DE2113438A1 - Anti-microbial nitrofuryl-triazolo -(4,3-b) - pyridazine derivs - used for treating urinary system infections - Google Patents

Anti-microbial nitrofuryl-triazolo -(4,3-b) - pyridazine derivs - used for treating urinary system infections

Info

Publication number
DE2113438A1
DE2113438A1 DE19712113438 DE2113438A DE2113438A1 DE 2113438 A1 DE2113438 A1 DE 2113438A1 DE 19712113438 DE19712113438 DE 19712113438 DE 2113438 A DE2113438 A DE 2113438A DE 2113438 A1 DE2113438 A1 DE 2113438A1
Authority
DE
Grant status
Application
Patent type
Prior art keywords
opt
system
oh
substd
triazolo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19712113438
Other languages
German (de)
Inventor
Herbert Dr Phil Berger
Rudi Dr Phil Gall
Hartmut Dr Rer Nat Merdes
Wolfgang Dr Med Voemel
Winfriede Dr Med Vet Sauer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Abstract

Cpds.: (where X is -O- or -S-; n is 0 or 1; Het is triazolo 4,3-b -pyridazine system and R1 and R2 are 5-7C cycloalkyl or opt. satd. lower hydrocarbyl opt. substd. by OH, SH, alkoxy or alkylmercapto, morpholino, furyl or opt. alkylated amino gps., and R1 and R2 together with N can form an opt. -OH, -COOH or (hydroxy)alkyl gp. - substd. piperidine, piperazine, pyrrolidine or morpholine ring and opt. one of R1 and R2 can be H) and their non-toxic salts, are esp. active against Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and Proteus mirabilis.
DE19712113438 1971-03-19 1971-03-19 Anti-microbial nitrofuryl-triazolo -(4,3-b) - pyridazine derivs - used for treating urinary system infections Pending DE2113438A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19712113438 DE2113438A1 (en) 1971-03-19 1971-03-19 Anti-microbial nitrofuryl-triazolo -(4,3-b) - pyridazine derivs - used for treating urinary system infections

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19712113438 DE2113438A1 (en) 1971-03-19 1971-03-19 Anti-microbial nitrofuryl-triazolo -(4,3-b) - pyridazine derivs - used for treating urinary system infections
GB1160772A GB1324060A (en) 1971-03-19 1972-03-13 Nitrofuryl-triazolo 4,3-b pyridazine derivatives
FR7209373A FR2130372B1 (en) 1971-03-19 1972-03-17

Publications (1)

Publication Number Publication Date
DE2113438A1 true true DE2113438A1 (en) 1972-09-21

Family

ID=5802148

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19712113438 Pending DE2113438A1 (en) 1971-03-19 1971-03-19 Anti-microbial nitrofuryl-triazolo -(4,3-b) - pyridazine derivs - used for treating urinary system infections

Country Status (1)

Country Link
DE (1) DE2113438A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0029103A1 (en) * 1979-11-15 1981-05-27 American Cyanamid Company 6- and 8-Heteroaryl-1,2,4-triazolo(4,3-b)pyridazines
EP0094038A1 (en) * 1982-05-08 1983-11-16 Hoechst Aktiengesellschaft 3-Amino-6-aryl-1,2,4-triazolo(4,3-b)pyridazines, their preparation and use
EP0121490A1 (en) * 1983-03-31 1984-10-10 Hoechst Aktiengesellschaft Substituted 6-aryl-1,2,4-triazolo[4,3-b]pyridazines, their preparation and use
US7173033B2 (en) 2002-03-01 2007-02-06 Astellas Pharma Inc. Nitrogen-containing heterocyclic compound
US8030305B2 (en) 2005-12-21 2011-10-04 Janssen Pharmaceutica N.V. Triazolopyridazines as kinase modulators

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0029103A1 (en) * 1979-11-15 1981-05-27 American Cyanamid Company 6- and 8-Heteroaryl-1,2,4-triazolo(4,3-b)pyridazines
EP0094038A1 (en) * 1982-05-08 1983-11-16 Hoechst Aktiengesellschaft 3-Amino-6-aryl-1,2,4-triazolo(4,3-b)pyridazines, their preparation and use
EP0121490A1 (en) * 1983-03-31 1984-10-10 Hoechst Aktiengesellschaft Substituted 6-aryl-1,2,4-triazolo[4,3-b]pyridazines, their preparation and use
US7173033B2 (en) 2002-03-01 2007-02-06 Astellas Pharma Inc. Nitrogen-containing heterocyclic compound
US8030305B2 (en) 2005-12-21 2011-10-04 Janssen Pharmaceutica N.V. Triazolopyridazines as kinase modulators
US8173654B2 (en) 2005-12-21 2012-05-08 Janssen Pharmaceutica N.V. Triazolopyridazine compounds

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