429756B1 (de) 2006-11-22 grant
CA2460340C (en) 2011-02-15 grant
EP1429756A2 (de) 2004-06-23 application
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