DE3366279D1 - Substituted tetrahydropyridazino(1,6-a)benzimidazoles - Google Patents
Substituted tetrahydropyridazino(1,6-a)benzimidazolesInfo
- Publication number
- DE3366279D1 DE3366279D1 DE8383106690T DE3366279T DE3366279D1 DE 3366279 D1 DE3366279 D1 DE 3366279D1 DE 8383106690 T DE8383106690 T DE 8383106690T DE 3366279 T DE3366279 T DE 3366279T DE 3366279 D1 DE3366279 D1 DE 3366279D1
- Authority
- DE
- Germany
- Prior art keywords
- tetrahydropyridazino
- substituted
- benzimidazoles
- benzimidazole
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001556 benzimidazoles Chemical class 0.000 title 1
- JYZIHLWOWKMNNX-UHFFFAOYSA-N benzimidazole Chemical compound C1=C[CH]C2=NC=NC2=C1 JYZIHLWOWKMNNX-UHFFFAOYSA-N 0.000 abstract 2
- ISLRSICOYCFPOO-UHFFFAOYSA-N 1,2,3,4-tetrahydropyridazino[1,6-a]benzimidazole Chemical class C1=CC=C2N3NCCCC3=NC2=C1 ISLRSICOYCFPOO-UHFFFAOYSA-N 0.000 abstract 1
- -1 2-methylamino-6 Chemical class 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 229940124630 bronchodilator Drugs 0.000 abstract 1
- 239000000168 bronchodilator agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/397,300 US4391806A (en) | 1982-07-12 | 1982-07-12 | Substituted tetrahydropyridazino-(1,6-A)benzimidazoles and use as bronchodilators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3366279D1 true DE3366279D1 (de) | 1986-10-23 |
Family
ID=23570652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8383106690T Expired DE3366279D1 (de) | 1982-07-12 | 1983-07-08 | Substituted tetrahydropyridazino(1,6-a)benzimidazoles |
Country Status (6)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4391807A (en) * | 1982-07-12 | 1983-07-05 | The Dow Chemical Company | 6-Substituted tetrahydroimidazo[2,1-a]phthalazines and use as bronchodilators |
| US4485106A (en) * | 1982-07-12 | 1984-11-27 | The Dow Chemical Company | Substituted tetrahydrotetrazolo[5,1-a]phthalazines |
| US5356908A (en) * | 1989-04-21 | 1994-10-18 | E. I. Du Pont De Nemours And Company | Fungicidal oxazolidinones |
| WO1991018812A1 (en) * | 1990-05-30 | 1991-12-12 | Fanuc Ltd | Device for keeping and feeding stacked works |
| MX2017011433A (es) * | 2015-03-18 | 2017-11-10 | Bristol Myers Squibb Co | Compuestos heterociclicos triciclicos utiles como inhibidores del factor de necrosis tumoral (tnf). |
| CA2980161A1 (en) * | 2015-03-18 | 2016-09-22 | Bristol-Myers Squibb Company | Heterocyclic compounds useful as inhibitors of tnf |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3704300A (en) * | 1971-04-09 | 1972-11-28 | Sandoz Ag | Imidazo(2,1-a)phthalazines |
| AT336605B (de) * | 1974-09-19 | 1977-05-10 | Lepetit Spa | Verfahren zur herstellung von neuen triazolopyridazinen und ihren salzen |
| GB1583911A (en) * | 1977-02-09 | 1981-02-04 | Allen & Hanburys Ltd | Imidazopyridazines and their use as therapeutic agents |
| US4233301A (en) * | 1977-05-16 | 1980-11-11 | Merck & Co., Inc. | Novel imidazoazines and imidazodiazines |
| US4166851A (en) * | 1977-05-16 | 1979-09-04 | Merck & Co., Inc. | Certain imidazo(1,2a)pyridine derivatives |
| US4391807A (en) * | 1982-07-12 | 1983-07-05 | The Dow Chemical Company | 6-Substituted tetrahydroimidazo[2,1-a]phthalazines and use as bronchodilators |
-
1982
- 1982-07-12 US US06/397,300 patent/US4391806A/en not_active Expired - Lifetime
-
1983
- 1983-07-07 CA CA000432031A patent/CA1194475A/en not_active Expired
- 1983-07-08 EP EP83106690A patent/EP0100461B1/en not_active Expired
- 1983-07-08 DE DE8383106690T patent/DE3366279D1/de not_active Expired
- 1983-07-08 AT AT83106690T patent/ATE22293T1/de not_active IP Right Cessation
- 1983-07-11 JP JP58124878A patent/JPS5921688A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| EP0100461A3 (en) | 1984-08-22 |
| JPS5921688A (ja) | 1984-02-03 |
| US4391806A (en) | 1983-07-05 |
| JPH0419231B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1992-03-30 |
| ATE22293T1 (de) | 1986-10-15 |
| EP0100461B1 (en) | 1986-09-17 |
| CA1194475A (en) | 1985-10-01 |
| EP0100461A2 (en) | 1984-02-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |