DE2966030D1 - Antisecretory heterocyclic guanidine derivatives, process for their manufacture and pharmaceutical compositions containing them - Google Patents
Antisecretory heterocyclic guanidine derivatives, process for their manufacture and pharmaceutical compositions containing themInfo
- Publication number
- DE2966030D1 DE2966030D1 DE7979302212T DE2966030T DE2966030D1 DE 2966030 D1 DE2966030 D1 DE 2966030D1 DE 7979302212 T DE7979302212 T DE 7979302212T DE 2966030 T DE2966030 T DE 2966030T DE 2966030 D1 DE2966030 D1 DE 2966030D1
- Authority
- DE
- Germany
- Prior art keywords
- antisecretory
- manufacture
- pharmaceutical compositions
- compositions containing
- guanidine derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7840706 | 1978-10-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE2966030D1 true DE2966030D1 (en) | 1983-09-08 |
Family
ID=10500371
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE7979302212T Expired DE2966030D1 (en) | 1978-10-16 | 1979-10-15 | Antisecretory heterocyclic guanidine derivatives, process for their manufacture and pharmaceutical compositions containing them |
Country Status (6)
Country | Link |
---|---|
US (1) | US4374836A (de) |
EP (1) | EP0010894B1 (de) |
JP (1) | JPS5553288A (de) |
AT (1) | ATE4383T1 (de) |
CA (1) | CA1218066A (de) |
DE (1) | DE2966030D1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4578459A (en) * | 1973-05-03 | 1986-03-25 | Smithkline & French Laboratories Limited | Heterocyclic alkylaminoheterocycles |
US4467087A (en) * | 1973-05-03 | 1984-08-21 | Smith Kline & French Laboratories Limited | 1,2,4-Triazines |
US4521418A (en) * | 1979-02-21 | 1985-06-04 | Smith Kline & French Laboratories Limited | Guanidinothiazolyl derivatives |
NL189197C (nl) * | 1979-09-04 | 1993-02-01 | Bristol Myers Squibb Co | 3,4-digesubstitueerde-1,2,5-thiadiazool-1-oxiden en 1,1-dioxiden, bereiding daarvan alsmede farmaceutische preparaten. |
IL61234A (en) * | 1979-10-24 | 1984-03-30 | Smith Kline French Lab | Guanidino thiazolyl alkylamino(alkylthioalkylamino)nitrotetrahydropyridines,process for preparing them and pharmaceutical compositions containing them |
GR71929B (de) * | 1979-11-13 | 1983-08-19 | Ici Ltd | |
US4352933A (en) * | 1981-02-06 | 1982-10-05 | Smithkline Beckman Corporation | Chemical methods and intermediates for preparing substituted pyrimidinones |
EP0065823A1 (de) * | 1981-05-13 | 1982-12-01 | Imperial Chemical Industries Plc | Heterozyklische Guanidinderivate als Histamin-H-2-Antagonisten |
IE53068B1 (en) * | 1981-06-15 | 1988-05-25 | Merck & Co Inc | Diamino isothiazole-1-oxides and -1,1-dioxides as gastic secretion inhibitors |
US5171860A (en) * | 1981-06-15 | 1992-12-15 | Merck & Co., Inc. | Diamino isothiazole-1-oxides and 1,1 dioxides as gastric secretion inhibitors |
GR79384B (de) * | 1982-08-20 | 1984-10-22 | Hoechst Uk Ltd | |
GB8318638D0 (en) * | 1983-07-09 | 1983-08-10 | Smith Kline French Lab | Chemical compounds |
US4552899A (en) * | 1984-04-09 | 1985-11-12 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
GB8421427D0 (en) * | 1984-08-23 | 1984-09-26 | Smith Kline French Lab | Chemical compounds |
US6025355A (en) | 1997-05-19 | 2000-02-15 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
US6242198B1 (en) | 1996-07-25 | 2001-06-05 | Cambridge Neuroscience, Inc. | Methods of treatment of eye trauma and disorders |
US6756389B2 (en) * | 1996-08-09 | 2004-06-29 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1338169A (en) * | 1971-03-09 | 1973-11-21 | Smith Kline French Lab | Ureas thioureas and guanidines |
GB1419994A (en) * | 1973-05-03 | 1976-01-07 | Smith Kline French Lab | Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them |
US4104381A (en) * | 1973-05-03 | 1978-08-01 | Smith Kline & French Laboratories Limited | Pharmacologically active compounds |
US4005205A (en) * | 1974-04-24 | 1977-01-25 | Smith Kline & French Laboratories Limited | Compositions and methods for inhibiting H2 histamine receptors |
US4218452A (en) * | 1975-10-02 | 1980-08-19 | Smith Kline & French Laboratories Limited | Substituted 4-pyrimidone compounds, compositions and methods of use |
IN146736B (de) | 1975-10-02 | 1979-08-25 | Smith Kline French Lab | |
US4154834A (en) * | 1975-12-29 | 1979-05-15 | Smith Kline & French Laboratories Limited | Substituted isocytosines having histamine H2 -antagonist activity |
US4216318A (en) * | 1975-12-29 | 1980-08-05 | Smith Kline & French Laboratories Limited | Heterocyclic alkyl 4-pyrimidones |
MW5076A1 (en) | 1975-12-29 | 1978-02-08 | Smith Kline French Lab | Pharmacologicalle active compounds |
NZ186511A (en) * | 1977-03-19 | 1980-11-14 | Smith Kline French Lab | 3-substituted alkylamino-6-substituted alkyl-1,2,4-triazin-5-ones and pharmaceutical compositions 3-substituted thio-1,2,4-triazin-5-ones |
GB2001624B (en) * | 1977-04-20 | 1982-03-03 | Ici Ltd | Guanidine derivatives processes for their manufacture and pharmaceutical compositions containing them |
EP0003640B1 (de) * | 1978-01-18 | 1982-01-27 | Imperial Chemical Industries Plc | Antisekretorische Guanidinderivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate |
-
1979
- 1979-10-10 US US06/083,479 patent/US4374836A/en not_active Expired - Lifetime
- 1979-10-15 CA CA000337642A patent/CA1218066A/en not_active Expired
- 1979-10-15 AT AT79302212T patent/ATE4383T1/de not_active IP Right Cessation
- 1979-10-15 EP EP79302212A patent/EP0010894B1/de not_active Expired
- 1979-10-15 DE DE7979302212T patent/DE2966030D1/de not_active Expired
- 1979-10-16 JP JP13249079A patent/JPS5553288A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0010894B1 (de) | 1983-08-03 |
CA1218066A (en) | 1987-02-17 |
EP0010894A1 (de) | 1980-05-14 |
ATE4383T1 (de) | 1983-08-15 |
US4374836A (en) | 1983-02-22 |
JPS5553288A (en) | 1980-04-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |