DE602005020742D1 - Sequenzamplifikations- und -nachweisverfahrens - Google Patents
Sequenzamplifikations- und -nachweisverfahrensInfo
- Publication number
- DE602005020742D1 DE602005020742D1 DE602005020742T DE602005020742T DE602005020742D1 DE 602005020742 D1 DE602005020742 D1 DE 602005020742D1 DE 602005020742 T DE602005020742 T DE 602005020742T DE 602005020742 T DE602005020742 T DE 602005020742T DE 602005020742 D1 DE602005020742 D1 DE 602005020742D1
- Authority
- DE
- Germany
- Prior art keywords
- fluid
- lysis
- unit
- sample
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 230000003321 amplification Effects 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 238000003199 nucleic acid amplification method Methods 0.000 title 1
- 239000012530 fluid Substances 0.000 abstract 14
- 230000009089 cytolysis Effects 0.000 abstract 7
- 150000007523 nucleic acids Chemical class 0.000 abstract 6
- 102000039446 nucleic acids Human genes 0.000 abstract 6
- 108020004707 nucleic acids Proteins 0.000 abstract 6
- 238000000605 extraction Methods 0.000 abstract 5
- 239000002245 particle Substances 0.000 abstract 3
- 239000003480 eluent Substances 0.000 abstract 2
- 238000002032 lab-on-a-chip Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44782—Apparatus specially adapted therefor of a plurality of samples
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
- B01L2300/048—Function or devices integrated in the closure enabling gas exchange, e.g. vents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
- B01L2300/049—Valves integrated in closure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4005—Concentrating samples by transferring a selected component through a membrane
- G01N2001/4016—Concentrating samples by transferring a selected component through a membrane being a selective membrane, e.g. dialysis or osmosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
- Y10T156/10—Methods of surface bonding and/or assembly therefor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Genetics & Genomics (AREA)
- Clinical Laboratory Science (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0401868A GB2416030B (en) | 2004-01-28 | 2004-01-28 | A diagnostic system for carrying out a nucleic acid sequence amplification and detection process |
PCT/GB2005/000308 WO2005073691A1 (en) | 2004-01-28 | 2005-01-28 | A diagnostic system for carrying out a nucleic acid sequence amplification and detection process |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602005020742D1 true DE602005020742D1 (de) | 2010-06-02 |
Family
ID=31971613
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602005020742T Active DE602005020742D1 (de) | 2004-01-28 | 2005-01-28 | Sequenzamplifikations- und -nachweisverfahrens |
Country Status (18)
Country | Link |
---|---|
US (1) | US20080227185A1 (de) |
EP (1) | EP1714134B1 (de) |
JP (1) | JP4921177B2 (de) |
KR (1) | KR20070027507A (de) |
CN (1) | CN1973197B (de) |
AT (1) | ATE465401T1 (de) |
AU (1) | AU2005208085B8 (de) |
BR (1) | BRPI0507200A (de) |
CA (1) | CA2554452A1 (de) |
DE (1) | DE602005020742D1 (de) |
EA (1) | EA011753B1 (de) |
GB (1) | GB2416030B (de) |
IL (1) | IL177122A (de) |
MX (1) | MXPA06008469A (de) |
NO (1) | NO20063782L (de) |
NZ (1) | NZ548801A (de) |
WO (1) | WO2005073691A1 (de) |
ZA (1) | ZA200606197B (de) |
Families Citing this family (81)
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DE102006002258B4 (de) | 2006-01-17 | 2008-08-21 | Siemens Ag | Modul zur Aufbereitung einer biologischen Probe, Biochip-Satz und Verwendung des Moduls |
KR100785010B1 (ko) * | 2006-04-06 | 2007-12-11 | 삼성전자주식회사 | 수소 결합을 이용하여 고체 지지체의 친수성 표면 상에서핵산 정제 방법 및 장치 |
JP4685691B2 (ja) * | 2006-04-13 | 2011-05-18 | 株式会社日立ソリューションズ | 検査チップ及び検査チップシステム |
EP2016415B1 (de) | 2006-04-21 | 2013-08-14 | Nanobiosym, Inc. | Einzelmolekülplattform für wirkstoffentdeckung: verfahren für wirkstoffentdeckung, einschliesslich der entdeckung von krebsmitteln und viruziden |
JP4759451B2 (ja) * | 2006-06-16 | 2011-08-31 | 株式会社日立ソリューションズ | 生体物質の前処理チップ及び前処理チップシステム |
US7608399B2 (en) | 2006-06-26 | 2009-10-27 | Blood Cell Storage, Inc. | Device and method for extraction and analysis of nucleic acids from biological samples |
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EP1970121A1 (de) * | 2006-12-15 | 2008-09-17 | Universiteit Leiden | Eine mikrofluidische Chipgestaltung mit Kapillaren |
EP1942058A1 (de) | 2007-01-08 | 2008-07-09 | Nutricia N.V. | Verpackung für fließfähige Waren, insbesondere Lebensmittel, und Verwendung solcher Verpackungen bei Transport, Aufmachung und Verzehr |
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US10196700B2 (en) | 2009-03-24 | 2019-02-05 | University Of Chicago | Multivolume devices, kits and related methods for quantification and detection of nucleic acids and other analytes |
US9447461B2 (en) | 2009-03-24 | 2016-09-20 | California Institute Of Technology | Analysis devices, kits, and related methods for digital quantification of nucleic acids and other analytes |
WO2010111265A1 (en) | 2009-03-24 | 2010-09-30 | University Of Chicago | Slip chip device and methods |
US9464319B2 (en) | 2009-03-24 | 2016-10-11 | California Institute Of Technology | Multivolume devices, kits and related methods for quantification of nucleic acids and other analytes |
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GB2605956A (en) | 2021-04-14 | 2022-10-26 | Univ Of South Eastern Norway | Systems, apparatus and methods for extracting and analysing cellular material |
KR20230014169A (ko) * | 2021-07-21 | 2023-01-30 | 주식회사 위즈바이오솔루션 | 시료 전처리 카트리지 장치 및 이를 이용한 시료 전처리 방법 |
WO2023181813A1 (ja) * | 2022-03-22 | 2023-09-28 | 京セラ株式会社 | 核酸増幅方法、核酸増幅システム、ウイルス検出方法、及びウイルス検出システム |
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CA1338505C (en) * | 1989-02-03 | 1996-08-06 | John Bruce Findlay | Containment cuvette for pcr and method of use |
US5229297A (en) * | 1989-02-03 | 1993-07-20 | Eastman Kodak Company | Containment cuvette for PCR and method of use |
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JP3834357B2 (ja) * | 1996-07-10 | 2006-10-18 | オリンパス株式会社 | 小型分析装置及びその駆動方法 |
US6074827A (en) * | 1996-07-30 | 2000-06-13 | Aclara Biosciences, Inc. | Microfluidic method for nucleic acid purification and processing |
DE19700364A1 (de) * | 1997-01-08 | 1998-07-09 | Bayer Ag | Elektrokinetische Probenvorbereitung |
DK1179585T3 (da) * | 1997-12-24 | 2008-11-10 | Cepheid | Indretning og fremgangsmåde til lysis |
EP0987327A1 (de) * | 1998-09-14 | 2000-03-22 | QIAGEN GmbH | Methode für die Reinigung kovalent geschlossener zirkulärer DNS |
US6572830B1 (en) * | 1998-10-09 | 2003-06-03 | Motorola, Inc. | Integrated multilayered microfludic devices and methods for making the same |
US6887693B2 (en) * | 1998-12-24 | 2005-05-03 | Cepheid | Device and method for lysing cells, spores, or microorganisms |
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DK1181098T4 (da) * | 1999-05-28 | 2011-09-26 | Cepheid | Patron til udførelse af en kemisk reaktion |
AU2082701A (en) * | 1999-12-09 | 2001-06-18 | Motorola, Inc. | Multilayered microfluidic devices for analyte reactions |
FR2813207B1 (fr) * | 2000-08-28 | 2002-10-11 | Bio Merieux | Carte reactionnelle et utilisation d'une telle carte |
JP2002236131A (ja) * | 2000-12-08 | 2002-08-23 | Minolta Co Ltd | マイクロチップ |
WO2003011768A2 (en) * | 2001-08-01 | 2003-02-13 | Datascope Investment Corp. | Microfluidic device for molecular analysis |
US7338760B2 (en) * | 2001-10-26 | 2008-03-04 | Ntu Ventures Private Limited | Sample preparation integrated chip |
EP1546412B1 (de) * | 2002-10-02 | 2014-05-21 | California Institute Of Technology | MIKROFLUIDISCHE NUKLEINSûUREANALYSE |
US20040086872A1 (en) * | 2002-10-31 | 2004-05-06 | Childers Winthrop D. | Microfluidic system for analysis of nucleic acids |
CA3171720C (en) * | 2002-12-26 | 2024-01-09 | Meso Scale Technologies, Llc. | Methods for conducting electrochemiluminescence measurements |
DE10319045A1 (de) * | 2003-04-25 | 2004-12-09 | november Aktiengesellschaft Gesellschaft für Molekulare Medizin | Vorrichtung und Verfahren zur Aufbereitung Biopolymerhaltiger Flüssigkeiten |
JP4455014B2 (ja) * | 2003-11-07 | 2010-04-21 | セイコーインスツル株式会社 | 検査用マイクロチップおよび検査装置と検査方法 |
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2004
- 2004-01-28 GB GB0401868A patent/GB2416030B/en not_active Expired - Fee Related
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2005
- 2005-01-28 US US10/597,541 patent/US20080227185A1/en not_active Abandoned
- 2005-01-28 MX MXPA06008469A patent/MXPA06008469A/es not_active Application Discontinuation
- 2005-01-28 BR BRPI0507200-0A patent/BRPI0507200A/pt not_active IP Right Cessation
- 2005-01-28 KR KR1020067017188A patent/KR20070027507A/ko not_active Application Discontinuation
- 2005-01-28 CN CN200580006519.XA patent/CN1973197B/zh not_active Expired - Fee Related
- 2005-01-28 DE DE602005020742T patent/DE602005020742D1/de active Active
- 2005-01-28 WO PCT/GB2005/000308 patent/WO2005073691A1/en active Search and Examination
- 2005-01-28 AU AU2005208085A patent/AU2005208085B8/en not_active Ceased
- 2005-01-28 CA CA002554452A patent/CA2554452A1/en not_active Abandoned
- 2005-01-28 NZ NZ548801A patent/NZ548801A/en unknown
- 2005-01-28 JP JP2006550304A patent/JP4921177B2/ja not_active Expired - Fee Related
- 2005-01-28 AT AT05702057T patent/ATE465401T1/de not_active IP Right Cessation
- 2005-01-28 EA EA200601377A patent/EA011753B1/ru not_active IP Right Cessation
- 2005-01-28 EP EP05702057A patent/EP1714134B1/de not_active Not-in-force
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2006
- 2006-07-26 ZA ZA200606197A patent/ZA200606197B/en unknown
- 2006-07-27 IL IL177122A patent/IL177122A/en not_active IP Right Cessation
- 2006-08-24 NO NO20063782A patent/NO20063782L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU2005208085B8 (en) | 2011-02-24 |
KR20070027507A (ko) | 2007-03-09 |
GB2416030B (en) | 2008-07-23 |
CN1973197B (zh) | 2010-12-15 |
EP1714134B1 (de) | 2010-04-21 |
WO2005073691A1 (en) | 2005-08-11 |
GB0401868D0 (en) | 2004-03-03 |
MXPA06008469A (es) | 2009-03-11 |
JP2007519917A (ja) | 2007-07-19 |
CN1973197A (zh) | 2007-05-30 |
BRPI0507200A (pt) | 2007-06-12 |
US20080227185A1 (en) | 2008-09-18 |
GB2416030A (en) | 2006-01-11 |
IL177122A0 (en) | 2006-12-10 |
IL177122A (en) | 2011-07-31 |
EA011753B1 (ru) | 2009-06-30 |
AU2005208085B2 (en) | 2010-12-16 |
EP1714134A1 (de) | 2006-10-25 |
NO20063782L (no) | 2006-10-19 |
ATE465401T1 (de) | 2010-05-15 |
EA200601377A1 (ru) | 2007-02-27 |
CA2554452A1 (en) | 2005-08-11 |
AU2005208085A1 (en) | 2005-08-11 |
JP4921177B2 (ja) | 2012-04-25 |
NZ548801A (en) | 2010-12-24 |
ZA200606197B (en) | 2008-02-27 |
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