DE2505755A1 - Mittel zum heben des blutcalciumgehaltes bei tieren und verfahren zu dessen herstellung - Google Patents
Mittel zum heben des blutcalciumgehaltes bei tieren und verfahren zu dessen herstellungInfo
- Publication number
- DE2505755A1 DE2505755A1 DE19752505755 DE2505755A DE2505755A1 DE 2505755 A1 DE2505755 A1 DE 2505755A1 DE 19752505755 DE19752505755 DE 19752505755 DE 2505755 A DE2505755 A DE 2505755A DE 2505755 A1 DE2505755 A1 DE 2505755A1
- Authority
- DE
- Germany
- Prior art keywords
- gel
- forming polymer
- calcium
- calcium chloride
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000011575 calcium Substances 0.000 title claims description 39
- 229910052791 calcium Inorganic materials 0.000 title claims description 39
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title claims description 38
- 238000000034 method Methods 0.000 title claims description 15
- 241001465754 Metazoa Species 0.000 title claims description 13
- 210000004369 blood Anatomy 0.000 title claims description 13
- 239000008280 blood Substances 0.000 title claims description 13
- 238000004519 manufacturing process Methods 0.000 title description 3
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 25
- 229920000642 polymer Polymers 0.000 claims description 21
- 239000001110 calcium chloride Substances 0.000 claims description 20
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 18
- 239000000203 mixture Substances 0.000 claims description 17
- 239000003795 chemical substances by application Substances 0.000 claims description 13
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 9
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 9
- 229920002125 Sokalan® Polymers 0.000 claims description 6
- 238000010438 heat treatment Methods 0.000 claims description 6
- 238000002360 preparation method Methods 0.000 claims description 6
- 239000002202 Polyethylene glycol Substances 0.000 claims description 5
- 229920001223 polyethylene glycol Polymers 0.000 claims description 5
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 3
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims description 3
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 150000004687 hexahydrates Chemical class 0.000 claims description 2
- 210000002966 serum Anatomy 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- 241000283690 Bos taurus Species 0.000 description 5
- 230000006735 deficit Effects 0.000 description 5
- 210000000988 bone and bone Anatomy 0.000 description 4
- QHFQAJHNDKBRBO-UHFFFAOYSA-L calcium chloride hexahydrate Chemical compound O.O.O.O.O.O.[Cl-].[Cl-].[Ca+2] QHFQAJHNDKBRBO-UHFFFAOYSA-L 0.000 description 4
- 239000007864 aqueous solution Substances 0.000 description 3
- 150000002148 esters Chemical class 0.000 description 3
- 210000000936 intestine Anatomy 0.000 description 3
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- 208000009043 Chemical Burns Diseases 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000006116 polymerization reaction Methods 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 241000283086 Equidae Species 0.000 description 1
- 101000635799 Homo sapiens Run domain Beclin-1-interacting and cysteine-rich domain-containing protein Proteins 0.000 description 1
- 208000007542 Paresis Diseases 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 102100030852 Run domain Beclin-1-interacting and cysteine-rich domain-containing protein Human genes 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- 208000003217 Tetany Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000012888 bovine serum Substances 0.000 description 1
- 150000001669 calcium Chemical class 0.000 description 1
- 229940072020 calcium borogluconate Drugs 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 229940043430 calcium compound Drugs 0.000 description 1
- 150000001674 calcium compounds Chemical class 0.000 description 1
- 230000003913 calcium metabolism Effects 0.000 description 1
- SSKRIDIHZLFJCG-UHFFFAOYSA-L calcium;2,3-dihydroxy-3-[2-hydroxy-5-(hydroxymethyl)-1,3,2-dioxaborolan-4-yl]propanoate Chemical compound [Ca+2].OCC1OB(O)OC1C(O)C(O)C([O-])=O.OCC1OB(O)OC1C(O)C(O)C([O-])=O SSKRIDIHZLFJCG-UHFFFAOYSA-L 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 230000006651 lactation Effects 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 208000005368 osteomalacia Diseases 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 208000007442 rickets Diseases 0.000 description 1
- 210000004767 rumen Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT114174A AT326406B (de) | 1974-02-13 | 1974-02-13 | Verfahren zur herstellung eines mittels zum heben des blutcalciumgehaltes bei tieren |
| AT561774A AT332161B (de) | 1974-07-08 | 1974-07-08 | Verfahren zur herstellung eines mittels zum heben des blutcalciumgehaltes bei tieren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE2505755A1 true DE2505755A1 (de) | 1975-08-14 |
Family
ID=25595010
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE19752505755 Withdrawn DE2505755A1 (de) | 1974-02-13 | 1975-02-12 | Mittel zum heben des blutcalciumgehaltes bei tieren und verfahren zu dessen herstellung |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US3996351A (https=) |
| CA (1) | CA1045551A (https=) |
| DE (1) | DE2505755A1 (https=) |
| FR (1) | FR2272682A1 (https=) |
| GB (1) | GB1469224A (https=) |
| NL (1) | NL7501601A (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0101849A1 (de) | 1982-07-28 | 1984-03-07 | Algina Aktiengesellschaft | Arzneimittel, Calciummischsalze von polymeren, anionischen Carbonsäuren und/oder ihren Schwefelsäureestern, Verfahren zu ihrer Herstellung und ihre Verwendung |
| EP0386441A1 (en) * | 1989-02-09 | 1990-09-12 | Diamond Scientific Co. | Calcium therapy treatment for milk fever |
| EP0719548A1 (en) * | 1994-12-29 | 1996-07-03 | McNEIL-PPC, INC. | Gelling agent for polyethylene glycol |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4451389A (en) * | 1980-05-22 | 1984-05-29 | Phillips Petroleum Company | Aqueous gels |
| US4321968A (en) * | 1980-05-22 | 1982-03-30 | Phillips Petroleum Company | Methods of using aqueous gels |
| EP0449810B1 (en) * | 1988-12-23 | 1993-03-31 | Boehringer Ingelheim Agrovet A/S | Calcium chloride containing preparation for the prevention or the treatment of hypocalcemia in ruminants |
| US5395622A (en) * | 1988-12-23 | 1995-03-07 | Boehringer Ingelheim Agrovet A/S | Calcium chloride containing preparation for the prevention or the treatment of hypocalcemia in ruminants |
| IT1312325B1 (it) * | 1999-05-25 | 2002-04-15 | M Soda Sa | Microgranulo per l'alimentazione animale, particolarmente idoneo perintegrare mangimi con sali di calcio. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3356570A (en) * | 1964-11-27 | 1967-12-05 | Trustees Of Barnes Hospital | Composition for treating shock |
| FR7932M (https=) * | 1968-09-30 | 1970-05-19 | ||
| US3538214A (en) * | 1969-04-22 | 1970-11-03 | Merck & Co Inc | Controlled release medicinal tablets |
| US3608063A (en) * | 1969-08-15 | 1971-09-21 | Gilbert S Banker | Molecular drug entrapment process and compositions |
| US3640741A (en) * | 1970-02-24 | 1972-02-08 | Hollister Inc | Composition containing gel |
-
1975
- 1975-01-30 US US05/545,419 patent/US3996351A/en not_active Expired - Lifetime
- 1975-01-31 CA CA219,172A patent/CA1045551A/en not_active Expired
- 1975-02-07 FR FR7503804A patent/FR2272682A1/fr active Pending
- 1975-02-11 NL NL7501601A patent/NL7501601A/xx not_active Application Discontinuation
- 1975-02-12 DE DE19752505755 patent/DE2505755A1/de not_active Withdrawn
- 1975-02-13 GB GB618275A patent/GB1469224A/en not_active Expired
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0101849A1 (de) | 1982-07-28 | 1984-03-07 | Algina Aktiengesellschaft | Arzneimittel, Calciummischsalze von polymeren, anionischen Carbonsäuren und/oder ihren Schwefelsäureestern, Verfahren zu ihrer Herstellung und ihre Verwendung |
| EP0386441A1 (en) * | 1989-02-09 | 1990-09-12 | Diamond Scientific Co. | Calcium therapy treatment for milk fever |
| EP0719548A1 (en) * | 1994-12-29 | 1996-07-03 | McNEIL-PPC, INC. | Gelling agent for polyethylene glycol |
| US5660859A (en) * | 1994-12-29 | 1997-08-26 | Mcneil-Ppc, Inc. | Gelling agent for polyethylene glycol |
| US5840337A (en) * | 1994-12-29 | 1998-11-24 | Mcneil-Ppc, Inc. | Gelling agent for polyethylene gylcol |
Also Published As
| Publication number | Publication date |
|---|---|
| GB1469224A (en) | 1977-04-06 |
| US3996351A (en) | 1976-12-07 |
| NL7501601A (nl) | 1975-08-15 |
| CA1045551A (en) | 1979-01-02 |
| FR2272682A1 (https=) | 1975-12-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8110 | Request for examination paragraph 44 | ||
| 8139 | Disposal/non-payment of the annual fee |