DE3650610T2 - Kapillardurchflussgerät - Google Patents

Kapillardurchflussgerät

Info

Publication number
DE3650610T2
DE3650610T2 DE19863650610 DE3650610T DE3650610T2 DE 3650610 T2 DE3650610 T2 DE 3650610T2 DE 19863650610 DE19863650610 DE 19863650610 DE 3650610 T DE3650610 T DE 3650610T DE 3650610 T2 DE3650610 T2 DE 3650610T2
Authority
DE
Germany
Prior art keywords
flow device
capillary flow
capillary
flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE19863650610
Other languages
English (en)
Other versions
DE3650610D1 (de
Inventor
Jimmy D Allen
Michael E Cobb
Robert S Hillman
Laura J Winfrey
Vladimir E Ostoich
Ian Gibbons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics Corp
Original Assignee
Boehringer Mannheim Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Corp filed Critical Boehringer Mannheim Corp
Publication of DE3650610D1 publication Critical patent/DE3650610D1/de
Application granted granted Critical
Publication of DE3650610T2 publication Critical patent/DE3650610T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/50—Mixing liquids with solids
    • B01F23/56—Mixing liquids with solids by introducing solids in liquids, e.g. dispersing or dissolving
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/431—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor
    • B01F25/4316—Straight mixing tubes with baffles or obstructions that do not cause substantial pressure drop; Baffles therefor the baffles being flat pieces of material, e.g. intermeshing, fixed to the wall or fixed on a central rod
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/433—Mixing tubes wherein the shape of the tube influences the mixing, e.g. mixing tubes with varying cross-section or provided with inwardly extending profiles
    • B01F25/4338—Mixers with a succession of converging-diverging cross-sections, i.e. undulating cross-section
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/71—Feed mechanisms
    • B01F35/717—Feed mechanisms characterised by the means for feeding the components to the mixer
    • B01F35/7172—Feed mechanisms characterised by the means for feeding the components to the mixer using capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/08—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using ultrasonic vibrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/01—General aspects dealing with the joint area or with the area to be joined
    • B29C66/05—Particular design of joint configurations
    • B29C66/302—Particular design of joint configurations the area to be joined comprising melt initiators
    • B29C66/3022—Particular design of joint configurations the area to be joined comprising melt initiators said melt initiators being integral with at least one of the parts to be joined
    • B29C66/30223—Particular design of joint configurations the area to be joined comprising melt initiators said melt initiators being integral with at least one of the parts to be joined said melt initiators being rib-like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/54—Joining several hollow-preforms, e.g. half-shells, to form hollow articles, e.g. for making balls, containers; Joining several hollow-preforms, e.g. half-cylinders, to form tubular articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/70—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material
    • B29C66/71—General aspects of processes or apparatus for joining preformed parts characterised by the composition, physical properties or the structure of the material of the parts to be joined; Joining with non-plastics material characterised by the composition of the plastics material of the parts to be joined
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/82—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a precipitate or turbidity
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F21/00—Dissolving
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0694—Valves, specific forms thereof vents used to stop and induce flow, backpressure valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C59/00—Surface shaping of articles, e.g. embossing; Apparatus therefor
    • B29C59/16—Surface shaping of articles, e.g. embossing; Apparatus therefor by wave energy or particle radiation, e.g. infrared heating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/48—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor using adhesives, i.e. using supplementary joining material; solvent bonding
    • B29C65/4895—Solvent bonding, i.e. the surfaces of the parts to be joined being treated with solvents, swelling or softening agents, without adhesives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/90—Measuring or controlling the joining process
    • B29C66/95—Measuring or controlling the joining process by measuring or controlling specific variables not covered by groups B29C66/91 - B29C66/94
    • B29C66/951—Measuring or controlling the joining process by measuring or controlling specific variables not covered by groups B29C66/91 - B29C66/94 by measuring or controlling the vibration frequency and/or the vibration amplitude of vibrating joining tools, e.g. of ultrasonic welding tools
    • B29C66/9513—Measuring or controlling the joining process by measuring or controlling specific variables not covered by groups B29C66/91 - B29C66/94 by measuring or controlling the vibration frequency and/or the vibration amplitude of vibrating joining tools, e.g. of ultrasonic welding tools characterised by specific vibration frequency values or ranges
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2055/00—Use of specific polymers obtained by polymerisation reactions only involving carbon-to-carbon unsaturated bonds, not provided for in a single one of main groups B29K2023/00 - B29K2049/00, e.g. having a vinyl group, as moulding material
    • B29K2055/02—ABS polymers, i.e. acrylonitrile-butadiene-styrene polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/756—Microarticles, nanoarticles
    • G01N2015/1016—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00514—Stationary mixing elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S366/00—Agitating
    • Y10S366/03—Micromixers: variable geometry from the pathway influences mixing/agitation of non-laminar fluid flow
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
DE19863650610 1985-08-05 1986-07-24 Kapillardurchflussgerät Expired - Lifetime DE3650610T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76274885A 1985-08-05 1985-08-05
US06/880,793 US4756884A (en) 1985-08-05 1986-07-01 Capillary flow device

Publications (2)

Publication Number Publication Date
DE3650610D1 DE3650610D1 (de) 1997-05-15
DE3650610T2 true DE3650610T2 (de) 1997-09-25

Family

ID=27117182

Family Applications (4)

Application Number Title Priority Date Filing Date
DE19863689812 Expired - Lifetime DE3689812T2 (de) 1985-08-05 1986-07-24 Kapillardurchflussgerät.
DE19863650574 Expired - Lifetime DE3650574T2 (de) 1985-08-05 1986-07-24 Kapillardurchflussgerät
DE19863650530 Expired - Lifetime DE3650530T2 (de) 1985-08-05 1986-07-24 Qualitätssicherunggerät zur Verwendung in einem analytischen Instrument
DE19863650610 Expired - Lifetime DE3650610T2 (de) 1985-08-05 1986-07-24 Kapillardurchflussgerät

Family Applications Before (3)

Application Number Title Priority Date Filing Date
DE19863689812 Expired - Lifetime DE3689812T2 (de) 1985-08-05 1986-07-24 Kapillardurchflussgerät.
DE19863650574 Expired - Lifetime DE3650574T2 (de) 1985-08-05 1986-07-24 Kapillardurchflussgerät
DE19863650530 Expired - Lifetime DE3650530T2 (de) 1985-08-05 1986-07-24 Qualitätssicherunggerät zur Verwendung in einem analytischen Instrument

Country Status (6)

Country Link
US (1) US4756884A (de)
EP (4) EP0212314B1 (de)
JP (5) JPH0658373B2 (de)
AU (1) AU593001B2 (de)
CA (1) CA1275231C (de)
DE (4) DE3689812T2 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10148210A1 (de) * 2001-09-28 2003-04-24 Ibidi Gmbh Flusskammer
US7517499B2 (en) 2001-09-28 2009-04-14 Ibidi Gmbh Flow chamber

Families Citing this family (455)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5140161A (en) * 1985-08-05 1992-08-18 Biotrack Capillary flow device
US5144139A (en) * 1985-08-05 1992-09-01 Biotrack, Inc. Capillary flow device
US5164598A (en) * 1985-08-05 1992-11-17 Biotrack Capillary flow device
US4948961A (en) * 1985-08-05 1990-08-14 Biotrack, Inc. Capillary flow device
US4753776A (en) * 1986-10-29 1988-06-28 Biotrack, Inc. Blood separation device comprising a filter and a capillary flow pathway exiting the filter
US4775515A (en) * 1986-11-18 1988-10-04 Cottingham Hugh V Agglutinographic slide
DE3706718A1 (de) * 1987-03-02 1988-09-15 Boehringer Mannheim Gmbh Vorrichtung zur durchfuehrung einer heterogenen reaktion
US4849340A (en) * 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
US5110727A (en) * 1987-04-03 1992-05-05 Cardiovascular Diagnostics, Inc. Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles
US5006464A (en) * 1987-10-01 1991-04-09 E-Y Laboratories, Inc. Directed flow diagnostic device and method
DK163194C (da) * 1988-12-22 1992-06-22 Radiometer As Fremgangsmaade ved fotometrisk in vitro bestemmelse af en blodgasparameter i en blodproeve
EP0321736B1 (de) * 1987-12-23 1994-06-01 Abbott Laboratories Vorrichtung zur Agglutinierungsreaktion
DE3814585A1 (de) * 1988-04-29 1989-11-09 Hoffmann La Roche Testelement fuer agglutinationsuntersuchungen, verfahren zu seiner herstellung und dessen verwendung
US5096669A (en) * 1988-09-15 1992-03-17 I-Stat Corporation Disposable sensing device for real time fluid analysis
US4952055A (en) * 1988-10-03 1990-08-28 Wyatt Technology Corporation Differential refractometer
US5057279A (en) * 1988-10-13 1991-10-15 The United States Of America As Represented By The Secretary Of The Navy Pressurized membrane chemical sensor
AU609332B2 (en) * 1988-11-09 1991-04-26 Biotrack, Inc. Method and composition of stabilizing and solubilizing latex reagents
US6645758B1 (en) 1989-02-03 2003-11-11 Johnson & Johnson Clinical Diagnostics, Inc. Containment cuvette for PCR and method of use
US5229297A (en) * 1989-02-03 1993-07-20 Eastman Kodak Company Containment cuvette for PCR and method of use
IE69047B1 (en) * 1989-03-23 1996-08-07 Gary Harold Gregory Hen Thorpe Liquid transfer devices
US5073216A (en) * 1989-04-07 1991-12-17 Abbott Laboratories Method of ultrasonically cutting fibrous materials and device therefrom
US5104813A (en) * 1989-04-13 1992-04-14 Biotrack, Inc. Dilution and mixing cartridge
US5039617A (en) * 1989-04-20 1991-08-13 Biotrack, Inc. Capillary flow device and method for measuring activated partial thromboplastin time
AU5247790A (en) * 1989-04-20 1990-10-25 Biotrack, Inc. Capillary flow device and reading instrument
US5286454A (en) * 1989-04-26 1994-02-15 Nilsson Sven Erik Cuvette
SE465742B (sv) * 1989-04-26 1991-10-21 Migrata Uk Ltd Kyvett foer upptagning foer minst ett fluidum
EP0397424A3 (de) * 1989-05-08 1991-08-21 Biotrack, Inc. Mehrfachanalysesystem
US5234813A (en) * 1989-05-17 1993-08-10 Actimed Laboratories, Inc. Method and device for metering of fluid samples and detection of analytes therein
US5087556A (en) * 1989-05-17 1992-02-11 Actimed Laboratories, Inc. Method for quantitative analysis of body fluid constituents
US5207988A (en) * 1989-07-06 1993-05-04 The Cleveland Clinic Foundation Apparatus for detecting and quantifying clot lysis and establishing optimum medication and dosages
US5225163A (en) * 1989-08-18 1993-07-06 Angenics, Inc. Reaction apparatus employing gravitational flow
WO1991002589A1 (en) * 1989-08-18 1991-03-07 Cambridge Bioscience Corporation Reaction apparatus and method employing gravitational flow
US5030005A (en) * 1989-11-29 1991-07-09 Akzo N.V. Liquid crystal device for calibration and testing of optical instruments
US5066465A (en) * 1989-12-27 1991-11-19 Olympus Optical Co., Ltd. Reaction apparatus
US5188968A (en) * 1989-12-28 1993-02-23 Olympus Optical Co., Ltd. Method and reaction kit for agglutination detection
US6176962B1 (en) 1990-02-28 2001-01-23 Aclara Biosciences, Inc. Methods for fabricating enclosed microchannel structures
US5411894A (en) * 1990-03-20 1995-05-02 Abbott Laboratories Method of using tissue and cell adhesive preparations for biological test systems
GB9009000D0 (en) * 1990-04-21 1990-06-20 Bovril Ltd Novel process
WO1991018276A1 (en) * 1990-05-22 1991-11-28 Kelly Kenneth A Microassay strip device for immunoassay
TW221493B (de) * 1990-07-10 1994-03-01 Cardiovascular Diagnostics Inc
US5124661A (en) * 1990-07-23 1992-06-23 I-Stat Corporation Reusable test unit for simulating electrochemical sensor signals for quality assurance of portable blood analyzer instruments
US5208163A (en) * 1990-08-06 1993-05-04 Miles Inc. Self-metering fluid analysis device
TW233341B (de) * 1990-08-23 1994-11-01 Abbott Lab
ATE153138T1 (de) * 1990-09-26 1997-05-15 Akers Lab Inc Verbessertes bestimmungsverfahren für liganden
CA2062027C (en) * 1991-03-04 1998-05-19 William Aldrich Liquid control system for diagnostic cartridges used in analytical instruments
CA2062338A1 (en) * 1991-03-15 1992-09-16 Zia Yassinzadeh Electronic control cartridge and method of simulating light transmission patterns
US5726010A (en) * 1991-07-31 1998-03-10 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
US6007999A (en) * 1991-07-31 1999-12-28 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
US7297313B1 (en) 1991-08-31 2007-11-20 The Regents Of The University Of California Microfabricated reactor, process for manufacturing the reactor, and method of amplification
US5540888A (en) * 1991-11-11 1996-07-30 British Technology Group Limited Liquid transfer assay devices
US5430542A (en) * 1992-04-10 1995-07-04 Avox Systems, Inc. Disposable optical cuvette
US5222808A (en) * 1992-04-10 1993-06-29 Biotrack, Inc. Capillary mixing device
US5223219A (en) * 1992-04-10 1993-06-29 Biotrack, Inc. Analytical cartridge and system for detecting analytes in liquid samples
US5580744A (en) * 1992-04-27 1996-12-03 Avocet Medical, Inc. Test article and method for performing blood coagulation assays
AU4287593A (en) * 1992-04-27 1993-11-29 Avocet Medical, Inc. Test article and method for performing blood coagulation assays
US5498392A (en) * 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
ATE140025T1 (de) * 1992-05-01 1996-07-15 Univ Pennsylvania Mikrohergestellte vorrichtungen zum handhaben von sperma
US6953676B1 (en) 1992-05-01 2005-10-11 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
US5637469A (en) * 1992-05-01 1997-06-10 Trustees Of The University Of Pennsylvania Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems
US5726026A (en) * 1992-05-01 1998-03-10 Trustees Of The University Of Pennsylvania Mesoscale sample preparation device and systems for determination and processing of analytes
US5304487A (en) * 1992-05-01 1994-04-19 Trustees Of The University Of Pennsylvania Fluid handling in mesoscale analytical devices
US5587128A (en) 1992-05-01 1996-12-24 The Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification devices
US5486335A (en) * 1992-05-01 1996-01-23 Trustees Of The University Of Pennsylvania Analysis based on flow restriction
US6019944A (en) * 1992-05-21 2000-02-01 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US7524456B1 (en) 1992-05-21 2009-04-28 Biosite Incorporated Diagnostic devices for the controlled movement of reagents without membranes
US6156270A (en) 1992-05-21 2000-12-05 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US5458852A (en) * 1992-05-21 1995-10-17 Biosite Diagnostics, Inc. Diagnostic devices for the controlled movement of reagents without membranes
US6905882B2 (en) * 1992-05-21 2005-06-14 Biosite, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US6767510B1 (en) 1992-05-21 2004-07-27 Biosite, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
US5639423A (en) * 1992-08-31 1997-06-17 The Regents Of The University Of Calfornia Microfabricated reactor
JPH08501392A (ja) * 1992-09-14 1996-02-13 パーデュー リサーチ ファウンデーション 電気泳動法による化学分析
US5500187A (en) * 1992-12-08 1996-03-19 Westinghouse Electric Corporation Disposable optical agglutination assay device and method for use
US5302348A (en) * 1992-12-10 1994-04-12 Itc Corporation Blood coagulation time test apparatus and method
DE69410084T2 (de) * 1993-02-03 1999-01-21 Histaggen Inc Automatisiertes histo-zytochemisches gerät und einkapselungssystem zum behandeln von biologischem material
US5670329A (en) * 1993-05-28 1997-09-23 Cardiovascular Diagnostics, Inc. Method and analytical system for performing fibrinogen assays accurately, rapidly and simply using a rotating magnetic field
EP0720439A4 (de) * 1993-08-31 1997-09-24 Boehringer Mannheim Corp Stromversorgungssteuerung und kontrolle für medizinisches instrument
US5526111A (en) * 1993-08-31 1996-06-11 Boehringer Mannheim Corporation Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control
US5522255A (en) 1993-08-31 1996-06-04 Boehringer Mannheim Corporation Fluid dose, flow and coagulation sensor for medical instrument
US5841023A (en) * 1993-08-31 1998-11-24 Boehringer Mannheim Corporation Magnet for medical instrument
GB9320850D0 (en) * 1993-10-09 1993-12-01 Terwee Thomas H M Monitoring the concentration of a substance or a group of substances in a body fluid of a human or an animal
US5447440A (en) * 1993-10-28 1995-09-05 I-Stat Corporation Apparatus for assaying viscosity changes in fluid samples and method of conducting same
US5478751A (en) * 1993-12-29 1995-12-26 Abbott Laboratories Self-venting immunodiagnositic devices and methods of performing assays
US5840573A (en) * 1994-02-01 1998-11-24 Fields; Robert E. Molecular analyzer and method of use
CA2143365A1 (en) * 1994-03-14 1995-09-15 Hugh V. Cottingham Nucleic acid amplification method and apparatus
GB9409333D0 (en) * 1994-05-10 1994-06-29 Palmer Richard F Analytical method and device for use therein
FR2721714B1 (fr) * 1994-06-23 1996-09-06 Karim Boulhimez Dispositif d'évaluation de l'activité coagulante sanguine d'un échantillon biologique, jetable après usage unique, et procédé de mise en Óoeuvre.
US5488816A (en) * 1994-07-21 1996-02-06 Boehringer Mannheim Corporation Method and apparatus for manufacturing a coagulation assay device in a continuous manner
CA2156226C (en) * 1994-08-25 1999-02-23 Takayuki Taguchi Biological fluid analyzing device and method
US5627041A (en) * 1994-09-02 1997-05-06 Biometric Imaging, Inc. Disposable cartridge for an assay of a biological sample
US5504011A (en) * 1994-10-21 1996-04-02 International Technidyne Corporation Portable test apparatus and associated method of performing a blood coagulation test
WO1996015576A1 (en) * 1994-11-10 1996-05-23 David Sarnoff Research Center, Inc. Liquid distribution system
US5585069A (en) * 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
US5603351A (en) * 1995-06-07 1997-02-18 David Sarnoff Research Center, Inc. Method and system for inhibiting cross-contamination in fluids of combinatorial chemistry device
US5731212A (en) * 1994-12-20 1998-03-24 International Technidyne Corporation Test apparatus and method for testing cuvette accommodated samples
SE504193C2 (sv) * 1995-04-21 1996-12-02 Hemocue Ab Kapillär mikrokyvett
US6454945B1 (en) 1995-06-16 2002-09-24 University Of Washington Microfabricated devices and methods
US5716852A (en) * 1996-03-29 1998-02-10 University Of Washington Microfabricated diffusion-based chemical sensor
NZ299724A (en) * 1995-11-15 1997-03-24 Nihon Mediphysics Co Ltd Analysis of liquid using diminished intensity of a reflected beam, use in analysing trace samples and apparatus therefor
JP4044163B2 (ja) * 1995-11-15 2008-02-06 アークレイ株式会社 液体検知方法および器具
US5981294A (en) * 1995-11-29 1999-11-09 Metrika, Inc. Device for blood separation in a diagnostic device
US5736404A (en) * 1995-12-27 1998-04-07 Zia Yassinzadeh Flow detection appartus and method
GB2310493B (en) * 1996-02-26 2000-08-02 Unilever Plc Determination of the characteristics of fluid
US6541213B1 (en) 1996-03-29 2003-04-01 University Of Washington Microscale diffusion immunoassay
US20030211507A1 (en) * 1996-03-29 2003-11-13 Anson Hatch Microscale diffusion immunoassay in hydrogels
US5948684A (en) * 1997-03-31 1999-09-07 University Of Washington Simultaneous analyte determination and reference balancing in reference T-sensor devices
US5942443A (en) * 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
US5968839A (en) * 1996-05-13 1999-10-19 Metrika, Inc. Method and device producing a predetermined distribution of detectable change in assays
EP0907412B1 (de) 1996-06-28 2008-08-27 Caliper Life Sciences, Inc. Hochdurchsatz-screening-testsystem mittels mikrofluidischer vorrichtungen
US6143248A (en) * 1996-08-12 2000-11-07 Gamera Bioscience Corp. Capillary microvalve
US5945345A (en) * 1996-08-27 1999-08-31 Metrika, Inc. Device for preventing assay interference using silver or lead to remove the interferant
US6113855A (en) * 1996-11-15 2000-09-05 Biosite Diagnostics, Inc. Devices comprising multiple capillarity inducing surfaces
US20050101032A1 (en) * 1997-02-10 2005-05-12 Metrika, Inc. Assay device, composition, and method of optimizing assay sensitivity
AU6681298A (en) * 1997-03-05 1998-09-22 Diametrics Method and apparatus for measurement of whole blood coagulation parameters
EP0977032B1 (de) * 1997-03-12 2009-07-22 Kyoto Daiichi Kagaku Co., Ltd. Analyseinstrument zum testen von flüssigproben
GB9705667D0 (en) * 1997-03-19 1997-05-07 Jackson James R Diagnostic and analytical devices
JP3739537B2 (ja) * 1997-03-26 2006-01-25 大日本印刷株式会社 光学的分析装置用測定チップ
US6093330A (en) * 1997-06-02 2000-07-25 Cornell Research Foundation, Inc. Microfabrication process for enclosed microstructures
AU7831798A (en) * 1997-06-09 1998-12-30 Guava Technologies, Inc. Method and apparatus for detecting microparticles in fluid samples
US6613512B1 (en) 1997-06-09 2003-09-02 Caliper Technologies Corp. Apparatus and method for correcting for variable velocity in microfluidic systems
US5992820A (en) * 1997-11-19 1999-11-30 Sarnoff Corporation Flow control in microfluidics devices by controlled bubble formation
JP3896435B2 (ja) * 1997-12-17 2007-03-22 アークレイ株式会社 センサおよびセンサ集合体
GB9800263D0 (en) * 1998-01-08 1998-03-04 Bio Diagnostics Ltd A device for testing liquids
SE9800070D0 (sv) * 1998-01-14 1998-01-14 Hemocue Ab Blandningsmetod
SE520341C2 (sv) * 1998-01-14 2003-06-24 Hemocue Ab Metod och förfarande för blandning i ett tunt vätskeskick
WO1999046591A2 (en) * 1998-03-10 1999-09-16 Strategic Diagnostics, Inc. Integrated assay device and methods of production and use
CA2324244C (en) * 1998-03-17 2008-01-08 Cepheid Device for analyzing a sample
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
DE19815684A1 (de) 1998-04-08 1999-10-14 Roche Diagnostics Gmbh Verfahren zur Herstellung von analytischen Hilfsmitteln
GB9808836D0 (en) * 1998-04-27 1998-06-24 Amersham Pharm Biotech Uk Ltd Microfabricated apparatus for cell based assays
GB9809943D0 (en) * 1998-05-08 1998-07-08 Amersham Pharm Biotech Ab Microfluidic device
US6180536B1 (en) 1998-06-04 2001-01-30 Cornell Research Foundation, Inc. Suspended moving channels and channel actuators for microfluidic applications and method for making
GB2339615B (en) * 1998-07-14 2001-02-07 Cozart Bioscience Ltd Screening device and method of screening an immunoassay test
US6521182B1 (en) * 1998-07-20 2003-02-18 Lifescan, Inc. Fluidic device for medical diagnostics
US6830934B1 (en) 1999-06-15 2004-12-14 Lifescan, Inc. Microdroplet dispensing for a medical diagnostic device
US6087182A (en) * 1998-08-27 2000-07-11 Abbott Laboratories Reagentless analysis of biological samples
US6601613B2 (en) 1998-10-13 2003-08-05 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
EP1125129A1 (de) * 1998-10-13 2001-08-22 Biomicro Systems, Inc. Komponenten eines flüssigkeitskreislaufes, basierend auf passiven flüssigkeitsdynamiken
US6637463B1 (en) 1998-10-13 2003-10-28 Biomicro Systems, Inc. Multi-channel microfluidic system design with balanced fluid flow distribution
US6591852B1 (en) 1998-10-13 2003-07-15 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
AU766434B2 (en) 1998-11-05 2003-10-16 Chemometec A/S A method for the assessment of particles and a system and a device for use in the method
US6597439B1 (en) 1999-02-12 2003-07-22 Fuji Photo Film Co., Ltd. Method and apparatus for measurement of light from illuminated specimen eliminating influence of background light
US6585939B1 (en) * 1999-02-26 2003-07-01 Orchid Biosciences, Inc. Microstructures for use in biological assays and reactions
FR2790684B1 (fr) * 1999-03-09 2001-05-11 Biomerieux Sa Appareil permettant en son sein le transfert de liquides par capillarite
DE19912365A1 (de) 1999-03-19 2000-09-21 Roche Diagnostics Gmbh Mehrschichtiges analytisches Hilfsmittel
US6183979B1 (en) * 1999-03-24 2001-02-06 International Technidyne Corporation Preparation of dried synthetic prothrombin time reagents
US6451610B1 (en) * 1999-04-14 2002-09-17 International Technidyne Corporation Method and apparatus for coagulation based assays
US6733985B1 (en) * 1999-05-19 2004-05-11 International Technidyne Corporation Preparation of stable liquid and dried synthetic prothrombin time reagents
US6485690B1 (en) 1999-05-27 2002-11-26 Orchid Biosciences, Inc. Multiple fluid sample processor and system
DE19919608A1 (de) * 1999-05-27 2000-11-30 Roche Diagnostics Gmbh Probenträger für die IR-Spetktroskopie von Probenflüssigkeiten
ES2294389T3 (es) † 1999-07-07 2008-04-01 3M Innovative Properties Company Articulo microfluidico.
GB9917325D0 (en) 1999-07-23 1999-09-22 Clinical Diagnostic Chemicals Apparatus for collecting a liquid sample
ATE364843T1 (de) * 1999-08-11 2007-07-15 Asahi Chemical Ind Analysenkassette und flüssigkeitsförderkontroller
AU6933900A (en) 1999-09-03 2001-04-10 Roche Diagnostics Corporation Method, reagent and test cartridge for determining clotting time
US6319719B1 (en) * 1999-10-28 2001-11-20 Roche Diagnostics Corporation Capillary hematocrit separation structure and method
US6750053B1 (en) 1999-11-15 2004-06-15 I-Stat Corporation Apparatus and method for assaying coagulation in fluid samples
WO2001044493A2 (en) * 1999-12-15 2001-06-21 Pentapharm Ag Hematological assay and reagent
US6451264B1 (en) 2000-01-28 2002-09-17 Roche Diagnostics Corporation Fluid flow control in curved capillary channels
US6406672B1 (en) 2000-01-28 2002-06-18 Roche Diagnostics Plasma retention structure providing internal flow
US6438498B1 (en) 2000-02-10 2002-08-20 I-Stat Corporation System, method and computer implemented process for assaying coagulation in fluid samples
WO2001062887A1 (en) * 2000-02-23 2001-08-30 Zyomyx, Inc. Chips having elevated sample surfaces
US7485454B1 (en) * 2000-03-10 2009-02-03 Bioprocessors Corp. Microreactor
JP4733331B2 (ja) * 2000-03-14 2011-07-27 マイクロニックス、インコーポレーテッド マイクロ流動体分析用デバイス
US6571651B1 (en) 2000-03-27 2003-06-03 Lifescan, Inc. Method of preventing short sampling of a capillary or wicking fill device
AU2001251340A1 (en) * 2000-04-06 2001-10-23 Caliper Technologies Corp. Microfluidic devices and systems incorporating cover layers
US6669831B2 (en) * 2000-05-11 2003-12-30 Caliper Technologies Corp. Microfluidic devices and methods to regulate hydrodynamic and electrical resistance utilizing bulk viscosity enhancers
WO2001088525A1 (en) * 2000-05-12 2001-11-22 University Of Cincinnati Structurally programmable microfluidic systems
RU2278612C2 (ru) * 2000-07-14 2006-06-27 Лайфскен, Инк. Иммуносенсор
JP4384344B2 (ja) * 2000-08-09 2009-12-16 拓之 今野 レーザ反射光による粒状斑点模様を利用した血液凝固時間測定方法とその装置
US6448024B1 (en) 2000-10-03 2002-09-10 Roche Diagnostics Corporation Method, reagent, cartridge, and device for determining fibrinogen
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
GB0030929D0 (en) * 2000-12-19 2001-01-31 Inverness Medical Ltd Analyte measurement
US6558528B1 (en) * 2000-12-20 2003-05-06 Lifescan, Inc. Electrochemical test strip cards that include an integral dessicant
US20020108860A1 (en) * 2001-01-15 2002-08-15 Staats Sau Lan Tang Fabrication of polymeric microfluidic devices
US6925390B2 (en) * 2001-01-15 2005-08-02 Sau Lan Tang Staats Customized microfluidic device design, ordering, and manufacturing
US20020100714A1 (en) * 2001-01-31 2002-08-01 Sau Lan Tang Staats Microfluidic devices
WO2002063288A1 (en) * 2001-01-31 2002-08-15 Sau Lan Tang Staats Microfluidic devices
EP1409712A4 (de) * 2001-04-10 2008-05-14 Bioprocessors Corp Mikrofermentervorrichtung und screeningverfahren auf zellbasis
US6759009B2 (en) 2001-05-04 2004-07-06 Portascience Incorporated Method and device for clotting time assay
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
WO2002100254A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
CA2448902C (en) 2001-06-12 2010-09-07 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
ES2352998T3 (es) 2001-06-12 2011-02-24 Pelikan Technologies Inc. Accionador eléctrico de lanceta.
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
GB2378242B (en) * 2001-06-26 2005-08-03 Univ Hull Depth and concentration estimation
US7776608B2 (en) * 2001-07-09 2010-08-17 Bayer Healthcare Llc Volume meter testing device and method of use
US20060062696A1 (en) * 2001-07-27 2006-03-23 Caliper Life Sciences, Inc. Optimized high throughput analytical systems
US7060227B2 (en) * 2001-08-06 2006-06-13 Sau Lan Tang Staats Microfluidic devices with raised walls
US20030040129A1 (en) * 2001-08-20 2003-02-27 Shah Haresh P. Binding assays using magnetically immobilized arrays
DE10140699A1 (de) * 2001-08-24 2003-03-13 Roche Diagnostics Gmbh Anordnung und Verfahren zur Untersuchung der Fließfähigkeit einer physiologischen Flüssigprobe
US6919058B2 (en) * 2001-08-28 2005-07-19 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
FR2829286B1 (fr) * 2001-09-03 2008-04-04 Ge Med Sys Global Tech Co Llc Dispositif et procede d'emission de rayons x
EP1296133A1 (de) * 2001-09-21 2003-03-26 Jean Brunner Miniaturvorrichtung zum Transport und zur Analyse flüssiger Proben und Herstellungsverfahren dafür
US7537731B2 (en) * 2001-10-19 2009-05-26 Panasonic Corporation Specific binding analysis device
US20040028559A1 (en) * 2001-11-06 2004-02-12 Peter Schuck Sample delivery system with laminar mixing for microvolume biosensing
US7061593B2 (en) * 2001-11-08 2006-06-13 Optiscan Biomedical Corp. Device and method for in vitro determination of analyte concentrations within body fluids
US6989891B2 (en) 2001-11-08 2006-01-24 Optiscan Biomedical Corporation Device and method for in vitro determination of analyte concentrations within body fluids
US6997343B2 (en) 2001-11-14 2006-02-14 Hypoguard Limited Sensor dispensing device
US6800849B2 (en) * 2001-12-19 2004-10-05 Sau Lan Tang Staats Microfluidic array devices and methods of manufacture and uses thereof
US6864480B2 (en) * 2001-12-19 2005-03-08 Sau Lan Tang Staats Interface members and holders for microfluidic array devices
US6877892B2 (en) * 2002-01-11 2005-04-12 Nanostream, Inc. Multi-stream microfluidic aperture mixers
US20040131500A1 (en) * 2002-01-18 2004-07-08 Chow Herbert S. Device and method for evaluating platelets
JP2004003976A (ja) * 2002-04-05 2004-01-08 Matsushita Electric Ind Co Ltd 特異結合分析方法およびこれに用いるデバイス
EP1352688A1 (de) 2002-04-09 2003-10-15 Jean Brunner Miniaturisierter Probenhalter
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
JP4095886B2 (ja) * 2002-05-08 2008-06-04 株式会社日立ハイテクノロジーズ 化学分析装置及び遺伝子診断装置
US7198759B2 (en) * 2002-07-26 2007-04-03 Applera Corporation Microfluidic devices, methods, and systems
JP2004069397A (ja) * 2002-08-02 2004-03-04 Nec Corp 分析チップおよび分析装置
KR100480338B1 (ko) * 2002-08-08 2005-03-30 한국전자통신연구원 극소량의 유체제어를 위한 미세 유체제어소자
US7604775B2 (en) 2002-08-12 2009-10-20 Bayer Healthcare Llc Fluid collecting and monitoring device
GB0220338D0 (en) * 2002-09-02 2002-10-09 Secretary Trade Ind Brit Production of variable concentration fluid mixtures
KR100444751B1 (ko) * 2002-11-11 2004-08-16 한국전자통신연구원 표면장력에 의한 유체제어 소자
KR100471377B1 (ko) * 2002-11-20 2005-03-11 한국전자통신연구원 표면장력으로 제어되는 미세유체소자
US7094354B2 (en) * 2002-12-19 2006-08-22 Bayer Healthcare Llc Method and apparatus for separation of particles in a microfluidic device
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US20040132168A1 (en) * 2003-01-06 2004-07-08 Peter Rule Sample element for reagentless whole blood glucose meter
US20040132167A1 (en) * 2003-01-06 2004-07-08 Peter Rule Cartridge lance
US6983177B2 (en) * 2003-01-06 2006-01-03 Optiscan Biomedical Corporation Layered spectroscopic sample element with microporous membrane
ATE449962T1 (de) * 2003-02-05 2009-12-15 Gen Hospital Corp System auf mikrochipbasis zur hiv-diagnostik
US20040176704A1 (en) * 2003-03-04 2004-09-09 Stevens Timothy A Collection device adapted to accept cartridge for point of care system
US20040176705A1 (en) * 2003-03-04 2004-09-09 Stevens Timothy A. Cartridge having an integrated collection element for point of care system
GB0306098D0 (en) * 2003-03-18 2003-04-23 Platform Diagnostics Group Ltd Sample testing device
EP1618389A1 (de) * 2003-04-15 2006-01-25 Optiscan Biomedical Corporation Probenelementqualifizierung
EP1619994A4 (de) * 2003-04-16 2009-03-11 Univ Drexel Akustischer blutanalysator zur beurteilung von bluteigenschaften
US8153081B2 (en) 2003-05-29 2012-04-10 Bayer Healthcare Llc Test sensor and method for manufacturing the same
EP2238892A3 (de) 2003-05-30 2011-02-09 Pelikan Technologies Inc. Vorrichtung zur Entnahme von Körperflüssigkeit
US7850621B2 (en) 2003-06-06 2010-12-14 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US20040248306A1 (en) * 2003-06-09 2004-12-09 Hernandez Juan J. Microfluidic water analytical device
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US9200245B2 (en) 2003-06-26 2015-12-01 Seng Enterprises Ltd. Multiwell plate
US20040265172A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method and apparatus for entry and storage of specimens into a microfluidic device
US20040265171A1 (en) * 2003-06-27 2004-12-30 Pugia Michael J. Method for uniform application of fluid into a reactive reagent area
US20080257754A1 (en) * 2003-06-27 2008-10-23 Pugia Michael J Method and apparatus for entry of specimens into a microfluidic device
US20050037508A1 (en) * 2003-08-12 2005-02-17 Juan Hernandez Microfluidic titration apparatus
US7347617B2 (en) * 2003-08-19 2008-03-25 Siemens Healthcare Diagnostics Inc. Mixing in microfluidic devices
US7682833B2 (en) 2003-09-10 2010-03-23 Abbott Point Of Care Inc. Immunoassay device with improved sample closure
WO2005033659A2 (en) 2003-09-29 2005-04-14 Pelikan Technologies, Inc. Method and apparatus for an improved sample capture device
WO2005037095A1 (en) 2003-10-14 2005-04-28 Pelikan Technologies, Inc. Method and apparatus for a variable user interface
US7939030B2 (en) 2003-10-29 2011-05-10 Mec Dynamics Corp. Micro mechanical methods and systems for performing assays
CA2542897A1 (en) 2003-10-30 2005-05-12 Bayer Healthcare Llc Optical cuvette with platform-and-well construction
RU2006118710A (ru) * 2003-10-30 2007-12-10 Байер Хелткэр Ллс (Us) Форматы для оптического анализа и способы их производства
US7655445B2 (en) * 2003-11-12 2010-02-02 Massachusetts Institute Of Technology Methods for synthesis of sulfated saccharides
US7056286B2 (en) 2003-11-12 2006-06-06 Adrian Ravenscroft Medical device anchor and delivery system
DE10354806A1 (de) * 2003-11-21 2005-06-02 Boehringer Ingelheim Microparts Gmbh Probenträger
US7399609B2 (en) * 2003-12-30 2008-07-15 3M Innovative Properties Company Staphylococcus detection
KR20070001935A (ko) * 2003-12-30 2007-01-04 쓰리엠 이노베이티브 프로퍼티즈 컴파니 세포의 세포벽 성분의 시그날 검출을 증진시키는 방법
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US8668656B2 (en) 2003-12-31 2014-03-11 Sanofi-Aventis Deutschland Gmbh Method and apparatus for improving fluidic flow and sample capture
US7150995B2 (en) 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
GB2411002B (en) * 2004-02-11 2006-12-20 Facility Monitoring Systems Lt Particle counter for liquids
US7582264B2 (en) * 2004-02-17 2009-09-01 Ibidi Gmbh Device for microfluid analyses
CA2460898A1 (en) * 2004-03-09 2005-09-09 James Samsoondar Apparatus and method for combining in vivo and in vitro testing
GB0407267D0 (en) * 2004-03-31 2004-05-05 Univ Liverpool Non-orthogonal monitoring of complex systems
US7887750B2 (en) * 2004-05-05 2011-02-15 Bayer Healthcare Llc Analytical systems, devices, and cartridges therefor
US9023641B2 (en) * 2004-05-13 2015-05-05 Advanced Animal Diagnostics Microfluidic device and leucocyte antigen mediated microfluidic assay
EP1751546A2 (de) 2004-05-20 2007-02-14 Albatros Technologies GmbH & Co. KG Bedruckbares wassergel für biosensoren
WO2005120365A1 (en) 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1604733A1 (de) * 2004-06-11 2005-12-14 Corning Incorporated Mikrostrukturentwurf zur Optimisierung der Mischung und des Druckabfalls
US20060000709A1 (en) * 2004-06-30 2006-01-05 Sebastian Bohm Methods for modulation of flow in a flow pathway
US20060002817A1 (en) * 2004-06-30 2006-01-05 Sebastian Bohm Flow modulation devices
US20060000710A1 (en) * 2004-06-30 2006-01-05 Klaus Peter Weidenhaupt Fluid handling methods
US20060001551A1 (en) * 2004-06-30 2006-01-05 Ulrich Kraft Analyte monitoring system with wireless alarm
US8450297B2 (en) * 2004-08-16 2013-05-28 Massachusetts Institute Of Technology Rapid two-step synthesis of anti-coagulants
JP2006076246A (ja) * 2004-09-13 2006-03-23 Rohm Co Ltd 基板の貼り合わせ方法、その貼り合わせ方法を用いたチップ形成方法及びチップ
WO2006036592A1 (en) * 2004-09-23 2006-04-06 University Of Washington Microscale diffusion immunoassay utilizing multivalent reactants
GB0423885D0 (en) * 2004-10-28 2004-12-01 Platform Diagnostics Ltd Blood analysis
WO2006047831A1 (en) * 2004-11-03 2006-05-11 Agen Biomedical Limited Detection device and method
WO2006061026A2 (en) * 2004-12-09 2006-06-15 Inverness Medical Switzerland Gmbh A micro fluidic device and methods for producing a micro fluidic device
US7682817B2 (en) 2004-12-23 2010-03-23 Kimberly-Clark Worldwide, Inc. Microfluidic assay devices
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
EP1843849A2 (de) * 2005-01-12 2007-10-17 Inverness Medical Switzerland GmbH Verfahren zur herstellung einer mikrofluidischen vorrichtung und mikrofluidische vorrichtungen
ES2361169T3 (es) * 2005-01-27 2011-06-14 Boehringer Ingelheim Microparts Gmbh Uso de un dispositivo para el análisis de muestras de líquido.
US20060194325A1 (en) * 2005-02-14 2006-08-31 Gable Jennifer H Fluid handling cassette with a fluid control interface
US20060200070A1 (en) 2005-02-14 2006-09-07 Callicoat David N Method and apparatus for calibrating an analyte detection system with a calibration sample
US20060233667A1 (en) * 2005-04-19 2006-10-19 Chromedx Inc. Joint-diagnostic spectroscopic and biosensor apparatus
US20060228258A1 (en) * 2005-04-12 2006-10-12 Chromedx Inc. Blood collection and measurement apparatus
CA2517299A1 (en) * 2005-08-26 2007-02-26 Chromedx Inc. Hollow needle assembly
US8206650B2 (en) * 2005-04-12 2012-06-26 Chromedx Inc. Joint-diagnostic spectroscopic and biosensor meter
US20100245803A1 (en) * 2005-04-12 2010-09-30 Chromedx Inc. Blood sample holder for spectroscopic analysis
US7740804B2 (en) * 2005-04-12 2010-06-22 Chromedx Inc. Spectroscopic sample holder
CA2507323A1 (en) * 2005-05-13 2006-11-13 Chromedx Inc. Diagnostic whole blood and plasma apparatus
WO2007053186A2 (en) 2005-05-31 2007-05-10 Labnow, Inc. Methods and compositions related to determination and use of white blood cell counts
WO2006132666A1 (en) * 2005-06-06 2006-12-14 Decision Biomarkers, Inc. Assays based on liquid flow over arrays
WO2006137334A1 (ja) * 2005-06-23 2006-12-28 Arkray, Inc. 分析用具
JP4653574B2 (ja) * 2005-06-24 2011-03-16 積水化学工業株式会社 ヘモグロビンＡ１ｃの測定方法
WO2007002480A2 (en) * 2005-06-24 2007-01-04 Board Of Regents, The University Of Texas System Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
EP1904232A2 (de) * 2005-07-07 2008-04-02 Inverness Medical Switzerland GmbH Verfahren zur durchführung eines tests, stützgerät und solch ein stützgerät umfassendes mikroflüssigkeitssystem
EP2261719A3 (de) * 2005-08-01 2011-03-30 ibidi GmbH Probenkammer und Verfahren zu ihrer Herstellung
US9561001B2 (en) 2005-10-06 2017-02-07 Optiscan Biomedical Corporation Fluid handling cassette system for body fluid analyzer
CN1948966B (zh) * 2005-10-13 2010-09-01 财团法人工业技术研究院 微流道生物芯片
CN101292161B (zh) * 2005-10-18 2012-11-28 藤森工业株式会社 监测血栓形成的装置和监测血栓形成的方法
US7723120B2 (en) * 2005-10-26 2010-05-25 General Electric Company Optical sensor array system and method for parallel processing of chemical and biochemical information
US8133741B2 (en) 2005-10-26 2012-03-13 General Electric Company Methods and systems for delivery of fluidic samples to sensor arrays
WO2007075919A2 (en) * 2005-12-22 2007-07-05 Honeywell International Inc. Portable sample analyzer system
GB2433592A (en) 2005-12-23 2007-06-27 Pentapharm Ag Assay for thrombin inhibitors
JP4713397B2 (ja) * 2006-01-18 2011-06-29 株式会社リコー 微小流路構造体及び微小液滴生成システム
ATE432125T1 (de) * 2006-02-09 2009-06-15 Hoffmann La Roche Auf 2d-substraten basierende 3d-strukturen
US7837941B2 (en) * 2006-04-07 2010-11-23 Agamatrix, Inc. Method and apparatus for monitoring alteration of flow characteristics in a liquid sample
JP4915690B2 (ja) * 2006-05-23 2012-04-11 国立大学法人電気通信大学 マイクロ化学チップ装置
US10753927B2 (en) 2006-09-22 2020-08-25 ALERE TECHNOLOGIES GmbH Methods for detecting an analyte
WO2008040015A2 (en) * 2006-09-28 2008-04-03 University Of Washington 3d micro-scale engineered tissue model systems
US8403557B2 (en) * 2006-09-28 2013-03-26 University Of Washington Micromixer using integrated three-dimensional porous structure
US8247464B2 (en) 2006-09-28 2012-08-21 University Of Washington Method of selective foaming for porous polymeric material
EP2078199B1 (de) * 2006-10-12 2013-03-06 Koninklijke Philips Electronics N.V. Nachweissystem und verfahren mit hilfe eines magnetischen und/oder elektrischen etiketts
JP2008128907A (ja) * 2006-11-22 2008-06-05 Fujifilm Corp マイクロ流路チップ
JP4852399B2 (ja) * 2006-11-22 2012-01-11 富士フイルム株式会社 二液合流装置
US7861581B2 (en) * 2006-12-01 2011-01-04 Gamida For Life B.V. Fluidic volume dispense verification tool
JP5105403B2 (ja) * 2006-12-06 2012-12-26 日本サーモスタット株式会社 感温インジケータ
WO2008083687A1 (en) * 2007-01-10 2008-07-17 Scandinavian Micro Biodevices Aps A microfluidic device and a microfluidic system and a method of performing a test
JP2008185564A (ja) * 2007-01-31 2008-08-14 Fujimori Kogyo Co Ltd 血液凝固能の検査方法および血液凝固能の検査装置
WO2008116115A1 (en) * 2007-03-20 2008-09-25 Gary Bodily Apparatus, system, and method for detecting chemicals
US7883898B2 (en) * 2007-05-07 2011-02-08 General Electric Company Method and apparatus for measuring pH of low alkalinity solutions
US8597190B2 (en) 2007-05-18 2013-12-03 Optiscan Biomedical Corporation Monitoring systems and methods with fast initialization
CA2689170A1 (en) * 2007-06-20 2008-12-24 Mec Dynamics Corporation Methods and apparatus for measuring blood coagulation
AU2008269201B2 (en) 2007-06-21 2011-08-18 Gen-Probe Incorporated Instrument and receptacles for use in performing processes
US20090078657A1 (en) * 2007-09-26 2009-03-26 Honeywell International Inc. Device for separation of particulates from a biological sample
EP3181228B1 (de) 2007-10-02 2020-07-29 Labrador Diagnostics LLC Modulare poc-vorrichtungen und ihre verwendung
US20100311616A1 (en) * 2007-10-26 2010-12-09 Tomoyuki Ozawa Reaction chip and method of manufacturing the same
JP5251882B2 (ja) * 2007-10-26 2013-07-31 凸版印刷株式会社 反応チップ及び反応方法、遺伝子処理装置用温度調節機構及び遺伝子処理装置
US9975118B2 (en) * 2007-11-15 2018-05-22 Seng Enterprises Ltd. Device for the study of living cells
US9145540B1 (en) 2007-11-15 2015-09-29 Seng Enterprises Ltd. Device for the study of living cells
JP2011504591A (ja) * 2007-11-26 2011-02-10 アトノミックス アクティーゼルスカブ 信号対ノイズ比を増すための手段および方法を備える、統合型分離および検出カートリッジ
KR20100098656A (ko) * 2007-11-26 2010-09-08 후지모리 고교 가부시키가이샤 마이크로칩 및 혈액 관측 장치
US8372343B2 (en) 2007-12-07 2013-02-12 Sheldon Goldstein Multiple coagulation test cartridge and method of using same
US7850917B2 (en) 2008-03-11 2010-12-14 Ortho-Clinical Diagnostics, Inc. Particle agglutination in a tip
US9201059B2 (en) * 2008-03-14 2015-12-01 Scandinavian Micro Biodevices Aps Microfluidic system and a method of performing a test
US8906303B2 (en) * 2008-03-14 2014-12-09 Clondiag Gmbh Assays
FR2929135A1 (fr) * 2008-03-31 2009-10-02 Commissariat Energie Atomique Dispositif d'aliquotage et de dispense d'un liquide
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
CN102016598B (zh) * 2008-04-25 2013-10-30 爱科来株式会社 微细流路及分析用具
CN102084238B (zh) * 2008-05-05 2016-06-01 洛斯阿拉莫斯国家安全有限责任公司 基于高度简化的侧向流动的核酸样品制备和被动流体流动控制
US8063236B2 (en) * 2008-05-08 2011-11-22 University Of Florida Research Foundation, Inc. Method for transferring N-atoms from metal complexes to organic and inorganic substrates
CA2723707C (en) * 2008-05-09 2016-08-23 Akonni Biosystems Microarray system
WO2010005467A2 (en) 2008-07-09 2010-01-14 Micropoint Bioscience Inc Analytical cartridge with fluid flow control
US8318439B2 (en) 2008-10-03 2012-11-27 Micronics, Inc. Microfluidic apparatus and methods for performing blood typing and crossmatching
FR2937050A1 (fr) * 2008-10-10 2010-04-16 Inst Curie Dispositif de culture cellulaire
JP5729530B2 (ja) * 2008-11-14 2015-06-03 横河電機株式会社 カプセルおよび化学処理用カートリッジ
US8448499B2 (en) 2008-12-23 2013-05-28 C A Casyso Ag Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
FR2943789B1 (fr) * 2009-03-26 2013-07-26 Commissariat Energie Atomique Procede et dispositif pour la caracterisation de la dynamique de coagulation ou sedimentation d'un fluide tel que le sang ou le plasma sanguin
US9347931B2 (en) 2009-04-23 2016-05-24 Dublin City University Lateral flow assay device for coagulation monitoring and method thereof
CA2764678C (en) 2009-06-04 2017-12-12 Lockheed Martin Corporation Multiple-sample microfluidic chip for dna analysis
US9216413B2 (en) * 2009-07-07 2015-12-22 Boehringer Ingelheim Microparts Gmbh Plasma separation reservoir
EP2456355B1 (de) 2009-07-20 2016-09-14 Optiscan Biomedical Corporation Einstellbarer steckverbinder und totraumreduzierung dafür
US9554742B2 (en) 2009-07-20 2017-01-31 Optiscan Biomedical Corporation Fluid analysis system
FR2950358B1 (fr) * 2009-09-18 2015-09-11 Biomerieux Sa Dispositif d'amplification d'acides nucleiques simplifie et son procede de mise en oeuvre
EP2496189A4 (de) 2009-11-04 2016-05-11 Nitinol Devices And Components Inc Entwurf für einen stent mit alternierender ringförmiger brücke und verwendungsverfahren dafür
US20120261356A1 (en) * 2009-12-25 2012-10-18 Josho Gakuen Educational Foundation Device having solid-liquid separation function, micro-tas device, and solid-liquid separation method
CN102821859B (zh) * 2009-12-28 2015-01-21 阿茨拉实验室有限公司 诊断元件、以及包括诊断元件的诊断装置
KR20120123066A (ko) * 2009-12-31 2012-11-07 바스프 에스이 훼손 검출기 및 방법
WO2011094279A1 (en) * 2010-01-26 2011-08-04 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Planar labyrinth micromixer systems and methods
KR100961874B1 (ko) * 2010-04-05 2010-06-09 주식회사 나노엔텍 외부동력 없이 유체가 이동하는 유체분석용 칩
EP2555704B1 (de) 2010-04-08 2019-05-29 Hemosonics, Llc Anzeige von blutstillungsparametern
JP5831448B2 (ja) * 2010-04-14 2015-12-09 日東紡績株式会社 試料中の分析対象物質を測定するための検査器具及びそれを用いた分析対象物質の測定方法
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
WO2011156522A1 (en) 2010-06-09 2011-12-15 Optiscan Biomedical Corporation Measuring analytes in a fluid sample drawn from a patient
EP2624791B1 (de) 2010-10-08 2017-06-21 Confluent Medical Technologies, Inc. Stent mit alternierender ringförmiger brücke
CA2814720C (en) 2010-10-15 2016-12-13 Lockheed Martin Corporation Micro fluidic optic design
BR112013018656B1 (pt) 2011-01-21 2021-03-02 Labrador Diagnostics Llc método para detectar a presença ou concentração de um analito numa amostra de fluido contido num recipiente, e, método de medição da concentração de analito numa amostra de fluido
EP2676136B1 (de) 2011-02-15 2020-12-23 Hemosonics, Llc Vorrichtungen, systeme und verfahren zur hämostase-bewertung
WO2013105987A2 (en) 2011-02-15 2013-07-18 Hemosonics, Llc Characterization of blood hemostasis and oxygen transport parameters
JP5901121B2 (ja) * 2011-02-16 2016-04-06 キヤノン株式会社 流路デバイス、及び該流路デバイスを用いた液体の搬送方法
US20120294767A1 (en) 2011-05-19 2012-11-22 Hemosonics Llc Portable hemostasis analyzer
GB201109203D0 (en) 2011-06-01 2011-07-13 Carclo Technical Plastics Ltd Fluid flow control
EP2729784A4 (de) 2011-07-06 2015-05-13 Optiscan Biomedical Corp Messzelle für flüssigkeitsanalysesystem
JP5592324B2 (ja) * 2011-09-05 2014-09-17 日本電信電話株式会社 凝固活性測定装置および測定方法
US9619627B2 (en) 2011-09-25 2017-04-11 Theranos, Inc. Systems and methods for collecting and transmitting assay results
US8475739B2 (en) 2011-09-25 2013-07-02 Theranos, Inc. Systems and methods for fluid handling
US9632102B2 (en) 2011-09-25 2017-04-25 Theranos, Inc. Systems and methods for multi-purpose analysis
US9664702B2 (en) 2011-09-25 2017-05-30 Theranos, Inc. Fluid handling apparatus and configurations
US20140170735A1 (en) 2011-09-25 2014-06-19 Elizabeth A. Holmes Systems and methods for multi-analysis
US9268915B2 (en) 2011-09-25 2016-02-23 Theranos, Inc. Systems and methods for diagnosis or treatment
US9810704B2 (en) 2013-02-18 2017-11-07 Theranos, Inc. Systems and methods for multi-analysis
US10012664B2 (en) 2011-09-25 2018-07-03 Theranos Ip Company, Llc Systems and methods for fluid and component handling
US9250229B2 (en) 2011-09-25 2016-02-02 Theranos, Inc. Systems and methods for multi-analysis
US20200110081A1 (en) * 2011-09-26 2020-04-09 Carnegie Mellon University Devices and Methods for Detection and Quantification of Immunological Proteins, Pathogenic and Microbial Agents and Cells
SG11201402709WA (en) * 2011-12-06 2014-06-27 Univ Bruxelles Method and device for assaying an antigen present on erythrocytes or an antibody binding to an antigen present on erythrocytes
US9322054B2 (en) 2012-02-22 2016-04-26 Lockheed Martin Corporation Microfluidic cartridge
US9517474B2 (en) 2012-05-18 2016-12-13 University Of Georgia Research Foundation, Inc. Devices and methods for separating particles
ITUD20120137A1 (it) * 2012-07-31 2014-02-01 Alifax Holding S P A Apparato e procedimento per la determinazione della velocita' di sedimentazione del sangue e di altri parametri ad essa correlati
AU2013202778A1 (en) * 2013-03-14 2014-10-02 Gen-Probe Incorporated Systems, methods, and apparatuses for performing automated reagent-based assays
WO2014182844A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
CN111378568A (zh) 2013-09-06 2020-07-07 赛拉诺斯知识产权有限责任公司 用于检测感染性疾病的系统和方法
WO2015035256A2 (en) 2013-09-06 2015-03-12 Theranos, Inc. Devices, systems, methods and kits for receiving a swab
WO2015095239A1 (en) 2013-12-18 2015-06-25 Optiscan Biomedical Corporation Systems and methods for detecting leaks
JP6278772B2 (ja) * 2014-03-19 2018-02-14 テルモ株式会社 血糖値測定用チップ
CN103983769B (zh) * 2014-03-25 2015-11-18 中国海洋大学 一种纳米金免疫层析毛细管的制备方法
AU2015266723B2 (en) * 2014-05-30 2020-02-27 Microfluidics International Corporation Interaction chambers with reduced cavitation
JP6359348B2 (ja) * 2014-06-06 2018-07-18 キヤノンメディカルシステムズ株式会社 センサチップ及びセンサチップへの液体供給方法
US9901922B2 (en) 2014-07-25 2018-02-27 General Electric Company Sample collection and transfer device
US9480981B2 (en) 2014-07-25 2016-11-01 General Electric Company Sample collection and transfer device
US10073091B2 (en) 2014-08-08 2018-09-11 Ortho-Clinical Diagnostics, Inc. Lateral flow assay device
WO2016049552A1 (en) 2014-09-26 2016-03-31 Abbott Point Of Care Inc. Cartridge device identification for coagulation assays in fluid samples
US10114031B2 (en) 2014-09-26 2018-10-30 Abbott Point Of Care Inc. Single channel cartridge device for coagulation assays in fluid samples
CN106999932A (zh) 2014-09-26 2017-08-01 雅培医护站股份有限公司 用于流体样本中的凝结测定的具有流体结的盒设备
CN106999931B (zh) 2014-09-26 2020-08-18 雅培医护站股份有限公司 具有用于测定流体样本中的凝结的微环境传感器的微制造设备
EP3198281B1 (de) 2014-09-26 2023-01-25 Abbott Point Of Care, Inc. Ellagsäureformulierungen zur verwendung bei gerinnungstests
WO2016049527A1 (en) 2014-09-26 2016-03-31 Abbott Point Of Care Inc. Cartridge device with segmented fluidics for assaying coagulation in fluid samples
EP3955003B1 (de) 2014-09-26 2023-06-21 Abbott Point Of Care Inc Sensoren zur prüfung auf koagulation in flüssigen proben
US10288630B2 (en) 2014-09-29 2019-05-14 C A Casyso Gmbh Blood testing system and method
US10539579B2 (en) 2014-09-29 2020-01-21 C A Casyso Gmbh Blood testing system and method
US10175225B2 (en) 2014-09-29 2019-01-08 C A Casyso Ag Blood testing system and method
US9897618B2 (en) 2014-09-29 2018-02-20 C A Casyso Gmbh Blood testing system
US10816559B2 (en) 2014-09-29 2020-10-27 Ca Casyso Ag Blood testing system and method
CN104880562A (zh) * 2015-04-08 2015-09-02 上海盛复源生物医药有限公司 一种l-fabp快速检测试剂及其制备方法
CN104880563A (zh) * 2015-04-08 2015-09-02 上海盛复源生物医药有限公司 一种ngal快速检测试剂及其制备方法
EP3281009A4 (de) * 2015-04-09 2018-11-14 Axela Inc. Wegwerfbare bioassay-kartusche und verfahren zur durchführung mehrerer assay-schritte und fluidtransfer innerhalb der kartusche
USD777343S1 (en) 2015-05-28 2017-01-24 C A Casyso Ag Body fluid cartridge device
US10295554B2 (en) 2015-06-29 2019-05-21 C A Casyso Gmbh Blood testing system and method
US10676719B2 (en) 2015-07-31 2020-06-09 University Of Georgia Research Foundation, Inc. Devices and methods for separating particles
US9658223B2 (en) * 2015-08-13 2017-05-23 Olivia A Hallisey Temperature-independent, portable, and rapid field detection of antigens
JPWO2017056748A1 (ja) * 2015-09-28 2018-07-19 Ｐｈｃホールディングス株式会社 アナライトを分析するセンサ及びアナライトの分析方法
WO2017163341A1 (ja) * 2016-03-23 2017-09-28 デンカ生研株式会社 イムノクロマト法検査デバイスの試料添加部の形成方法及びイムノクロマト法検査デバイス
CN105973787B (zh) * 2016-06-29 2018-12-11 珠海科域生物工程股份有限公司 一种集成有试剂的流动计数池
US10473674B2 (en) 2016-08-31 2019-11-12 C A Casyso Gmbh Controlled blood delivery to mixing chamber of a blood testing cartridge
KR102013184B1 (ko) * 2016-11-01 2019-08-22 주식회사 엘지화학 디엔계 고무 라텍스의 제조방법, 이를 포함하는 abs계 그라프트 공중합체의 제조방법 및 abs계 사출성형품의 제조방법
CN110461473B (zh) * 2016-11-16 2021-11-05 奎多公司 全血分离的装置
US10258741B2 (en) 2016-12-28 2019-04-16 Cequr Sa Microfluidic flow restrictor and system
US10843185B2 (en) 2017-07-12 2020-11-24 Ca Casyso Gmbh Autoplatelet cartridge device
US11779920B2 (en) 2017-08-04 2023-10-10 Sbt Instruments A/S Microfluidic particle analysis device
US20200197923A1 (en) * 2017-09-14 2020-06-25 Siemens Healthcare Diagnostics Inc. Improved liquid test sample dispensing device for the collection of liquid waste and methods of use related thereto
CN108444801A (zh) * 2018-05-11 2018-08-24 石家庄禾柏生物技术股份有限公司 一种具有变径排泡结构的反应囊
CN108931464B (zh) * 2018-07-24 2020-09-11 苏州水木康桥环境工程技术有限公司 一种高精度自动pm2.5成分分析装置及其工作方法
US10429377B1 (en) 2019-03-15 2019-10-01 Coagulation Sciences Llc Coagulation test device, system, and method of use
US11331674B2 (en) 2019-04-29 2022-05-17 Hach Company Liquid mixing
JP7368161B2 (ja) 2019-09-30 2023-10-24 シスメックス株式会社 送液監視方法および検体測定装置
FR3131632A1 (fr) * 2021-12-31 2023-07-07 Biomerieux Carte d’analyse d'un échantillon biologique, procédé de fabrication et de contrôle qualité
GB2616840A (en) * 2022-03-18 2023-09-27 Entia Ltd A cuvette for analysing biological samples
CN114778408B (zh) * 2022-04-12 2023-05-02 深圳市利和兴股份有限公司 一种自动化进出的防水测试平台

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE746089C (de) * 1942-03-11 1944-06-10 Holger J Hesse Dr Ing Verfahren und Vorrichtung zur Bestimmung der Koagulationszeit von Fluessigkeiten, insbesondere von Blut
US2610541A (en) * 1948-01-05 1952-09-16 Jr Ernest Lee Rowland Blood testing apparatus
US3233975A (en) * 1962-03-05 1966-02-08 Ames Lab Tek Inc Prothrombin reaction chamber
US3432268A (en) * 1964-08-28 1969-03-11 Peter Unger Method and apparatus for testing cell suspensions
DE1617732C2 (de) * 1966-03-01 1972-12-21 Promoveo-Sobioda & Cie, Seyssinet (Frankreich) Vorrichtung zur Untersuchung lebender Zellen von Mikroorganismen
BE792465A (fr) * 1971-12-09 1973-03-30 Atomic Energy Commission Rotor perfectionne pour analyseur photometrique rotatif convenant en particulier dans des conditions d'apesanteur
US3799742A (en) * 1971-12-20 1974-03-26 C Coleman Miniaturized integrated analytical test container
US3898982A (en) * 1972-11-13 1975-08-12 Jintan Terumo Co Capillary tube for blood examination
US3856470A (en) * 1973-01-10 1974-12-24 Baxter Laboratories Inc Rotor apparatus
NL7304229A (de) * 1973-03-27 1974-10-01
US3873217A (en) * 1973-07-24 1975-03-25 Atomic Energy Commission Simplified rotor for fast analyzer of rotary cuvette type
US3899296A (en) * 1974-07-17 1975-08-12 Us Energy Whole blood analysis rotor for a multistation dynamic photometer
US3901658A (en) * 1974-07-30 1975-08-26 Us Energy Whole blood analysis rotor assembly having removable cellular sedimentation bowl
SE399768B (sv) * 1975-09-29 1978-02-27 Lilja Jan E Kyvett for provtagning, blandning av, provet med ett reagensmedel och direkt utforande av, serskilt optisk, analys av det med reagensmedlet blandade provet
GB1529195A (en) * 1975-10-28 1978-10-18 Geomet Coagulation rate method and apparatus
FR2349122A1 (fr) * 1976-04-23 1977-11-18 Materiel Telephonique Systeme permettant d'alterer la qualite d'images optiques et de simuler des phenomenes atmospheriques reduisant la visibilite
IT1097442B (it) * 1977-08-18 1985-08-31 Guigan Jean Dispositivo di condizionamento di un campione di liquido in preparazione della sua analisi
FR2409514A1 (fr) * 1977-11-17 1979-06-15 Bretaudiere Jean Pierre Perfectionnement aux appareils d'analyse par centrifugation
US4233029A (en) * 1978-10-25 1980-11-11 Eastman Kodak Company Liquid transport device and method
US4284602A (en) * 1979-12-10 1981-08-18 Immutron, Inc. Integrated fluid manipulator
JPS5711414A (en) * 1980-06-25 1982-01-21 Fujikura Ltd Refractory insulated wire
US4426451A (en) * 1981-01-28 1984-01-17 Eastman Kodak Company Multi-zoned reaction vessel having pressure-actuatable control means between zones
DE3134611A1 (de) * 1981-09-01 1983-03-10 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur durchfuehrung analytischer bestimmungen und hierfuer geeignetes mittel
DE3218037C2 (de) * 1982-05-13 1985-07-18 Kiesewetter, Holger, Dr., 5100 Aachen Vorrichtung zur Bestimmung von Fließeigenschaften, insbesondere der Fließschubspannung, von Suspensionen, insbesondere Blut
DD217896A1 (de) * 1983-07-13 1985-01-23 Univ Schiller Jena Anordnung zur messung der agglutinabilitaet von zellsuspensionen
DE3425008A1 (de) * 1984-07-06 1986-02-06 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und vorrichtung zur durchfuehrung analytischer bestimmungen

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10148210A1 (de) * 2001-09-28 2003-04-24 Ibidi Gmbh Flusskammer
DE10148210B4 (de) * 2001-09-28 2005-09-15 Ibidi Gmbh Flusskammer
US7517499B2 (en) 2001-09-28 2009-04-14 Ibidi Gmbh Flow chamber

Also Published As

Publication number Publication date
AU593001B2 (en) 1990-02-01
EP0212314B1 (de) 1994-04-27
JPH0769330B2 (ja) 1995-07-26
EP0485368B1 (de) 1996-09-25
DE3689812D1 (de) 1994-06-01
EP0212314A2 (de) 1987-03-04
DE3650574D1 (de) 1996-10-31
CA1275231C (en) 1990-10-16
JPH07104356B2 (ja) 1995-11-13
US4756884A (en) 1988-07-12
JPH07117546B2 (ja) 1995-12-18
JPH0694722A (ja) 1994-04-08
EP0483117A3 (en) 1992-09-23
DE3650530D1 (de) 1996-07-18
EP0485368A3 (en) 1992-08-26
DE3650574T2 (de) 1997-03-13
EP0485368A2 (de) 1992-05-13
EP0212314A3 (en) 1989-07-19
AU6088486A (en) 1987-02-12
DE3650610D1 (de) 1997-05-15
DE3689812T2 (de) 1994-09-01
JPH0694724A (ja) 1994-04-08
JP2595422B2 (ja) 1997-04-02
JPH0792169A (ja) 1995-04-07
JPS62129759A (ja) 1987-06-12
JPH0658373B2 (ja) 1994-08-03
EP0488994A2 (de) 1992-06-03
EP0488994B1 (de) 1996-06-12
JPH0694723A (ja) 1994-04-08
EP0483117A2 (de) 1992-04-29
EP0488994A3 (en) 1992-07-01
DE3650530T2 (de) 1996-11-21
EP0483117B1 (de) 1997-04-09

Similar Documents

Publication Publication Date Title
DE3650610T2 (de) Kapillardurchflussgerät
ATA240586A (de) Drehstossmindernde einrichtung
DK95486D0 (da) Stroemningsforbindelseskonstruktion
KR860007755A (ko) 반도체 장치
KR870001757A (ko) 납땜 장치
DE3580479D1 (de) Auftragsvorrichtung.
KR910021406U (ko) 납땜장치
BR8600870A (pt) Dispositivo espalhador
DE3668236D1 (de) Ultraschall-durchflussmesseinrichtung.
DD281916A7 (de) Ordnungseinrichtung
IT1199696B (it) Dispositivo traversafilo
DE3672164D1 (de) Stroemungsabbildungsvorrichtung.
ES287053Y (es) Aparato magnetoterapico
ATE105084T1 (de) Kapillardurchflussgeraet.
KR860013687U (ko) 유량검출장치
KR860006005A (ko) 유량제어장치
FR2588376B1 (fr) Mesureur debitmetrique perfectionne
KR860001920U (ko) 유량 검출 장치
DK592485D0 (da) Flowmaaler
ES284997Y (es) Dispositivo busca-objetos
BR8505298A (pt) Aparelho pro-saude
RO91584A2 (ro) Rotametru
BR6501486U (pt) Dispositivo retentor
KR860009329U (ko) 콤팩트의 체착장치
SE8603927D0 (sv) Fluidanordning

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ROCHE DIAGNOSTICS CORP., INDIANAPOLIS, IND., US