DE2502621C3 - - Google Patents

Info

Publication number
DE2502621C3
DE2502621C3 DE19752502621 DE2502621A DE2502621C3 DE 2502621 C3 DE2502621 C3 DE 2502621C3 DE 19752502621 DE19752502621 DE 19752502621 DE 2502621 A DE2502621 A DE 2502621A DE 2502621 C3 DE2502621 C3 DE 2502621C3
Authority
DE
Germany
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE19752502621
Other versions
DE2502621A1 (en
DE2502621B2 (en
Inventor
Hans Prof. Dr. Randwick Coster (Australien)
Guenter Dr. Pilwat
Ulrich Dr. Zimmermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BAYERISCHE JULIUS-MAXIMILIANS-UNIVERSITAET WUERZBU
Original Assignee
Kernforschungsanlage Juelich 5170 Juelich GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kernforschungsanlage Juelich 5170 Juelich GmbH filed Critical Kernforschungsanlage Juelich 5170 Juelich GmbH
Priority to DE19752502621 priority Critical patent/DE2502621C3/de
Publication of DE2502621A1 publication Critical patent/DE2502621A1/en
Publication of DE2502621B2 publication Critical patent/DE2502621B2/en
Application granted granted Critical
Publication of DE2502621C3 publication Critical patent/DE2502621C3/de
Application status is Expired legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/48707Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48728Investigating individual cells, e.g. by patch clamp, voltage clamp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radiowaves
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/12Coulter-counters
    • G01N15/1245Devices using more than one aperture
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R27/00Arrangements for measuring resistance, reactance, impedance, or electric characteristics derived therefrom
    • G01R27/02Measuring real or complex resistance, reactance, impedance, or other two-pole characteristics derived therefrom, e.g. time constant
    • G01R27/26Measuring inductance or capacitance; Measuring quality factor, e.g. by using the resonance method; Measuring loss factor; Measuring dielectric constants ; Measuring impedance or related variables
    • G01R27/2617Measuring dielectric properties, e.g. constants
    • G01R27/2635Sample holders, electrodes or excitation arrangements, e.g. sensors or measuring cells
    • G01R27/2658Cavities, resonators, free space arrangements, reflexion or interference arrangements
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N2015/0065Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials biological, e.g. blood
    • G01N2015/0073Red blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N2015/1006Investigating individual particles for cytology
DE19752502621 1975-01-23 1975-01-23 Expired DE2502621C3 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19752502621 DE2502621C3 (en) 1975-01-23 1975-01-23

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE19752502621 DE2502621C3 (en) 1975-01-23 1975-01-23
CH1463175A CH594888A5 (en) 1975-01-23 1975-11-12
US05/651,337 US4055799A (en) 1975-01-23 1976-01-22 Method of and device for measuring elastic and di-electric properties of the diaphragm of living cells
JP551276A JPS6013140B2 (en) 1975-01-23 1976-01-22
FR7601679A FR2298797B1 (en) 1975-01-23 1976-01-22

Publications (3)

Publication Number Publication Date
DE2502621A1 DE2502621A1 (en) 1976-08-05
DE2502621B2 DE2502621B2 (en) 1978-01-12
DE2502621C3 true DE2502621C3 (en) 1978-09-14

Family

ID=5937086

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752502621 Expired DE2502621C3 (en) 1975-01-23 1975-01-23

Country Status (5)

Country Link
US (1) US4055799A (en)
JP (1) JPS6013140B2 (en)
CH (1) CH594888A5 (en)
DE (1) DE2502621C3 (en)
FR (1) FR2298797B1 (en)

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US4472506A (en) * 1981-01-13 1984-09-18 Liburdy Robert P Method for determining cell membrane dielectric breakdown
US4368423A (en) * 1981-01-13 1983-01-11 Liburdy Robert P Apparatus for determining cell membrane dielectric breakdown
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US5272081A (en) * 1982-05-10 1993-12-21 Bar-Ilan University System and methods for cell selection
US4528270A (en) * 1982-11-02 1985-07-09 Kabushiki Kaisya Advance Kaihatsu Kenkyujo Electrochemical method for detection and classification of microbial cell
FR2569477B1 (en) * 1984-08-24 1987-01-02 Descartes Universite Rene An apparatus and method for the determination of the deformability of red blood cells
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US5389069A (en) * 1988-01-21 1995-02-14 Massachusetts Institute Of Technology Method and apparatus for in vivo electroporation of remote cells and tissue
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JP2993982B2 (en) * 1988-10-21 1999-12-27 モレキユラー デヴアイシズ コーポレイシヨン Method and apparatus for detecting the effects of cell agent on living cells
GB2232769B (en) * 1989-06-13 1994-06-22 Timothy Charles Fisher Counting and volume measurement of particles and biological cells,and determination of their deformability
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AUPM851694A0 (en) * 1994-09-30 1994-10-27 Barsamian, Sergei T New methods for diagnosis, detection of cell abnormalities and morphology of living systems
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US5983131A (en) * 1995-08-11 1999-11-09 Massachusetts Institute Of Technology Apparatus and method for electroporation of tissue
US6010613A (en) * 1995-12-08 2000-01-04 Cyto Pulse Sciences, Inc. Method of treating materials with pulsed electrical fields
AT366418T (en) 1996-04-25 2007-07-15 Bioarray Solutions Ltd Light-regulated, electrokinetic composition of particles of surfaces
US6387707B1 (en) * 1996-04-25 2002-05-14 Bioarray Solutions Array Cytometry
US5911223A (en) * 1996-08-09 1999-06-15 Massachusetts Institute Of Technology Introduction of modifying agents into skin by electroporation
US6085115A (en) * 1997-05-22 2000-07-04 Massachusetts Institite Of Technology Biopotential measurement including electroporation of tissue surface
AT258980T (en) * 1997-06-10 2004-02-15 Cyto Pulse Sciences Inc A method and apparatus for the treatment of different material with electric fields landmark
US6163719A (en) * 1997-09-09 2000-12-19 Sherman; Adam Jacob Biological membrane voltage estimator
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US20020144905A1 (en) 1997-12-17 2002-10-10 Christian Schmidt Sample positioning and analysis system
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US7067046B2 (en) 2000-08-04 2006-06-27 Essen Instruments, Inc. System for rapid chemical activation in high-throughput electrophysiological measurements
US6488829B1 (en) * 1999-08-05 2002-12-03 Essen Instruments Inc High-throughput electrophysiological measurement apparatus
US7270730B2 (en) * 2000-08-04 2007-09-18 Essen Instruments, Inc. High-throughput electrophysiological measurement system
DE19946458C2 (en) * 1999-09-28 2002-10-24 Fraunhofer Ges Forschung Apparatus and method for characterizing spheroids
US6682649B1 (en) * 1999-10-01 2004-01-27 Sophion Bioscience A/S Substrate and a method for determining and/or monitoring electrophysiological properties of ion channels
GB9930719D0 (en) * 1999-12-24 2000-02-16 Central Research Lab Ltd Apparatus for and method of making electrical measurements on an object in a m edium
GB9930718D0 (en) * 1999-12-24 2000-02-16 Central Research Lab Ltd Apparatus for and method of making electrical measurements on objects
CA2413978C (en) 2000-06-21 2008-12-16 Bioarray Solutions, Ltd. Multianalyte molecular analysis
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
EP1178315A1 (en) * 2000-07-31 2002-02-06 Albrecht Dr.med. Priv.Doz. Lepple-Wienhues Method and apparatus for examining cells using the patch clamp method
US7968305B2 (en) * 2001-03-24 2011-06-28 Aviva Biosciences Corporation Biochips including ion transport detecting structures and methods of use
US20050058990A1 (en) * 2001-03-24 2005-03-17 Antonio Guia Biochip devices for ion transport measurement, methods of manufacture, and methods of use
US20060029955A1 (en) * 2001-03-24 2006-02-09 Antonio Guia High-density ion transport measurement biochip devices and methods
US20050196746A1 (en) * 2001-03-24 2005-09-08 Jia Xu High-density ion transport measurement biochip devices and methods
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
WO2003011553A1 (en) * 2001-07-31 2003-02-13 Massachusetts Institute Of Technology On-chip membrane maker
CN100494395C (en) 2001-10-15 2009-06-03 生物芯片技术有限公司 polymorphic locus multiplexed analysis by concurrent probing and enzyme-mediated detection
US20040146849A1 (en) * 2002-01-24 2004-07-29 Mingxian Huang Biochips including ion transport detecting structures and methods of use
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US20050009004A1 (en) * 2002-05-04 2005-01-13 Jia Xu Apparatus including ion transport detecting structures and methods of use
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GB1262749A (en) * 1969-02-24 1972-02-02 Nat Res Dev Methods and apparatus for determining the condition of food
US3772593A (en) * 1971-11-03 1973-11-13 P Sidhu Resistance measurement system

Also Published As

Publication number Publication date
DE2502621A1 (en) 1976-08-05
DE2502621B2 (en) 1978-01-12
JPS5197495A (en) 1976-08-27
FR2298797B1 (en) 1980-01-11
FR2298797A1 (en) 1976-08-20
CH594888A5 (en) 1978-01-31
JPS6013140B2 (en) 1985-04-05
US4055799A (en) 1977-10-25

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)
8327 Change in the person/name/address of the patent owner

Owner name: BAYERISCHE JULIUS-MAXIMILIANS-UNIVERSITAET WUERZBU

8339 Ceased/non-payment of the annual fee