DE60105973T2 - Hemostatic valve - Google Patents

Hemostatic valve

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Publication number
DE60105973T2
DE60105973T2 DE2001605973 DE60105973T DE60105973T2 DE 60105973 T2 DE60105973 T2 DE 60105973T2 DE 2001605973 DE2001605973 DE 2001605973 DE 60105973 T DE60105973 T DE 60105973T DE 60105973 T2 DE60105973 T2 DE 60105973T2
Authority
DE
Germany
Prior art keywords
valve
hemostatic
valve seal
seal
proximal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE2001605973
Other languages
German (de)
Other versions
DE60105973D1 (en
Inventor
Xiaoping Guo
J. Daniel POTTER
Richard Stehr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
St Jude Medical Atrial Fibrillation Division Inc
Original Assignee
Daig Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US491221 priority Critical
Priority to US09/491,221 priority patent/US6551283B1/en
Priority to US734391 priority
Priority to US09/734,391 priority patent/US6632200B2/en
Application filed by Daig Corp filed Critical Daig Corp
Priority to PCT/US2001/001588 priority patent/WO2001054763A2/en
Publication of DE60105973D1 publication Critical patent/DE60105973D1/en
Application granted granted Critical
Publication of DE60105973T2 publication Critical patent/DE60105973T2/en
Application status is Active legal-status Critical
Anticipated expiration legal-status Critical

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02Access sites
    • A61M39/06Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02Access sites
    • A61M39/06Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
    • A61M2039/0633Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof the seal being a passive seal made of a resilient material with or without an opening
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02Access sites
    • A61M39/06Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
    • A61M2039/0633Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof the seal being a passive seal made of a resilient material with or without an opening
    • A61M2039/064Slit-valve
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02Access sites
    • A61M39/06Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
    • A61M2039/0633Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof the seal being a passive seal made of a resilient material with or without an opening
    • A61M2039/0653Perforated disc
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02Access sites
    • A61M39/06Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
    • A61M2039/0686Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof comprising more than one seal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02Access sites
    • A61M39/06Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof
    • A61M39/0606Haemostasis valves, i.e. gaskets sealing around a needle, catheter or the like, closing on removal thereof without means for adjusting the seal opening or pressure

Description

  • AREA OF INVENTION
  • The The present invention relates to medical devices and devices. Especially The present invention relates to hemostasis valves and hemostasis Cannula units the one hemostatic Valve containing the hemostatic valve consists of two separate valve seals, which are the same Have shape and arranged in the opposite direction to each other are but in the valve body the hemostatic cannula unit are connected.
  • STATE OF TECHNOLOGY
  • The introduction of catheters in blood vessels has been around many years for a large number of examinations, for example for coronary angiography, known. For the introduction the catheter into the vascular system of the human body There are several methods available. One such method is the cut-down method, another one Seldinger technique. When Seldinger method is a vein or Artery surgically opened by a needle through the lumen of the Needle a guidewire introduced into the vessel, the Needle pulled back, over the guidewire introduced a dilator, the previously by a hemostatic Valve-containing shell was pushed, the dilator removed and a catheter through the Case with the hemostatic Valve inserted into the blood vessel.
  • in the The state of the art is a big one Variety of hemostatic Valves known. At the introduction a guidewire through most hemostatic Valves it is due to the relatively low Size of guidewires in comparison often difficult to adequately seal the catheters also used through the valve to reach against the blood pressure, if at the same time a light introduction of catheters of much larger diameter into the vascular system to be held. This problem is especially common in catheterization procedures with arterial introduction because of high blood pressure. For arterial surgery it happens often to jetting out of blood when the guidewire passes through the hemostatic Valve introduced becomes. High blood loss can for very dangerous to the patient and also means contamination for the operating room and the medical staff. Accordingly, most are in the state the art known haemostatic Valves designed for use with one catheter size only. Frequently It's difficult with a single type of hemostatic valve catheter to use with very different diameters, as by these hemostatic Valves no adequate Sealing around the catheter walls is reached.
  • Cardiac catheter introducers used in heart surgery often include a hemostatic valve mounted in a valve housing or valve port attached to the proximal end of the introducer. These introducers are commonly used to facilitate insertion of catheters and guidewires into a patient's vasculature while minimizing trauma to the patient at the point of entry and improving patient comfort during cardiac catheterization. An introducer device is particularly necessary when one or more different diameter treatment catheters are repeatedly inserted and withdrawn into the patient's vessel, as is common in angiographic procedures and angioplasty. The mere presence of the introducer for the catheter and the introduction of different sized catheters through the introducer often causes bleeding during cardiac catheterization. For these reasons, a powerful hemostatic valve is needed to provide a seal against leakage of blood on or around the catheters and guidewires of different diameters as they enter an artery or other blood vessel. The hemostasis valve must also prevent air from entering the artery or blood vessel of the patient when retracting one or more of the elongated catheters or guide wires from the introducer device. Additionally, the valve must also be leak tight when there is no medical device in the valve. Accordingly, the requirements for a useful hemostatic valve include at least the following: (a) the valve is always sealed when no elongate cylindrical medical device is being performed; (b) the insertion and withdrawal forces must be minimal when larger catheters (for example greater than 9 F (3 mm)) are inserted into the valve; ( 3 ) in contrast, the valve must have good sealing properties when small diameter guide wires (up to 0.014 inches (0.35 mm) are passed through its passageway; and (4) valve deformation should be as far as possible only in the radial direction and not in the axial direction to prevent the transfer of air into the bloodstream.
  • There are numerous hemostatic valves known, which can be assigned to three main types. Type I is disclosed, for example, in U.S. Patents 5,041,095 and 5,176,652 and includes a pair of disc-shaped seals of approximately equal thickness. In each seal is a Y-shaped opening extending radially from the center of he stretches and out of three ( 3 ) Slots, each slot having an angle of about 120 degrees to the other slots. Each slot leads from one end face of the valve to the other end face. In order to form a self-sealing valve, the two Y-shaped slots of the respective seals are arranged in opposite directions in the valve housing.
  • Other Types of hemostatic Valves that contain multiple discs that are about the same size and thickness are disclosed, for example, in U.S. Patents 2,023,267; 4,000,739; 4,430,081; 4,655,752; 4,673,393; 4,895,346; 5,000,745 and 5,643,227. Each of these patents discloses a different combination of disc valves leading to the formation of the hemostatic Valve be used. In some embodiments, one includes the discs are Y-shaped Slots and the other disc has a circular opening in the middle of this disc.
  • The DE 297 01 600 discloses a hemostatic valve with two discs, each disc ( 1 . 11 ) a pair of protrusions ( 3 . 3 ' ) extending outwardly from the surface of the disk and a pair of slots (FIG. 4 . 4 ' ). The projections ( 3 . 3 ' ) do not extend down to the slots ( 4 . 4 ' ) of the complementary disk ( 1' ).
  • Type II hemostatic valves are described, for example, in US Pat. Nos. 4,626,245; 4,629,450; 5,114,408; 5,149,327 and 5,167,637 disclose and use a single sealing washer. This disc essentially has a first slot which opens only to one end face and a second slot which opens only to the other end face. The two slots form a cross and overlap in the disk. Other types of hemostatic valves with a valve and different shapes of opening through the disc are described, for example, in US Pat. Nos. 4,705,511 (see 4 ); 4,798,594 and 4,895,565.
  • hemostatic Type III valves, similar like hemostatic Type II valves are disclosed, for example, in U.S. Patents 5,149,327; 5,207,656 and 5,520,655 disclose and differ in that only one slot (Y-shaped or + -shaped) itself from an end face of the valve to the other end surface extends. The slot can be perpendicular to the body of the valve his or he can be spiraling be formed to a downwardly extending spiral slot as described in U.S. Patents 5,520,655; 4,789,594 and 4,895,565 is disclosed. It is particularly to US Patent 4,705,511 noted that a hemostatic Valve with an angular slot, which extends from the proximal to the distal side disclosed.
  • Other Types hemostatic Valves are disclosed in various patents, such as U.S. Patents 4,610,655; 4,909,798 and 5,125,903. However, these hemostatic valves are generally for use with a particular size of medical device certainly.
  • There an adequate one Caulking for oblong cylindrical medical devices using conventional hemostatic Valves not for a variety of devices, each of which has a different Diameter has, can be ensured, is the use a single hemostatic Valve for Devices with very different diameters not possible. In addition, show many of the hemostatic valves of the prior art different performance defects, which are due to different structural properties. For example, it can be difficult to get an elongated cylindrical medical Device through a self-closing slots formed passage to manipulate, since no central management channel provided is. additionally Hemostatic deforms Type I valves through the introduction the elongated one cylindrical medical device into the valve substantially in the axial direction and not radially outward from the opening. In these hemostatic Valves will be replaced by the introduction of a medical device an axial gap between the seals formed, which under high blood pressure to a leakage of blood to lead can. In hemostatic Type II valves sometimes diminish these axial gaps by the sealing functions of two seals in a single Seal to be integrated. Through this integration, the Seal compared to hemostatic Type I valves to be improved. The introduction of medical devices through the passage of the valves necessary insertion is however greatly increased, because the deforming force of the two slits of the hemostatic Opposite valve is and the friction is at the interface of the two slots increased within the valve.
  • at hemostatic Type III valves can also be a problem with the insertion force represent. Furthermore These valves often seal not against leakage of blood when a guidewire of small diameter through the slit-shaped passage is pushed. additionally can the retreat, when retiring of larger diameter catheters is generated, causing air to enter the bloodstream.
  • As is known, the axial deformati be limited on the hemostatic valve to improve the seal. For example, U.S. Patent 5,520,655 discloses a medical device in which the valve is biased in the axial direction against the insertion force. This bias compensates for the axial deformation caused by the insertion of an elongate medical device. The actual deformation during insertion therefore acts radially to the valve, thereby improving the seal of the valve. However, the insertion force may be increased due to this bias, and the retraction force on removal of the elongate cylindrical device may still allow air to enter the bloodstream.
  • The U.S. Patent 4,917,668 suggests the use of spring-loaded elastic seal valve parts before, wherein one or more spring elements, the natural elasticity of the sealing material support, to improve the seal. The insertion force is, however, by the Use of metal springs increased.
  • at another approach, among various occurring in practice Conditions to achieve a suitable seal is disclosed in US Pat 5,125,903 proposed the use of concave and convex curved surfaces, around the thin one form the central region of the valve, through which the short extending intersecting slots at an angle of 45 degrees to the line, which is arranged at an angle of 90 degrees to the intersection.
  • The haemostatic described above Valves should be the defects the flat disk-shaped Improve seals and include holes of reduced diameter, Slots and intersecting slits to elongated cylindrical medical Devices to be pushed through the valve to be able to record. However, there are still further improvements to valves for sealing of blood flow necessary to overcome known problems with valves of the State of the art remedy.
  • Of the The present invention was therefore based on a universal task haemostatic valve to provide that high performance in sealing against Blood leakage has limited the return of air to the vessels and the introduction and retreating of oblong cylindrical medical devices of different diameters facilitated. This hemostatic Valve can be reliable with a variety of both large catheters up to about 9 F (3mm) and small guidewires up down to 0.014 inches (0.35 mm).
  • One Another object of the invention is the disclosure of a hemostatic Valve, consisting of two separate valve seals, with are formed of the same shape and which are connected to the hemostatic To form valve.
  • One Another object of the invention is the disclosure of a hemostatic Valve, comprising a proximal valve seal and a distal Valve seal, wherein each of the valve seals at least one Positioning groove and has at least one positioning projection, which interact with each other to make the two seals in one certain position relative to each other to arrange.
  • One Another object of the invention is the disclosure of a hemostatic Valve, comprising a pair of valve seals, the middle each valve seal in relation to the total thickness of the valve seal very thin is trained.
  • One Another object of the invention is the disclosure of a hemostatic Valve, comprising a pair of valve seals, each of which a slot, each slot at an angle of 85 degrees to about 30 degrees to the position of the surface of each Valve seal is angled.
  • One Another object of the invention is the disclosure of a hemostatic Valve, comprising a pair of valve seals, each one conical receiving area and a guide hole includes to medical Devices through the hemostatic To lead valve.
  • One Another object of the invention is the disclosure of a hemostatic Valve, comprising a pair of valve seals, each of which a beveled Edge, which extends in the direction of the valve housing, when a medical device is inserted into the hemostasis valve.
  • One Another object of the invention is the disclosure of a hemostatic Valve, comprising a pair of valve seals in contact stay together when a medical device passes through the hemostatic Valve guided becomes.
  • One Another object of the invention is the disclosure of a hemostatic Valve, comprising a pair of identical, interconnected Valve seals, wherein the input surface of the proximal valve seal and the exit area the distal valve seal axially compressible concentric rings exhibit.
  • Another object of the invention is the disclosure of a hemostatic cannula unit comprising a valve housing, a cap and a hemos tatic valve, wherein the hemostatic valve comprises a pair of identical valve seals, each containing at least one positioning groove and at least one positioning projection, which interact with each other to arrange the two seals in a certain position relative to each other.
  • These and other objects are achieved with the disclosed hemostatic valve and the hemostatic cannula unit achieved, which are described in the present disclosure.
  • SUMMARY THE INVENTION
  • The present invention comprises a hemostatic cannula unit, comprising a longitudinal direction extending housing, that on opposite Ends a first opening and a second opening has a cap which closes the first end and the an opening contains to the introduction a dilator or catheter into the longitudinally extending housing, and a hemostatic Valve consisting of a pair of identical valve seals, the through the valve body be pressed against each other.
  • The The invention also includes a hemostatic Valve comprising two separate, identical valve seals, wherein the proximal valve seal through at least one positioning groove and a positioning projection provided in each valve gasket are, and which interact with each other, relative to the distal Valve seal is held in a certain position.
  • The The invention also relates to a haemostatic Valve comprising two separate but identical valve seals, the center of each valve seal compared to the total thickness the valve seal is very thin is.
  • The The invention also includes a hemostatic Valve comprising two separate but identical valve seals, each having a slot, each slot at an angle from about 30 degrees to about 85 degrees to the front of the valve seal is angled.
  • The The invention also relates to a haemostatic Valve comprising two separate but identical valve seals, each of which has a conical receiving area and each of which a centering or pilot hole having.
  • The The invention also relates to a haemostatic Valve comprising two separate but identical valve seals, the entrance area the proximal valve seal and the output surface of the distal valve seal each having concentric rings different from the respective ones surfaces extend the two valve seals, these concentric Rings are compressed when the hemostatic valve is placed in a hemostasis valve housing becomes.
  • The The invention also relates to a haemostatic Valve comprising two separate but identical valve seals, the sides of each of the hemostatic Valve seals a bevelled edge have, which extend in the direction of the inner wall of the valve housing, when a medical device is inserted into the hemostasis valve.
  • The The invention also relates to a haemostatic Valve comprising two separate but identical valve seals, the distal surface the proximal valve seal and the proximal surface of the distal valve seal stay in contact with each other when a medical device is inserted into the hemostasis valve.
  • The The invention also includes a hemostatic Valve comprising two separate valve seals, each of which having an angled slot, wherein the angled slot in the proximal seal with a proximal surface of the distal Seal cooperates and the angled slot in the distal Seal with the distal surface the proximal seal cooperates to help remove a medical Instruments from the valve to effect a sealing of the same.
  • SHORT DESCRIPTION THE DRAWINGS
  • 1 shows a view of a cross section through the hemostatic valve according to the invention, which is arranged in a hemostatic cannula unit.
  • 2 shows an exploded view of the hemostatic cannula unit of 1 and shows its components, including the proximal and distal seals of the hemostatic valve.
  • 3 shows a perspective view of the hemostatic valve from distal and shows how the proximal and distal valve seals are connected.
  • 4 shows a perspective view of the proximal valve seal from proximal with an acute-angled slot.
  • 5 shows a perspective view of the proximal valve seal of the hemostasis valve from distal.
  • 5A shows a side view of the proxi paint valve seal 5 with an acute-angled slot.
  • 5B shows a side view of the proximal valve seal 5 with a rectangular slot.
  • 6 shows a view from distal to the distal valve seal of the hemostatic valve with an acute-angled slot.
  • 6B shows a side view of a partially cut distal valve seal 6 and shows the thickness ( 60 ) of the slot, the thickness ( 62 ) of the slot and the guide hole and the thickness ( 64 ) of the valve seal between the inlet and outlet surface.
  • 7 shows a view from proximal to the distal valve seal 6 ,
  • 8th Figure 11 is a top view of a cutaway view of the hemostatic valve showing how a medical device is inserted in cross-section.
  • 9 shows a distal view of a partially cutaway enlarged section of the hemostasis valve 3 and shows how the cuts of the angled slots extend through the respective seals.
  • 10 shows a side view of a partially cut hemostatic cannula unit 1 where a medical device is inserted in the unit.
  • LONG DESCRIPTION THE INVENTION
  • The powerful haemostatic valve according to the invention ( 10 ) is preferably in a haemostatic cannula unit ( 70 ), as in the 1 and 2 For example, it is used for various cardiac catheter procedures in which a dilatation catheter or treatment catheter is advanced over a small guidewire into a blood vessel.
  • The haemostatic cannula unit ( 70 ) is essentially composed of five components, as in the 1 and 2 shown. The first of these ingredients is the cap ( 80 ) located at the proximal end of the second component, the longitudinally extending valve housing ( 90 ), is attached. The valve housing ( 90 ) has proximal and distal opposing openings through which elongated cylindrical medical devices into the interior of the valve housing (FIG. 90 ) can be introduced and led out of this. The cap ( 80 ) and the valve housing ( 90 ) of the cannula unit ( 70 ) are preferably made of a relatively rigid thermoplastic material, such as a high density polyethylene or an acrylonitrile butadiene styrene copolymer. The cap ( 80 ) can be attached to the body ( 96 ) of the valve housing ( 90 ), for example using threads, snaps, etc. or by gluing, but preferably it is attached by ultrasonic welding or heat sealing.
  • The third and fourth main constituents of the hemostatic cannula unit according to the invention ( 70 ) form the hä mostatischen valve ( 10 ) and consist of a proximal valve seal ( 20 ) and a distal valve seal ( 40 ), which in the 1 . 2 and 3 are shown. An entrance area ( 21 ) of the proximal valve seal ( 20 ) contacts the inner surface of the cap ( 80 ) of the haemostatic cannula unit ( 70 ), and an exit surface ( 23 ) of the proximal valve seal ( 20 ) contacts an entrance surface ( 41 ) of the distal valve seal ( 40 ), as in 1 shown. An exit surface ( 43 ) of the distal valve seal contacts a surface inside the valve housing ( 90 ), as in 1 shown to the valve seal ( 10 ) securely in the valve housing ( 90 ) to keep. The valve seals ( 20 . 40 ) are made of a soft, highly elastic polymeric material, such as of silicone rubber, or of a thermoplastic elastomer (olefin or styrene rubber or rubber based on polyamides, polyesters or hydrocarbons, such as polybutadiene, polyisoprene, or natural rubber), the easy and repeatable the passage of elongate cylindrical medical devices ( 120 ) of different diameter through the hemostatic valve ( 10 ) allowed.
  • The last main component of the haemostatic cannula unit according to the invention ( 70 ) is in the 1 and 2 illustrated tubular sheath, which is preferably made of a biocompatible thermoplastic material, such as a high density polyethylene (HDPE), a polypropylene, a fluoropolymer, a polyether block amide (PEBA), a polyamide (PA), a polyvinyl chloride (PVC), thermoplastic elastomers based on polyurethane or a mixture of the above-mentioned polymeric materials. It may be used for co-extrusion of the introducer sheath ( 100 Also, a multi-layered tubular structure can be used by using various combinations of the above-mentioned polymeric materials. The case ( 100 ) is inserted into the distal end ( 94 ) of the valve housing ( 90 ) and fixed there, preferably by heat sealing or ultrasonic welding, to an output from the interior of the valve housing ( 90 ).
  • like in the 1 and 2 is distal to the hemostasis valve (FIG. 10 ) on the valve housing ( 90 ) preferably a lateral inlet ( 110 ) or adapted to allow perfusion and aspiration of fluids through the sheath (FIG. 100 ).
  • Through the introductory cover ( 100 ), the percutaneous opening or access to the vasculature originally created with other devices, such as a syringe needle or scalpel, is kept open and provides access point for a dilator or obturator as well as for catheters and guidewires. The introductory cover ( 100 ) is introduced into the blood vessel by advancing a dilator over the guidewire, both advantageously through the introducer sheath (FIG. 100 ) and the valve ( 10 ) are pushed. Once the introducer sheath ( 100 ) has been advanced a sufficient distance into the selected blood vessel, the guidewire and dilator are removed and instead the therapeutic catheter system introduced, for example, in 10 is shown.
  • The proximal valve seal ( 20 ) and the distal valve seal ( 40 ) make that into the 1 . 2 and 3 illustrated haemostatic valve ( 10 ). The proximal valve seal ( 20 ) and the distal valve seal ( 40 ) are assembled by one or more, preferably two, Positioniervorsprünge ( 32 . 52 ) on each of the valve seals ( 20 . 40 ) are arranged, with one or more, preferably two, positioning grooves ( 34 . 54 ) on each of the valve seals ( 20 . 40 ), are brought into cover and introduced, as in 3 shown. The haemostatic valve ( 10 ) is at the perimal end ( 92 ) in the valve housing ( 90 ), as in 1 shown. Then the cap ( 80 ) on the proximal end ( 92 ) of the valve housing ( 90 ) attached. After assembly, there is a guide cone or conical receiving area ( 22 ) of the proximal valve seal ( 20 ) approximately in coincidence with an opening ( 84 ) in the cap ( 80 ). An inner circular section ( 82 ) of the cap ( 80 ), which extends outwardly from the inner surface of the cap, preferably exerts a slight axial pressure of the proximal valve seal (FIG. 20 ) against the distal valve seal ( 40 ) after the hemostatic cannula unit ( 70 ) was composed. As will be explained in detail below, the entrance area ( 21 ) of the proximal valve seal ( 20 ) and the output surface ( 43 ) of the distal valve seal each have raised concentric rings ( 30 . 50 ), for example, in the 1 . 3 . 4 and 6 are shown, and which are compressed when the hemostatic valve ( 10 ) in the valve housing ( 90 ) is inserted and fixed by the cap ( 80 ) at the proximal end of the valve housing ( 90 ) is attached. The pressure on the haemostatic valve ( 10 ) compresses it preferably by at least 2 percent, and preferably by about 2 to 5 percent within the valve housing ( 90 ).
  • The proximal valve seal ( 20 ) and the distal valve seal ( 40 ) are preferably formed with identical shape and structure. It is obvious that by the same structure the total manufacturing cost of the hemostatic valve ( 10 ) are reduced. Furthermore, the structure still has many advantages, which will be explained in more detail later. In the present context, however, the description of the structure and shape of the proximal valve seal ( 20 ) equally for the structure of the distal valve seal ( 40 ).
  • The proximal valve seal ( 20 ) contains a conical receiving area or a guide cone ( 22 ), which turns into a central or leadership hole ( 24 ), that in the 1 . 4 . 5A and 5B is shown, rejuvenated. The conical receiving area or guide cone ( 22 ) tapers at an angle of from about 20 to about 80 degrees, and preferably from about 20 to about 60 degrees, from the input surface (FIG. 21 ) of the valve seal ( 20 ). The central hole ( 24 ) serves as a sealing neck when a larger diameter catheter through the hemostatic valve ( 10 ) to be led. The central hole ( 24 ) can be formed with any cross-section that matches the outer geometry of the medical instruments to be inserted. For example, the cross section of this hole ( 24 ) rectangular, triangular, elliptical or round. If a circular cross section for the central hole ( 24 ), as in the 4 and 5A the diameter is preferably that of the smallest dilator connected to the haemostatic cannula unit ( 70 ) is used. A circular cross section, as in the 4 and 5A is preferred, for example, a cross section for receiving a dilator with 4 French (1.33 mm). The guide hole ends distally in a flat surface ( 25 ).
  • The guide or central hole ( 24 ) ( 4 and 5A ) and the conical receiving area ( 22 ) bring together medical devices to the center of the proximal valve seal ( 20 ) of the hemostasis valve ( 10 ) and allow easy introduction of a wide variety of different diameter catheters into, and through, the haemostatic valve (FIG. 10 ) and still provide an excellent "feeling" for the doctor.
  • Distal of the guide hole ( 24 ) of the valve seal ( 20 ) the slot extends ( 26 ) of the valve seal ( 20 completely through the remaining Proportion of valve seal ( 20 ) to the exit area ( 23 ), as in the 1 and 5A is shown. This slot ( 26 ) is preferably a single slot with its proximal end at or near the center of the pilot hole (FIG. 24 ) is located. The width of the slot ( 26 ) is about 0.070 inches (1.8 mm) to about 0.15 inches (3.8 mm), preferably about 0.09 inches (2.3 mm) to about 0.12 inches (3.0 mm).
  • As in 4 shown is the slot ( 26 preferably at an angle of from about 5 to about 70 degrees to the normal of the outer surface ( 23 ) of the proximal valve seal ( 20 ) cut. At best, the angle of this cut is about 44 to 46 degrees to the vertical. The slot ( 46 ) is preferably centered in the axial direction, so that its proximal end and its distal end from the central longitudinal axis of the hemostatic cannula unit ( 70 ) are equidistant. The slot ( 26 ) is also radially centered. These basic arrangements are also from the in 9 shown slots ( 26 . 46 ) can be seen. Because the width of the slot ( 26 ) (and the corresponding slot ( 46 )) is preferably greater than the inner diameter of the guide hole ( 24 ), the slot extends partly above and partly below the conical region ( 22 ), whereby two sections ( 31 ) of the slot ( 26 ) become visible (see 4 ). (See also the correspondingly cut sections ( 51 ) of the distal valve seal ( 40 ) in 6 .) By the angling of the slots ( 26 . 46 ) in the described manner thin portions of elastomeric material at the beginning and end portions of the slots ( 26 . 46 ) so that these areas conform to the surface geometry of a medical device ( 120 ) can adjust better. Since the thin regions of the elastomer adapt to this surface geometry, it is easier to prevent the entry of air and other substances into the vascular system. Similarly, leakage of blood between the medical device and the interior regions of the valve ( 10 ) prevented. Other advantages will be apparent from the following. Alternatively, as in 5B shown, the slot ( 26 ) at right angles to the surface of the starting surface ( 23 ) and to the surface ( 25 ) of the guide hole ( 24 ).
  • The starting area ( 23 ) of the proximal valve seal ( 20 ) includes a recessed bevelled edge ( 28 ), which in the 5 . 5A and 5B which is at an angle of from about 20 to about 90 degrees, and preferably from about 30 to about 60 degrees, from the starting surface (FIG. 23 ) of the proximal valve seal ( 20 ) is angled. By in the 5 . 5A and 5B represented angle of the bevelled edges ( 28 ) of the proximal valve seal ( 20 ) when advancing an elongate, cylindrical medical device through the hemostatic valve (FIG. 10 ) to the haemostatic valve ( 10 ) is converted substantially from an axial pressure to a radial pressure and thus a seamless valve seal ( 20 . 40 ), providing a better "feel" to the physician. In addition, the material of this bevelled edge ( 28 ) of the proximal valve seal ( 20 ) radially out when the medical device to be inserted through the hemostatic valve ( 10 ) is introduced. The space between the bevelled edge ( 28 ) of the proximal valve seal ( 20 ) and the inner surface of the valve housing ( 90 ) is gradually filled with the expanding material of the proximal valve seal ( 20 ), whereby the difficulty of inserting the medical device through the hemostatic valve ( 10 ) is reduced.
  • The second main component of the haemostatic valve ( 10 ) is the distal valve seal ( 40 ), which in the 6 . 6B and 7 is shown. It serves to supplement the proximal valve seal ( 20 ) and cooperates with it to provide an improved seal on small guidewires. It is formed with the same shape as the proximal valve seal ( 20 ), only in reverse, as in 3 represented, so that the input surface ( 41 ) of the distal valve seal ( 40 ) with the output surface ( 23 ) of the proximal valve seal ( 20 ), as in 1 shown. The advantages of a preferably identical shape of the seals ( 20 ) and ( 40 ) are obvious. For example, parts of each seal can be made with the same shape. Likewise, the same methods can be used to stock and handle the parts in the inventory.
  • The distal valve seal ( 40 ) also includes a bevelled edge ( 48 ). This bevelled edge ( 48 ) of the distal valve seal ( 40 ) acts with the bevelled edge ( 28 ) of the proximal valve seal ( 20 ) together. Their angle is complementary to the angle of the beveled edge ( 28 ) of the proximal valve seal ( 20 ).
  • Near the middle of the distal valve seal ( 40 ) is the slot ( 46 ), which in the 6 . 6B . 7 and 9 is shown, and preferably in a position perpendicular to the position of the slot ( 26 ) of the proximal valve seal ( 20 ) is arranged when the proximal valve seal ( 20 ) and the distal valve seal ( 40 ) are connected, as in the 1 and 3 shown. The width of the slot ( 46 ) of the distal valve seal ( 40 ) is preferably the same as the width of the slot ( 26 ) of the proximal valve seal ( 20 ). The slot ( 46 ) of the distal valve seal ( 40 ) extends through the distal valve seal ( 40 ) to a guide, central or guardian hole ( 44 ), as in the 6 and 6B shown. The leadership hole ( 44 ) of the distal valve seal ( 40 ) plays an important role in the introduction of medical devices through the hemostatic valve ( 10 ), especially in curved medical devices. When introducing curved medical devices through the central hole ( 24 ) and the slot ( 26 ) of the proximal valve seal ( 20 ), these tend to deviate from the middle of the hemostatic valve ( 10 ). Due to the presence of a second central or pilot hole ( 44 ) in the distal valve seal ( 40 ), the curved medical device pushed through the hemostasis valve is forced to pass straight through the hemostatic valve (FIG. 10 ) to happen. The leadership hole ( 44 ) goes proximally from the flat surface ( 45 ) out.
  • To increase the resistance of the hemostatic valve ( 10 ) in the implementation of medical devices, it is preferred to use the route which the medical device in the hemostatic valve ( 10 ) as small as possible. This can be achieved by the hemostatic valve ( 10 ) with a "back-to-back" arrangement of proximal valve seal ( 20 ) and distal valve seal ( 40 ) is used. This "back-to-back" arrangement will increase the thickness of the hemostatic valve ( 10 ) at the point where the medical device passes through the hemostatic valve ( 10 ), kept minimal. In a preferred embodiment, the thickness of this portion of the hemostatic valve ( 10 ) compared to the total thickness of the hemostatic valve ( 10 ) kept minimal. For example, the thickness of the slot area (between the starting area ( 23 ) and the flat surface ( 25 ) or the input surface ( 41 ) and the flat surface ( 45 )) both the proximal and the distal valve seal ( 20 . 40 ) in the 5B and 7B preferably about 0.10 inches (0.25 mm) to about 0.03 inches (0.8 mm). This is in 6B , Reference number 60 , clarifies. The thickness of the slot ( 46 ) is in 7 with the reference number 60 designated. The central hole ( 44 ) has approximately the same thickness in the longitudinal direction as the thickness of the slot ( 46 ). The total thickness of the slot area ( 60 ) and the central hole ( 44 ) together in the longitudinal direction, with the reference number ( 62 Therefore, it is preferably about 0.02 inches (0.5 mm) to 0.06 inches (1.6 mm).
  • In contrast, the thickness of the proximal valve seal ( 20 ) or the distal valve seal ( 40 ) from the respective entrance surfaces ( 21 . 41 ) to the respective starting surfaces ( 23 . 43 ) considerably thicker than the thickness of the respective slots ( 26 . 46 ), with the reference number 64 or the thickness of the respective slot area ( 60 ) and the central holes ( 24 . 44 ) together ( 62 ). In determining the thickness of, for example, the distal valve seal ( 40 ) (or the proximal valve seal ( 20 )), the thickness of the input surface ( 41 ) on the proximal side of the distal valve seal ( 40 ) to the exit area ( 43 ) on the distal side of the distal valve seal ( 40 ). This thickness of the distal valve seal ( 40 ), with the reference number ( 64 ) is preferably about 0.07 inches (1.8 mm) to about 0.15 inches (3.8 mm). The fat ( 60 ) of the slot ( 46 ) of the distal valve seal ( 40 ) is therefore preferably less than about 25 percent of the total thickness ( 64 ) of the distal valve seal, and more preferably about 10 to about 40 percent of that thickness ( 64 ).
  • The split slots ( 26 . 46 ) passing through the slot ( 26 ) of the proximal valve seal ( 20 ) and the slot ( 46 ) of the distal valve seal ( 40 ) act as a primary crossed seal barrier to prevent blood and air from passing through the hemostasis valve (FIG. 10 ) can pass through. To ensure correct alignment of the proximal valve seal ( 20 ) and her slot ( 26 ) with the slot ( 46 ) of the distal valve seal ( 40 ) are one or more, preferably two, Positioniervorsprünge ( 32 ) on the outer edge ( 29 ) of the proximal valve seal ( 20 ) provided in one or more, preferably two, positioning grooves ( 54 ) on the outer edge ( 49 ) of the distal valve seal ( 40 ) intervene, as in 3 shown. By aligning the respective positioning projections ( 32 ) of the proximal valve seal ( 20 ) with the positioning grooves ( 54 ) of the distal valve seal ( 40 ), the respective slots ( 26 . 46 ) radially perpendicular to each other and ensure a correct relative position of the distal valve seal ( 40 ) and the proximal valve seal ( 20 ) and there is a preferred crossed seal pattern within the hemostatic valve ( 10 ), as it is in the 1 and 3 is shown. In addition, in a preferred embodiment, the slot ( 46 ) of the distal valve seal ( 40 ) at a position between the respective positioning projections (FIG. 52 ), as in 7 shown, and perpendicular to one between the respective positioning grooves ( 54 ) formed line. The proximal valve seal ( 20 ) contains a similar structure for its slot ( 26 ), as in 5 is shown. Preferably, at the outer edge ( 49 ) of the distal valve seal ( 40 ) an additional pair of positioning projections ( 52 ) mounted in one or more, preferably two, positioning grooves ( 34 ) on the outer edge ( 29 ) of the valve seal ( 20 ) intervene, as in 3 is shown. (Although the seals ( 20 . 40 ) are preferably aligned so that the respective slots ( 26 . 46 ) are perpendicular to each other, the slots ( 26 . 46 ) so that the angle between the slots ( 26 . 46 ) up to 45 degrees or more from the Vertical deviates, if desired).
  • The structure of the complementary positioning projections ( 32 . 52 ) and positioning grooves ( 34 . 54 ) in both the proximal and distal valve seals ( 20 . 40 ) results in a correct alignment of the proximal valve seal ( 20 ) with respect to the distal valve seal ( 40 ), when the two seals are assembled. In addition, in a preferred embodiment, the distance between the inner surface of each pair of positioning protrusions (FIG. 52 ) slightly smaller than the inner diameter of the distal valve seal ( 40 ) provided grooves ( 54 ), as in 7 shown. Are the respective positioning projections ( 32 ) of the proximal valve seal ( 20 ) into the grooves ( 54 ) of the distal valve seal ( 40 ), this structure causes an outward pressure on the respective positioning projections ( 32 ) is exercised. By this outward pressure of the slot ( 26 ) of the valve seal ( 20 ) when snapping into the respective projections ( 32 ) slightly stretched. This causes a better seal to control blood flow through the valve ( 10 ) and causes a tight closure of the slot ( 26 ), even though there is no medical device to be inserted in the haemostatic valve ( 10 ) is located.
  • When using the angled slot, as in the 5A and 6 shown, the end or distal edge of the slot ( 26 ) from the valve seal ( 20 ) at the exit surface ( 23 ) out. Because the slot ( 46 ) perpendicular to the slot ( 26 ), they intersect at a single point. When operating the seal ( 20 ) and the seal ( 40 ), the distal edge of the slot ( 26 ) through the entrance area ( 41 ) is forced to a closed position. The thinner elastomeric region of the slot ( 26 ) retains its ability to conform to the outer diameter of an inserted medical device ( 120 ), but at the same time is advantageous because of the less elastic, thicker input surface ( 41 ) is forced to a closed position. Similarly, the guiding or proximal edge ( 46 ) in the valve seal ( 40 ) at the exit surface ( 23 ) one. The starting area ( 23 ) therefore supports the thinner proximal elastomeric region of the slot ( 46 which in turn retains the ability to conform to the outer diameter of an inserted medical device. The axial distal edge of the slot ( 46 ) also has a thin area. This area is thin and pliable to accommodate the outline of the medical device, but is forced to the closed position by the pressure exerted by a fluid column (blood) in communication with the circulatory system having a normal pressure.
  • The three thin elastomeric areas of the slots ( 26 and 46 Not only do they better address the outline of medical devices, they can also return to their original state more quickly if they were distracted, sometimes over a period of many hours, and so can completely separate the blood from the surrounding space. In other words, the thin areas allow the valve ( 10 ) closes completely and quickly, returning to their original state faster than thick areas deflected for extended periods of time.
  • The entrance area ( 21 ) of the proximal valve seal ( 20 ) preferably has the same structure and shape as the exit side (FIG. 43 ) of the distal valve seal ( 40 ). In a preferred embodiment, each of these surfaces ( 21 . 43 ) one or more concentric rings ( 30 . 50 ), which are raised above the top of the surfaces ( 21 . 43 ) lie. (See, for example, the two concentric rings ( 30 . 50 ) on the starting surfaces ( 23 . 43 ) of the valve seals ( 20 . 40 ) in the 3 . 4 and 6 .) These concentric rings ( 30 . 50 ) are slightly above the surface of the starting surface ( 43 ). Each of these concentric rings ( 30 . 50 ) is pressurized when the cap ( 80 ) on the valve housing ( 90 ) is attached (see 1 ). Because by increasing the concentric rings ( 30 . 50 ) a smaller proportion of the elastomeric material is pressurized, is within the valve housing ( 90 ) at the periphery a better seal through the hemostatic valve ( 10 ) against the blood flow around the outside of the hemostatic valve ( 10 ) is reached when there is no elongate medical device within the hemostatic valve ( 10 ) is located.
  • 8th shows the deformation of the respective slots ( 26 . 46 ) in the introduction of an elongate cylindrical device ( 120 ) through the hemostatic valve. To form this shape, there are two curved triangular spaces ( 27 . 47 ) at the ends of the respective slots ( 26 . 46 ) educated. The spaces ( 27 ) of the proximal valve seal and those ( 47 ) of the distal valve seal ( 40 ) intertwine when a cylindrical device ( 120 ) through the distal valve seal ( 40 ) and the proximal valve seal is guided (see 8th ). The interweaving of the gaps ( 27 . 47 ) each of the proximal valve seal and the distal valve seal ( 40 ) form a common barrier against leakage of blood from the hemostasis valve. Leakage of blood occurs only when the two adjacent interlaced spaces ( 27 . 47 ) get connected. Is the diameter of the inserted elongate cylindrical device ( 120 ) too small, two adjacent spaces ( 27 . 47 ) in dependent remain connected by the radial pressure through the hemostasis valve. In these cases, leakage of blood is prevented by the initial radial compression. Is the diameter of the elongated cylindrical device ( 120 ) are too large, can connect interlaced spaces of a conventional hemostatic valve and form a passage, so that blood can leak along the circumference of the catheter. This problem is exacerbated when the imported medical device ( 120 ) is turned during the introduction by the doctor. Due to the shape and structure of the proximal valve seal or the distal valve seal ( 40 ) leakage of blood may occur due to the complementary sealing capability of the pilot holes ( 24 . 44 ) whose diameter is smaller than the diameter of some large catheters used with the present hemostasis valve can be reduced or prevented.
  • 9 shows an enlarged view of the axial portion of the hemostasis valve ( 10 ) of distal. The axial distal edge of the slot ( 46 ) is in the plan view of the flat surface ( 45 ) visible, with the proximal and distal areas are shown in dashed lines. The proximal edge of the slot ( 46 ) is shown in dashed lines and with the reference number 46a Mistake. Similarly, the distal edge of the slot ( 26 ) (on the output surface ( 23 ), please refer 5B ) dashed lines and with the reference number 26a characterized. The proximal and distal portions of the slot ( 26 ) (on the flat surface 25 , please refer 4 and 5A ) are also shown in dashed lines and with the reference number 26b Mistake.
  • When an elongated medical device ( 120 ) as in 10 represented by the hemostatic valve according to the invention ( 10 ) is due to the axial stiffness of the proximal and distal valve seals ( 20 . 40 ) automatically the deformation of the valve ( 10 ) structurally deflected from the axial direction in a radial direction. In addition, due to the overall thin design of the slots ( 26 . 46 ) of the proximal valve seal ( 20 ) or the distal valve seal ( 40 ) reduces the resistance necessary to introduce a medical device ( 120 ) through the valve seal ( 10 ) necessary is. During the introduction, the beveled edges ( 28 . 38 ) of the proximal valve seal ( 20 ) and the distal valve seal ( 40 ) in the direction of the wall of the valve housing ( 90 ) deflected. However, since this radial expansion is perpendicular to the slot (FIG. 26 ) in the valve seal ( 20 ), the sealing ability of the hemostatic valve ( 10 ) is not affected.
  • The slots ( 26 . 46 ) are also due to the structure of the respective Positioniervorsprünge ( 32 . 52 ) with respect to the respective positioning grooves ( 34 . 54 ) stretched. This also means that the total resistance for insertion, previously due to friction in the implementation of the medical device ( 120 ) through the slots ( 26 . 46 ) of the hemostasis valve ( 10 ), is diminished.
  • The backward pressure of the blood acts against the starting surface ( 43 ) of the distal valve seal ( 40 ). Due to the structural properties of the present hemostatic valve ( 10 ), including in particular the relative thinness at the location where medical devices are being performed, holding the proximal valve seal ( 20 ) and the distal valve seal ( 40 ) contact each other substantially during the insertion of elongate medical devices and form a seamless seal pair having a reduced insertion resistance.
  • If a catheter is withdrawn during the procedure of catheterization, the deformation of the valve ( 10 ) Also deflected automatically in the radial direction. The backward pressure interacts with the resistance created by the compression of the proximal valve seal (FIG. 20 ) and the distal valve seal ( 40 ), also self-cleaning upon retraction of the elongated cylindrical medical device ( 120 ).
  • Because of these structural characteristics of the hemostatic valve ( 10 ) and the difference in the thickness of the proximal valve seal ( 20 ) and the distal valve seal ( 40 ) at the specific location where the medical device ( 120 ), the deformations of the proximal valve seal ( 20 ) and the distal valve seal ( 40 ) primarily in the radial direction and not in the axial direction during both insertion and withdrawal of an elongated cylindrical medical device. Because the haemostatic valve ( 10 ) in the valve housing ( 90 ) occupy approximately the same space before, during, and after the insertion and withdrawal of the elongate cylindrical medical device, the ingress of air into the bloodstream is prevented. Is the haemostatic cannula unit ( 70 ), medical devices having a wide range of diameters can be easily inserted.
  • For use, the elongated cylindrical medical device ( 120 ) through the circular opening ( 84 ) in the cap ( 80 ) into the haemostatic valve ( 10 ) introduced. Is the medical device ( 120 slightly eccentric introduced, it is through the conical receiving area or the guide cone ( 22 ) to the leadership hole ( 24 ) of the proximal valve seal ( 20 ) guided. The medical device ( 120 ) is then inserted into the slot ( 26 ) of the proximal valve seal ( 20 ) and further into the slot ( 46 ) and from the leadership hole ( 44 ) of the distal valve seal ( 40 ) advanced. After exiting the hemostatic valve ( 10 ) the medical device ( 120 ) through the introducer sheath ( 100 ) and advanced into the blood vessel. Any blood between the shell ( 100 ) and the medical device ( 120 ) in the interior of the valve housing ( 90 ) is due to the sealing effect of the pair of slots ( 26 . 46 ) and the proximal valve seal ( 20 ) and the distal valve seal ( 40 ) of the hemostasis valve ( 10 ) around the body of the medical device ( 120 ) prevented it from leaving. Due to the unique structural properties of the hemostasis valve according to the invention ( 10 ) and the structural relationships between the proximal valve seal ( 20 ) and the distal valve seal ( 40 ), the insertion resistance is reduced, and the medical device is cleaned of adhering blood, and even during retraction, no air can enter the bloodstream.

Claims (14)

  1. Hemostatic valve ( 10 ) comprising a proximal valve seal ( 20 ) containing a slot ( 26 ), and a distal valve seal ( 40 ) containing a slot ( 46 ), a positioning groove ( 34 ) in the proximal valve seal ( 20 ) and a positioning projection ( 52 ) in the distal valve seal ( 40 ), characterized in that the positioning projection ( 52 ) of the distal valve seal ( 40 ) in the positioning groove ( 34 ) of the proximal valve seal ( 20 ), and wherein when the positioning projection ( 52 ) in the positioning groove ( 34 ), the axial rotation of the proximal valve seal ( 20 ) in relation to the distal valve seal ( 40 ) is restricted.
  2. Hemostatic valve ( 10 ) according to claim 1, wherein the distal valve seal ( 40 ) further comprises a substantially flattened disc and a raised circular ring ( 50 ) on the distal side ( 43 ) of the substantially flattened disc.
  3. A hemostatic valve according to any one of claims 1 or 2, wherein the proximal valve seal ( 20 ) and the distal valve seal ( 40 ) are formed with the same shape.
  4. Hemostatic valve ( 10 ) according to one of claims 1 to 3, wherein the proximal valve seal ( 20 ) further comprises a second positioning groove ( 34 ), wherein the distal valve seal ( 40 ) further has a second positioning projection ( 52 ) and wherein the inner diameter of the positioning projections ( 52 ) is less than the diameter of the positioning grooves ( 34 ).
  5. Hemostatic valve ( 10 ) according to claim 4, wherein the pair of positioning projections ( 52 ) on an outer edge ( 49 ) of the distal valve seal ( 40 ) is about 180 degrees apart.
  6. Hemostatic valve ( 10 ) according to claim 5, wherein the slot ( 46 ) of the distal valve seal ( 40 ) between the two positioning projections ( 52 ) runs.
  7. A hemostatic valve according to any one of claims 1 to 6, wherein the proximal valve seal ( 20 ) further comprises a conical receiving area ( 22 ) and one with the slot ( 26 ) associated guide hole ( 24 ), and wherein the distal valve seal ( 40 ) further comprises a conical receiving area ( 42 ) and one with the slot ( 46 ) of the distal valve seal ( 40 ) associated guide hole ( 44 ).
  8. Hemostatic valve ( 10 ) according to one of claims 1 to 7, wherein the slot ( 26 ) of the proximal valve seal ( 20 ) is disposed at an angle of about 5 to about 70 degrees from a vertical line extending from a flattened surface of the valve seal (10). 20 ).
  9. A hemostatic valve according to any one of claims 1 to 8, wherein the thickness ( 60 ) of the slot ( 26 ) of the proximal valve seal ( 20 ) less than about 40 percent of the thickness ( 64 ) of the proximal valve seal ( 20 ) between their entry ( 21 ) and exit pages ( 23 ) is.
  10. Hemostatic cannula unit ( 70 ), comprising a longitudinally extending valve housing ( 90 ) having a first opening and a central, longitudinally extending chamber communicating with a second opening; a cap ( 80 ) attached to the valve housing ( 90 ) and the first opening in the valve housing ( 90 ) and provides an opening to allow insertion of a medical device into the first opening of the housing (FIG. 90 ) through the central chamber and out of the second opening; and a haemostatic valve ( 10 ) according to claim 1.
  11. Hemostatic cannula unit ( 70 ) according to claim 10, wherein the proximal valve seal ( 20 ) continue to produce a beveled portion ( 28 ), wherein the bevelled portion ( 28 ) a space between the hemostatic valve ( 10 ) and an inner surface of the valve housing ( 90 ) when the haemostatic valve ( 10 ) within the valve housing ( 90 ) is located.
  12. Hemostatic cannula unit ( 70 ) according to one of claims 10 or 11, wherein the cap ( 80 ) when attached to the valve body ( 90 ), the haemostatic valve ( 10 ) is pressurized so that the thickness of the hemostatic valve ( 10 ) is compressed by at least about 2 percent.
  13. Hemostatic cannula unit ( 70 ) according to any one of claims 10 to 12, wherein after insertion of a medical device through the hemostatic valve ( 10 ) a distal side ( 23 ) of the proximal valve seal ( 20 ) and a proximal side ( 41 ) of the distal valve seal ( 40 ) remain in contact when the medical device passes through the hemostatic valve ( 10 ) is introduced.
  14. Hemostatic cannula unit ( 70 ) according to any one of claims 10 to 13, wherein the thickness ( 60 ) of the slot ( 26 ) of the proximal valve seal ( 20 ) less than about 40 percent of the thickness ( 64 ) of the proximal valve seal ( 20 ) between their entry ( 21 ) and exit pages ( 23 ) is.
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US491221 2000-01-25
US09/491,221 US6551283B1 (en) 2000-01-25 2000-01-25 Hemostasis valve
US734391 2000-12-11
US09/734,391 US6632200B2 (en) 2000-01-25 2000-12-11 Hemostasis valve
PCT/US2001/001588 WO2001054763A2 (en) 2000-01-25 2001-01-18 Hemostasis valve

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JP (1) JP4940526B2 (en)
AT (1) AT277665T (en)
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011088337A1 (en) * 2011-12-13 2013-06-13 Karl Storz Gmbh & Co. Kg Sealing device for sealing a passage for a medical instrument

Families Citing this family (124)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6663599B2 (en) * 1992-05-06 2003-12-16 Cook Incorporated Hemostasis cannula
US8753317B2 (en) * 1992-05-06 2014-06-17 Cook Medical Technologies Llc Hemostasis cannula
US8992085B2 (en) * 1999-06-24 2015-03-31 Alan D. Olin Self-supporting storage bag with resealable pour spout
US6551283B1 (en) * 2000-01-25 2003-04-22 St. Jude Medical, Daig Division Hemostasis valve
US6506181B2 (en) * 2001-05-25 2003-01-14 Becton, Dickinson And Company Catheter having a low drag septum
US20070038244A1 (en) * 2001-06-08 2007-02-15 Morris Edward J Method and apparatus for sealing access
US7993365B2 (en) * 2001-06-08 2011-08-09 Morris Innovative, Inc. Method and apparatus for sealing access
US20060004408A1 (en) * 2001-06-08 2006-01-05 Morris Edward J Method and apparatus for sealing access
AU2002259265B2 (en) * 2001-07-27 2008-06-05 Becton, Dickinson And Company Luer connector assembly
US7347829B2 (en) * 2002-10-07 2008-03-25 Suros Surgical Systems, Inc. Introduction system for minimally invasive surgical instruments
US7988679B2 (en) 2003-03-18 2011-08-02 Navilyst Medical, Inc. Pressure responsive slit valve assembly for a plurality of fluids and uses thereof
US9486241B2 (en) 2003-03-21 2016-11-08 Ethicon Endo-Surgery, Llc Trocar seal assembly
US8147457B2 (en) * 2003-03-21 2012-04-03 Ethicon Endo-Surgery, Inc. Conical trocar seal
US7435236B2 (en) 2003-06-27 2008-10-14 Navilyst Medical, Inc. Pressure actuated valve with improved biasing member
US7985232B2 (en) * 2003-07-08 2011-07-26 St. Jude Medical, Atrial Fibrillation Division, Inc. Detachable hemostasis valve and splittable sheath assembly
US7241276B2 (en) 2003-08-06 2007-07-10 Trivascular, Inc. Passive hemostatic sheath valve
CA2536571A1 (en) * 2003-08-26 2005-03-03 Zerusa Limited A haemostasis device
US7252652B2 (en) * 2003-08-29 2007-08-07 Boston Scientific Scimed, Inc. Valved catheters including high flow rate catheters
US8206411B2 (en) * 2003-09-30 2012-06-26 Ethicon Endo-Surgery, Inc. Trocar housing/stop-cock assembly
US8012128B2 (en) * 2003-09-30 2011-09-06 Ethicon Endo-Surgery Inc. Button latching system for a trocar
US7785294B2 (en) * 2003-09-30 2010-08-31 Ethicon Endo-Surgery, Inc. Woven protector for trocar seal assembly
US8034032B2 (en) * 2003-09-30 2011-10-11 Ethicon Endo-Surgery, Inc. Multi-angled duckbill seal assembly
US7597701B2 (en) * 2003-09-30 2009-10-06 Ethican Endo-Surgery, Inc. Instrument lock assembly for trocar
US20050070850A1 (en) * 2003-09-30 2005-03-31 Albrecht Thomas E. Low-profile, recessed stop-cock valve for trocar assembly
US8029475B2 (en) * 2003-09-30 2011-10-04 Ethicon Endo-Surgery, Inc. Reinforced seal assembly
US20050070947A1 (en) * 2003-09-30 2005-03-31 Franer Paul T. Rotational latching system for a trocar
DE10346612A1 (en) * 2003-10-08 2005-05-19 Robert Bosch Gmbh Method for forecasting a temporal development of a system size
US20050240153A1 (en) * 2004-01-23 2005-10-27 Opie John C Vascular sheath
US20050171510A1 (en) * 2004-01-29 2005-08-04 Dicarlo Paul Pressure actuated safety valve with spiral flow membrane
US9314608B2 (en) 2004-01-29 2016-04-19 Angiodynamics, Inc Pressure activated safety valve with high flow slit
US9933079B2 (en) * 2004-01-29 2018-04-03 Angiodynamics, Inc. Stacked membrane for pressure actuated valve
US8187234B2 (en) * 2004-01-29 2012-05-29 Navilyst Medical, Inc. Pressure activated safety valve with anti-adherent coating
US8034035B2 (en) 2004-01-29 2011-10-11 Navilyst Medical, Inc. Pressure activated safety valve with high flow slit
US8083728B2 (en) 2004-03-18 2011-12-27 C. R. Bard, Inc. Multifunction adaptor for an open-ended catheter
US7594910B2 (en) 2004-03-18 2009-09-29 C. R. Bard, Inc. Catheter connector
US7854731B2 (en) 2004-03-18 2010-12-21 C. R. Bard, Inc. Valved catheter
US7594911B2 (en) 2004-03-18 2009-09-29 C. R. Bard, Inc. Connector system for a proximally trimmable catheter
US7377915B2 (en) 2004-04-01 2008-05-27 C. R. Bard, Inc. Catheter connector system
US7637893B2 (en) 2004-04-30 2009-12-29 C. R. Bard, Inc. Valved sheath introducer for venous cannulation
US9638770B2 (en) 2004-05-21 2017-05-02 Devicor Medical Products, Inc. MRI biopsy apparatus incorporating an imageable penetrating portion
US7708751B2 (en) 2004-05-21 2010-05-04 Ethicon Endo-Surgery, Inc. MRI biopsy device
US8932233B2 (en) 2004-05-21 2015-01-13 Devicor Medical Products, Inc. MRI biopsy device
WO2006028137A1 (en) * 2004-09-07 2006-03-16 Jms.Co., Ltd Valve and feeding catheter having the valve
US20060071432A1 (en) * 2004-09-29 2006-04-06 Staudner Rupert A Seal for trocar
US8926564B2 (en) 2004-11-29 2015-01-06 C. R. Bard, Inc. Catheter introducer including a valve and valve actuator
US8932260B2 (en) 2004-11-29 2015-01-13 C. R. Bard, Inc. Reduced-friction catheter introducer and method of manufacturing and using the same
US9597483B2 (en) 2004-11-29 2017-03-21 C. R. Bard, Inc. Reduced-friction catheter introducer and method of manufacturing and using the same
US8403890B2 (en) 2004-11-29 2013-03-26 C. R. Bard, Inc. Reduced friction catheter introducer and method of manufacturing and using the same
US7163525B2 (en) * 2004-12-17 2007-01-16 Ethicon Endo-Surgery, Inc. Duckbill seal protector
US7371227B2 (en) * 2004-12-17 2008-05-13 Ethicon Endo-Surgery, Inc. Trocar seal assembly
US7481795B2 (en) * 2004-12-17 2009-01-27 Ethicon Endo-Surgery, Inc. Circumferential trocar seal assembly
US8371555B2 (en) * 2005-01-04 2013-02-12 Pacesetter, Inc. Splittable hemostasis valve
US8328768B2 (en) * 2005-02-11 2012-12-11 Angiodynamics, Inc Pressure activated safety valve with improved flow characteristics and durability
US20060229655A1 (en) * 2005-03-30 2006-10-12 Ethicon Endo-Surgery, Inc. Two part bullet assembly
US7875019B2 (en) 2005-06-20 2011-01-25 C. R. Bard, Inc. Connection system for multi-lumen catheter
US7914519B2 (en) * 2005-06-23 2011-03-29 Elcam Medical Agricultural Cooperative Association, Ltd. Catheter device
US9168359B2 (en) 2005-06-30 2015-10-27 Abbott Laboratories Modular introducer and exchange sheath
US20100130937A1 (en) * 2005-06-30 2010-05-27 Abbott Vascular Inc. Introducer sheath and methods of making
US8440122B2 (en) * 2005-06-30 2013-05-14 Abbott Vascular Inc. Introducer sheath and methods of making
US9352118B2 (en) 2005-06-30 2016-05-31 Abbott Laboratories Modular introducer and exchange sheath
US20070066988A1 (en) * 2005-09-22 2007-03-22 Keshava Datta Trocar obturator with cutting edges
US7544293B2 (en) * 2005-09-26 2009-06-09 Semba Inc. Valve and process for interrupted continuous flow chromatography
US7731694B2 (en) * 2005-10-24 2010-06-08 Cardiac Pacemakers, Inc. Hemostasis seal
EP1954343B1 (en) 2005-12-02 2012-01-18 C.R.Bard, Inc. Pressure-activated proximal valves
US8585660B2 (en) * 2006-01-25 2013-11-19 Navilyst Medical, Inc. Valved catheter with power injection bypass
US20070254000A1 (en) * 2006-04-28 2007-11-01 Xiaoping Guo Biocompatible self-lubricating polymer compositions and their use in medical and surgical devices
US20100198160A1 (en) * 2006-06-28 2010-08-05 Abbott Vascular Inc. Expandable Introducer Sheaths and Methods for Manufacture and Use
US9889275B2 (en) 2006-06-28 2018-02-13 Abbott Laboratories Expandable introducer sheath to preserve guidewire access
US9597063B2 (en) 2006-06-28 2017-03-21 Abbott Laboratories Expandable introducer sheath to preserve guidewire access
EP2056899B1 (en) * 2006-08-30 2013-08-14 CircuLite, Inc. Systems for establishing supplemental blood flow in the circulatory system
US8807164B2 (en) * 2006-08-30 2014-08-19 Semba Biosciences, Inc. Valve module and methods for simulated moving bed chromatography
US7905823B2 (en) * 2006-08-30 2011-03-15 Circulite, Inc. Devices, methods and systems for establishing supplemental blood flow in the circulatory system
US7790040B2 (en) * 2006-08-30 2010-09-07 Semba Biosciences, Inc. Continuous isocratic affinity chromatography
US8333686B2 (en) * 2006-08-30 2012-12-18 Circulite, Inc. Cannula insertion devices, systems, and methods including a compressible member
JP4994775B2 (en) 2006-10-12 2012-08-08 日本コヴィディエン株式会社 Needle point protector
US7798991B2 (en) * 2006-11-14 2010-09-21 Genico, Inc. Trocar and cannula assembly having variable opening sealing gland and related methods
US20080172009A1 (en) * 2007-01-11 2008-07-17 Alcon, Inc. Self-Sealing Cannula
CA2631618A1 (en) * 2007-05-22 2008-11-22 Tyco Healthcare Group Lp Access assembly with ribbed seal
US8092431B2 (en) * 2007-05-24 2012-01-10 Smith & Nephew, Inc. Seal assembly for a cannula
US20080312662A1 (en) * 2007-06-13 2008-12-18 Hickingbotham Dyson W Self Sealing Cannula / Aperture Closure Cannula
US20090012476A1 (en) * 2007-07-05 2009-01-08 Galt Medical Corporation Hemostasis valve for a catheter introducer
US20090024106A1 (en) * 2007-07-17 2009-01-22 Morris Edward J Method and apparatus for maintaining access
JP5372762B2 (en) * 2007-09-27 2013-12-18 テルモ株式会社 Valve body and medical device
EP2213327B1 (en) * 2007-09-27 2013-10-30 Terumo Kabushiki Kaisha Valve element and medical instrument
US8608702B2 (en) 2007-10-19 2013-12-17 C. R. Bard, Inc. Introducer including shaped distal region
US8343029B2 (en) * 2007-10-24 2013-01-01 Circulite, Inc. Transseptal cannula, tip, delivery system, and method
US9474889B2 (en) * 2008-02-19 2016-10-25 Bipore Medical Devices, Inc. Sealing arrangement for medical introducer
US20110004062A1 (en) * 2008-03-24 2011-01-06 Hideaki Asai Anti-leak valve unit for overtube
US8043316B2 (en) 2008-05-02 2011-10-25 Suros Surgical Systems, Inc. Adjustable spacer
US8257321B2 (en) * 2008-05-21 2012-09-04 Navilyst Medical, Inc. Pressure activated valve for high flow rate and pressure venous access applications
US8118832B1 (en) 2008-06-16 2012-02-21 Morris Innovative, Inc. Method and apparatus for sealing access
US8196603B2 (en) 2008-08-20 2012-06-12 Semba Biosciences, Inc. Valve block assembly
EP2165731A1 (en) * 2008-09-19 2010-03-24 Terumo Medical Corporation Detachable and freely rotating hemostasis valve
US8337470B2 (en) * 2009-01-28 2012-12-25 Angiodynamics, Inc. Three-way valve for power injection in vascular access devices
US8083721B2 (en) 2009-01-29 2011-12-27 Navilyst Medical, Inc. Power injection valve
US7850653B2 (en) * 2009-03-23 2010-12-14 Tyco Healthcare Group Lp Access port including rotatable seals
US8460168B2 (en) * 2009-03-27 2013-06-11 Circulite, Inc. Transseptal cannula device, coaxial balloon delivery device, and methods of using the same
US20100249491A1 (en) * 2009-03-27 2010-09-30 Circulite, Inc. Two-piece transseptal cannula, delivery system, and method of delivery
US8337484B2 (en) 2009-06-26 2012-12-25 C. R. Band, Inc. Proximally trimmable catheter including pre-attached bifurcation and related methods
US8007468B2 (en) 2009-07-13 2011-08-30 Navilyst Medical, Inc. Method to secure an elastic component in a valve
US20110054487A1 (en) * 2009-09-02 2011-03-03 Circulite, Inc. Coaxial transseptal guide-wire and needle assembly
US8430812B2 (en) * 2009-10-05 2013-04-30 Covidien Lp Surgical access assembly
US20110087159A1 (en) * 2009-10-08 2011-04-14 Parihar Shailendra K Trocar Assembly
US8491533B2 (en) * 2009-10-08 2013-07-23 Ethicon Endo-Surgery, Inc. Trocar assembly
US8932249B2 (en) 2009-10-08 2015-01-13 Ethicon Endo-Surgery, Inc. Trocar assembly
US20110087093A1 (en) * 2009-10-09 2011-04-14 Navilyst Medical, Inc. Valve configurations for implantable medical devices
US20110118612A1 (en) * 2009-11-18 2011-05-19 Navilyst Medical, Inc. Valved Catheter with Integrated Pressure Measurement Capabilities
US8343106B2 (en) 2009-12-23 2013-01-01 Alcon Research, Ltd. Ophthalmic valved trocar vent
DK2515774T3 (en) 2009-12-23 2014-05-12 Alcon Res Ltd Ophthalmic trokar canon with valve
US20110190697A1 (en) * 2010-02-03 2011-08-04 Circulite, Inc. Vascular introducers having an expandable section
US8783654B2 (en) * 2010-03-26 2014-07-22 Hewlett-Packard Development Company, L. P. Fluid interconnect member, fluid interconnect system, and methods thereof
US8137321B2 (en) * 2010-05-12 2012-03-20 Medtronic Vascular, Inc. Introducer sheath
US9474544B2 (en) * 2010-07-06 2016-10-25 Pivot Medical, Inc. Method and apparatus for accessing the interior of a hip joint, including the provision and use of a novel inflow access cannula
US9522266B2 (en) 2011-02-28 2016-12-20 Gmedix, Inc. Hemostasis sealing device
ES2662356T3 (en) 2011-04-27 2018-04-06 Kpr U.S., Llc Safety IV catheter assemblies
JP6050750B2 (en) * 2011-07-04 2016-12-21 テルモ株式会社 Introducer sheath
DE102011108177B4 (en) * 2011-07-22 2013-03-21 Festo Ag & Co. Kg Valve module
US8628497B2 (en) 2011-09-26 2014-01-14 Covidien Lp Safety catheter
US8715250B2 (en) 2011-09-26 2014-05-06 Covidien Lp Safety catheter and needle assembly
WO2013056223A1 (en) 2011-10-14 2013-04-18 Covidien Lp Safety iv catheter assembly
US9895524B2 (en) 2012-07-13 2018-02-20 Angiodynamics, Inc. Fluid bypass device for valved catheters
US20140196792A1 (en) * 2013-01-17 2014-07-17 Global Medical Innovations, Llc Three-Way Valve Case Apparatus
US20180304041A1 (en) * 2014-09-01 2018-10-25 AUST Development, LLC Catheter hubs and valves for minimizing embolic potential
US10391292B2 (en) 2016-06-15 2019-08-27 Surmodics, Inc. Hemostasis sealing device with constriction ring

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR747066A (en) 1932-02-25 1933-06-10 Device, in gassed medium, supplying liquid or semi-liquid carriers respirators
US4000739A (en) 1975-07-09 1977-01-04 Cordis Corporation Hemostasis cannula
US4430081A (en) 1981-01-06 1984-02-07 Cook, Inc. Hemostasis sheath
US4436519B1 (en) 1981-05-28 1989-04-04
DE3323190C2 (en) 1983-06-28 1990-10-11 Michael Hoerauf Maschinenfabrik Gmbh & Co Kg, 7334 Suessen, De
US4655752A (en) 1983-10-24 1987-04-07 Acufex Microsurgical, Inc. Surgical cannula
JPH031026B2 (en) 1984-05-09 1991-01-09 Terumo Corp
JPS61154679A (en) 1984-12-28 1986-07-14 Terumo Corp Medical instrument
US4615531A (en) 1985-02-19 1986-10-07 Green George D Double ring piston sealing arrangement
US4705511A (en) 1985-05-13 1987-11-10 Bipore, Inc. Introducer sheath assembly
US4626245A (en) 1985-08-30 1986-12-02 Cordis Corporation Hemostatis valve comprising an elastomeric partition having opposed intersecting slits
US4723550A (en) 1986-11-10 1988-02-09 Cordis Corporation Leakproof hemostasis valve with single valve member
US4798594A (en) 1987-09-21 1989-01-17 Cordis Corporation Medical instrument valve
US4895565A (en) 1987-09-21 1990-01-23 Cordis Corporation Medical instrument valve
US4909798A (en) 1987-11-12 1990-03-20 Daig Corporation Universal hemostasis cannula
DE3809127C1 (en) 1988-03-18 1989-04-13 B. Braun Melsungen Ag, 3508 Melsungen, De
US4960412A (en) 1988-04-15 1990-10-02 Universal Medical Instrument Corp. Catheter introducing system
US4895346A (en) 1988-05-02 1990-01-23 The Kendall Company Valve assembly
US5000745A (en) * 1988-11-18 1991-03-19 Edward Weck Incorporated Hemostatis valve
US5149327A (en) 1989-09-05 1992-09-22 Terumo Kabushiki Kaisha Medical valve, catheter with valve, and catheter assembly
US5176652A (en) 1989-12-22 1993-01-05 Cordis Corporation Hemostasis valve
US5041095A (en) 1989-12-22 1991-08-20 Cordis Corporation Hemostasis valve
US5207656A (en) 1990-04-19 1993-05-04 Cordis Corporation Medical instrument valve having foam partition member
US5114408A (en) 1990-10-18 1992-05-19 Daig Corporation Universal hemostasis valve having improved sealing characteristics
JPH04170966A (en) 1990-11-01 1992-06-18 Nippon Sherwood Kk Valvular body for catheter introducer blood stop valve
JP2564222Y2 (en) * 1991-06-04 1998-03-04 株式会社トップ The valve body
US5154701A (en) * 1991-06-26 1992-10-13 Adam Spence Corporation Hemostasis valve
US5125903A (en) 1991-08-01 1992-06-30 Medtronic, Inc. Hemostasis valve
US5197955A (en) * 1991-10-18 1993-03-30 Ethicon, Inc. Universal seal for trocar assembly
US5395349A (en) 1991-12-13 1995-03-07 Endovascular Technologies, Inc. Dual valve reinforced sheath and method
CA2093754C (en) 1992-04-24 1996-08-13 David T. Green Valve assembly for introducing instruments into body cavities
US5269764A (en) 1992-08-21 1993-12-14 Devices For Vascular Intervention, Inc. Hemostatic gasket and valve assembly
US5342315A (en) * 1993-04-12 1994-08-30 Ethicon, Inc. Trocar seal/protector assemblies
US5520655A (en) 1994-07-15 1996-05-28 Cordis Corporation Catheter hemostasis valve
JP2699155B2 (en) * 1994-12-22 1998-01-19 株式会社グッドマン Catheter introducer of the hemostasis valve
US5643227A (en) 1995-01-19 1997-07-01 Stevens; Robert C. Hemostasis cannula valve apparatus and method of using same
US5858007A (en) 1996-07-03 1999-01-12 C. R. Bard, Inc. Hemostatic catheter introducer
WO1998013083A1 (en) 1996-09-26 1998-04-02 Symbiosis Corporation Catheter sheath introducer with improved hemostasis valve
DE29701600U1 (en) 1997-01-31 1997-07-10 Rycyk Manfred Valve mechanism for medical applications
US5779697A (en) * 1997-05-28 1998-07-14 Linvatec Corporation Arthroscopic cannula with fluid seals
US6277100B1 (en) * 1997-07-17 2001-08-21 Medical Components, Inc. Catheter guide wire introducing device and method
US6024729A (en) * 1998-03-10 2000-02-15 Vernay Laboratories, Inc. Hemostasis valve assembly including guide wire seal

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011088337A1 (en) * 2011-12-13 2013-06-13 Karl Storz Gmbh & Co. Kg Sealing device for sealing a passage for a medical instrument
EP2604203A1 (en) 2011-12-13 2013-06-19 Karl Storz GmbH & Co. KG Sealing device for sealing a feedthrough for a medical instrument
US9398923B2 (en) 2011-12-13 2016-07-26 Karl Storz Gmbh & Co. Kg Sealing means for the sealing of an introduction facility for a medical instrument

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US20020010425A1 (en) 2002-01-24
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WO2001054763A2 (en) 2001-08-02
JP4940526B2 (en) 2012-05-30

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