DE2546510A1 - Verfahren zur herstellung von 2,4-diamino-6-hydroxy-5-(3', 4', 5'- trimethoxybenzyl)-pyrimidin - Google Patents

Verfahren zur herstellung von 2,4-diamino-6-hydroxy-5-(3', 4', 5'- trimethoxybenzyl)-pyrimidin

Info

Publication number
DE2546510A1
DE2546510A1 DE19752546510 DE2546510A DE2546510A1 DE 2546510 A1 DE2546510 A1 DE 2546510A1 DE 19752546510 DE19752546510 DE 19752546510 DE 2546510 A DE2546510 A DE 2546510A DE 2546510 A1 DE2546510 A1 DE 2546510A1
Authority
DE
Germany
Prior art keywords
diamino
pyrimidine
formula
trimethoxybenzyl
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19752546510
Other languages
German (de)
English (en)
Inventor
Peter Bamberg
Ladislas Janos Sandor Vegh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra USA Inc
Original Assignee
Astra Pharmaceutical Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharmaceutical Products Inc filed Critical Astra Pharmaceutical Products Inc
Publication of DE2546510A1 publication Critical patent/DE2546510A1/de
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE19752546510 1974-10-21 1975-10-17 Verfahren zur herstellung von 2,4-diamino-6-hydroxy-5-(3', 4', 5'- trimethoxybenzyl)-pyrimidin Pending DE2546510A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7413202A SE400077B (sv) 1974-10-21 1974-10-21 Ett forfarande for framstellning av 2,4-diamino-5(3',4',5',-trimetoxibensyl)-pyrimidin

Publications (1)

Publication Number Publication Date
DE2546510A1 true DE2546510A1 (de) 1976-04-29

Family

ID=20322479

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752546510 Pending DE2546510A1 (de) 1974-10-21 1975-10-17 Verfahren zur herstellung von 2,4-diamino-6-hydroxy-5-(3', 4', 5'- trimethoxybenzyl)-pyrimidin

Country Status (13)

Country Link
JP (1) JPS5165776A (xx)
AT (1) AT343122B (xx)
BE (1) BE834694A (xx)
CH (1) CH599168A5 (xx)
DE (1) DE2546510A1 (xx)
DK (1) DK135375B (xx)
FI (1) FI752900A (xx)
FR (1) FR2299326A1 (xx)
GB (1) GB1526235A (xx)
LU (1) LU73620A1 (xx)
NL (1) NL7512341A (xx)
NO (1) NO753480L (xx)
SE (1) SE400077B (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4569996A (en) * 1982-07-30 1986-02-11 Smith Kline & French Laboratories Limited Process for preparing substituted pyrimidinones

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4569996A (en) * 1982-07-30 1986-02-11 Smith Kline & French Laboratories Limited Process for preparing substituted pyrimidinones

Also Published As

Publication number Publication date
DK135375B (da) 1977-04-18
DK135375C (xx) 1977-10-17
SE400077B (sv) 1978-03-13
NO753480L (xx) 1976-04-22
JPS5165776A (en) 1976-06-07
AT343122B (de) 1978-05-10
CH599168A5 (xx) 1978-05-12
GB1526235A (en) 1978-09-27
FR2299326A1 (fr) 1976-08-27
ATA788475A (de) 1977-09-15
BE834694A (fr) 1976-04-21
FR2299326B1 (xx) 1978-10-13
NL7512341A (nl) 1976-04-23
SE7413202L (sv) 1976-04-22
DK465375A (xx) 1976-04-22
FI752900A (xx) 1976-04-22
LU73620A1 (xx) 1976-08-19

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