DE60105250D1 - Herstellungsverfahren zur 2-Cyclohexyl-2-hydroxy-Phenylessigsäure, Zwischenprodukt dafür und Herstellungsverfahren davon - Google Patents

Herstellungsverfahren zur 2-Cyclohexyl-2-hydroxy-Phenylessigsäure, Zwischenprodukt dafür und Herstellungsverfahren davon

Info

Publication number
DE60105250D1
DE60105250D1 DE60105250T DE60105250T DE60105250D1 DE 60105250 D1 DE60105250 D1 DE 60105250D1 DE 60105250 T DE60105250 T DE 60105250T DE 60105250 T DE60105250 T DE 60105250T DE 60105250 D1 DE60105250 D1 DE 60105250D1
Authority
DE
Germany
Prior art keywords
manufacturing process
hydroxy
cyclohexyl
phenylacetic acid
intermediate therefor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60105250T
Other languages
English (en)
Other versions
DE60105250T2 (de
Inventor
Tetsuya Ikemoto
Wei-Guo Gao
Mitsuhiro Takeda
Masami Igi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumika Fine Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumika Fine Chemicals Co Ltd filed Critical Sumika Fine Chemicals Co Ltd
Publication of DE60105250D1 publication Critical patent/DE60105250D1/de
Application granted granted Critical
Publication of DE60105250T2 publication Critical patent/DE60105250T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/36—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by hydrogenation of carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/303—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by hydrogenation of unsaturated carbon-to-carbon bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60105250T 2000-11-07 2001-11-07 Herstellungsverfahren zur 2-Cyclohexyl-2-hydroxy-Phenylessigsäure, Zwischenprodukt dafür und Herstellungsverfahren davon Expired - Lifetime DE60105250T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000339437 2000-11-07
JP2000339437 2000-11-07

Publications (2)

Publication Number Publication Date
DE60105250D1 true DE60105250D1 (de) 2004-10-07
DE60105250T2 DE60105250T2 (de) 2005-09-01

Family

ID=18814511

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60105250T Expired - Lifetime DE60105250T2 (de) 2000-11-07 2001-11-07 Herstellungsverfahren zur 2-Cyclohexyl-2-hydroxy-Phenylessigsäure, Zwischenprodukt dafür und Herstellungsverfahren davon

Country Status (6)

Country Link
US (1) US6777576B2 (de)
EP (1) EP1205464B1 (de)
AT (1) ATE275122T1 (de)
AU (1) AU776101B2 (de)
CA (1) CA2361156A1 (de)
DE (1) DE60105250T2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6777576B2 (en) * 2000-11-07 2004-08-17 Sumika Fine Chemicals Co., Ltd. Production method of 2-cyclohexyl-2-hydroxy-2-phenylacetic acid intermediate therefor and production method thereof
CN110483274A (zh) * 2019-08-26 2019-11-22 山东绅联生物科技有限公司 一种盐酸环喷托酯中间体的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1001261C2 (de) 1954-08-05 1957-07-04 Thomae Gmbh Dr K Verfahren zur Herstellung von basischen Estern endocyclisch substituierter Mandelsaeuren und ihren Salzen
JPH11193271A (ja) 1997-10-31 1999-07-21 Ss Pharmaceut Co Ltd アリール酢酸アミド誘導体又はその塩及びこれを含有する医薬
KR19990037220A (ko) 1997-10-31 1999-05-25 타이도 나오카타 아릴아세트산 아미드 유도체 또는 그 염 및 이를 함유하는 의약
US6013830A (en) 1998-03-30 2000-01-11 Sepracor Inc. Asymmetric grignard synthesis with cyclic 1,2 aminoalcohols
US5973182A (en) 1998-10-22 1999-10-26 Sepracor Inc. Carbonate Intermediates useful in the preparation of optically active cyclohexylphenylglycolate esters
US6140529A (en) 1998-10-22 2000-10-31 Sepracor Inc. Synthesis of optically active cyclohexylphenylglycolate esters
US6180823B1 (en) 1998-11-06 2001-01-30 Sepracor Inc. Stereoselective process for alkyl phenylglycolic acids
US6777576B2 (en) * 2000-11-07 2004-08-17 Sumika Fine Chemicals Co., Ltd. Production method of 2-cyclohexyl-2-hydroxy-2-phenylacetic acid intermediate therefor and production method thereof

Also Published As

Publication number Publication date
ATE275122T1 (de) 2004-09-15
EP1205464A3 (de) 2003-03-26
EP1205464A2 (de) 2002-05-15
AU8925701A (en) 2002-05-09
US6777576B2 (en) 2004-08-17
CA2361156A1 (en) 2002-05-07
US20030013911A1 (en) 2003-01-16
DE60105250T2 (de) 2005-09-01
EP1205464B1 (de) 2004-09-01
AU776101B2 (en) 2004-08-26

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SUMITOMO CHEMICAL COMPANY, LTD., OSAKA, JP

8327 Change in the person/name/address of the patent owner

Owner name: SUMITOMO CHEMICAL CO. LTD., TOKIO/TOKYO, JP

8364 No opposition during term of opposition