DE1617363B1 - Verfahren zur Herstellung hochaktiver Enzym-Verdauungspraeparate - Google Patents

Verfahren zur Herstellung hochaktiver Enzym-Verdauungspraeparate

Info

Publication number
DE1617363B1
DE1617363B1 DE1967B0095714 DEB0095714A DE1617363B1 DE 1617363 B1 DE1617363 B1 DE 1617363B1 DE 1967B0095714 DE1967B0095714 DE 1967B0095714 DE B0095714 A DEB0095714 A DE B0095714A DE 1617363 B1 DE1617363 B1 DE 1617363B1
Authority
DE
Germany
Prior art keywords
preparations
enzymes
active
digestive
small intestine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE1967B0095714
Other languages
German (de)
English (en)
Inventor
Peter Dr Rer Nat Rieckmann
Werner Dr Rer Nat Rothe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Priority to DE1967B0095714 priority Critical patent/DE1617363B1/de
Priority to BE724945D priority patent/BE724945A/xx
Priority to NL6817564A priority patent/NL6817564A/xx
Publication of DE1617363B1 publication Critical patent/DE1617363B1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE1967B0095714 1967-12-06 1967-12-06 Verfahren zur Herstellung hochaktiver Enzym-Verdauungspraeparate Pending DE1617363B1 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE1967B0095714 DE1617363B1 (de) 1967-12-06 1967-12-06 Verfahren zur Herstellung hochaktiver Enzym-Verdauungspraeparate
BE724945D BE724945A (https=) 1967-12-06 1968-12-05
NL6817564A NL6817564A (https=) 1967-12-06 1968-12-06

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE1967B0095714 DE1617363B1 (de) 1967-12-06 1967-12-06 Verfahren zur Herstellung hochaktiver Enzym-Verdauungspraeparate

Publications (1)

Publication Number Publication Date
DE1617363B1 true DE1617363B1 (de) 1972-05-31

Family

ID=6988295

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1967B0095714 Pending DE1617363B1 (de) 1967-12-06 1967-12-06 Verfahren zur Herstellung hochaktiver Enzym-Verdauungspraeparate

Country Status (3)

Country Link
BE (1) BE724945A (https=)
DE (1) DE1617363B1 (https=)
NL (1) NL6817564A (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0021129A3 (en) * 1979-06-08 1981-11-11 Kali-Chemie Pharma Gmbh Pancreatin pellets, process for their manufacture and medicines containing these pellets
EP0283442A1 (en) * 1987-01-21 1988-09-21 Sandoz S.A. Process for the manufacture of gastro-resistant and enterosoluble small spheres of digestive enzyme and pharmaceutical preparation so obtained
DK154610B (da) * 1975-06-10 1988-12-05 Johnson & Johnson Fremgangsmaade til fremstilling af et fordoejelsesenzympraeparat

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1598458A (en) * 1977-04-01 1981-09-23 Hoechst Uk Ltd Tableting of microcapsules

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154610B (da) * 1975-06-10 1988-12-05 Johnson & Johnson Fremgangsmaade til fremstilling af et fordoejelsesenzympraeparat
EP0021129A3 (en) * 1979-06-08 1981-11-11 Kali-Chemie Pharma Gmbh Pancreatin pellets, process for their manufacture and medicines containing these pellets
DE2923279C2 (de) * 1979-06-08 1987-07-09 Kali-Chemie Pharma Gmbh, 3000 Hannover Verfahren zur Herstellung von Pankreatin-Pellets und diese enthaltende Arzneimittel
EP0283442A1 (en) * 1987-01-21 1988-09-21 Sandoz S.A. Process for the manufacture of gastro-resistant and enterosoluble small spheres of digestive enzyme and pharmaceutical preparation so obtained

Also Published As

Publication number Publication date
BE724945A (https=) 1969-06-05
NL6817564A (https=) 1969-06-10

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