DE2503436A1 - 2-substituierte 4,5-diphenylthiazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel - Google Patents

2-substituierte 4,5-diphenylthiazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Info

Publication number
DE2503436A1
DE2503436A1 DE19752503436 DE2503436A DE2503436A1 DE 2503436 A1 DE2503436 A1 DE 2503436A1 DE 19752503436 DE19752503436 DE 19752503436 DE 2503436 A DE2503436 A DE 2503436A DE 2503436 A1 DE2503436 A1 DE 2503436A1
Authority
DE
Germany
Prior art keywords
diphenylthiazole
formula
general formula
compounds
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19752503436
Other languages
German (de)
English (en)
Inventor
Enzo Marchetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Serono Laboratories Inc
Original Assignee
Serono Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serono Laboratories Inc filed Critical Serono Laboratories Inc
Publication of DE2503436A1 publication Critical patent/DE2503436A1/de
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/42Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19752503436 1974-01-31 1975-01-28 2-substituierte 4,5-diphenylthiazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel Ceased DE2503436A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH137774A CH587836A5 (US20100154141A1-20100624-C00001.png) 1974-01-31 1974-01-31

Publications (1)

Publication Number Publication Date
DE2503436A1 true DE2503436A1 (de) 1975-08-07

Family

ID=4208998

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752503436 Ceased DE2503436A1 (de) 1974-01-31 1975-01-28 2-substituierte 4,5-diphenylthiazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Country Status (15)

Country Link
JP (1) JPS50121269A (US20100154141A1-20100624-C00001.png)
AT (1) AT339898B (US20100154141A1-20100624-C00001.png)
BE (1) BE825097A (US20100154141A1-20100624-C00001.png)
CA (1) CA1036600A (US20100154141A1-20100624-C00001.png)
CH (1) CH587836A5 (US20100154141A1-20100624-C00001.png)
DE (1) DE2503436A1 (US20100154141A1-20100624-C00001.png)
DK (1) DK33175A (US20100154141A1-20100624-C00001.png)
ES (1) ES434151A1 (US20100154141A1-20100624-C00001.png)
FR (1) FR2259603B1 (US20100154141A1-20100624-C00001.png)
GB (1) GB1490771A (US20100154141A1-20100624-C00001.png)
IL (1) IL46476A (US20100154141A1-20100624-C00001.png)
NL (1) NL7501086A (US20100154141A1-20100624-C00001.png)
NO (1) NO750278L (US20100154141A1-20100624-C00001.png)
SE (1) SE7501010L (US20100154141A1-20100624-C00001.png)
ZA (1) ZA75494B (US20100154141A1-20100624-C00001.png)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2836742A1 (de) * 1977-09-28 1979-04-05 Upjohn Co Thiazole, verwendung derselben und diese enthaltende arzneimittel
WO1992015570A1 (fr) * 1991-03-07 1992-09-17 Hisamitsu Pharmaceutical Co., Inc. Nouveau derive de diphenylthiazole
EP2196459A1 (en) * 2007-09-28 2010-06-16 Takeda Pharmaceutical Company Limited 5-membered heterocyclic compound

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0753666B2 (ja) * 1987-09-14 1995-06-07 久光製薬株式会社 置換ジフェニルチアゾール誘導体からなる抗炎症剤
CA2012716A1 (en) * 1989-03-22 1990-09-22 Akito Tanaka Thiazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same
RU2332412C2 (ru) 2003-02-07 2008-08-27 Дайити Фармасьютикал Ко., Лтд. Производные пиразола

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2836742A1 (de) * 1977-09-28 1979-04-05 Upjohn Co Thiazole, verwendung derselben und diese enthaltende arzneimittel
WO1992015570A1 (fr) * 1991-03-07 1992-09-17 Hisamitsu Pharmaceutical Co., Inc. Nouveau derive de diphenylthiazole
EP2196459A1 (en) * 2007-09-28 2010-06-16 Takeda Pharmaceutical Company Limited 5-membered heterocyclic compound
EP2196459A4 (en) * 2007-09-28 2011-06-15 Takeda Pharmaceutical 5-GROUND HETEROCYCLIC COMPOUND
US8334301B2 (en) 2007-09-28 2012-12-18 Takeda Pharmaceutical Company Limited 5-Membered heterocyclic compound
EP3162798A1 (en) * 2007-09-28 2017-05-03 Takeda Pharmaceutical Company Limited 5-membered heterocyclic compound

Also Published As

Publication number Publication date
NO750278L (US20100154141A1-20100624-C00001.png) 1975-08-25
IL46476A (en) 1978-12-17
FR2259603B1 (US20100154141A1-20100624-C00001.png) 1978-07-21
ZA75494B (en) 1976-01-28
AT339898B (de) 1977-11-10
CH587836A5 (US20100154141A1-20100624-C00001.png) 1977-05-13
SE7501010L (US20100154141A1-20100624-C00001.png) 1975-08-01
FR2259603A1 (US20100154141A1-20100624-C00001.png) 1975-08-29
AU7747875A (en) 1976-07-22
BE825097A (fr) 1975-07-31
ATA55975A (de) 1977-03-15
GB1490771A (en) 1977-11-02
CA1036600A (en) 1978-08-15
NL7501086A (nl) 1975-08-04
DK33175A (US20100154141A1-20100624-C00001.png) 1975-09-29
ES434151A1 (es) 1976-12-01
IL46476A0 (en) 1975-04-25
JPS50121269A (US20100154141A1-20100624-C00001.png) 1975-09-23

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Legal Events

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8110 Request for examination paragraph 44
8131 Rejection