DE2352918A1 - Dihydropyridobenzodiazepine und -benzodiazocine, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel - Google Patents

Dihydropyridobenzodiazepine und -benzodiazocine, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Info

Publication number
DE2352918A1
DE2352918A1 DE19732352918 DE2352918A DE2352918A1 DE 2352918 A1 DE2352918 A1 DE 2352918A1 DE 19732352918 DE19732352918 DE 19732352918 DE 2352918 A DE2352918 A DE 2352918A DE 2352918 A1 DE2352918 A1 DE 2352918A1
Authority
DE
Germany
Prior art keywords
carbon atoms
general formula
alkali metal
radical
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19732352918
Other languages
German (de)
English (en)
Inventor
Ramesh B Petigara
Harry Louis Yale
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of DE2352918A1 publication Critical patent/DE2352918A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/01—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton
    • C07C323/09—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton having sulfur atoms of thio groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/19—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE19732352918 1972-10-24 1973-10-22 Dihydropyridobenzodiazepine und -benzodiazocine, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel Pending DE2352918A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29998672A 1972-10-24 1972-10-24
US00339258A US3825549A (en) 1972-10-24 1973-03-08 Certain dihydropyrido(2,1-b)(1,3)benzodi-azepines and benzodiazocines

Publications (1)

Publication Number Publication Date
DE2352918A1 true DE2352918A1 (de) 1974-05-02

Family

ID=26971513

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19732352918 Pending DE2352918A1 (de) 1972-10-24 1973-10-22 Dihydropyridobenzodiazepine und -benzodiazocine, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2365309*A Pending DE2365309A1 (de) 1972-10-24 1973-10-22 1,2-dihydro-2-iminopyridinderivate, ihre salze, verfahren zu ihrer herstellung und ihre verwendung als bakterizide

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE2365309*A Pending DE2365309A1 (de) 1972-10-24 1973-10-22 1,2-dihydro-2-iminopyridinderivate, ihre salze, verfahren zu ihrer herstellung und ihre verwendung als bakterizide

Country Status (6)

Country Link
US (1) US3825549A (enrdf_load_stackoverflow)
JP (1) JPS4975595A (enrdf_load_stackoverflow)
CA (1) CA1016167A (enrdf_load_stackoverflow)
DE (2) DE2352918A1 (enrdf_load_stackoverflow)
FR (1) FR2203640B1 (enrdf_load_stackoverflow)
GB (1) GB1449861A (enrdf_load_stackoverflow)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE448629B (sv) * 1981-09-24 1987-03-09 Robins Co Inc A H Pyrido/1,4/bensodiazepiner
ZA86171B (en) * 1985-01-16 1986-08-27 Hoffmann La Roche Polycyclic salts
US4990648A (en) * 1988-12-22 1991-02-05 Ici Americas Inc. Process for producing an alkylthiobenzoate
US4925970A (en) * 1988-12-22 1990-05-15 Brown Richard W Process for producing cyclohexadiene thioether

Also Published As

Publication number Publication date
CA1016167A (en) 1977-08-23
FR2203640A1 (enrdf_load_stackoverflow) 1974-05-17
JPS4975595A (enrdf_load_stackoverflow) 1974-07-20
DE2365309A1 (de) 1974-05-30
FR2203640B1 (enrdf_load_stackoverflow) 1978-07-28
GB1449861A (en) 1976-09-15
US3825549A (en) 1974-07-23

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