DE60142187D1 - Verfahren und zusammensetzung zur behandlung von trockenen augen - Google Patents

Verfahren und zusammensetzung zur behandlung von trockenen augen

Info

Publication number
DE60142187D1
DE60142187D1 DE60142187T DE60142187T DE60142187D1 DE 60142187 D1 DE60142187 D1 DE 60142187D1 DE 60142187 T DE60142187 T DE 60142187T DE 60142187 T DE60142187 T DE 60142187T DE 60142187 D1 DE60142187 D1 DE 60142187D1
Authority
DE
Germany
Prior art keywords
film
eye
composition
mixture
emulsion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60142187T
Other languages
English (en)
Inventor
Simon Benita
Gregory Lambert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novagali SA
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Novagali SA
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novagali SA, Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Novagali SA
Application granted granted Critical
Publication of DE60142187D1 publication Critical patent/DE60142187D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions
DE60142187T 2001-11-01 2001-11-01 Verfahren und zusammensetzung zur behandlung von trockenen augen Expired - Lifetime DE60142187D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IL2001/001015 WO2003053405A1 (en) 2001-11-01 2001-11-01 Method and composition for dry eye treatment

Publications (1)

Publication Number Publication Date
DE60142187D1 true DE60142187D1 (de) 2010-07-01

Family

ID=11043109

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60142187T Expired - Lifetime DE60142187D1 (de) 2001-11-01 2001-11-01 Verfahren und zusammensetzung zur behandlung von trockenen augen

Country Status (11)

Country Link
EP (1) EP1441696B1 (de)
JP (1) JP2005513097A (de)
CN (1) CN100335036C (de)
AT (1) ATE468107T1 (de)
AU (1) AU2002214233A1 (de)
CA (1) CA2464243C (de)
DE (1) DE60142187D1 (de)
ES (1) ES2343512T3 (de)
HK (1) HK1067316A1 (de)
IL (1) IL161588A0 (de)
WO (1) WO2003053405A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
DE602004022523D1 (de) * 2004-07-02 2009-09-24 Novagali Pharma Sa Verwendung von Emulsionen zur intra- und periocularen Injection
WO2006003519A2 (en) * 2004-07-02 2006-01-12 Novagali Pharma Sa Use of emulsions for intra: and periocular injection
WO2006009112A1 (ja) * 2004-07-16 2006-01-26 Taisho Pharmaceutical Co., Ltd. 水性点眼剤
EP1655021B1 (de) * 2004-11-09 2008-10-29 Novagali Pharma SA Öl-in-Wasser-Emulsion mit niedriger Konzentration des kationischen Mittels und positivem Zetapotential
AU2005304034B2 (en) * 2004-11-09 2012-02-16 Santen Sas Ophthalmic emulsions containing an immunosuppressive agent
PL1885336T3 (pl) * 2005-05-10 2009-08-31 Alcon Inc Kompozycja w postaci zawiesiny zawierająca substancję aktywną, poloksamerowy lub meroksapolowy surfaktant i glikol oraz zastosowanie kompozycji do wytwarzania leku do leczenia chorób oczu
US7288520B2 (en) * 2005-07-13 2007-10-30 Allergan, Inc. Cyclosporin compositions
US8288348B2 (en) 2005-07-13 2012-10-16 Allergan, Inc. Cyclosporin compositions
JP5247453B2 (ja) 2005-10-10 2013-07-24 ノバガリ ファルマ エスア プロスタグランジン含有眼科用カチオン性水中油型エマルジョン
US10137083B2 (en) 2006-03-07 2018-11-27 SGN Nanopharma Inc Ophthalmic preparations
US11311477B2 (en) 2006-03-07 2022-04-26 Sgn Nanopharma Inc. Ophthalmic preparations
ES2369244T3 (es) * 2006-03-13 2011-11-28 Advancell Advanced In Vitro Cell Technologies,S.A. Sistemas estables de nanocápsulas para la administración de moléculas activas.
US20070280902A1 (en) 2006-06-01 2007-12-06 Laura Rabinovich-Guilatt Method for treating eye disease or conditions affecting the posterior segment of the eye
WO2008035246A2 (en) 2006-07-28 2008-03-27 Novagali Pharma Sa Compositions containing quaternary ammonium compounds
CN101130058B (zh) * 2006-08-23 2011-10-05 华北制药集团新药研究开发有限责任公司 一种环孢菌素a眼用乳剂及其制备方法
WO2008120249A1 (en) 2007-03-30 2008-10-09 Sifi S.P.A. Pharmaceutical formulations based on apolar and polar lipids for ophthalmic use
EP2228058A1 (de) 2009-03-04 2010-09-15 Novagali Pharma S.A. Anionische Öl-in-Wasser-Emulsion mit Prostaglandinen und Verwendungen dafür
EP2308468A1 (de) * 2009-10-08 2011-04-13 Novaliq GmbH Neuartige pharmazeutische Zusammensetzung mit einem Makrolid-Immunosuppressivum
EP2389939A1 (de) 2010-05-28 2011-11-30 Novagali Pharma S.A. Verwendung von Prostaglandinen F2alpha und Analoga zur Heilung von Horn- und Bindehautläsionen
ES2797376T3 (es) 2013-01-24 2020-12-02 Palvella Therapeutics Inc Composiciones para la administración transdérmica de inhibidores de mTOR
CN110520097B (zh) 2017-01-06 2023-10-27 帕尔维拉治疗股份有限公司 Mtor抑制剂的无水组合物及其使用方法
WO2020010073A1 (en) 2018-07-02 2020-01-09 Palvella Therapeutics, Inc. ANHYDROUS COMPOSITIONS OF mTOR INHIBITORS AND METHODS OF USE
CN109010270B (zh) * 2018-09-03 2021-07-30 辅必成(上海)医药科技有限公司 一种阳离子材料制备的眼用乳

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL101241A (en) * 1992-03-16 1997-11-20 Yissum Res Dev Co Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier
ZA966579B (en) * 1995-08-04 1998-02-02 Wakamoto Pharma Co Ltd O/W emulsion composition for eye drops.
DE10036871A1 (de) * 2000-07-28 2002-02-14 Pharmasol Gmbh Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe

Also Published As

Publication number Publication date
ES2343512T3 (es) 2010-08-03
WO2003053405A1 (en) 2003-07-03
CA2464243C (en) 2010-01-19
JP2005513097A (ja) 2005-05-12
CN100335036C (zh) 2007-09-05
EP1441696B1 (de) 2010-05-19
AU2002214233A1 (en) 2003-07-09
CA2464243A1 (en) 2003-07-03
IL161588A0 (en) 2004-09-27
ATE468107T1 (de) 2010-06-15
HK1067316A1 (en) 2005-04-08
CN1558751A (zh) 2004-12-29
EP1441696A1 (de) 2004-08-04

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Legal Events

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8364 No opposition during term of opposition