DE2514537A1 - Verfahren zur stabilisierung von interferon - Google Patents

Verfahren zur stabilisierung von interferon

Info

Publication number
DE2514537A1
DE2514537A1 DE19752514537 DE2514537A DE2514537A1 DE 2514537 A1 DE2514537 A1 DE 2514537A1 DE 19752514537 DE19752514537 DE 19752514537 DE 2514537 A DE2514537 A DE 2514537A DE 2514537 A1 DE2514537 A1 DE 2514537A1
Authority
DE
Germany
Prior art keywords
interferon
solution
agent
urea
active agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19752514537
Other languages
German (de)
English (en)
Inventor
Pierre Marie Hendrik Fra Somer
William Edgar Stewart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stichting Rega VZW
Original Assignee
Stichting Rega VZW
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting Rega VZW filed Critical Stichting Rega VZW
Publication of DE2514537A1 publication Critical patent/DE2514537A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DE19752514537 1974-04-03 1975-04-03 Verfahren zur stabilisierung von interferon Withdrawn DE2514537A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7404589A NL7404589A (nl) 1974-04-03 1974-04-03 Werkwijze voor het stabiliseren van interferon.

Publications (1)

Publication Number Publication Date
DE2514537A1 true DE2514537A1 (de) 1975-10-09

Family

ID=19821109

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752514537 Withdrawn DE2514537A1 (de) 1974-04-03 1975-04-03 Verfahren zur stabilisierung von interferon

Country Status (11)

Country Link
US (1) US3981991A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5132725A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU7951275A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE826889A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2514537A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK139775A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI750951A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2266740B3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL7404589A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO751118L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE7503769L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0138087A1 (en) * 1983-09-20 1985-04-24 F. Hoffmann-La Roche Ag Immune interferon and method for its purification
EP0140127A1 (en) * 1983-09-20 1985-05-08 F. Hoffmann-La Roche Ag Process for the preparation of immune interferon

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4100150A (en) * 1975-11-04 1978-07-11 G. D. Searle & Co. Stabilization of interferon against mechanical stress using thioctic acid
FR2351665A1 (fr) * 1976-05-21 1977-12-16 Elf Aquitaine Procede de purification de preparations possedant notamment une activite interferon, preparations purifiees ainsi obtenues et leur application en tant que medicament
IN150740B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1978-11-24 1982-12-04 Hoffmann La Roche
US4503035B1 (en) * 1978-11-24 1996-03-19 Hoffmann La Roche Protein purification process and product
US6410697B1 (en) 1979-04-20 2002-06-25 Schering Corporation Process for purifying human leukocyte interferon
US4289689A (en) * 1980-03-14 1981-09-15 Hoffmann-La Roche Inc. Preparation of homogeneous human fibroblast interferon
US4252791A (en) * 1979-10-19 1981-02-24 The Medical College Of Wisconsin, Inc. Interferon stabilization
WO1986001723A1 (fr) * 1984-09-21 1986-03-27 Vsesojuzny Nauchno-Issledovatelsky Institut Osobo Procede de rectification d'interferon leukocytique humain
IE57069B1 (en) 1980-04-03 1992-04-22 Biogen Inc Dna sequences,recombinant dna molecules and processes for producing human fibroblast interferon
EP0305551A3 (en) * 1981-10-13 1990-01-10 Exovir, Inc. Pharmaceutical compositions for topical application
US5582824A (en) * 1981-10-19 1996-12-10 Genentech, Inc. Recombinant DES-CYS-TYR-CYS human immune interferon
JPS58167520A (ja) * 1982-03-27 1983-10-03 Sunstar Inc インタ−フエロン安定配合製剤
EP0080879B1 (en) * 1981-11-28 1986-10-01 Sunstar Kabushiki Kaisha Pharmaceutical composition containing interferon in stable state
US5702699A (en) * 1982-09-23 1997-12-30 Cetus Corporation Process for the recovery of lipophilic proteins
US4681930A (en) * 1983-09-20 1987-07-21 Hoffmann-La Roche Inc. Immune interferon and a method for its extraction and purification
JPS6079000A (ja) * 1983-10-04 1985-05-04 Takeda Chem Ind Ltd ヒトγ型インタ−フエロン単量体の製造法
MX9203641A (es) * 1983-12-16 1992-07-01 Genentech Inc Interferones gamma recombinantes que poseen estabilidad mejorada y metodos biotecnologicos para su obtencion.
US4855238A (en) 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
IL74093A0 (en) * 1984-01-23 1985-04-30 Takeda Chemical Industries Ltd Stable composition of gamma-interferon
JPS61277633A (ja) * 1985-05-31 1986-12-08 Toray Ind Inc インタ−フエロン組成物
JP2577742B2 (ja) * 1986-07-18 1997-02-05 中外製薬株式会社 安定な顆粒球コロニ−刺激因子含有製剤
US4950470A (en) * 1986-10-06 1990-08-21 Board Of Regents, The University Of Texas System Methods and compositions employing interferon-gamma
US5165921A (en) * 1989-01-23 1992-11-24 National Geno Sciences, Inc. Method for treating condyloma acuminatum with interferon
US5236707A (en) * 1991-11-08 1993-08-17 Dallas Biotherapeutics, Inc. Stabilization of human interferon
US6399296B1 (en) * 1994-07-20 2002-06-04 The General Hospital Corporation Interaction trap systems for detecting protein interactions
GB0002660D0 (en) * 2000-02-04 2000-03-29 Biomade B V Method of stabilizing a hydrophobin-containing solution and a method of coatinga surface with a hydrophobin
AR034749A1 (es) * 2001-07-09 2004-03-17 Schering Ag Formulaciones de interferon beta humano

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0138087A1 (en) * 1983-09-20 1985-04-24 F. Hoffmann-La Roche Ag Immune interferon and method for its purification
EP0140127A1 (en) * 1983-09-20 1985-05-08 F. Hoffmann-La Roche Ag Process for the preparation of immune interferon

Also Published As

Publication number Publication date
DK139775A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-10-04
BE826889A (nl) 1975-09-22
AU7951275A (en) 1976-09-30
NO751118L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-10-06
US3981991A (en) 1976-09-21
FR2266740A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-10-31
SE7503769L (sv) 1975-10-06
NL7404589A (nl) 1975-10-07
JPS5132725A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1976-03-19
FI750951A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-10-04
FR2266740B3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-12-16

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Legal Events

Date Code Title Description
8141 Disposal/no request for examination
8180 Miscellaneous part 1

Free format text: KURZFRISTIGE WIEDEREINSETZUNG WEGEN FALSCH VEROEFFENTLICHTEM ERLEDIGUNGSGRUND. DIE VEROEFFFENTLICHUNG DES ZUTREFFENDEN ERLEDIGUNGSGRUNDES ERFOLGT IM NAECHSTEN PATENTBLATT.

8139 Disposal/non-payment of the annual fee