DE3365914D1 - Process for the preparation of finely divided p-butoxyphenyl acethydroxamic acid, and compositions containing them - Google Patents
Process for the preparation of finely divided p-butoxyphenyl acethydroxamic acid, and compositions containing themInfo
- Publication number
- DE3365914D1 DE3365914D1 DE8383201719T DE3365914T DE3365914D1 DE 3365914 D1 DE3365914 D1 DE 3365914D1 DE 8383201719 T DE8383201719 T DE 8383201719T DE 3365914 T DE3365914 T DE 3365914T DE 3365914 D1 DE3365914 D1 DE 3365914D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- butoxyphenyl
- compositions containing
- finely divided
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- MXJWRABVEGLYDG-UHFFFAOYSA-N bufexamac Chemical compound CCCCOC1=CC=C(CC(=O)NO)C=C1 MXJWRABVEGLYDG-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 3
- 239000003637 basic solution Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU84530A LU84530A1 (fr) | 1982-12-13 | 1982-12-13 | Procede de preparation d'acide p-butoxyphenylacethydroxamique a l'etat finement divise et composition contenant cet acide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE3365914D1 true DE3365914D1 (en) | 1986-10-09 |
Family
ID=19730000
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE8383201719T Expired DE3365914D1 (en) | 1982-12-13 | 1983-12-05 | Process for the preparation of finely divided p-butoxyphenyl acethydroxamic acid, and compositions containing them |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4534911A (https=) |
| EP (1) | EP0116182B2 (https=) |
| JP (1) | JPS59110655A (https=) |
| AT (1) | ATE21889T1 (https=) |
| CA (1) | CA1218675A (https=) |
| DE (1) | DE3365914D1 (https=) |
| LU (1) | LU84530A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0130160B1 (en) * | 1983-06-22 | 1988-01-07 | The Ohio State University Research Foundation | Small particle formation |
| DE3604050A1 (de) * | 1986-02-08 | 1987-08-13 | Boehringer Mannheim Gmbh | Thioether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| EP0885609A1 (en) * | 1997-06-17 | 1998-12-23 | Continental Pharma Incorporated | Use of a pharmaceutical composition in the treatment of traumatic arthritis in horses |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB921536A (en) * | 1960-02-18 | 1963-03-20 | Basf Ag | Substituted n-hydroxyureas and a process for their manufacture |
| SU390074A1 (ru) * | 1970-08-04 | 1973-07-11 | Всесоюзный научно исследовательский , проектный институт механической обработки полезных ископаемых | Способ получения алкилгидроксамовых |
| SU632690A1 (ru) * | 1977-06-08 | 1978-11-15 | Предприятие П/Я М-5245 | Способ получени с7-с9-алкилгидроксамовых кислот |
| JPS5777646A (en) * | 1980-10-31 | 1982-05-15 | Kanto Kagaku Kk | Preparation of hydroxamic acid |
-
1982
- 1982-12-13 LU LU84530A patent/LU84530A1/fr unknown
-
1983
- 1983-01-26 JP JP58010017A patent/JPS59110655A/ja active Granted
- 1983-12-05 EP EP83201719A patent/EP0116182B2/fr not_active Expired
- 1983-12-05 AT AT83201719T patent/ATE21889T1/de not_active IP Right Cessation
- 1983-12-05 DE DE8383201719T patent/DE3365914D1/de not_active Expired
- 1983-12-07 US US06/558,885 patent/US4534911A/en not_active Expired - Lifetime
- 1983-12-12 CA CA000443104A patent/CA1218675A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0116182B1 (fr) | 1986-09-03 |
| JPS6121618B2 (https=) | 1986-05-28 |
| CA1218675A (en) | 1987-03-03 |
| US4534911A (en) | 1985-08-13 |
| LU84530A1 (fr) | 1984-10-22 |
| EP0116182B2 (fr) | 1989-12-27 |
| EP0116182A1 (fr) | 1984-08-22 |
| ATE21889T1 (de) | 1986-09-15 |
| JPS59110655A (ja) | 1984-06-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8363 | Opposition against the patent | ||
| 8366 | Restricted maintained after opposition proceedings |