DE602005020742D1 - Sequenzamplifikations- und -nachweisverfahrens - Google Patents

Sequenzamplifikations- und -nachweisverfahrens

Info

Publication number
DE602005020742D1
DE602005020742D1 DE602005020742T DE602005020742T DE602005020742D1 DE 602005020742 D1 DE602005020742 D1 DE 602005020742D1 DE 602005020742 T DE602005020742 T DE 602005020742T DE 602005020742 T DE602005020742 T DE 602005020742T DE 602005020742 D1 DE602005020742 D1 DE 602005020742D1
Authority
DE
Germany
Prior art keywords
fluid
lysis
unit
sample
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005020742T
Other languages
English (en)
Inventor
F Schonfeld
Germar F Von
Frank Karlsen
Jan Lichtenberg
Sabeth Verpoorte
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norchip AS
Original Assignee
Norchip AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norchip AS filed Critical Norchip AS
Publication of DE602005020742D1 publication Critical patent/DE602005020742D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44782—Apparatus specially adapted therefor of a plurality of samples
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/048—Function or devices integrated in the closure enabling gas exchange, e.g. vents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/049—Valves integrated in closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4005—Concentrating samples by transferring a selected component through a membrane
    • G01N2001/4016—Concentrating samples by transferring a selected component through a membrane being a selective membrane, e.g. dialysis or osmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE602005020742T 2004-01-28 2005-01-28 Sequenzamplifikations- und -nachweisverfahrens Active DE602005020742D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0401868A GB2416030B (en) 2004-01-28 2004-01-28 A diagnostic system for carrying out a nucleic acid sequence amplification and detection process
PCT/GB2005/000308 WO2005073691A1 (en) 2004-01-28 2005-01-28 A diagnostic system for carrying out a nucleic acid sequence amplification and detection process

Publications (1)

Publication Number Publication Date
DE602005020742D1 true DE602005020742D1 (de) 2010-06-02

Family

ID=31971613

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005020742T Active DE602005020742D1 (de) 2004-01-28 2005-01-28 Sequenzamplifikations- und -nachweisverfahrens

Country Status (18)

Country Link
US (1) US20080227185A1 (de)
EP (1) EP1714134B1 (de)
JP (1) JP4921177B2 (de)
KR (1) KR20070027507A (de)
CN (1) CN1973197B (de)
AT (1) ATE465401T1 (de)
AU (1) AU2005208085B8 (de)
BR (1) BRPI0507200A (de)
CA (1) CA2554452A1 (de)
DE (1) DE602005020742D1 (de)
EA (1) EA011753B1 (de)
GB (1) GB2416030B (de)
IL (1) IL177122A (de)
MX (1) MXPA06008469A (de)
NO (1) NO20063782L (de)
NZ (1) NZ548801A (de)
WO (1) WO2005073691A1 (de)
ZA (1) ZA200606197B (de)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006002258B4 (de) 2006-01-17 2008-08-21 Siemens Ag Modul zur Aufbereitung einer biologischen Probe, Biochip-Satz und Verwendung des Moduls
KR100785010B1 (ko) * 2006-04-06 2007-12-11 삼성전자주식회사 수소 결합을 이용하여 고체 지지체의 친수성 표면 상에서핵산 정제 방법 및 장치
JP4685691B2 (ja) * 2006-04-13 2011-05-18 株式会社日立ソリューションズ 検査チップ及び検査チップシステム
EP2016415B1 (de) 2006-04-21 2013-08-14 Nanobiosym, Inc. Einzelmolekülplattform für wirkstoffentdeckung: verfahren für wirkstoffentdeckung, einschliesslich der entdeckung von krebsmitteln und viruziden
JP4759451B2 (ja) * 2006-06-16 2011-08-31 株式会社日立ソリューションズ 生体物質の前処理チップ及び前処理チップシステム
US7608399B2 (en) 2006-06-26 2009-10-27 Blood Cell Storage, Inc. Device and method for extraction and analysis of nucleic acids from biological samples
JP2008051803A (ja) * 2006-07-28 2008-03-06 Sharp Corp 分析用マイクロ流路デバイス
US20080264842A1 (en) * 2006-10-11 2008-10-30 Arcxis Biotechnologies, Llc Disposable micropurification cards, methods, and systems thereof
EP1970121A1 (de) * 2006-12-15 2008-09-17 Universiteit Leiden Eine mikrofluidische Chipgestaltung mit Kapillaren
EP1942058A1 (de) 2007-01-08 2008-07-09 Nutricia N.V. Verpackung für fließfähige Waren, insbesondere Lebensmittel, und Verwendung solcher Verpackungen bei Transport, Aufmachung und Verzehr
NZ580375A (en) 2007-04-04 2012-02-24 Netbio Inc Integrated nucleic acid analysis
GB0710957D0 (en) * 2007-06-07 2007-07-18 Norchip As A device for carrying out cell lysis and nucleic acid extraction
WO2009117167A1 (en) 2008-01-02 2009-09-24 Blood Cell Storage, Inc. Devices and processes for nucleic acid extraction
US8961902B2 (en) * 2008-04-23 2015-02-24 Bioscale, Inc. Method and apparatus for analyte processing
DE102008050092A1 (de) 2008-10-06 2010-04-08 Hach Lange Gmbh Mobile Wasser-Analyseanordnung
GB0820720D0 (en) * 2008-11-12 2008-12-17 Norchip As Method for worldwide screening of pre-cancer epithelial disease of the cervix
US10196700B2 (en) 2009-03-24 2019-02-05 University Of Chicago Multivolume devices, kits and related methods for quantification and detection of nucleic acids and other analytes
US9447461B2 (en) 2009-03-24 2016-09-20 California Institute Of Technology Analysis devices, kits, and related methods for digital quantification of nucleic acids and other analytes
WO2010111265A1 (en) 2009-03-24 2010-09-30 University Of Chicago Slip chip device and methods
US9464319B2 (en) 2009-03-24 2016-10-11 California Institute Of Technology Multivolume devices, kits and related methods for quantification of nucleic acids and other analytes
EP2443254A2 (de) 2009-06-15 2012-04-25 NetBio, Inc. Verbesserte verfahren für forensische dna-quantifizierung
GB0912509D0 (en) 2009-07-17 2009-08-26 Norchip As A microfabricated device for metering an analyte
KR101626846B1 (ko) * 2009-12-22 2016-06-02 삼성전자주식회사 핵산 분리 방법 및 장치
US20110091873A1 (en) * 2009-10-21 2011-04-21 Microfluidic Systems, Inc. Integrated sample preparation and amplification for nucleic acid detection from biological samples
US20110111386A1 (en) * 2009-11-11 2011-05-12 Norchip As Cervical cell collection method
US9144799B2 (en) * 2009-11-24 2015-09-29 Lawrence Livermore National Security, Llc Modular microfluidic system for biological sample preparation
WO2012122564A2 (en) 2011-03-10 2012-09-13 Xagenic, Inc. Diagnostic and sample preparation devices and methods
CN103917661A (zh) 2011-05-12 2014-07-09 网络百奥有限公司 用于快速多重扩增str基因座的方法和组合物
US8629264B2 (en) 2011-05-19 2014-01-14 Blood Cell Storage, Inc. Gravity flow fluidic device for nucleic acid extraction
ITMI20112080A1 (it) * 2011-11-16 2013-05-17 Eugenio Iannone Sistema di diagnosi preliminare.
KR20130065279A (ko) * 2011-12-09 2013-06-19 한국전자통신연구원 바이오칩 및 이를 이용한 검체 정량 주입 방법
KR101406347B1 (ko) * 2011-12-12 2014-06-12 나노바이오시스 주식회사 핵산 추출용 미세유동 칩, 이를 포함하는 핵산 추출 장치, 및 이를 이용하는 핵산 추출 방법
KR101915675B1 (ko) * 2012-02-07 2018-11-06 주식회사 미코바이오메드 초고속 핵산 추출 장치, 및 이를 이용하는 핵산 추출 방법
KR102041217B1 (ko) * 2012-05-30 2019-11-07 주식회사 미코바이오메드 다-채널 하향 액체 주입 장치, 이를 포함하는 핵산 추출 장치, 및 이를 이용한 핵산 추출 방법
US9399986B2 (en) * 2012-07-31 2016-07-26 General Electric Company Devices and systems for isolating biomolecules and associated methods thereof
US20150259671A1 (en) * 2012-07-31 2015-09-17 General Electric Company Devices and systems for isolating biomolecules and associated methods thereof
JP1628115S (de) 2012-10-24 2019-04-01
US20140322706A1 (en) 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
WO2014113598A2 (en) * 2013-01-16 2014-07-24 The Regents Of The University Of California Microfluidic devices to extract, concentrate and isolate molecules
US20150361419A1 (en) * 2013-01-21 2015-12-17 Nanobiosys Inc. Microfluidic chip for extracting nucleic acids, device for extracting nucleic acids comprising same, and method for extracting nucleic acids using same
EP4144439A1 (de) 2013-03-15 2023-03-08 Nanobiosym, Inc. System zur analyse einer biologischen probe
AU2014235532B2 (en) 2013-03-15 2018-08-09 Genmark Diagnostics, Inc. Systems, methods, and apparatus for manipulating deformable fluid vessels
US10933417B2 (en) 2013-03-15 2021-03-02 Nanobiosym, Inc. Systems and methods for mobile device analysis of nucleic acids and proteins
US9506934B2 (en) * 2013-04-29 2016-11-29 Honeywell International Inc. Polymer test cartridge mixer for cell lysis
GB2516669B (en) 2013-07-29 2015-09-09 Atlas Genetics Ltd A method for processing a liquid sample in a fluidic cartridge
USD881409S1 (en) 2013-10-24 2020-04-14 Genmark Diagnostics, Inc. Biochip cartridge
US9498778B2 (en) 2014-11-11 2016-11-22 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
CN103602583A (zh) * 2013-11-07 2014-02-26 苏州汶颢芯片科技有限公司 一种集成式多功能微流控芯片
CN103592209B (zh) * 2013-11-27 2016-05-04 武汉武大绿洲生物技术有限公司 一种黑胸大蠊浓核病毒定性定量的检测方法及应用
CN103743607A (zh) * 2014-01-20 2014-04-23 厦门大学 一种用于食品样品检测前处理的芯片卡盒
CN105277725B (zh) * 2014-07-01 2017-03-29 清华大学 一种用于核酸分析检测的集成化微流控系统
CN104312913B (zh) * 2014-10-17 2016-05-11 复旦大学附属华山医院 整合全血核酸提取、扩增即可视化检测肿瘤基因突变的微流控芯片及其应用
US9598722B2 (en) 2014-11-11 2017-03-21 Genmark Diagnostics, Inc. Cartridge for performing assays in a closed sample preparation and reaction system
US10005080B2 (en) 2014-11-11 2018-06-26 Genmark Diagnostics, Inc. Instrument and cartridge for performing assays in a closed sample preparation and reaction system employing electrowetting fluid manipulation
CN104560636A (zh) * 2014-12-30 2015-04-29 北京理工大学 一种细胞预处理装置和方法
US11207681B2 (en) 2015-07-17 2021-12-28 Delta Electronics, Inc. Method for extracting nucleic acid and extraction cassette thereof
TWI591182B (zh) 2015-07-17 2017-07-11 台達電子工業股份有限公司 核酸萃取裝置
US11491482B2 (en) 2015-07-17 2022-11-08 Delta Electronics, Inc. Method for extracting nucleic acid and extraction cassette thereof
CN110004141A (zh) * 2017-12-26 2019-07-12 台达电子工业股份有限公司 核酸萃取方法及其萃取卡匣
CN105349401B (zh) * 2015-10-14 2018-03-27 安徽易康达光电科技有限公司 一种多功能的集成化微流控核酸分析芯片及制备和分析方法
US10376885B2 (en) 2015-11-04 2019-08-13 Lehigh University Microfluidic concentrator for label-free, continuous nanoparticle processing
CN105296349A (zh) * 2015-11-20 2016-02-03 青岛意诚融智生物仪器有限公司 一种用于dna快速检测的微流控芯片、检测系统和装置
CA3012680A1 (en) 2016-01-29 2017-08-03 Purigen Biosystems, Inc. Isotachophoresis for purification of nucleic acids
DE102016222032A1 (de) * 2016-11-10 2018-05-17 Robert Bosch Gmbh Mikrofluidische Vorrichtung und Verfahren zur Analyse von Nukleinsäuren
EP3611508B1 (de) * 2017-05-16 2022-08-03 SK Telecom Co., Ltd. Vorrichtung zur nukleinsäureanalyse unter verwendung einer kassette
CN111432919B (zh) 2017-08-02 2022-08-02 普瑞珍生物系统公司 用于等速电泳的系统、设备和方法
FR3088340B1 (fr) * 2018-11-12 2021-01-22 Commissariat Energie Atomique Systeme automatise de preparation, de detection et d'analyse d'un echantillon fluidique
CN109355283B (zh) * 2018-11-27 2023-05-05 中国科学院上海技术物理研究所 一种适用于空间的核酸自动提取装置
EP3995563A4 (de) * 2019-07-01 2022-10-05 Shenyi Biotech (Hangzhou) Co., Ltd. Neues verfahren zur durchführung einer pcr-reaktion unter verwendung eines umfassenden pcr-reaktionssystems
CN110257245A (zh) * 2019-07-16 2019-09-20 东莞博识生物科技有限公司 核酸检测试剂卡
US20220325272A1 (en) * 2019-09-20 2022-10-13 Siemens Healthcare Diagnostics Inc. Sample preparation apparatus and multi-well plate with pcr chip
JP7164505B2 (ja) * 2019-10-02 2022-11-01 積水化学工業株式会社 マイクロ流路チップ
JP2021065112A (ja) * 2019-10-18 2021-04-30 国立大学法人東海国立大学機構 植物物質検出用流路チップおよび植物物質検出装置
AU2021202502A1 (en) * 2020-04-29 2021-11-18 Teleflex Medical Incorporated Method of identifying severe acute respiratory syndrome corona virus 2 (sars-cov-2) ribonucleic acid (rna)
CN111944682A (zh) * 2020-08-14 2020-11-17 上海前瞻创新研究院有限公司 一种核酸检测芯片、制备方法及核酸检测方法
US20220333048A1 (en) * 2020-09-22 2022-10-20 Boe Technology Group Co., Ltd. Nucleic acid extraction microfluidic chip, and nucleic acid extraction device and extraction method
TWD218529S (zh) * 2020-09-30 2022-05-01 富佳生技股份有限公司 核酸檢測儀之圖形化使用者介面
DE102021203409A1 (de) 2021-04-07 2022-10-13 Robert Bosch Gesellschaft mit beschränkter Haftung Verfahren zum Nachweis aktiver Viren
GB2605956A (en) 2021-04-14 2022-10-26 Univ Of South Eastern Norway Systems, apparatus and methods for extracting and analysing cellular material
KR20230014169A (ko) * 2021-07-21 2023-01-30 주식회사 위즈바이오솔루션 시료 전처리 카트리지 장치 및 이를 이용한 시료 전처리 방법
WO2023181813A1 (ja) * 2022-03-22 2023-09-28 京セラ株式会社 核酸増幅方法、核酸増幅システム、ウイルス検出方法、及びウイルス検出システム

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1338505C (en) * 1989-02-03 1996-08-06 John Bruce Findlay Containment cuvette for pcr and method of use
US5229297A (en) * 1989-02-03 1993-07-20 Eastman Kodak Company Containment cuvette for PCR and method of use
US6403367B1 (en) * 1994-07-07 2002-06-11 Nanogen, Inc. Integrated portable biological detection system
JP3834357B2 (ja) * 1996-07-10 2006-10-18 オリンパス株式会社 小型分析装置及びその駆動方法
US6074827A (en) * 1996-07-30 2000-06-13 Aclara Biosciences, Inc. Microfluidic method for nucleic acid purification and processing
DE19700364A1 (de) * 1997-01-08 1998-07-09 Bayer Ag Elektrokinetische Probenvorbereitung
DK1179585T3 (da) * 1997-12-24 2008-11-10 Cepheid Indretning og fremgangsmåde til lysis
EP0987327A1 (de) * 1998-09-14 2000-03-22 QIAGEN GmbH Methode für die Reinigung kovalent geschlossener zirkulärer DNS
US6572830B1 (en) * 1998-10-09 2003-06-03 Motorola, Inc. Integrated multilayered microfludic devices and methods for making the same
US6887693B2 (en) * 1998-12-24 2005-05-03 Cepheid Device and method for lysing cells, spores, or microorganisms
US6942771B1 (en) * 1999-04-21 2005-09-13 Clinical Micro Sensors, Inc. Microfluidic systems in the electrochemical detection of target analytes
DK1181098T4 (da) * 1999-05-28 2011-09-26 Cepheid Patron til udførelse af en kemisk reaktion
AU2082701A (en) * 1999-12-09 2001-06-18 Motorola, Inc. Multilayered microfluidic devices for analyte reactions
FR2813207B1 (fr) * 2000-08-28 2002-10-11 Bio Merieux Carte reactionnelle et utilisation d'une telle carte
JP2002236131A (ja) * 2000-12-08 2002-08-23 Minolta Co Ltd マイクロチップ
WO2003011768A2 (en) * 2001-08-01 2003-02-13 Datascope Investment Corp. Microfluidic device for molecular analysis
US7338760B2 (en) * 2001-10-26 2008-03-04 Ntu Ventures Private Limited Sample preparation integrated chip
EP1546412B1 (de) * 2002-10-02 2014-05-21 California Institute Of Technology MIKROFLUIDISCHE NUKLEINSûUREANALYSE
US20040086872A1 (en) * 2002-10-31 2004-05-06 Childers Winthrop D. Microfluidic system for analysis of nucleic acids
CA3171720C (en) * 2002-12-26 2024-01-09 Meso Scale Technologies, Llc. Methods for conducting electrochemiluminescence measurements
DE10319045A1 (de) * 2003-04-25 2004-12-09 november Aktiengesellschaft Gesellschaft für Molekulare Medizin Vorrichtung und Verfahren zur Aufbereitung Biopolymerhaltiger Flüssigkeiten
JP4455014B2 (ja) * 2003-11-07 2010-04-21 セイコーインスツル株式会社 検査用マイクロチップおよび検査装置と検査方法

Also Published As

Publication number Publication date
AU2005208085B8 (en) 2011-02-24
KR20070027507A (ko) 2007-03-09
GB2416030B (en) 2008-07-23
CN1973197B (zh) 2010-12-15
EP1714134B1 (de) 2010-04-21
WO2005073691A1 (en) 2005-08-11
GB0401868D0 (en) 2004-03-03
MXPA06008469A (es) 2009-03-11
JP2007519917A (ja) 2007-07-19
CN1973197A (zh) 2007-05-30
BRPI0507200A (pt) 2007-06-12
US20080227185A1 (en) 2008-09-18
GB2416030A (en) 2006-01-11
IL177122A0 (en) 2006-12-10
IL177122A (en) 2011-07-31
EA011753B1 (ru) 2009-06-30
AU2005208085B2 (en) 2010-12-16
EP1714134A1 (de) 2006-10-25
NO20063782L (no) 2006-10-19
ATE465401T1 (de) 2010-05-15
EA200601377A1 (ru) 2007-02-27
CA2554452A1 (en) 2005-08-11
AU2005208085A1 (en) 2005-08-11
JP4921177B2 (ja) 2012-04-25
NZ548801A (en) 2010-12-24
ZA200606197B (en) 2008-02-27

Similar Documents

Publication Publication Date Title
DE602005020742D1 (de) Sequenzamplifikations- und -nachweisverfahrens
US10752936B2 (en) Device for analyzing a biological sample
JP2007519917A5 (de)
CN112195099B (zh) 一种用于核酸检测的微流控芯片
RU2380418C1 (ru) Сменный микрофлюидный модуль для автоматизированного выделения и очистки нуклеиновых кислот из биологических образцов и способ выделения и очистки нуклеиновых кислот с его использованием
WO2013020089A3 (en) Microfluidic systems and methods for processing fluids
CN104136596A (zh) 样品制备、处理和分析系统
CN105296349A (zh) 一种用于dna快速检测的微流控芯片、检测系统和装置
WO2007024798A3 (en) Apparatus, system, and method using immiscible-fluid-discrete-volumes
WO2004065010A3 (en) Method and system for microfluidic manipulation, amplification and analysis of fluids, for example, bacteria assays and antiglobulin testing
WO2003060157A3 (en) Fluid manipulation in a microfabricated reaction chamber system
WO2010130762A9 (en) Apparatus for and method of automated processing of biological samples
WO2010067019A3 (fr) Systeme automatise de lyse de microorganismes presents dans un echantillon, d'extraction et de purification des acides nucleiques desdits microorganismes aux fins d'analyse
JP2011530084A (ja) 汎用システム中での標的生物学的分子の選択的単離のための方法およびシステム
US11905550B2 (en) Process for preparing a biological sample
CN205170857U (zh) 一种用于dna快速检测的微流控芯片、检测系统和装置
CN104893963A (zh) 用于捕获空气中真菌孢子的微流控芯片及其制备方法
CN113684118B (zh) 一种集成核酸分析芯片
CN103173432B (zh) 分离核酸的方法及装置
CN205152235U (zh) 一种用于基因分型检测的微流控芯片、检测系统和装置
CN103484353A (zh) 基于滤纸的生物大分子提取装置
US10160943B2 (en) Method and microfluidic system for processing organic cells and manufacturing method for producing a microfluidic system for processing organic cells
CN104087506B (zh) 一种高通量单细胞反转录pcr分析装置
CN107937242B (zh) 一种基于纸基的dna电固相萃取方法与装置
CN207336192U (zh) 一种用于96孔板的真空浓缩装置

Legal Events

Date Code Title Description
8364 No opposition during term of opposition