DE3752148T2 - Echtzeitabtastvorrichtung in einem Elektrophoreseapparat zur DNS-Sequenzbestimmung - Google Patents

Echtzeitabtastvorrichtung in einem Elektrophoreseapparat zur DNS-Sequenzbestimmung

Info

Publication number
DE3752148T2
DE3752148T2 DE19873752148 DE3752148T DE3752148T2 DE 3752148 T2 DE3752148 T2 DE 3752148T2 DE 19873752148 DE19873752148 DE 19873752148 DE 3752148 T DE3752148 T DE 3752148T DE 3752148 T2 DE3752148 T2 DE 3752148T2
Authority
DE
Germany
Prior art keywords
real time
dna sequence
sequence determination
electrophoresis apparatus
time scanner
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE19873752148
Other languages
English (en)
Other versions
DE3752148D1 (de
Inventor
Michael W Hunkapillar
Charles R Connell
William J Mordan
John D Lytle
John A Bridgham
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems Inc
Original Assignee
Perkin Elmer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Perkin Elmer Corp filed Critical Perkin Elmer Corp
Application granted granted Critical
Publication of DE3752148D1 publication Critical patent/DE3752148D1/de
Publication of DE3752148T2 publication Critical patent/DE3752148T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44782—Apparatus specially adapted therefor of a plurality of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
DE19873752148 1987-06-09 1987-06-09 Echtzeitabtastvorrichtung in einem Elektrophoreseapparat zur DNS-Sequenzbestimmung Expired - Lifetime DE3752148T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19870305101 EP0294524B1 (de) 1987-06-09 1987-06-09 Echtzeitabtastvorrichtung in einem Elektrophoreseapparat zur DNS-Sequenzbestimmung

Publications (2)

Publication Number Publication Date
DE3752148D1 DE3752148D1 (de) 1998-01-08
DE3752148T2 true DE3752148T2 (de) 1998-09-17

Family

ID=8197939

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19873752148 Expired - Lifetime DE3752148T2 (de) 1987-06-09 1987-06-09 Echtzeitabtastvorrichtung in einem Elektrophoreseapparat zur DNS-Sequenzbestimmung

Country Status (2)

Country Link
EP (1) EP0294524B1 (de)
DE (1) DE3752148T2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5207880A (en) * 1984-03-29 1993-05-04 The Board Of Regents Of The University Of Nebraska DNA sequencing
US5230781A (en) * 1984-03-29 1993-07-27 Li-Cor, Inc. Sequencing near infrared and infrared fluorescence labeled DNA for detecting using laser diodes
JP2804038B2 (ja) * 1988-02-24 1998-09-24 株式会社日立製作所 塩基配列決定方法
JPH01224657A (ja) * 1988-03-04 1989-09-07 Hitachi Ltd 核酸の塩基配列決定装置
US4960999A (en) * 1989-02-13 1990-10-02 Kms Fusion, Inc. Scanning and storage of electrophoretic records
JP2901004B2 (ja) * 1989-04-12 1999-06-02 株式会社日立製作所 Ｄｎａの塩基配列決定法
JPH083481B2 (ja) * 1989-06-07 1996-01-17 日立ソフトウェアエンジニアリング株式会社 蛍光式電気泳動パターン読み取り装置
US5119316A (en) * 1990-06-29 1992-06-02 E. I. Du Pont De Nemours And Company Method for determining dna sequences
JP2814409B2 (ja) * 1990-11-30 1998-10-22 日立ソフトウェアエンジニアリング 株式会社 多色泳動パターン読み取り装置
DE4139211C2 (de) * 1990-11-30 1994-03-24 Hitachi Ltd Elektrophoresegerät
US5439578A (en) * 1993-06-03 1995-08-08 The Governors Of The University Of Alberta Multiple capillary biochemical analyzer
US5618398A (en) * 1995-12-12 1997-04-08 Visible Genetics Inc. Electrophoresis gels and gel holders having fiber spacers and method of making same
US5599434A (en) * 1995-12-12 1997-02-04 Visible Genetics Inc. Electrophoresis gels and gel holders having adhesive affixed fiber spacers and method of making same
US5776767A (en) * 1995-12-12 1998-07-07 Visible Genetics Inc. Virtual DNA sequencer
US6110683A (en) * 1999-01-08 2000-08-29 Commonwealth Biotechnologies, Inc. Automated DNA Sequencer loading dye which contains a lane tracking aid
DE19915137C2 (de) * 1999-03-26 2001-10-18 Michael Schaefer Verfahren zur Quantifizierung mehrerer Fluorochrome in einer mehrfach gefärbten Probe bei der Fluoreszenzmikroskopie und Verwendungen des Verfahrens
US6760668B1 (en) 2000-03-24 2004-07-06 Bayer Healthcare Llc Method for alignment of DNA sequences with enhanced accuracy and read length
US6690467B1 (en) * 2000-05-05 2004-02-10 Pe Corporation Optical system and method for optically analyzing light from a sample
US7222059B2 (en) 2001-11-15 2007-05-22 Siemens Medical Solutions Diagnostics Electrophoretic trace simulator
DE102005022880B4 (de) * 2005-05-18 2010-12-30 Olympus Soft Imaging Solutions Gmbh Trennung spektral oder farblich überlagerter Bildbeiträge in einem Mehrfarbbild, insbesondere in transmissionsmikroskopischen Mehrfarbbildern

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2417305A1 (de) * 1973-04-09 1974-10-24 Joyce Loebl Ltd Abtastmechanismus
US4130824A (en) * 1977-05-24 1978-12-19 Corning Glass Works Recording analyzer for electrophoretic samples
JPS55164336A (en) * 1979-06-08 1980-12-22 Olympus Optical Co Ltd Inspecting material detecting method
CA1258611A (en) * 1984-01-16 1989-08-22 Lloyd M. Smith Method of dna sequencing
US4729947A (en) * 1984-03-29 1988-03-08 The Board Of Regents Of The University Of Nebraska DNA sequencing
GB8513538D0 (en) * 1985-05-29 1985-07-03 Mackay C D Electrophoresis
DE3620235A1 (de) * 1985-06-17 1986-12-18 EG & G., Inc., Wellesley, Mass. System zur bestimmung der groessen von biologischen makromolekuelen

Also Published As

Publication number Publication date
EP0294524B1 (de) 1997-11-26
DE3752148D1 (de) 1998-01-08
EP0294524A1 (de) 1988-12-14

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication of lapse of patent is to be deleted
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: APPLERA CORP., FOSTER CITY, CALIF., US