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DE3789679D1 - Genetische Sonden. - Google Patents

Genetische Sonden.

Info

Publication number
DE3789679D1
DE3789679D1 DE19873789679 DE3789679A DE3789679D1 DE 3789679 D1 DE3789679 D1 DE 3789679D1 DE 19873789679 DE19873789679 DE 19873789679 DE 3789679 A DE3789679 A DE 3789679A DE 3789679 D1 DE3789679 D1 DE 3789679D1
Authority
DE
Grant status
Grant
Patent type
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE19873789679
Other languages
English (en)
Other versions
DE3789679T2 (de )
Inventor
Alec John Jeffreys
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zeneca Ltd
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for mutation or polymorphism detection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Hybridisation probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes
DE19873789679 1986-03-19 1987-03-18 Genetische Sonden. Expired - Fee Related DE3789679D1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB8606719A GB8606719D0 (en) 1986-03-19 1986-03-19 Genetic probes

Publications (1)

Publication Number Publication Date
DE3789679D1 true DE3789679D1 (de) 1994-06-01

Family

ID=10594846

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19873789679 Expired - Fee Related DE3789679D1 (de) 1986-03-19 1987-03-18 Genetische Sonden.
DE19873789679 Expired - Lifetime DE3789679T2 (de) 1986-03-19 1987-03-18 Genetische Sonden.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19873789679 Expired - Lifetime DE3789679T2 (de) 1986-03-19 1987-03-18 Genetische Sonden.

Country Status (9)

Country Link
US (1) US5175082A (de)
EP (1) EP0238329B1 (de)
JP (2) JPH0630636B2 (de)
CN (1) CN87102927A (de)
DE (2) DE3789679D1 (de)
DK (1) DK140287D0 (de)
FI (1) FI871189A (de)
GB (2) GB8606719D0 (de)
RU (1) RU1788970C (de)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0186271B1 (de) * 1984-11-12 1991-12-18 THE LISTER INSTITUTE OF PREVENTIVE MEDICINE Royal National Orthopaedic Hospital Methode zur Charakterisierung einer genomischen DNA-Probe
FR2603047B1 (fr) * 1986-08-19 1990-03-02 Vassart Gilbert Sonde d'hybridation pour la detection de sequences nucleotidiques polymorphes contenues dans un echantillon d'adn humain ou animal, procede de detection de sequences d'adn polymorphes utilisant une telle sonde, ses applications biologiques
US4987066A (en) * 1986-11-07 1991-01-22 Max Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Process for the detection of restriction fragment length polymorphisms in eukaryotic genomes
EP0294098A1 (de) * 1987-05-29 1988-12-07 City Of Hope Synthetische DNS-Proben
GB8716367D0 (en) * 1987-07-10 1987-08-19 Reeders S T Genetic identification
GB8720855D0 (en) * 1987-09-04 1987-10-14 Oxford University Of Chancello Probe
JPH05501946A (de) * 1988-02-18 1993-04-15
EP0337625A3 (de) * 1988-04-13 1991-07-24 Imperial Chemical Industries Plc Proben
GB8913350D0 (en) * 1988-06-10 1989-07-26 Ici Plc Nucleotide sequences
EP0433367A1 (de) * 1988-09-08 1991-06-26 Lifecodes Corporation Sonden zum nachweis von restriktionsfragmentlängen-polymorphismus im humanen genom
GB8824531D0 (en) * 1988-10-20 1988-11-23 Ici Plc Polynucleotide probes
GB8926026D0 (en) * 1988-11-25 1990-01-10 Ici Plc Extended nucleotide sequences
US5192658A (en) * 1989-03-30 1993-03-09 Lifecodes Corporation Compositions and protocols applicable to genetic analysis
US5582979A (en) * 1989-04-21 1996-12-10 Marshfield Clinic Length polymorphisms in (dC-dA)n.(dG-dT)n sequences and method of using the same
WO1992013968A1 (en) * 1991-02-07 1992-08-20 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Monolocus-specific hypervariable probes
FR2680520B1 (fr) * 1991-08-22 1995-09-22 France Etat Armement Procede de detection de nouvelles regions hypervariables dans une sequence d'adn, sequences de nucleotides constituant des sondes d'hybridation et leur application biologique.
US5853989A (en) * 1991-08-27 1998-12-29 Zeneca Limited Method of characterisation of genomic DNA
DE69230736T2 (de) * 1991-08-27 2000-06-21 Zeneca Ltd Verfahren zur Charakterisierung genomischer DNA
US5629147A (en) * 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
ES2056028B1 (es) * 1993-02-18 1995-04-01 Inia Procedimiento para la seleccion de oligonucleotidos para la amplificacion especifica de genomas altamente variables.
DE69434314T2 (de) * 1993-11-03 2006-03-30 Orchid Biosciences, Inc. Polymorphismus von mononukleotiden und ihre verwendung in der genanalyse
CA2182517C (en) * 1994-02-07 2001-08-21 Theo Nikiforov Ligase/polymerase-mediated primer extension of single nucleotide polymorphisms and its use in genetic analysis
US5888736A (en) * 1995-12-22 1999-03-30 Visible Genetics, Inc. Method, compositions and kit for detection and identification of microorganisms
US6479235B1 (en) 1994-09-30 2002-11-12 Promega Corporation Multiplex amplification of short tandem repeat loci
US7008771B1 (en) 1994-09-30 2006-03-07 Promega Corporation Multiplex amplification of short tandem repeat loci
US5753439A (en) * 1995-05-19 1998-05-19 Trustees Of Boston University Nucleic acid detection methods
US6127127A (en) * 1995-06-27 2000-10-03 The University Of North Carolina At Chapel Hill Monolayer and electrode for detecting a label-bearing target and method of use thereof
US6361951B1 (en) * 1995-06-27 2002-03-26 The University Of North Carolina At Chapel Hill Electrochemical detection of nucleic acid hybridization
US6180346B1 (en) 1995-06-27 2001-01-30 The Universtiy Of North Carolina At Chapel Hill Electropolymerizable film, and method of making and use thereof
US6387625B1 (en) 1995-06-27 2002-05-14 The University Of North Carolina At Chapel Hill Monolayer and electrode for detecting a label-bearing target and method of use thereof
US6132971A (en) * 1995-06-27 1998-10-27 The University Of North Carolina At Chapel Hill Microelectronic device
US5968745A (en) * 1995-06-27 1999-10-19 The University Of North Carolina At Chapel Hill Polymer-electrodes for detecting nucleic acid hybridization and method of use thereof
US6346387B1 (en) 1995-06-27 2002-02-12 Xanthon, Inc. Detection of binding reactions using labels detected by mediated catalytic electrochemistry
US6418382B2 (en) 1995-10-24 2002-07-09 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US5972693A (en) * 1995-10-24 1999-10-26 Curagen Corporation Apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US5871697A (en) 1995-10-24 1999-02-16 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US6413718B1 (en) 1996-05-01 2002-07-02 Visible Genetics Inc. Method for sequencing of nucleic acid polymers
US5871918A (en) * 1996-06-20 1999-02-16 The University Of North Carolina At Chapel Hill Electrochemical detection of nucleic acid hybridization
US6100030A (en) * 1997-01-10 2000-08-08 Pioneer Hi-Bred International, Inc. Use of selective DNA fragment amplification products for hybridization-based genetic fingerprinting, marker assisted selection, and high-throughput screening
US6475724B1 (en) 1997-01-28 2002-11-05 The Regents Of The University Of California Nucleic acids, kits, and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
US6171788B1 (en) 1997-01-28 2001-01-09 The Regents Of The University Of California Methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
US7138511B1 (en) 1997-01-28 2006-11-21 The Regents Of The University Of California Nucleic acids, kits and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
US5919626A (en) * 1997-06-06 1999-07-06 Orchid Bio Computer, Inc. Attachment of unmodified nucleic acids to silanized solid phase surfaces
US6544730B1 (en) 1997-10-27 2003-04-08 Prescott Deininger High density polymorphic genetic locus
US6238863B1 (en) 1998-02-04 2001-05-29 Promega Corporation Materials and methods for indentifying and analyzing intermediate tandem repeat DNA markers
WO1999066070A9 (en) * 1998-06-18 2000-04-06 Tomaras Constantine A dna biometric process used for identification
US20030207295A1 (en) * 1999-04-20 2003-11-06 Kevin Gunderson Detection of nucleic acid reactions on bead arrays
US20060275782A1 (en) 1999-04-20 2006-12-07 Illumina, Inc. Detection of nucleic acid reactions on bead arrays
GB9913556D0 (en) * 1999-06-11 1999-08-11 Zeneca Ltd Assays
WO2000079006A1 (en) * 1999-06-17 2000-12-28 Fred Hutchinson Cancer Research Center Oligonucleotide arrays for high resolution hla typing
US7611869B2 (en) 2000-02-07 2009-11-03 Illumina, Inc. Multiplexed methylation detection methods
US7955794B2 (en) 2000-09-21 2011-06-07 Illumina, Inc. Multiplex nucleic acid reactions
US8076063B2 (en) 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
EP1950305A1 (de) 2001-05-09 2008-07-30 Monsanto Technology, LLC Tyr-A-Gene und ihre Verwendung
WO2002097109A3 (en) * 2001-05-25 2003-05-08 Invitrogen Corp Compositions and methods for extension of nucleic acids
US7582420B2 (en) * 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US20030119000A1 (en) * 2001-11-05 2003-06-26 Jon Polansky Methods to screen and treat individuals with glaucoma or the propensity to develop glaucoma
US7222059B2 (en) * 2001-11-15 2007-05-22 Siemens Medical Solutions Diagnostics Electrophoretic trace simulator
US20040175704A1 (en) 2003-03-06 2004-09-09 Stratagene Compositions and methods for polynucleotide sequence detection
US7300755B1 (en) * 2003-05-12 2007-11-27 Fred Hutchinson Cancer Research Center Methods for haplotyping genomic DNA
WO2005102309A3 (en) * 2004-04-26 2006-05-18 Pierre Borgeat In vivo release of endogenous anti-microbial mediators by leukotriene b4 (ltb4) administration
US8163480B2 (en) * 2006-10-05 2012-04-24 Quest Diagnostics Investments Incorporated Nucleic acid size detection method

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3381518D1 (de) * 1982-01-22 1990-06-07 Cetus Corp Verfahren zur charakterisierung von hla und die darin benutzten cdns-testmittel.
DK105582A (da) * 1982-03-11 1983-09-12 Nordisk Insulinlab Fremgangsmaade til bestemmelse af humane hla-d(r) vaevstyper og gensonde til brug ved fremgangsmaaden
JPS59199000A (en) * 1983-02-28 1984-11-10 Akutagen Inc Determination of master system and establishment of indivisual hereditary identity
US4683194A (en) * 1984-05-29 1987-07-28 Cetus Corporation Method for detection of polymorphic restriction sites and nucleic acid sequences
EP0186271B1 (de) * 1984-11-12 1991-12-18 THE LISTER INSTITUTE OF PREVENTIVE MEDICINE Royal National Orthopaedic Hospital Methode zur Charakterisierung einer genomischen DNA-Probe
US4683202B1 (de) 1985-03-28 1990-11-27 Cetus Corp
US4801531A (en) * 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
CA1314811C (en) * 1985-06-14 1993-03-23 Gerald T. Nepom Methods for identifying alleles associated with increased risk of diabetes
JPH05501946A (de) * 1988-02-18 1993-04-15

Also Published As

Publication number Publication date Type
US5175082A (en) 1992-12-29 grant
RU1788970C (ru) 1993-01-15 grant
EP0238329A2 (de) 1987-09-23 application
JPH0630636B2 (ja) 1994-04-27 grant
CN87102927A (zh) 1988-04-27 application
FI871189A0 (fi) 1987-03-18 application
EP0238329B1 (de) 1994-04-27 grant
JPH05276948A (ja) 1993-10-26 application
JPS62282600A (en) 1987-12-08 application
DE3789679T2 (de) 1994-08-25 grant
FI871189A (fi) 1987-09-20 application
FI871189D0 (de) grant
DK140287A (da) 1987-09-20 application
EP0238329A3 (en) 1988-11-30 application
GB2188323B (en) 1990-06-06 grant
GB8706401D0 (en) 1987-04-23 grant
GB8606719D0 (en) 1986-04-23 grant
DK140287D0 (da) 1987-03-18 grant
JP1907803C (de) grant
GB2188323A (en) 1987-09-30 application

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee