DE602004024549D1 - Diagnose und überwachung von hepatozellulärem karzinom - Google Patents

Diagnose und überwachung von hepatozellulärem karzinom

Info

Publication number
DE602004024549D1
DE602004024549D1 DE602004024549T DE602004024549T DE602004024549D1 DE 602004024549 D1 DE602004024549 D1 DE 602004024549D1 DE 602004024549 T DE602004024549 T DE 602004024549T DE 602004024549 T DE602004024549 T DE 602004024549T DE 602004024549 D1 DE602004024549 D1 DE 602004024549D1
Authority
DE
Germany
Prior art keywords
hepatocellular carcinoma
diagnosis
monitoring
sera
onset
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004024549T
Other languages
German (de)
English (en)
Inventor
Patrick R Romano
Timothy M Block
Claus J Fimmel
Olga Nikolaeva
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thomas Jefferson University
St Louis University
US Department of Veterans Affairs
Original Assignee
Thomas Jefferson University
St Louis University
US Department of Veterans Affairs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas Jefferson University, St Louis University, US Department of Veterans Affairs filed Critical Thomas Jefferson University
Publication of DE602004024549D1 publication Critical patent/DE602004024549D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57525—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the liver or pancreas

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE602004024549T 2003-09-05 2004-09-03 Diagnose und überwachung von hepatozellulärem karzinom Expired - Lifetime DE602004024549D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50065703P 2003-09-05 2003-09-05
PCT/US2004/028766 WO2005026687A2 (en) 2003-09-05 2004-09-03 Diagnosis and monitoring of hepatocellular carcinoma

Publications (1)

Publication Number Publication Date
DE602004024549D1 true DE602004024549D1 (de) 2010-01-21

Family

ID=34312211

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004024549T Expired - Lifetime DE602004024549D1 (de) 2003-09-05 2004-09-03 Diagnose und überwachung von hepatozellulärem karzinom

Country Status (7)

Country Link
US (1) US20050112711A1 (https=)
EP (1) EP1664718B1 (https=)
JP (1) JP4574619B2 (https=)
AT (1) ATE451477T1 (https=)
DE (1) DE602004024549D1 (https=)
ES (1) ES2337791T3 (https=)
WO (1) WO2005026687A2 (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9957569B2 (en) * 2005-09-12 2018-05-01 The Regents Of The University Of Michigan Recurrent gene fusions in prostate cancer
CA2814598A1 (en) 2005-09-12 2007-03-22 The Regents Of The University Of Michigan Recurrent gene fusions in prostate cancer
WO2008021163A2 (en) * 2006-08-09 2008-02-21 Saint Louis University Kits and methods for determining risk for primary liver cancer
WO2008060394A2 (en) * 2006-10-27 2008-05-22 Inova Diagnostics, Inc. Methods and assays for detecting gp73-specific autoantibodies
CA2668961A1 (en) * 2006-11-08 2008-05-15 The Regents Of The University Of Michigan Spink1 as a prostate cancer marker and uses thereof
ES2376509T3 (es) * 2007-07-06 2012-03-14 The Regents Of The University Of Michigan Reordenamientos de genes mipol 1-etv1.
CN101988926A (zh) * 2009-08-03 2011-03-23 中国科学院广州生物医药与健康研究院 一种高尔基蛋白gp73的夹心elisa定量检测方法及其检测试剂盒
CN102712953A (zh) * 2009-09-17 2012-10-03 密歇根大学董事会 前列腺癌中的复发性基因融合物
US8945556B2 (en) 2010-11-19 2015-02-03 The Regents Of The University Of Michigan RAF gene fusions
CN102854324B (zh) * 2012-08-17 2014-10-22 西北大学 快速无损伤性检测肝肿瘤标志物的方法以及采用的试纸条
US9469686B2 (en) 2013-03-15 2016-10-18 Abbott Laboratories Anti-GP73 monoclonal antibodies and methods of obtaining the same
CN104215761B (zh) * 2014-08-27 2016-04-20 广西医科大学 检测血清中抗gp73抗体的试剂盒
CN105699653B (zh) * 2014-11-25 2017-08-25 北京市肝病研究所 一种超敏感超顺磁性纳米免疫微球及其检测gp73抗原的方法
CN104360080B (zh) * 2014-12-05 2016-03-02 重庆乾德生物技术有限公司 一种高尔基体糖蛋白-73检测试剂盒
CN107345967A (zh) * 2016-05-05 2017-11-14 中国医学科学院基础医学研究所 Gp73蛋白作为血清标记物在诊断癌症中的用途
CN106405104B (zh) * 2016-08-31 2019-01-08 鲁凤民 一种新的肝硬化或肝纤维化标志物
CN107247148B (zh) * 2017-04-27 2020-03-27 鲁凤民 Gp73的新用途及一种基于其的肝组织炎症活动度检测试剂盒
WO2019068695A1 (en) * 2017-10-02 2019-04-11 Universität Zu Köln TUMOR AND METASTASIS MARKER
CN107746430B (zh) * 2017-10-19 2021-03-23 天津金虹生物科技开发有限公司 一种gp73 c端抗原的制备及其应用
CN115754290A (zh) * 2022-09-26 2023-03-07 浙江大学 一种用于检测早期肝癌的试剂盒

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733738A (en) * 1983-08-17 1998-03-31 Ligand Pharmaceuticals Polypeptide-induced monoclonal receptors to protein ligands
DE10136273A1 (de) * 2001-07-25 2003-02-13 Sabine Debuschewitz Molekulare Marker beim hepatozellulären Karzinom
US7229774B2 (en) * 2001-08-02 2007-06-12 Regents Of The University Of Michigan Expression profile of prostate cancer
WO2008060394A2 (en) * 2006-10-27 2008-05-22 Inova Diagnostics, Inc. Methods and assays for detecting gp73-specific autoantibodies

Also Published As

Publication number Publication date
EP1664718A2 (en) 2006-06-07
EP1664718A4 (en) 2007-09-19
JP2007506945A (ja) 2007-03-22
WO2005026687A3 (en) 2006-06-22
JP4574619B2 (ja) 2010-11-04
US20050112711A1 (en) 2005-05-26
WO2005026687A2 (en) 2005-03-24
ATE451477T1 (de) 2009-12-15
ES2337791T3 (es) 2010-04-29
EP1664718B1 (en) 2009-12-09

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