DE602005005449D1 - Adjuvante zusammensetzungen - Google Patents
Adjuvante zusammensetzungenInfo
- Publication number
- DE602005005449D1 DE602005005449D1 DE602005005449T DE602005005449T DE602005005449D1 DE 602005005449 D1 DE602005005449 D1 DE 602005005449D1 DE 602005005449 T DE602005005449 T DE 602005005449T DE 602005005449 T DE602005005449 T DE 602005005449T DE 602005005449 D1 DE602005005449 D1 DE 602005005449D1
- Authority
- DE
- Germany
- Prior art keywords
- adjuvant
- protein
- carbohydrate
- extracts
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000002671 adjuvant Substances 0.000 title abstract 7
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000000284 extract Substances 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 230000002238 attenuated effect Effects 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 229920001282 polysaccharide Polymers 0.000 abstract 2
- 239000005017 polysaccharide Substances 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 230000003612 virological effect Effects 0.000 abstract 2
- HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical compound O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 abstract 1
- 229930186217 Glycolipid Natural products 0.000 abstract 1
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 229930013930 alkaloid Natural products 0.000 abstract 1
- 150000003797 alkaloid derivatives Chemical class 0.000 abstract 1
- 239000013566 allergen Substances 0.000 abstract 1
- 229940037003 alum Drugs 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 230000003278 mimic effect Effects 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- -1 polysaccharides carbohydrate Chemical class 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 210000000605 viral structure Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/208—IL-12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0401239 | 2004-01-21 | ||
| GBGB0401239.9A GB0401239D0 (en) | 2004-01-21 | 2004-01-21 | Adjuvant compositions |
| PCT/GB2005/000228 WO2005070415A1 (en) | 2004-01-21 | 2005-01-21 | Adjuvant compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE602005005449D1 true DE602005005449D1 (de) | 2008-04-30 |
| DE602005005449T2 DE602005005449T2 (de) | 2009-08-27 |
Family
ID=31971168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602005005449T Active DE602005005449T2 (de) | 2004-01-21 | 2005-01-21 | Adjuvante zusammensetzungen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090047306A1 (de) |
| EP (1) | EP1711174B1 (de) |
| AT (1) | ATE389397T1 (de) |
| AU (1) | AU2005205968C1 (de) |
| CA (1) | CA2553986A1 (de) |
| DE (1) | DE602005005449T2 (de) |
| GB (1) | GB0401239D0 (de) |
| WO (1) | WO2005070415A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE315405T1 (de) * | 1998-08-10 | 2006-02-15 | Antigenics Inc | Cpg-zusammensetzungen, saponin-adjuvantien und verfahren zu deren verwendung |
| US8221761B1 (en) * | 1999-02-26 | 2012-07-17 | Novartis Ag | Enhancement of bactericidal activity of neisseria antigens with oligonucleotides containing CG motifs |
| GB0401238D0 (en) * | 2004-01-21 | 2004-02-25 | Molecularnature Ltd | Immunomodulatory alkaloids |
| JP5265545B2 (ja) * | 2006-09-01 | 2013-08-14 | シーエスエル、リミテッド | 免疫応答を誘発または誘導する方法 |
| EP2198030B1 (de) * | 2007-10-10 | 2016-09-14 | Athenix Corporation | Für cry1ac kodierende synthetische gene |
| CN101820904A (zh) | 2007-10-12 | 2010-09-01 | Csl有限公司 | 引起针对大流行性流感病毒的免疫应答的方法 |
| KR20180056778A (ko) * | 2015-10-08 | 2018-05-29 | 온코세라피 사이언스 가부시키가이샤 | Foxm1 유래 펩티드 및 이를 포함하는 백신 |
| IL286493B (en) | 2015-11-06 | 2022-07-01 | Memorial Sloan Kettering Cancer Center | Triterpene saponin analogs, methods for their production, preparations containing them and their uses |
| KR20190137827A (ko) * | 2017-04-25 | 2019-12-11 | 아쥬반스 테크놀로지스 인코포레이티드 | 트리테르펜 사포닌 유사체 |
| KR20200098476A (ko) | 2017-10-16 | 2020-08-20 | 아쥬반스 테크놀로지스 인코포레이티드 | 트리테르펜 사포닌 유사체 |
| IL308638A (en) * | 2021-05-18 | 2024-01-01 | Attias Eyal | Use of erythropoietin or a substance that encourages erythropoiesis, to treat osteomyelitis and bone infection |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0301554D0 (en) * | 2003-01-23 | 2003-02-26 | Molecularnature Ltd | Immunostimulatory compositions |
-
2004
- 2004-01-21 GB GBGB0401239.9A patent/GB0401239D0/en not_active Ceased
-
2005
- 2005-01-21 CA CA002553986A patent/CA2553986A1/en not_active Abandoned
- 2005-01-21 EP EP05701990A patent/EP1711174B1/de active Active
- 2005-01-21 US US10/597,296 patent/US20090047306A1/en not_active Abandoned
- 2005-01-21 DE DE602005005449T patent/DE602005005449T2/de active Active
- 2005-01-21 WO PCT/GB2005/000228 patent/WO2005070415A1/en active Application Filing
- 2005-01-21 AT AT05701990T patent/ATE389397T1/de not_active IP Right Cessation
- 2005-01-21 AU AU2005205968A patent/AU2005205968C1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ATE389397T1 (de) | 2008-04-15 |
| AU2005205968C1 (en) | 2010-12-02 |
| AU2005205968A1 (en) | 2005-08-04 |
| DE602005005449T2 (de) | 2009-08-27 |
| US20090047306A1 (en) | 2009-02-19 |
| EP1711174B1 (de) | 2008-03-19 |
| CA2553986A1 (en) | 2005-08-04 |
| WO2005070415A1 (en) | 2005-08-04 |
| EP1711174A1 (de) | 2006-10-18 |
| AU2005205968B2 (en) | 2010-07-29 |
| GB0401239D0 (en) | 2004-02-25 |
| AU2005205968B8 (en) | 2010-08-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |