DE1670848A1 - Verfahren zur Herstellung von Tetrahydroisochinolinen - Google Patents

Verfahren zur Herstellung von Tetrahydroisochinolinen

Info

Publication number
DE1670848A1
DE1670848A1 DE1967F0052134 DEF0052134A DE1670848A1 DE 1670848 A1 DE1670848 A1 DE 1670848A1 DE 1967F0052134 DE1967F0052134 DE 1967F0052134 DE F0052134 A DEF0052134 A DE F0052134A DE 1670848 A1 DE1670848 A1 DE 1670848A1
Authority
DE
Germany
Prior art keywords
tetrahydroisoquinolines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE1967F0052134
Other languages
English (en)
Other versions
DE1670848C3 (de
DE1670848B2 (de
Inventor
Gustav Prof Dipl-Chem Ehrhart
Schmitt Karl Dipl-Chem Dr
Irmgard Dr Hoffmann
Heinrich Ott
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Hoechst AG
Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE1966F0049122 priority Critical patent/DE1670694B2/de
Application filed by Hoechst AG, Farbwerke Hoechst AG filed Critical Hoechst AG
Priority to DE1967F0052135 priority patent/DE1670849C3/de
Priority to DE1967F0052134 priority patent/DE1670848C3/de
Priority claimed from FR105303A external-priority patent/FR1524487A/fr
Publication of DE1670848A1 publication Critical patent/DE1670848A1/de
Publication of DE1670848B2 publication Critical patent/DE1670848B2/de
Application granted granted Critical
Publication of DE1670848C3 publication Critical patent/DE1670848C3/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
DE1967F0052134 1966-05-05 1967-04-15 Expired DE1670848C3 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE1966F0049122 DE1670694B2 (de) 1966-05-05 1966-05-05 Verfahren zur herstellung von tetrahydroisochinolinen
DE1967F0052135 DE1670849C3 (de) 1966-05-05 1967-04-15
DE1967F0052134 DE1670848C3 (de) 1966-05-05 1967-04-15

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
DE1966F0049122 DE1670694B2 (de) 1966-05-05 1966-05-05 Verfahren zur herstellung von tetrahydroisochinolinen
DE1967F0052135 DE1670849C3 (de) 1966-05-05 1967-04-15
DE1967F0052134 DE1670848C3 (de) 1966-05-05 1967-04-15
AT06072/69A AT282634B (de) 1966-05-05 1967-05-03 Verfahren zur herstellung von neuen tetrahydroisochinolinen und von deren salzen
AT607169A AT289804B (de) 1966-05-05 1967-05-03 Verfahren zur Herstellung von neuen Tetrahydroisochinolinen und von deren Salzen
SE626567A SE330170B (de) 1966-05-05 1967-05-03
NO16798067A NO121721B (de) 1966-05-05 1967-05-03
AT413967A AT281827B (de) 1966-05-05 1967-05-03 Verfahren zur Herstellung von neuen Tetrahydroisochinolinen und von deren Salzen
DK236067A DK123598B (da) 1966-05-05 1967-05-03 Analogifremgangsmåde til fremstilling af tetrahydroisoquinoliner.
CH225370A CH501628A (de) 1966-05-05 1967-05-05 Verfahren zur Herstellung von Tetrahydroisochinolinen
GB2101667A GB1164192A (en) 1966-05-05 1967-05-05 Tetrahydroisoquinolines and process for preparing them
FR105303A FR1524487A (fr) 1966-05-05 1967-05-05 Tétrahydro-isoquinoléines et leur préparation
CH225270A CH487893A (de) 1966-05-05 1967-05-05 Verfahren zur Herstellung von Tetrahydroisochinolinen
CH641467A CH487892A (de) 1966-05-05 1967-05-05 Verfahren zur Herstellung von Tetrahydroisochinolinen
NL6706322A NL157899B (nl) 1966-05-05 1967-05-05 PROCEDURE FOR PREPARING A MEDICINAL PRODUCT, AN FORMED MEDICINAL PRODUCT THEREFORE OBTAINED AND PROCESS FOR PREPARING A 4-PHENYL-1,2,3,4-TETRAHYDRO-ISOCHINOLINE DERIVATIVE.
BE698033D BE698033A (de) 1966-05-05 1967-05-05
FR6496D FR6496M (de) 1966-05-05 1967-08-04
FR6646D FR6646M (de) 1966-05-05 1967-08-04
US86793269 US3577424A (en) 1966-05-05 1969-10-20 4-phenyl-8-amino tetrahydroisoquinolines

Publications (3)

Publication Number Publication Date
DE1670848A1 true DE1670848A1 (de) 1971-04-08
DE1670848B2 DE1670848B2 (de) 1979-10-11
DE1670848C3 DE1670848C3 (de) 1980-06-19

Family

ID=27210480

Family Applications (3)

Application Number Title Priority Date Filing Date
DE1966F0049122 Granted DE1670694B2 (de) 1966-05-05 1966-05-05 Verfahren zur herstellung von tetrahydroisochinolinen
DE1967F0052135 Expired DE1670849C3 (de) 1966-05-05 1967-04-15
DE1967F0052134 Expired DE1670848C3 (de) 1966-05-05 1967-04-15

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE1966F0049122 Granted DE1670694B2 (de) 1966-05-05 1966-05-05 Verfahren zur herstellung von tetrahydroisochinolinen
DE1967F0052135 Expired DE1670849C3 (de) 1966-05-05 1967-04-15

Country Status (11)

Country Link
US (1) US3577424A (de)
AT (3) AT289804B (de)
BE (1) BE698033A (de)
CH (3) CH487893A (de)
DE (3) DE1670694B2 (de)
DK (1) DK123598B (de)
FR (2) FR6496M (de)
GB (1) GB1164192A (de)
NL (1) NL157899B (de)
NO (1) NO121721B (de)
SE (1) SE330170B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4048180A (en) * 1968-03-18 1977-09-13 Imperial Chemical Industries Limited Pyridyl-tetrahydropyrans and process for preparing same
US3947456A (en) * 1970-01-06 1976-03-30 Hoffman-La Roche Inc. Substituted 4-phenyl isoquinolines
US3666763A (en) * 1970-01-06 1972-05-30 Hoffmann La Roche 4-phenyl isoquinolines and process for preparing same
CH538477A (de) * 1970-01-06 1973-06-30 Hoffmann La Roche Verfahren zur Herstellung von Isochinolin-Derivaten
FR2081572B1 (de) * 1970-03-12 1973-04-06 Rhone Poulenc Sa
US4419517A (en) * 1973-06-01 1983-12-06 E. I. Du Pont De Nemours & Co. 4a-Aryl-trans-decahydroisoquinolines
IL45823A (en) * 1973-10-20 1977-10-31 Hoechst Ag Substituted 1-phenyl-4-alkyl(dialkyl or cyclic) aminoalkyl-1,4-dihydro-2h-isoquinoline-3-one derivatives
SE7509022L (sv) 1974-09-09 1976-03-10 Du Pont ASSOCIATIONS WITH ANALGETIC EFFECT
DE2723524C2 (de) * 1977-05-25 1987-08-20 Hoechst Ag, 6230 Frankfurt, De
DE2724610A1 (de) * 1977-06-01 1978-12-14 Hoechst Ag 4-phenyl-8-amino-tetrahydroisochinoline
DE2724683A1 (de) * 1977-06-01 1978-12-14 Hoechst Ag Antidepressiv wirksame pharmazeutische praeparate
US4340600A (en) * 1980-05-22 1982-07-20 Smithkline Corporation Renal dilating methods and compositions using 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines
US4477670A (en) * 1981-02-19 1984-10-16 Hoechst-Roussel Pharmaceuticals Inc. 4-Aryloxy-1,2,3,4-tetrahydroisoquinolines
US4375471A (en) * 1981-02-19 1983-03-01 Hoechst-Roussel Pharmaceuticals Inc. 4-Aryloxy-1,2,3,4-tetrahydroisoquinolines
BG33347A1 (en) * 1981-06-10 1983-02-15 Zabunova Cvetanova Method for obtaining of n- (2- aminobenzyl)- 1- phenyl- 2- methylaminoethanol
HU186518B (en) * 1982-06-04 1985-08-28 Egyt Gyogyszervegyeszeti Gyar Process for producing 8-bracket-amino-acyl-amino-bracket closed-4-aryl-2-methyl-1,2,3,4-tetrahydro-isoquinoline derivatives
DE3333994A1 (de) * 1983-09-21 1985-04-04 Troponwerke Gmbh & Co Kg Neue pyridoindolderivate, verfahren zu ihrer herstellung und ihre verwendung
BG39661A1 (en) * 1984-04-13 1986-08-29 Ivanova Antiulcer means
GB8509834D0 (en) * 1985-04-17 1985-05-22 Beecham Group Plc Compounds
US4876261A (en) * 1987-03-27 1989-10-24 Akihiro Tanaka Substituted tetrahydroisoquinoline compounds and composition containing them
GB9816984D0 (en) * 1998-08-05 1998-09-30 Smithkline Beecham Plc Novel compounds
GB9817424D0 (en) 1998-08-11 1998-10-07 Smithkline Beecham Plc Novel compounds
MXPA05011225A (es) * 2003-04-18 2005-12-14 Pharmacia & Upjohn Co Llc POLYTHERAPIES
WO2009111031A2 (en) * 2008-03-04 2009-09-11 Intra-Cellular Therapies, Inc. Methods of treating vasomotor symptoms

Also Published As

Publication number Publication date
AT282634B (de) 1970-07-10
SE330170B (de) 1970-11-09
DE1670849B2 (de) 1977-12-01
DE1670694B2 (de) 1976-07-22
AT289804B (de) 1971-05-10
CH501628A (de) 1971-01-15
NL6706322A (de) 1967-11-06
DE1670849A1 (de) 1971-02-25
CH487892A (de) 1970-03-31
AT281827B (de) 1970-06-10
DE1670849C3 (de) 1978-07-20
DK123598B (da) 1972-07-10
FR6646M (de) 1969-01-20
GB1164192A (en) 1969-09-17
CH487893A (de) 1970-03-31
FR6496M (de) 1968-11-25
DE1670848B2 (de) 1979-10-11
BE698033A (de) 1967-11-06
DE1670848C3 (de) 1980-06-19
DE1670694A1 (de) 1970-12-03
NL157899B (nl) 1978-09-15
NO121721B (de) 1971-04-05
US3577424A (en) 1971-05-04

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Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)