DE2703109A1 - Biologisch wirksame amide - Google Patents

Biologisch wirksame amide

Info

Publication number
DE2703109A1
DE2703109A1 DE19772703109 DE2703109A DE2703109A1 DE 2703109 A1 DE2703109 A1 DE 2703109A1 DE 19772703109 DE19772703109 DE 19772703109 DE 2703109 A DE2703109 A DE 2703109A DE 2703109 A1 DE2703109 A1 DE 2703109A1
Authority
DE
Germany
Prior art keywords
radical
group
radicals
phe
giy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19772703109
Other languages
German (de)
English (en)
Inventor
Samuel Wilkinson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB2900/76A external-priority patent/GB1577114A/en
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of DE2703109A1 publication Critical patent/DE2703109A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE19772703109 1976-01-26 1977-01-26 Biologisch wirksame amide Ceased DE2703109A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB2900/76A GB1577114A (en) 1976-01-26 1976-01-26 Biologically active peptides
GB848176 1976-03-03
GB4882176 1976-11-23

Publications (1)

Publication Number Publication Date
DE2703109A1 true DE2703109A1 (de) 1977-08-04

Family

ID=27254145

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19772703109 Ceased DE2703109A1 (de) 1976-01-26 1977-01-26 Biologisch wirksame amide

Country Status (11)

Country Link
JP (1) JPS5291839A (enrdf_load_stackoverflow)
CH (1) CH644352A5 (enrdf_load_stackoverflow)
DE (1) DE2703109A1 (enrdf_load_stackoverflow)
DK (1) DK33177A (enrdf_load_stackoverflow)
ES (1) ES455365A1 (enrdf_load_stackoverflow)
FI (1) FI70228C (enrdf_load_stackoverflow)
FR (1) FR2338925A1 (enrdf_load_stackoverflow)
HU (1) HU184704B (enrdf_load_stackoverflow)
IL (1) IL51332A (enrdf_load_stackoverflow)
NL (1) NL7700785A (enrdf_load_stackoverflow)
SE (1) SE7708404L (enrdf_load_stackoverflow)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4247543A (en) * 1979-04-09 1981-01-27 Sandoz Ltd. Organic compounds
US4261888A (en) * 1976-04-12 1981-04-14 Sandoz Ltd. Organic compounds
EP0029300A1 (en) * 1979-11-05 1981-05-27 Addiction Research Foundation Polypeptides, antisera containing them and methods of their use
US4407794A (en) * 1980-08-08 1983-10-04 Centre National De La Recherche Scientifique (Cnrs) Peptides and therapeutic applications thereof
EP0644772A4 (en) * 1992-11-12 1997-01-29 Biomeasure Inc OPIOID PEPTIDES.
EP0614913A3 (en) * 1984-11-09 1997-06-04 Eisai Co Ltd Dynorphin derivatives.
US10278957B2 (en) 2017-09-11 2019-05-07 Protagonist Therapeutics, Inc. Opioid agonist peptides and uses thereof

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4003000A (en) * 1975-05-27 1977-01-11 Sperry Rand Corporation Sinusoidal oscillator with electronically variable frequency
FR2359817A1 (fr) * 1976-07-27 1978-02-24 Reckitt & Colmann Prod Ltd Nouveaux peptides, leur procede de preparation et composition therapeutique les contenant
GB1532148A (en) * 1976-08-09 1978-11-15 Searle & Co 1-substituted enkepholin derivatives
HU178001B (en) * 1976-09-16 1982-02-28 Gyogyszekutato Intezet Process for preparing new pentapeptides with morphine-like activity and derivatives thereof
DE2819277A1 (de) * 1977-05-16 1978-11-23 Sandoz Ag Neue polypeptidderivate, ihre herstellung und verwendung
GB2000784B (en) * 1977-07-05 1982-01-20 American Home Prod Analgesic polypetide
DE2862327D1 (en) * 1977-07-22 1983-11-10 Wellcome Found Pentapeptide-n-alkylamides and their acid addition salts, methods for preparation of these compounds and pharmaceutical formulations containing them
US4264491A (en) * 1977-10-03 1981-04-28 Eli Lilly And Company Analgesic compounds
HU182051B (en) * 1978-05-02 1983-12-28 Takeda Chemical Industries Ltd Process for preparing tetrapeptide-hydrazyde derivatives
US4278596A (en) * 1978-08-08 1981-07-14 American Home Products Corporation Analgesic pentapeptides
CA1175810A (en) * 1979-03-30 1984-10-09 Frank A. Momany Synthetic peptides having pituitary growth hormone releasing activity
DE3163199D1 (en) * 1980-07-17 1984-05-24 Sandoz Ag Novel pentapeptides, processes for their production, pharmaceutical compositions comprising said pentapeptides and their use
BR8208035A (pt) * 1981-12-28 1983-11-22 Beckman Instruments Inc Peptideos sinteticos tendo atividade liberadora de hormonio do crescimento da pituitaria
US4491541A (en) * 1982-11-10 1985-01-01 Farmitalia Carlo Erba Peptides
AU618029B2 (en) * 1987-11-02 1991-12-12 Imperial Chemical Industries Plc Polypeptide compounds
WO2010120691A2 (en) * 2009-04-13 2010-10-21 Elc Management Llc Methionine sulfoxide peptide, compositions and methods of use

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261888A (en) * 1976-04-12 1981-04-14 Sandoz Ltd. Organic compounds
US4247543A (en) * 1979-04-09 1981-01-27 Sandoz Ltd. Organic compounds
EP0029300A1 (en) * 1979-11-05 1981-05-27 Addiction Research Foundation Polypeptides, antisera containing them and methods of their use
US4407794A (en) * 1980-08-08 1983-10-04 Centre National De La Recherche Scientifique (Cnrs) Peptides and therapeutic applications thereof
EP0614913A3 (en) * 1984-11-09 1997-06-04 Eisai Co Ltd Dynorphin derivatives.
EP0644772A4 (en) * 1992-11-12 1997-01-29 Biomeasure Inc OPIOID PEPTIDES.
US5663295A (en) * 1992-11-12 1997-09-02 Biomeasure Inc. Opioid peptides
US10278957B2 (en) 2017-09-11 2019-05-07 Protagonist Therapeutics, Inc. Opioid agonist peptides and uses thereof
US10729676B2 (en) 2017-09-11 2020-08-04 Protagonist Theraputics, Inc. Opioid agonist peptides and uses thereof

Also Published As

Publication number Publication date
CH644352A5 (en) 1984-07-31
NL7700785A (nl) 1977-07-28
SE7708404L (sv) 1977-07-27
IL51332A0 (en) 1977-03-31
JPS5291839A (en) 1977-08-02
ES455365A1 (es) 1978-05-16
FI770254A7 (enrdf_load_stackoverflow) 1977-07-27
HU184704B (en) 1984-10-29
FR2338925A1 (fr) 1977-08-19
FR2338925B1 (enrdf_load_stackoverflow) 1980-08-08
IL51332A (en) 1980-09-16
DK33177A (da) 1977-07-27
FI70228C (fi) 1986-09-15
FI70228B (fi) 1986-02-28

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8131 Rejection