DE3479585D1 - Lactide/caprolactone polymer, method of making the same, composites thereof, and prostheses produced therefrom - Google Patents

Lactide/caprolactone polymer, method of making the same, composites thereof, and prostheses produced therefrom

Info

Publication number
DE3479585D1
DE3479585D1 DE19843479585 DE3479585A DE3479585D1 DE 3479585 D1 DE3479585 D1 DE 3479585D1 DE 19843479585 DE19843479585 DE 19843479585 DE 3479585 A DE3479585 A DE 3479585A DE 3479585 D1 DE3479585 D1 DE 3479585D1
Authority
DE
Grant status
Grant
Patent type
Prior art keywords
lactide
composites
making
same
method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE19843479585
Inventor
Steve Lin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OSTEONICS-BIOMATERIALS DIVISION
OSTEONICS BIOMATERIALS DIVISIO
Original Assignee
OSTEONICS-BIOMATERIALS DIVISION
OSTEONICS BIOMATERIALS DIVISIO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Grant date

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08Lactones or lactides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, E.G. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/08Muscles; Tendons; Ligaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/443Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with carbon fillers
DE19843479585 1983-05-05 1984-04-16 Lactide/caprolactone polymer, method of making the same, composites thereof, and prostheses produced therefrom Expired DE3479585D1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US06491927 US4643734A (en) 1983-05-05 1983-05-05 Lactide/caprolactone polymer, method of making the same, composites thereof, and prostheses produced therefrom
PCT/US1984/000568 WO1984004311A1 (en) 1983-05-05 1984-04-16 Lactide/caprolactone polymer, method of making the same, composites thereof, and prostheses produced therefrom

Publications (1)

Publication Number Publication Date
DE3479585D1 true DE3479585D1 (en) 1989-10-05

Family

ID=23954244

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19843479585 Expired DE3479585D1 (en) 1983-05-05 1984-04-16 Lactide/caprolactone polymer, method of making the same, composites thereof, and prostheses produced therefrom

Country Status (6)

Country Link
US (1) US4643734A (en)
EP (1) EP0148852B1 (en)
JP (1) JPH0762066B2 (en)
CA (1) CA1234247A (en)
DE (1) DE3479585D1 (en)
WO (1) WO1984004311A1 (en)

Families Citing this family (109)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713075A (en) * 1981-06-10 1987-12-15 Kurland Kenneth Z Method for the repair of connective tissue
US4595713A (en) * 1985-01-22 1986-06-17 Hexcel Corporation Medical putty for tissue augmentation
EP0226061B1 (en) * 1985-12-17 1994-02-16 United States Surgical Corporation High molecular weight bioresorbable polymers and implantation devices thereof
US5061281A (en) * 1985-12-17 1991-10-29 Allied-Signal Inc. Bioresorbable polymers and implantation devices thereof
US4759765A (en) * 1986-03-17 1988-07-26 Minnesota Mining And Manufacturing Company Tissue augmentation device
FI81498C (en) * 1987-01-13 1990-11-12 Biocon Oy Kirurgiska goods and the instrument.
DE3708916C2 (en) * 1987-03-19 1989-10-12 Boehringer Ingelheim Kg, 6507 Ingelheim, De
US4772287A (en) * 1987-08-20 1988-09-20 Cedar Surgical, Inc. Prosthetic disc and method of implanting
US5092884A (en) * 1988-03-24 1992-03-03 American Cyanamid Company Surgical composite structure having absorbable and nonabsorbable components
US5502158A (en) * 1988-08-08 1996-03-26 Ecopol, Llc Degradable polymer composition
US6323307B1 (en) 1988-08-08 2001-11-27 Cargill Dow Polymers, Llc Degradation control of environmentally degradable disposable materials
US5444113A (en) * 1988-08-08 1995-08-22 Ecopol, Llc End use applications of biodegradable polymers
US5634946A (en) * 1988-08-24 1997-06-03 Focal, Inc. Polymeric endoluminal paving process
DE68922497D1 (en) 1988-08-24 1995-06-08 Marvin J Slepian Endoluminal seal with bisdegradierbaren polymeric.
US5133739A (en) * 1990-02-06 1992-07-28 Ethicon, Inc. Segmented copolymers of ε-caprolactone and glycolide
US5342395A (en) * 1990-07-06 1994-08-30 American Cyanamid Co. Absorbable surgical repair devices
NL9001984A (en) * 1990-09-10 1992-04-01 Stamicarbon A method for producing an article from a copolymer of lactide and epsilon-caprolactone for medical applications.
JPH06506366A (en) * 1990-12-06 1994-07-21
US5320624A (en) * 1991-02-12 1994-06-14 United States Surgical Corporation Blends of glycolide and/or lactide polymers and caprolactone and/or trimethylene carbonate polymers and absorbable surgical devices made therefrom
US6228954B1 (en) 1991-02-12 2001-05-08 United States Surgical Corporation Blends of glycolide and/or lactide polymers and caprolactone and/or trimethylene carbonate polymers and absorabable surgical devices made therefrom
CA2060635A1 (en) * 1991-02-12 1992-08-13 Keith D'alessio Bioabsorbable medical implants
US5136017A (en) * 1991-02-22 1992-08-04 Polysar Financial Services S.A. Continuous lactide polymerization
US5132397A (en) * 1991-04-02 1992-07-21 Polysar Financial Services S.A. 4-valerolactone copolymers
DE4229924C2 (en) * 1991-04-17 1995-12-07 Juergens Christian Dr Med Use of resorbable lactide copolymers
US5576418A (en) * 1992-06-29 1996-11-19 Jurgens; Christian Resorbable biocompatible copolymers and their use
DE4112489C2 (en) * 1991-04-17 1994-06-09 Christian Dr Med Juergens Use of absorbable, biocompatible copolymers for topical treatment of human or animal skin
US5247058A (en) * 1992-01-24 1993-09-21 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5142023A (en) * 1992-01-24 1992-08-25 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5247059A (en) * 1992-01-24 1993-09-21 Cargill, Incorporated Continuous process for the manufacture of a purified lactide from esters of lactic acid
US5258488A (en) * 1992-01-24 1993-11-02 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US6326458B1 (en) 1992-01-24 2001-12-04 Cargill, Inc. Continuous process for the manufacture of lactide and lactide polymers
US6005067A (en) 1992-01-24 1999-12-21 Cargill Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5338822A (en) * 1992-10-02 1994-08-16 Cargill, Incorporated Melt-stable lactide polymer composition and process for manufacture thereof
JP3258326B2 (en) * 1992-10-02 2002-02-18 カーギル, インコーポレイテッド Paper and a manufacturing method thereof coated with a melt-stable lactide polymer
EP0615555B1 (en) * 1992-10-02 2001-03-21 Cargill, Incorporated A melt-stable lactide polymer fabric and process for manufacture thereof
US5925065A (en) * 1993-06-11 1999-07-20 United States Surgical Corporation Coated gut suture
CA2123647C (en) * 1993-06-11 2007-04-17 Steven L. Bennett Bioabsorbable copolymer and coating composition containing same
US5578662A (en) 1994-07-22 1996-11-26 United States Surgical Corporation Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
US6339130B1 (en) * 1994-07-22 2002-01-15 United States Surgical Corporation Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
US6335383B1 (en) * 1994-10-18 2002-01-01 Ethicon, Inc. Microdispersions for coating surgical devices
US5607686A (en) * 1994-11-22 1997-03-04 United States Surgical Corporation Polymeric composition
US6106556A (en) * 1994-12-02 2000-08-22 Omeros Medical Systems, Inc. Tendon and ligament repair system
JP3682299B2 (en) * 1994-12-02 2005-08-10 オメロス コーポレーション Fastener for repairing severed tendon or ligament
US6361789B1 (en) * 1995-10-27 2002-03-26 Sanitaria Scaligera Spa Bioresorbable material and method for producing the same
DE69728307D1 (en) * 1996-01-19 2004-05-06 United States Surgical Corp Absorbable polymer blends and surgical articles therefrom
US5844067A (en) * 1996-04-18 1998-12-01 Erneta; Modesto Process for producing absorbable segmented copolymers with a substantially uniform sequence distribution
US5786022A (en) * 1996-10-31 1998-07-28 Ethicon, Inc. Coating mixture for surgical articles
EP0937469A3 (en) * 1998-02-24 2000-10-18 SORIN BIOMEDICA CARDIO S.p.A. A coated vascular prosthesis and a method for its production
US5964764A (en) * 1998-03-24 1999-10-12 Hugh S. West, Jr. Apparatus and methods for mounting a ligament graft to a bone
US6177094B1 (en) 1998-04-30 2001-01-23 United States Surgical Corporation Bioabsorbable blends and coating composition containing same
EP0997487A1 (en) * 1998-10-29 2000-05-03 SOLVAY (Société Anonyme) Copolymers of e-caprolactone and cyclic esters of alpha-hydroxyacids and polyurethanes derivable from these polymers
EP1048683B1 (en) * 1998-11-13 2005-05-25 DAICEL CHEMICAL INDUSTRIES, Ltd. Aliphatic copolymer, production process, aliphatic polyester resin composition, various uses, coating composition, and agricultural or horticultural particulate composition comprising degradable coating film
US7220469B2 (en) 1998-11-13 2007-05-22 Daicel Chemical Industries, Ltd. Aliphatic copolyester resin, a preparation method, an aliphatic polyester resin composition, uses thereof, a coating composition, a particle-state composition for agriculture and gardening coated by degradable layer
US6884427B1 (en) * 1999-02-08 2005-04-26 Aderans Research Institute, Inc. Filamentary means for introducing agents into tissue of a living host
JP2001309969A (en) * 2000-04-28 2001-11-06 Gunze Ltd Artificial dura mater
CN1277585C (en) * 2000-08-08 2006-10-04 阿德兰斯研究院有限公司 Scaffolds for tissue engineered hair
US7192604B2 (en) 2000-12-22 2007-03-20 Ethicon, Inc. Implantable biodegradable devices for musculoskeletal repair or regeneration
US20040068284A1 (en) * 2002-01-29 2004-04-08 Barrows Thomas H. Method for stimulating hair growth and kit for carrying out said method
US6645618B2 (en) 2001-06-15 2003-11-11 3M Innovative Properties Company Aliphatic polyester microfibers, microfibrillated articles and use thereof
US6890649B2 (en) 2002-04-26 2005-05-10 3M Innovative Properties Company Aliphatic polyester microfibers, microfibrillated articles and use thereof
GB0116341D0 (en) * 2001-07-04 2001-08-29 Smith & Nephew Biodegradable polymer systems
DE10200738A1 (en) * 2002-01-11 2003-08-07 Boehringer Ingelheim Pharma A process for preparing resorbable polyesters by bulk polymerization
US6706854B2 (en) 2002-01-11 2004-03-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process for preparing reabsorbable polyesters by mass polymerization
US20040210310A1 (en) * 2002-12-10 2004-10-21 Trieu Hai H. Implant system and method for intervertebral disc augmentation
US7012106B2 (en) * 2003-03-28 2006-03-14 Ethicon, Inc. Reinforced implantable medical devices
US8016865B2 (en) 2003-09-29 2011-09-13 Depuy Mitek, Inc. Method of performing anterior cruciate ligament reconstruction using biodegradable interference screw
GB0329654D0 (en) 2003-12-23 2004-01-28 Smith & Nephew Tunable segmented polyacetal
US7597885B2 (en) * 2004-03-26 2009-10-06 Aderans Research Institute, Inc. Tissue engineered biomimetic hair follicle graft
WO2005099628A3 (en) * 2004-04-13 2005-12-08 Cook Inc Implantable frame with variable compliance
US20060276882A1 (en) * 2005-04-11 2006-12-07 Cook Incorporated Medical device including remodelable material attached to frame
CA2564605A1 (en) * 2004-05-12 2005-12-01 Massachusetts Institute Of Technology Manufacturing process, such as three-dimensional printing, including solvent vapor filming and the like
JP2008509679A (en) * 2004-08-13 2008-04-03 アデランス リサーチ インスティテュート インコーポレイテッド Organogenesis from isolated cells
JP4659451B2 (en) * 2004-12-28 2011-03-30 グンゼ株式会社 In vivo small content of the metal catalyst resorbable polymers and their preparation
GB0611660D0 (en) * 2005-06-13 2006-07-19 Veterinary Innovations Ltd Method and apparatus for fixing bone fractures
WO2007062386A3 (en) * 2005-11-22 2007-11-01 Aderans Res Inst Inc Hair follicle graft from tissue engineered skin
US20070122387A1 (en) * 2005-11-22 2007-05-31 Aderans Research Institute, Inc. Hair grafts derived from plucked hair
JP5334360B2 (en) 2006-06-28 2013-11-06 グンゼ株式会社 Preparation of the biodegradable and bioabsorbable polymer containing a small amount of metal catalyst
WO2008001633A1 (en) 2006-06-28 2008-01-03 Gunze Limited Bio-degradable/absorbable polymer having reduced metal catalyst content, and process for production thereof
US7385020B2 (en) 2006-10-13 2008-06-10 3M Innovative Properties Company 2-octyl (meth)acrylate adhesive composition
US9555167B2 (en) 2006-12-11 2017-01-31 3M Innovative Properties Company Biocompatible antimicrobial compositions
WO2008129245A1 (en) 2007-04-18 2008-10-30 Smith & Nephew Plc Expansion moulding of shape memory polymers
US9770534B2 (en) 2007-04-19 2017-09-26 Smith & Nephew, Inc. Graft fixation
JP5520814B2 (en) 2007-04-19 2014-06-11 スミス アンド ネフュー インコーポレーテッドSmith & Nephew,Inc. Multi-modal shape memory polymer
US7985537B2 (en) * 2007-06-12 2011-07-26 Aderans Research Institute, Inc. Methods for determining the hair follicle inductive properties of a composition
US20110038911A1 (en) * 2007-08-09 2011-02-17 Gunze Limited Prosthetic material for living organ
JP2009131358A (en) * 2007-11-29 2009-06-18 Gunze Ltd Artificial dura mater
WO2009069558A1 (en) * 2007-11-29 2009-06-04 Gunze Limited Lactide/ε-caprolactone copolymer for medical implant, method for producing lactide/ε-caprolactone copolymer for medical implant, medical implant and artificial dura mater
JP2009132769A (en) * 2007-11-29 2009-06-18 Gunze Ltd LACTIDE/ε-CAPROLACTONE COPOLYMER FOR MEDICAL IMPLANT
EP2235266A1 (en) * 2007-12-21 2010-10-06 3M Innovative Properties Company Retroreflective pavement markings
JP5670887B2 (en) 2008-06-12 2015-02-18 スリーエム イノベイティブ プロパティズ カンパニー Biocompatible hydrophilic composition
JP5485988B2 (en) 2008-06-12 2014-05-07 スリーエム イノベイティブ プロパティズ カンパニー Meltblown microfibers and manufacturing method
CN103896908B (en) 2008-08-29 2016-08-31 伍德伊万特-费休股份有限公司 A mixture of lactide derivative prepared
EP2414574A4 (en) 2009-03-31 2013-03-27 3M Innovative Properties Co Dimensionally stable nonwoven fibrous webs and methods of making and using the same
JP5820370B2 (en) * 2009-05-20 2015-11-24 アーセナル メディカル, インコーポレイテッド Medical implants
US20110319987A1 (en) * 2009-05-20 2011-12-29 Arsenal Medical Medical implant
US9309347B2 (en) 2009-05-20 2016-04-12 Biomedical, Inc. Bioresorbable thermoset polyester/urethane elastomers
US8888840B2 (en) * 2009-05-20 2014-11-18 Boston Scientific Scimed, Inc. Drug eluting medical implant
US8992601B2 (en) 2009-05-20 2015-03-31 480 Biomedical, Inc. Medical implants
CN102753745A (en) 2009-12-17 2012-10-24 3M创新有限公司 Dimensionally stable nonwoven fibrous webs, melt blown fine fibers, and methods of making and using the same
US9194065B2 (en) 2009-12-17 2015-11-24 3M Innovative Properties Company Dimensionally stable nonwoven fibrous webs and methods of making and using the same
US8932704B2 (en) 2010-02-23 2015-01-13 3M Innovative Properties Company Dimensionally stable nonwoven fibrous webs and methods of making and using the same
JP2011206095A (en) * 2010-03-29 2011-10-20 Gunze Ltd Fistula treatment material
EP2590629B1 (en) 2010-07-09 2014-12-03 InnoCore Technologies B.V. Biodegradable phase separated segmented multi block co-polymers and release of biologically active polypeptides
US9611572B2 (en) 2010-10-14 2017-04-04 3M Innovative Properties Company Dimensionally stable nonwoven fibrous webs, and methods of making and using the same
JP5208184B2 (en) * 2010-11-10 2013-06-12 グンゼ株式会社 In vivo small content of the metal catalyst resorbable polymers and their preparation
US20160235057A1 (en) 2013-09-30 2016-08-18 3M Innovative Properties Company Compositions, Wipes, and Methods
WO2015047890A1 (en) 2013-09-30 2015-04-02 3M Innovative Properties Company Fibers and wipes with epoxidized fatty ester disposed thereon, and methods
CN105579630B (en) 2013-09-30 2018-03-23 3M创新有限公司 Fibers, wipes and methods
WO2015060192A1 (en) * 2013-10-23 2015-04-30 株式会社ダイセル Production method for lactone polymer

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3284417A (en) * 1963-11-13 1966-11-08 Union Carbide Corp Process for the preparation of lactone polyesters
US4057537A (en) * 1975-01-28 1977-11-08 Gulf Oil Corporation Copolymers of L-(-)-lactide and epsilon caprolactone
US4045418A (en) * 1975-01-28 1977-08-30 Gulf Oil Corporation Copolymers of D,L-lactide and epsilon caprolactone
US4104281A (en) * 1976-12-08 1978-08-01 Gulf Research & Development Company Process for preparing novel isomeric dicarboxy, di (hydroxymethyl) diphenylmethane dilactones
US4243775A (en) * 1978-11-13 1981-01-06 American Cyanamid Company Synthetic polyester surgical articles
US4329743A (en) * 1979-04-27 1982-05-18 College Of Medicine And Dentistry Of New Jersey Bio-absorbable composite tissue scaffold
US4379138A (en) * 1981-12-28 1983-04-05 Research Triangle Institute Biodegradable polymers of lactones
US4443430A (en) * 1982-11-16 1984-04-17 Ethicon, Inc. Synthetic absorbable hemostatic agent

Also Published As

Publication number Publication date Type
CA1234247A1 (en) grant
EP0148852A1 (en) 1985-07-24 application
CA1234247A (en) 1988-03-15 grant
EP0148852B1 (en) 1989-08-30 grant
US4643734A (en) 1987-02-17 grant
JPH0762066B2 (en) 1995-07-05 grant
JPS60501217A (en) 1985-08-01 application
WO1984004311A1 (en) 1984-11-08 application
EP0148852A4 (en) 1985-10-14 application

Similar Documents

Publication Publication Date Title
JPS6076531A (en) Novel ester, manufacture and use
JPS63203154A (en) Artificial tendon
JPS59163403A (en) Glove and production thereof
JPS59140259A (en) Organopolysiloxane composition, manufacture and use
JPS5964054A (en) Artificial organ and production thereof
JPS63211302A (en) Diaper and continuous production thereof
JPS6341483A (en) Titanocenes, production thereof and composition thereof
GB2189150B (en) Prosthesis and process for its manufacture
JPS63308049A (en) Production of super-stretchable polymer material, super-stretchable material and production of article using the same
JPS56125042A (en) Bone substitute material and production thereof
JPS63260549A (en) Prosthesis material and its production
JPS56161425A (en) Super high molecular polyethylene forming powder and manufacture thereof
JPS60136597A (en) Desulfatohirudine, manufacture and pharmaceutical composition
EP0515208A3 (en) Cellulose powder and method of producing the same
JPS60226893A (en) 11 beta-aryl-estradiene, manufacture and antigestogenic and antiglucocorticoidal medicinal composition
JPS59214443A (en) Artificial implant material
JPS59196309A (en) High molecular weight water-soluble polymer and coagulation therewith
JPS59189143A (en) Manufacture of graft rubber-containing polymer powder
JPS5964058A (en) Pasturized artificial organ and production thereof
JPS58180142A (en) Artificial tooth and production thereof
JPS63242263A (en) Artificial bone material
JPS63288156A (en) Medical bandage product and method for constituting the same
JPS59209117A (en) Manufacture of artificial decorative coating, manufacturing device thereof and product obtained through said method
JPS6333463A (en) Thermoplastic composition and its production
JPS59101149A (en) Sticky bandage and production thereof

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee