DE3933315A1 - Zellverarbeitungseinrichtung - Google Patents

Zellverarbeitungseinrichtung

Info

Publication number
DE3933315A1
DE3933315A1 DE3933315A DE3933315A DE3933315A1 DE 3933315 A1 DE3933315 A1 DE 3933315A1 DE 3933315 A DE3933315 A DE 3933315A DE 3933315 A DE3933315 A DE 3933315A DE 3933315 A1 DE3933315 A1 DE 3933315A1
Authority
DE
Germany
Prior art keywords
cell suspension
membrane separation
membrane
cells
separation device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE3933315A
Other languages
German (de)
English (en)
Other versions
DE3933315C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
Robert John Schuyler
Robert Lee White
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo BCT Inc
Original Assignee
Cobe Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cobe Laboratories Inc filed Critical Cobe Laboratories Inc
Publication of DE3933315A1 publication Critical patent/DE3933315A1/de
Application granted granted Critical
Publication of DE3933315C2 publication Critical patent/DE3933315C2/de
Granted legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/147—Microfiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0218—Multiple bag systems for separating or storing blood components with filters
    • A61M1/0222—Multiple bag systems for separating or storing blood components with filters and filter bypass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/22—Controlling or regulating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0405—Lymph
    • A61M2202/0407—Lymphocytes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Water Supply & Treatment (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • External Artificial Organs (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Centrifugal Separators (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines Containing Plant Substances (AREA)
DE3933315A 1988-10-06 1989-10-05 Zellverarbeitungseinrichtung Granted DE3933315A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/254,392 US4897185A (en) 1988-10-06 1988-10-06 Cell processing apparatus and method

Publications (2)

Publication Number Publication Date
DE3933315A1 true DE3933315A1 (de) 1990-04-12
DE3933315C2 DE3933315C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-06-09

Family

ID=22964128

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3933315A Granted DE3933315A1 (de) 1988-10-06 1989-10-05 Zellverarbeitungseinrichtung

Country Status (8)

Country Link
US (1) US4897185A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH0720490B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU605697B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1304309C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3933315A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2637610B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2224954B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1238403B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792372A (en) 1987-01-30 1998-08-11 Baxter International, Inc. Enhanced yield collection systems and methods for obtaining concentrated platelets from platelet-rich plasma
US5656163A (en) * 1987-01-30 1997-08-12 Baxter International Inc. Chamber for use in a rotating field to separate blood components
US5370802A (en) 1987-01-30 1994-12-06 Baxter International Inc. Enhanced yield platelet collection systems and methods
US5242384A (en) * 1989-11-13 1993-09-07 Davol, Inc. Blood pumping and processing system
US5171456A (en) * 1990-06-14 1992-12-15 Baxter International Inc. Automated blood component separation procedure and apparatus promoting different functional characteristics in multiple blood components
US5135667A (en) * 1990-06-14 1992-08-04 Baxter International Inc. Method and apparatus for administration of anticoagulant to red cell suspension output of a blood separator
US5549834A (en) 1991-12-23 1996-08-27 Baxter International Inc. Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
US5804079A (en) 1991-12-23 1998-09-08 Baxter International Inc. Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
US6007725A (en) 1991-12-23 1999-12-28 Baxter International Inc. Systems and methods for on line collection of cellular blood components that assure donor comfort
AU652888B2 (en) * 1991-12-23 1994-09-08 Baxter International Inc. Centrifugal processing system with direct access drawer
EP0572656B1 (en) * 1991-12-23 1997-11-05 Baxter International Inc. Centrifuge with separable bowl and spool elements providing access to the separation chamber
US5423738A (en) * 1992-03-13 1995-06-13 Robinson; Thomas C. Blood pumping and processing system
US5368555A (en) * 1992-12-29 1994-11-29 Hepatix, Inc. Organ support system
US5427695A (en) 1993-07-26 1995-06-27 Baxter International Inc. Systems and methods for on line collecting and resuspending cellular-rich blood products like platelet concentrate
US5906589A (en) * 1996-11-13 1999-05-25 Cobe Laboratories, Inc. Method and apparatus for occlusion monitoring using pressure waveform analysis
CA2346814A1 (en) 1998-10-16 2000-04-27 Mission Medical, Inc. Blood processing system
US6890291B2 (en) * 2001-06-25 2005-05-10 Mission Medical, Inc. Integrated automatic blood collection and processing unit
US7514075B2 (en) 2001-12-07 2009-04-07 Cytori Therapeutics, Inc. Systems and methods for separating and concentrating adipose derived stem cells from tissue
US20050095228A1 (en) 2001-12-07 2005-05-05 Fraser John K. Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
US7585670B2 (en) 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
CA2469370C (en) * 2001-12-07 2014-07-08 Macropore Biosurgery, Inc. Adipose-derived cell processing unit
US8105580B2 (en) 2001-12-07 2012-01-31 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to promote wound healing
US7771716B2 (en) * 2001-12-07 2010-08-10 Cytori Therapeutics, Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
US9597395B2 (en) * 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US7651684B2 (en) 2001-12-07 2010-01-26 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in augmenting autologous fat transfer
US8404229B2 (en) 2001-12-07 2013-03-26 Cytori Therapeutics, Inc. Methods of using adipose derived stem cells to treat acute tubular necrosis
US7595043B2 (en) 2001-12-07 2009-09-29 Cytori Therapeutics, Inc. Method for processing and using adipose-derived stem cells
WO2003089926A2 (en) * 2002-04-19 2003-10-30 Mission Medical, Inc. Integrated automatic blood processing unit
WO2006022194A1 (en) * 2004-08-23 2006-03-02 Semiconductor Energy Laboratory Co., Ltd. Electron injecting composition, and light emitting element and light emitting device using the electron injecting composition
US20090304644A1 (en) * 2006-05-30 2009-12-10 Cytori Therapeutics, Inc. Systems and methods for manipulation of regenerative cells separated and concentrated from adipose tissue
WO2008013863A2 (en) * 2006-07-26 2008-01-31 Cytori Therapeutics, Inc. Generation of adipose tissue and adipocytes
WO2010021993A1 (en) * 2008-08-19 2010-02-25 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of the lymphatic system and malignant disease
EP2424463B1 (en) * 2009-05-01 2016-12-28 Bimini Technologies LLC Systems, methods and compositions for optimizing tissue and cell enriched grafts
DE102009039554A1 (de) * 2009-09-07 2011-03-10 Phytolutions Gmbh Verfahren zum Ernten von Algen aus einer Algensuspension, erstes, zweites und drittes Algensuspensionskonzentrat sowie erstes, zweites und drittes Nährflüssigkeitsfiltrat
CN105641988B (zh) * 2015-12-02 2018-01-30 重庆浪尖渝力科技有限公司 生物样品混悬液自动分离设备的挂板组件
JP6989907B2 (ja) * 2016-09-27 2022-02-15 吉和 米満 懸濁液を無菌的に処理するための器具
US10596532B2 (en) * 2016-11-16 2020-03-24 Zyno Medical, Llc Isolatable automatic drug compounding system
EP3329948B1 (en) * 2016-12-01 2023-09-06 Fenwal, Inc. Blood component pooling device, system and method
US20200085340A1 (en) * 2018-09-18 2020-03-19 Case Western Reserve University Magneto-optical detection of a disease component using magnetic nanoparticles
EP4574184A1 (en) * 2023-12-18 2025-06-25 Fenwal, Inc. Leukoreduction and continuous-flow centrifugation of whole blood

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0156496A1 (en) * 1984-02-24 1985-10-02 Kuraray Co., Ltd. Apparatus for the treatment of plasma
US4680025A (en) * 1982-08-24 1987-07-14 Baxter Travenol Laboratories, Inc. Blood component collection systems and methods

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US4681677A (en) * 1978-02-17 1987-07-21 Olin Corporation Water processor having automatic shutoff and bypass means
US4322275A (en) * 1980-01-10 1982-03-30 Ionics Incorporated Fractionation of protein mixtures
US4416654A (en) * 1981-09-03 1983-11-22 Haemonetics Corporation Pheresis apparatus
DE3533306A1 (de) * 1985-09-18 1987-03-26 Adolf Reiter Verfahren zur auftrennung und klarfiltration von suspensionen und vorrichtung zu seiner durchfuehrung
US4728430A (en) * 1986-02-10 1988-03-01 Millipore Corporation Diafiltration method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4680025A (en) * 1982-08-24 1987-07-14 Baxter Travenol Laboratories, Inc. Blood component collection systems and methods
EP0156496A1 (en) * 1984-02-24 1985-10-02 Kuraray Co., Ltd. Apparatus for the treatment of plasma

Also Published As

Publication number Publication date
DE3933315C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-06-09
JPH02168960A (ja) 1990-06-29
AU605697B2 (en) 1991-01-17
IT8967853A1 (it) 1991-04-05
IT1238403B (it) 1993-07-26
JPH0720490B2 (ja) 1995-03-08
US4897185A (en) 1990-01-30
FR2637610A1 (fr) 1990-04-13
IT8967853A0 (it) 1989-10-05
GB2224954A (en) 1990-05-23
AU4248789A (en) 1990-04-12
FR2637610B1 (fr) 1994-07-22
CA1304309C (en) 1992-06-30
GB2224954B (en) 1992-04-08
GB8922449D0 (en) 1989-11-22

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Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
D2 Grant after examination
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: GAMBRO INC., LAKEWOOD, COL., US

8339 Ceased/non-payment of the annual fee