DE2414146A1 - PROCEDURE FOR DETERMINING THE TOXIC METABOLIZER PRODUCTS FROM MOLD - Google Patents

PROCEDURE FOR DETERMINING THE TOXIC METABOLIZER PRODUCTS FROM MOLD

Info

Publication number
DE2414146A1
DE2414146A1 DE2414146A DE2414146A DE2414146A1 DE 2414146 A1 DE2414146 A1 DE 2414146A1 DE 2414146 A DE2414146 A DE 2414146A DE 2414146 A DE2414146 A DE 2414146A DE 2414146 A1 DE2414146 A1 DE 2414146A1
Authority
DE
Germany
Prior art keywords
ethylene oxide
toxic
mold
mixture
products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE2414146A
Other languages
German (de)
Inventor
Gero E Dr Mayr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Deutsche Gesellschaft fuer Schadingbekampfung GmbH
Original Assignee
Deutsche Gesellschaft fuer Schadingbekampfung GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsche Gesellschaft fuer Schadingbekampfung GmbH filed Critical Deutsche Gesellschaft fuer Schadingbekampfung GmbH
Priority to DE2414146A priority Critical patent/DE2414146A1/en
Priority to SE7404642A priority patent/SE414266B/en
Priority to CS2508A priority patent/CS172882B2/cs
Priority to DK195074A priority patent/DK195074A/da
Priority to AT291174A priority patent/AT349875B/en
Priority to NO741303A priority patent/NO741303L/no
Priority to HUDE846A priority patent/HU167434B/hu
Priority to YU01030/74A priority patent/YU103074A/en
Priority to CH523974A priority patent/CH568023A5/xx
Priority to ES425401A priority patent/ES425401A1/en
Priority to PL1974170485A priority patent/PL88731B1/pl
Priority to IT68290/74A priority patent/IT1011770B/en
Priority to JP4641674A priority patent/JPS5337419B2/ja
Priority to FI1295/74A priority patent/FI129574A/fi
Priority to NL7406365A priority patent/NL7406365A/en
Priority to ZA00743678A priority patent/ZA743678B/en
Priority to GB2560974A priority patent/GB1442466A/en
Priority to CY993A priority patent/CY993A/en
Priority to CA202,293A priority patent/CA1030396A/en
Priority to AU70269/74A priority patent/AU7026974A/en
Priority to FR7421664A priority patent/FR2264483B1/fr
Priority to BE145924A priority patent/BE816904A/en
Publication of DE2414146A1 publication Critical patent/DE2414146A1/en
Priority to TR19642A priority patent/TR19642A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3409—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of gases, e.g. fumigation; Compositions or apparatus therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
    • A23L5/27—Removal of unwanted matter, e.g. deodorisation or detoxification by chemical treatment, by adsorption or by absorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fodder In General (AREA)
  • Beans For Foods Or Fodder (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Soy Sauces And Products Related Thereto (AREA)
  • Catching Or Destruction (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)

Description

Deutsche Gesellschaft für Schädlingsbekämpfung mbH, 6000 Frankfurt am Main, Neue Mainzer Straße 1German Pest Control Society, 6000 Frankfurt am Main, Neue Mainzer Strasse 1

Verfahren zum Unschädlichmachen der giftigen Stoffwechselprodukte von SchimmelpilzenProcess for rendering toxic metabolic products harmless of mold

Zahlreiche Schimmelpilze, wie beispielsweise Schimmelpilze der Gattungen Aspergillus und Penicillium, entwickeln sehr giftige StoffWechselprodukte, die als Mycotoxine bezeichnet werden. Diese Mycotoxine, von denen die verschiedenen Aflatoxine die bekanntesten sind, wirken sehr giftig gegenüber Warmblütern, wie Vögeln und Säugetieren.Numerous molds, such as molds of the genera Aspergillus and Penicillium, develop a lot toxic metabolic products called mycotoxins. These mycotoxins, of which the various Aflatoxins are the most well known, are very toxic to them Warm-blooded animals such as birds and mammals.

Es ist bekannt, Äthylenoxyd, Methylformiat oder ein Gemisch beider Gase zum Abtöten von Schimmelpilzen zu verwenden. Es war aber nicht bekannt, ob und wie diese Gase oder Gasgemische auf die Mycotoxine einwirken.It is known to use ethylene oxide, methyl formate or a mixture of both gases to kill molds. It however, it was not known whether and how these gases or gas mixtures affect the mycotoxins.

Aufgabe der Erfindung ist ein Verfahren zum Unschädlichmachen dieser giftigen Stoffwechselprodukte. Eine weitere Aufgabe der Erfindung ist ein solches Verfahren,durch welches auch die Schimmelpilze selbst abgetötet werden, so daß nach der erfindungsgemäßen Behandlung keine weiteren giftigen Stoffwechsel· produkte entstehen können.The object of the invention is a method for rendering these toxic metabolic products harmless. Another task of the Invention is such a method by which the Molds themselves are killed, so that no further toxic metabolism after the treatment according to the invention products can arise.

S09839/085 7S09839 / 085 7

24UH824UH8

Diese Aufgabe wird erfindungsgemäß dadurch gelöst, daß man Gegenstände, Stoffe oder Stoffgemische, welche die giftigen Stoffwechselprodukte von Schimmelpilzen enthalten, mit Äthylenoxyd, mit Methylformiat oder mit einem Gemisch beider Gase behandelt.According to the invention, this object is achieved in that Objects, substances or mixtures of substances which are toxic Contains metabolic products of mold, with ethylene oxide, with methyl formate or with a mixture of both gases treated.

Mit sehr gutem Erfolg wird ein Gasgemisch aus 40 bis 60 Volumprozent Methylformiat und 40 bis 60 Volumprozent Äthylenoxyd verwendet.A gas mixture of 40 to 60 percent by volume is very successful Methyl formate and 40 to 60 percent by volume ethylene oxide are used.

Zur Verringerung der Entzündungsgefahr ist es in manchen Fällen angebracht, zum Behandeln ein Gasgemisch zu verwenden, das außer Äthylenoxyd und/oder Methylformiat ein inertes Gas, wie Stickstoff oder Kohlendioxyd, enthält.To reduce the risk of ignition, in some cases it is appropriate to use a gas mixture for treatment, which, in addition to ethylene oxide and / or methyl formate, contains an inert gas such as nitrogen or carbon dioxide.

Aus Sicherheitsgründen ist es zweckmäßig, die Behandlung unter vermindertem Druck auszuführen. Bei Anwendung dieser Maßnahme wird verhindert, daß beim Undichtwerden des Behandlungsbehälter.s oder des Behandlungsraumes das Behandlungsgas nach außen austritt.For safety reasons, it is advisable to carry out the treatment under reduced pressure. When using this measure prevents the treatment gas from leaking if the treatment container or the treatment room becomes leaky exits outside.

Beispiel 1example 1

Erdnußexpeller, die durch den Befall mit einem Stamm von Aspergillus flavus je g 12yug Aflatoxin B- enthielten, wurden in eine Begasungskammer mit einem Inhalt von 11 Litern eingebracht. Die Kammer wurde bis auf einen Restdruck von 40 Torr evakuiert. Das flüssige Behandlungsmittel wurde in einem Wärmeaustauscher vergast und in die Begasungskammer geleitet.Peanut expellers which, due to the infestation with a strain of Aspergillus flavus, contained 12 g of aflatoxin B- per g placed in a gas chamber with a capacity of 11 liters. The chamber was down to a residual pressure of 40 torr evacuated. The liquid treatment agent was gasified in a heat exchanger and passed into the gas chamber.

5098 3 9/08575098 3 9/0857

24UH624UH6

Nach Ablauf der jeweiligen Begasungszeit wurde das Behandlungsmittel mit Hilfe einer Vakuumpumpe abgesaugt und sterile Frischluft wurde durch ein Wattefilter bis zum Druckausgleich in die Begasungskammer eingeführt.At the end of the respective fumigation time, the treatment agent was used Sucked off with the help of a vacuum pump and sterile fresh air was passed through a cotton wool filter until the pressure was equalized introduced into the gas chamber.

Zum Behandeln wurden folgende Gase verwendet:The following gases were used for treatment:

A ÄthylenoxydA ethylene oxide

B MethylformiatB methyl formate

C ein Gemisch von 50 VolumprozentC a mixture of 50 percent by volume

Äthylenoxyd und 50 VolumprozentEthylene oxide and 50 percent by volume

Methylformiat.Methyl formate.

Die Ergebnisse der Versuche sind in der nachstehenden Tabelle enthalten:The results of the tests are in the table below contain:

Begasungs
mittelFumigation
middle Menge des Be
gasungsmittels
g/m3 Amount of Be
gassing agent
g / m 3 Begasungs
dauer
-Stunden-Fumigation
duration
-Hours- Aflatoxin
/lg/gAflatoxin
/ lg / g 1212th AA. 750750 66th 11,511.5 BB. 750750 66th 1010 CC. 750750 66th 88th AA. 750750 1616 9,59.5 BB. 750750 1616 66th CC. 750750 1616 5,55.5 AA. 12501250 66th 88th BB. 12501250 66th 4,54.5 CC. 12501250 66th 44th AA. 12501250 1616 6,56.5 BB. 12501250 1616 44th CC. 12501250 1616 2,52.5

509839/0857509839/0857

- 4 ■ -- 4 ■ -

24UU624UU6

Der Nachweis und die quantitative Bestimmung des Aflatoxin wurde nach dem Verfahren von Hanssen und Hagedorn (ZUL 141 (1969) 3, 129-145) durchgeführt.The detection and quantitative determination of the aflatoxin was carried out using the method of Hanssen and Hagedorn (ZUL 141 (1969) 3, 129-145).

Beispiel 2Example 2

Erdnüsse mit einem starken Befall eines Stammes von Aspergillus flavus wurden nach dem Verfahren des Beispiels 1 behandelt. Die Ergebnisse sind in der nachstehenden Tabelle enthalten:Peanuts with a severe infestation of a strain of Aspergillus flavus were treated according to the method of Example 1. The results are given in the table below:

Begasungs
mittelFumigation
middle Menge des Be
gasungsmittels
g/m3 Amount of Be
gassing agent
g / m 3 Begasungs
dauer
-Stunden-Fumigation
duration
-Hours- Aflatoxin
yug/gAflatoxin
yug / g A
B
CA.
B.
C. 1250
1250
12501250
1250
1250 16
16
1616
16
16 168,0
115,0
76,0
32,5168.0
115.0
76.0
32.5

— 5 —- 5 -

5 098 3 9/08575 098 3 9/0857

Claims (4)

24UU6 Patentansprüche24UU6 claims 1. Verfahren zum ünschädlichmachen der giftigen Stoffwechselprodukte von Schimmelpilzen, dadurch gekennzeichnet, daß man Gegenstände, Stoffe oder Stoffgemische, welche diese Stoffwechselprodukte enthalten, mit Äthylenoxyd, mit Methylßiiformiat oder mit einem Gemisch beider Gase behandelt. 1. Process for rendering toxic metabolic products harmless of mold, characterized in that one objects, substances or mixtures of substances, which these Contain metabolic products, treated with ethylene oxide, with methyl formiformate or with a mixture of both gases. 2. Verfahren nach Anspruch 1, dadurch gekennzeichnet, daß man ein Gemisch von 40 bis 60 Volumprozent Methylformiat und 4O bis 6O Volumprozent Äthylenoxyd verwendet.2. The method according to claim 1, characterized in that a mixture of 40 to 60 percent by volume of methyl formate and 4O to 6O volume percent ethylene oxide used. 3. Verfahren nach Anspruch 1 oder 2, dadurch gekennzeichnet, daß man Gasgemisch verv/endet, das außer Äthylenoxyd und/oder Methylformiat ein inertes Gas enthält.3. The method according to claim 1 or 2, characterized in that one gas mixture verv / ends, the except ethylene oxide and / or methyl formate contains an inert gas. 4. Verfahren nach einem der Ansprüche 1 bis 3, dadurch gekennzeichnet, daß man die Behandlung unter vermindertem Druck ausführt.4. The method according to any one of claims 1 to 3, characterized in that that the treatment is carried out under reduced pressure. 509839/0857509839/0857 ORIGINAL fNSPECTORIGINAL fNSPECT
DE2414146A 1974-03-23 1974-03-23 PROCEDURE FOR DETERMINING THE TOXIC METABOLIZER PRODUCTS FROM MOLD Pending DE2414146A1 (en)

Priority Applications (23)

Application Number Priority Date Filing Date Title
DE2414146A DE2414146A1 (en) 1974-03-23 1974-03-23 PROCEDURE FOR DETERMINING THE TOXIC METABOLIZER PRODUCTS FROM MOLD
SE7404642A SE414266B (en) 1974-03-23 1974-04-05 USE OF ETHYLENOXIDE, METHYL FORMAT, OR MIXTURES THEREOF FOR THE INHIBITION OF MICOTOXINES FROM MOLD Fungi
CS2508A CS172882B2 (en) 1974-03-23 1974-04-08
DK195074A DK195074A (en) 1974-03-23 1974-04-08
AT291174A AT349875B (en) 1974-03-23 1974-04-08 METHOD FOR DAMAGING THE TOXIC METABOLIC PRODUCTS OF MOLD MUSHROOMS
NO741303A NO741303L (en) 1974-03-23 1974-04-08
HUDE846A HU167434B (en) 1974-03-23 1974-04-08
YU01030/74A YU103074A (en) 1974-03-23 1974-04-11 Process for neutralizing toxic metabolism products of moulds
CH523974A CH568023A5 (en) 1974-03-23 1974-04-16
ES425401A ES425401A1 (en) 1974-03-23 1974-04-17 Method for neutralizing the toxic metabolic products of mould fungi
PL1974170485A PL88731B1 (en) 1974-03-23 1974-04-19
IT68290/74A IT1011770B (en) 1974-03-23 1974-04-23 PROCEDURE FOR RENDERING TOXIC METABOLITES OF PHYCOMYCETS
JP4641674A JPS5337419B2 (en) 1974-03-23 1974-04-24
FI1295/74A FI129574A (en) 1974-03-23 1974-04-26
NL7406365A NL7406365A (en) 1974-03-23 1974-05-10 FUNGAL CONTROL.
ZA00743678A ZA743678B (en) 1974-03-23 1974-06-10 Method for neutralizing the toxic metabolic products of mould fungi
GB2560974A GB1442466A (en) 1974-03-23 1974-06-10 Method for neutralizing the toxic metabolic products of mould fungi
CY993A CY993A (en) 1974-03-23 1974-06-10 Method for neutralizing the toxic metabloc products of mould fungi
CA202,293A CA1030396A (en) 1974-03-23 1974-06-12 Method for neutralizing the toxic metabolic products of mould fungi
AU70269/74A AU7026974A (en) 1974-03-23 1974-06-20 Method for neutralizing the toxic metabolic products of mouldfungi
FR7421664A FR2264483B1 (en) 1974-03-23 1974-06-21
BE145924A BE816904A (en) 1974-03-23 1974-06-26 PROCESS FOR RENDERING TOXIC METABOLIC MOLD PRODUCTS INOFFENSIVE AND COMPOSITION FOR IMPLEMENTING THE SAID PROCEDURE
TR19642A TR19642A (en) 1974-03-23 1978-06-27 PROCEDURE FOR MAKING THE TOXIC METABOLISM UERUENS OF KUEF MUSHROOMS DAMAGED

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2414146A DE2414146A1 (en) 1974-03-23 1974-03-23 PROCEDURE FOR DETERMINING THE TOXIC METABOLIZER PRODUCTS FROM MOLD

Publications (1)

Publication Number Publication Date
DE2414146A1 true DE2414146A1 (en) 1975-09-25

Family

ID=5910997

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2414146A Pending DE2414146A1 (en) 1974-03-23 1974-03-23 PROCEDURE FOR DETERMINING THE TOXIC METABOLIZER PRODUCTS FROM MOLD

Country Status (23)

Country Link
JP (1) JPS5337419B2 (en)
AT (1) AT349875B (en)
AU (1) AU7026974A (en)
BE (1) BE816904A (en)
CA (1) CA1030396A (en)
CH (1) CH568023A5 (en)
CS (1) CS172882B2 (en)
CY (1) CY993A (en)
DE (1) DE2414146A1 (en)
DK (1) DK195074A (en)
ES (1) ES425401A1 (en)
FI (1) FI129574A (en)
FR (1) FR2264483B1 (en)
GB (1) GB1442466A (en)
HU (1) HU167434B (en)
IT (1) IT1011770B (en)
NL (1) NL7406365A (en)
NO (1) NO741303L (en)
PL (1) PL88731B1 (en)
SE (1) SE414266B (en)
TR (1) TR19642A (en)
YU (1) YU103074A (en)
ZA (1) ZA743678B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2557599C3 (en) * 1975-12-20 1979-09-27 Degesch Gmbh, 6000 Frankfurt Process for rendering the toxic metabolic products of molds harmless
JPS53106623U (en) * 1977-01-31 1978-08-26

Also Published As

Publication number Publication date
TR19642A (en) 1979-09-19
AU7026974A (en) 1976-01-08
CS172882B2 (en) 1977-01-28
ATA291174A (en) 1978-09-15
ZA743678B (en) 1975-06-25
PL88731B1 (en) 1976-09-30
NL7406365A (en) 1975-09-25
ES425401A1 (en) 1976-06-01
NO741303L (en) 1975-09-24
FR2264483B1 (en) 1977-03-11
JPS50125051A (en) 1975-10-01
IT1011770B (en) 1977-02-10
YU103074A (en) 1982-06-30
SE414266B (en) 1980-07-21
CA1030396A (en) 1978-05-02
JPS5337419B2 (en) 1978-10-09
HU167434B (en) 1975-10-28
SE7404642L (en) 1975-09-24
FI129574A (en) 1975-09-24
GB1442466A (en) 1976-07-14
BE816904A (en) 1974-10-16
CY993A (en) 1979-08-02
CH568023A5 (en) 1975-10-31
DK195074A (en) 1975-09-24
AT349875B (en) 1979-04-25
FR2264483A1 (en) 1975-10-17

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