DE122004000048I1 - Neue chinuclidin-derivate und diese enthaltende pharmazeutische Pr{parate. - Google Patents
Neue chinuclidin-derivate und diese enthaltende pharmazeutische Pr{parate.Info
- Publication number
- DE122004000048I1 DE122004000048I1 DE200412000048 DE122004000048C DE122004000048I1 DE 122004000048 I1 DE122004000048 I1 DE 122004000048I1 DE 200412000048 DE200412000048 DE 200412000048 DE 122004000048 C DE122004000048 C DE 122004000048C DE 122004000048 I1 DE122004000048 I1 DE 122004000048I1
- Authority
- DE
- Germany
- Prior art keywords
- new
- pharmaceutical preparations
- preparations containing
- diseases
- chinuclidine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
- C07D221/12—Phenanthridines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K19/00—Liquid crystal materials
- C09K19/04—Liquid crystal materials characterised by the chemical structure of the liquid crystal components, e.g. by a specific unit
- C09K19/06—Non-steroidal liquid crystal compounds
- C09K19/34—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring
- C09K19/3441—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom
- C09K19/3444—Non-steroidal liquid crystal compounds containing at least one heterocyclic ring having nitrogen as hetero atom the heterocyclic ring being a six-membered aromatic ring containing one nitrogen atom, e.g. pyridine
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Materials Engineering (AREA)
- Urology & Nephrology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Tea And Coffee (AREA)
- External Artificial Organs (AREA)
- Liquid Crystal Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP32704594 | 1994-12-28 | ||
PCT/JP1995/002713 WO1996020194A1 (fr) | 1994-12-28 | 1995-12-27 | Nouveaux derives de quinuclidine et composition pharmaceutique les contenant |
Publications (2)
Publication Number | Publication Date |
---|---|
DE122004000048I1 true DE122004000048I1 (de) | 2005-04-21 |
DE122004000048I2 DE122004000048I2 (de) | 2006-02-02 |
Family
ID=18194699
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE200412000048 Active DE122004000048I2 (de) | 1994-12-28 | 1995-12-27 | Neue Chinuclidin-Derivate und diese enthaltende pharmazeutische Pr{parate |
DE69529844T Expired - Lifetime DE69529844T2 (de) | 1994-12-28 | 1995-12-27 | Neue chinuclidin-derivate und diese enthaltende pharmazeutische präparate |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69529844T Expired - Lifetime DE69529844T2 (de) | 1994-12-28 | 1995-12-27 | Neue chinuclidin-derivate und diese enthaltende pharmazeutische präparate |
Country Status (24)
Country | Link |
---|---|
US (2) | US6017927A (de) |
EP (1) | EP0801067B1 (de) |
JP (1) | JP3014457B2 (de) |
KR (1) | KR100386487B1 (de) |
CN (1) | CN1045601C (de) |
AT (1) | ATE233761T1 (de) |
AU (1) | AU695616B2 (de) |
CA (1) | CA2208839C (de) |
DE (2) | DE122004000048I2 (de) |
DK (1) | DK0801067T3 (de) |
ES (1) | ES2193208T3 (de) |
FI (1) | FI115631B (de) |
FR (1) | FR04C0032I2 (de) |
HU (1) | HU223778B1 (de) |
LU (1) | LU91133I9 (de) |
MX (1) | MX9704880A (de) |
NL (1) | NL300141I2 (de) |
NO (4) | NO2005012I1 (de) |
NZ (1) | NZ298144A (de) |
PL (1) | PL182344B1 (de) |
PT (1) | PT801067E (de) |
RU (1) | RU2143432C1 (de) |
TW (1) | TW305842B (de) |
WO (1) | WO1996020194A1 (de) |
Families Citing this family (99)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100137358A1 (en) * | 1996-11-05 | 2010-06-03 | Dr. Reddy's Laboratories Ltd. | Solifenacin compositions |
FR2772378B1 (fr) * | 1997-12-12 | 2000-02-04 | Synthelabo | Derives d'imidazole, leur preparation et leur application en therapeutique |
ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
US7214687B2 (en) | 1999-07-14 | 2007-05-08 | Almirall Ag | Quinuclidine derivatives and medicinal compositions containing the same |
JP2001316670A (ja) * | 2000-05-02 | 2001-11-16 | Dainippon Ink & Chem Inc | 液晶組成物 |
DK1300407T4 (da) | 2000-06-27 | 2011-09-05 | S A L V A T Lab Sa | Carbamater afledt af arylalkylaminer |
BR0116450A (pt) | 2000-12-22 | 2003-09-30 | Almirall Prodesfarma Ag | Composto, processos para a preparação de um carbamato, e para produzir um sal, composição farmacêutica, uso de um composto ou de uma composição farmacêutica, e, produto de combinação |
PL363807A1 (en) | 2000-12-28 | 2004-11-29 | Almirall Prodesfarma Ag | Novel quinuclidine derivatives and medicinal compositions containing the same |
PT1405638E (pt) * | 2001-07-10 | 2011-04-06 | Astellas Pharma Inc | Composição farmacêutica compreendendo 1-fenil-1,2,3,4 tetrahidroisoquinolino- 2-carboxilato de quinuclidin-3'-ilo para tratamento de cistite intersticial e/ou prostatite não bacteriana |
ES2425347T3 (es) | 2001-12-20 | 2013-10-14 | Chiesi Farmaceutici S.P.A. | Derivados de carbamato de 1-alquil-1-azoniabiciclo[2.2.2]octano y su uso como antagonistas de receptores muscarínicos |
US20060035923A1 (en) * | 2002-06-07 | 2006-02-16 | Rian Van Meeteren | Overactive bladder treating drug |
ES2203327B1 (es) | 2002-06-21 | 2005-06-16 | Almirall Prodesfarma, S.A. | Nuevos carbamatos de quinuclidina y composiciones farmaceuticas que los contienen. |
ES2204295B1 (es) | 2002-07-02 | 2005-08-01 | Almirall Prodesfarma, S.A. | Nuevos derivados de quinuclidina-amida. |
BR0215801A (pt) | 2002-07-08 | 2005-05-10 | Ranbaxy Lab Ltd | Derivados de 3,6-dissubstituìdos azabiciclo [3.1.0] hexano úteis como antagonistas de receptores muscarìnicos |
EP1546098B1 (de) | 2002-07-31 | 2008-05-28 | Ranbaxy Laboratories Limited | 3,6-disubstituierte azabicyclo [3.1.0]hexanderivate, die sich als muscarinrezeptorantagonisten eignen |
US7410993B2 (en) | 2002-08-09 | 2008-08-12 | Ranbaxy Laboratories Limited | 3,6-disubstituted azabicyclo [3.1.0] hexane deriviatives useful as muscarinic receptor antagonists |
WO2004018422A1 (en) | 2002-08-23 | 2004-03-04 | Ranbaxy Laboratories Limited | Fluoro and sulphonylamino containing 3,6-disubstituted azabicyclo (3.1.0) hexane derivatives as muscarinic receptor antagonists |
BR0315784A (pt) * | 2002-10-29 | 2005-09-20 | Pharmacia & Upjohn Co Llc | Compostos de amÈnio quaternário |
EP1572648B1 (de) | 2002-12-10 | 2008-07-09 | Ranbaxy Laboratories, Ltd. | 3,6-disubstituierte azabicyclo ¬3.1.0 -hexanderivative als antagonisten des muscarinrezeptors |
US20040142034A1 (en) * | 2002-12-20 | 2004-07-22 | Dynogen Pharmaceuticals, Inc. | Methods of treating non-painful bladder disorders using alpha2delta subunit calcium channel modulators |
AU2002347552A1 (en) | 2002-12-23 | 2004-07-14 | Ranbaxy Laboratories Limited | 1-substituted-3-pyrrolidine derivatives as muscarinic receptor antagonists |
WO2004056811A1 (en) * | 2002-12-23 | 2004-07-08 | Ranbaxy Laboratories Limited | Flavaxate derivatives as muscarinic receptor antagonists |
US7488748B2 (en) | 2003-01-28 | 2009-02-10 | Ranbaxy Laboratories Limited | 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
DK1492519T3 (da) * | 2003-03-21 | 2007-03-05 | Dynogen Pharmaceuticals Inc | Fremgangsmåder til behandling af lidelser i den nedre urinvej ved anvendelse af alfa-2-delta-underenhedscalciumkanalsmodulatorer med glat muskel-modulatorer |
US7517905B2 (en) | 2003-04-09 | 2009-04-14 | Ranbaxy Laboratories Limited | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
JP2006514978A (ja) | 2003-04-10 | 2006-05-18 | ランバクシー ラボラトリーズ リミテッド | ムスカリン受容体アンタゴニストである置換アザビシクロヘキサン誘導体 |
EP1615887A1 (de) | 2003-04-10 | 2006-01-18 | Ranbaxy Laboratories, Ltd. | 3, 6-disubstitutierte azabicyclohexanderivate als muscarinrezeptorantagonisten |
EA009387B1 (ru) | 2003-04-11 | 2007-12-28 | Рэнбакси Лабораториз Лимитед | Азабициклические производные в качестве антагонистов мускаринового рецептора |
WO2004091597A2 (en) * | 2003-04-15 | 2004-10-28 | Pharmacia & Upjohn Company Llc | Method of treating irritable bowel syndrome (ibs) |
US20050175689A1 (en) * | 2003-10-27 | 2005-08-11 | Yamanouchi Pharmaceutical Co., Ltd. | Coated fine particles containing drug for intrabuccally fast disintegrating tablet |
JPWO2005075474A1 (ja) * | 2004-02-09 | 2007-10-11 | アステラス製薬株式会社 | コハク酸ソリフェナシン含有組成物 |
WO2005077364A1 (ja) * | 2004-02-18 | 2005-08-25 | Yamanouchi Pharmaceutical Co., Ltd. | ソリフェナシンの経皮投与製剤およびその経皮透過改善方法 |
JPWO2005087231A1 (ja) * | 2004-03-16 | 2008-01-24 | アステラス製薬株式会社 | ソリフェナシン含有組成物 |
EP1726304A4 (de) * | 2004-03-16 | 2010-04-28 | Astellas Pharma Inc | Solifenacin enthaltende zusammensetzung |
MXPA06010908A (es) * | 2004-03-25 | 2006-12-15 | Astellas Pharma Inc | Composicion para la preparacion farmaceutica solida de solifenacina o una sal de la misma. |
ZA200608614B (en) * | 2004-03-25 | 2008-06-25 | Astellas Pharma Inc | Composition for solid pharmaceutical preparation of solifenacin or salt thereof |
WO2006035280A1 (en) * | 2004-09-27 | 2006-04-06 | Ranbaxy Laboratories Limited | 3,4-dihydroisoquinoline compounds as muscrinic receptor antagonists for the treatment of respiratory, urinary and gastrointestinal diseases |
WO2006035303A1 (en) * | 2004-09-29 | 2006-04-06 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
WO2006070735A1 (ja) * | 2004-12-27 | 2006-07-06 | Astellas Pharma Inc. | ソリフェナシンまたはその塩の安定な粒子状医薬組成物 |
RU2397767C2 (ru) * | 2004-12-27 | 2010-08-27 | Астеллас Фарма Инк. | Стабильная, состоящая из частиц фармацевтическая композиция, содержащая солифенацин или его соль |
CA2599158C (en) * | 2005-02-25 | 2011-01-25 | Astellas Pharma Inc. | Pharmaceutical agent comprising solifenacin |
JP3701964B1 (ja) | 2005-03-08 | 2005-10-05 | アステラス製薬株式会社 | キヌクリジン誘導体の新規な塩 |
US20080255188A1 (en) * | 2005-07-11 | 2008-10-16 | Naresh Kumar | Muscarinic Receptor Antagonists |
US7815939B2 (en) | 2005-07-20 | 2010-10-19 | Astellas Pharma Inc. | Coated fine particles containing drug for intrabuccally fast disintegrating dosage forms |
BRPI0617674A2 (pt) | 2005-10-19 | 2011-08-02 | Ranbaxy Lab Ltd | composições farmacêuticas e seus usos |
US20070173528A1 (en) * | 2005-12-21 | 2007-07-26 | Nurit Perlman | Process for preparing solifenacin |
CZ300699B6 (cs) * | 2006-06-21 | 2009-07-22 | Zentiva, A. S. | Zpusob prípravy solifenacinu |
US20090326230A1 (en) * | 2006-07-19 | 2009-12-31 | Dr. Reddy's Laboratories Ltd. | Process for preparing solifenacin and its salts |
ES2298049B1 (es) * | 2006-07-21 | 2009-10-20 | Laboratorios Almirall S.A. | Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano. |
US20080114028A1 (en) * | 2006-07-24 | 2008-05-15 | Tamas Koltai | Process for preparing polymorphic forms of solifenacin succinate |
EP1922308A2 (de) * | 2006-08-03 | 2008-05-21 | Teva Pharmaceutical Industries Ltd. | Verfahren zur optischen trennung von 1-phenyl-1,2,3,4- tetrahydroisochinolinen |
TW200825084A (en) * | 2006-11-14 | 2008-06-16 | Astrazeneca Ab | New compounds 521 |
US20100029944A1 (en) * | 2006-11-22 | 2010-02-04 | Corporacion Medichem, S.L. | Process for the Synthesis of Solifenacin |
CZ300692B6 (cs) * | 2006-12-22 | 2009-07-15 | Zentiva, A. S. | Zpusob prípravy solifenacinu |
EP2142540A2 (de) * | 2007-03-30 | 2010-01-13 | Medichem S.A. | Verbessertes verfahren zur synthese von solifenacin |
EP2146693A2 (de) * | 2007-04-11 | 2010-01-27 | Dr. Reddy's Laboratories Ltd. | Solifenacin-zusammensetzungen |
WO2009011844A1 (en) * | 2007-07-13 | 2009-01-22 | Teva Pharmaceutical Industries Ltd. | Processes for solifenacin preparation |
JPWO2009013846A1 (ja) * | 2007-07-20 | 2010-10-07 | アステラス製薬株式会社 | 前立腺肥大に伴う下部尿路症状の改善用医薬組成物 |
EP2018850A1 (de) * | 2007-07-24 | 2009-01-28 | Ratiopharm GmbH | Pharmazeutische Zusammensetzung mit Solifenacin oder einem pharmazeutisch akzeptablen Salz daraus |
SI2216021T1 (sl) * | 2007-11-02 | 2013-01-31 | Astellas Pharma Inc. | Farmacevtski sestavek za zdravljenje prekomerno aktivnega sečnega mehurja |
US8476297B2 (en) | 2007-12-04 | 2013-07-02 | Amgen Inc. | TRP-M8 receptor ligands and their use in treatments |
EP2489666A3 (de) * | 2007-12-04 | 2012-12-26 | Cadila Healthcare Limited | Chemisch und chiral reine Solifenacinbase und deren Salze |
ITMI20080195A1 (it) | 2008-02-08 | 2009-08-09 | Dipharma Francis Srl | Procedimento per la preparazione di solifenacin |
EP2100599A1 (de) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung |
EP2100598A1 (de) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung |
EP3178477A1 (de) | 2008-03-27 | 2017-06-14 | Chase Pharmaceuticals Corporation | Kombination von nspacha (periphärem anticholinergen wirkstoff) wie solifenacin und einem achei (acetylcholinesterase inhibitor) wie donepezil in der verwendung zur behandlung von demenz |
PL385264A1 (pl) | 2008-05-23 | 2009-12-07 | Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna | Sposób wytwarzania enancjomerycznie czystej (S)-1-fenylo-1, 2, 3, 4-tetrahydroizochinoliny |
PL385265A1 (pl) * | 2008-05-23 | 2009-12-07 | Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna | Sposób wytwarzania solifenacyny i/lub jej soli o wysokiej czystości farmaceutycznej |
EP3067353B1 (de) | 2008-07-29 | 2017-11-22 | KRKA, D.D., Novo Mesto | Verfahren zur herstellung von solifenacinsalzen und einbau davon in pharmazeutischen darreichungsformen |
EP2181707A1 (de) | 2008-11-04 | 2010-05-05 | Astellas Ireland Co., Ltd. | Kombinierte Verwendung eines alpha-adrenergischen Rezeptorantagonisten und eines Antimuskarinmittels |
LT2394648T (lt) | 2009-02-04 | 2016-10-10 | Astellas Pharma Inc. | Farmacinė kompozicija vartojimui per burną |
PL2406257T3 (pl) | 2009-03-09 | 2020-01-31 | Megafine Pharma (P) Ltd. | Nowy sposób wytwarzania solifenacyny i jej nowy produkt pośredni |
WO2010113840A1 (ja) | 2009-03-30 | 2010-10-07 | アステラス製薬株式会社 | ソリフェナシン非晶質体を含有した固形医薬組成物 |
WO2011048607A1 (en) | 2009-09-25 | 2011-04-28 | Cadila Healthcare Limited | Processes for the preparation of solifenacin or a salt thereof |
PL234208B1 (pl) | 2010-01-18 | 2020-01-31 | Zakl Farmaceutyczne Polpharma Spolka Akcyjna | Sposób wytwarzania bursztynianu solifenacyny |
WO2011125763A1 (ja) | 2010-03-31 | 2011-10-13 | 小野薬品工業株式会社 | 手足症候群の予防および/または治療剤 |
CA2796877A1 (en) | 2010-04-30 | 2011-11-03 | Merck Sharp & Dohme Corp. | Novel beta 3 adrenergic receptor agonists |
HUE029400T2 (en) | 2010-05-19 | 2017-03-28 | Astellas Pharma Inc | Pharmaceutical composition containing Solifenacin |
WO2012001481A1 (en) | 2010-06-28 | 2012-01-05 | Aurobindo Pharma Limited | Novel process for the preparation of solifenacin succinate |
JP5826262B2 (ja) | 2010-07-05 | 2015-12-02 | クリスタル ファーマ,エセ.ア.ウ. | ソリフェナシン塩 |
EP2638039A1 (de) | 2010-11-11 | 2013-09-18 | Hexal AG | Kristallines solifenacin-succinat |
EP2510928A1 (de) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium zur Verbesserung der Schlafqualität bei atemwegserkrankten Patienten |
EP2706997B1 (de) | 2011-05-10 | 2019-03-27 | TheraVida, Inc. | Kombinationen aus solifenacin und pilocarpin zur behandlung von hyperaktiver blase |
US20140228575A1 (en) | 2011-06-22 | 2014-08-14 | Isochem | Process for the Preparation of Solifenacin and Salts Thereof |
KR101365849B1 (ko) | 2012-03-28 | 2014-02-24 | 경동제약 주식회사 | 솔리페나신 또는 그의 염의 제조방법 및 이에 사용되는 신규 중간체 |
JP2015521635A (ja) * | 2012-07-02 | 2015-07-30 | ファーマシェン エス.エー. | ソリフェナシン又はその塩の調製方法 |
CA2883270A1 (en) | 2012-08-31 | 2014-03-06 | Astellas Pharma Inc. | Orally administered medical composition |
EP2892514A4 (de) | 2012-09-05 | 2016-04-13 | Chase Pharmaceuticals Corp | Neuroprotektive anticholinergische zusammensetzung und verfahren |
CN103787969B (zh) | 2012-10-30 | 2016-07-06 | 上海京新生物医药有限公司 | 一种(1s)-1-苯基-3,4-二氢-2(1h)-异喹啉甲酸酯的制备方法 |
CN104854105B (zh) * | 2012-12-06 | 2017-05-17 | 奇斯药制品公司 | 具有毒蕈碱受体拮抗剂和β2肾上腺素能受体激动剂活性的化合物 |
EP2778167A1 (de) | 2013-03-11 | 2014-09-17 | Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi | Stabile pharmazeutische Zubereitung enthaltend Solifenacin oder deren pharmazeutisch verträgliches Salz |
US9751875B2 (en) * | 2013-07-13 | 2017-09-05 | Beijing Fswelcome Technology Development Co., Ltd. | Quinine compounds, and optical isomers, preparation method and medical use thereof |
CA3193201A1 (en) | 2014-05-06 | 2015-11-12 | Anthony G. Visco | Methods of treating or preventing preterm labor |
CN104592221A (zh) * | 2015-01-26 | 2015-05-06 | 中山奕安泰医药科技有限公司 | 一种合成索非那新的工艺 |
KR20160146428A (ko) | 2015-06-12 | 2016-12-21 | 한미정밀화학주식회사 | 솔리페나신 또는 그의 약학적으로 허용되는 염과 락토즈를 포함하는 안정한 무정형 솔리페나신 약학 조성물 및 그의 제조방법 |
KR102148414B1 (ko) | 2017-05-15 | 2020-08-26 | 주식회사 서울제약 | 솔리페나신을 유효성분으로 하는 구강붕해필름 |
TW201927783A (zh) | 2017-12-12 | 2019-07-16 | 美商阿爾庫達醫療公司 | 顆粒體蛋白前體調節劑及其使用方法 |
EP3983401A1 (de) * | 2019-06-12 | 2022-04-20 | Arkuda Therapeutics | Progranulin-modulatoren und verfahren zu deren verwendung |
CN113200979A (zh) * | 2021-04-13 | 2021-08-03 | 上海予君生物科技发展有限公司 | 一种琥珀酸索非那新的合成工艺 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0247266B1 (de) * | 1986-01-07 | 1993-03-10 | Beecham Group Plc | Indolderivate mit einer azabicyclischen Seitenkette, Verfahren zu ihrer Herstellung, Zwischenprodukte und pharmazeutische Zusammensetzungen |
IT1231238B (it) * | 1987-09-21 | 1991-11-26 | Angeli Inst Spa | Derivati ammidinici |
GB9023023D0 (en) * | 1990-10-23 | 1990-12-05 | Barlow Richard B | Pharmaceutical compositions |
GB9202443D0 (en) * | 1992-02-05 | 1992-03-18 | Fujisawa Pharmaceutical Co | A novel substituted-acetamide compound and a process for the preparation thereof |
JPH076635A (ja) * | 1993-06-18 | 1995-01-10 | Sony Corp | 信号伝送ケーブル |
AU7545894A (en) * | 1993-09-02 | 1995-03-22 | Yamanouchi Pharmaceutical Co., Ltd. | Carbamate derivative and medicine containing the same |
JPH07258250A (ja) * | 1994-03-25 | 1995-10-09 | Yamanouchi Pharmaceut Co Ltd | エステル誘導体 |
EP1424021B1 (de) * | 2002-11-27 | 2006-09-13 | Selmac S.r.l. | Vorrichtung zum Positionieren und Spannen geformter Teile und damit ausgerüstete Maschine |
-
1988
- 1988-09-19 NO NO2005012C patent/NO2005012I1/no unknown
-
1995
- 1995-12-27 TW TW084113934A patent/TW305842B/zh not_active IP Right Cessation
- 1995-12-27 NZ NZ298144A patent/NZ298144A/en not_active IP Right Cessation
- 1995-12-27 CN CN95197088A patent/CN1045601C/zh not_active Expired - Lifetime
- 1995-12-27 DE DE200412000048 patent/DE122004000048I2/de active Active
- 1995-12-27 PL PL95321019A patent/PL182344B1/pl unknown
- 1995-12-27 NL NL300141C patent/NL300141I2/nl unknown
- 1995-12-27 PT PT95942276T patent/PT801067E/pt unknown
- 1995-12-27 WO PCT/JP1995/002713 patent/WO1996020194A1/ja active IP Right Grant
- 1995-12-27 US US08/860,377 patent/US6017927A/en not_active Expired - Lifetime
- 1995-12-27 MX MX9704880A patent/MX9704880A/es unknown
- 1995-12-27 DE DE69529844T patent/DE69529844T2/de not_active Expired - Lifetime
- 1995-12-27 RU RU97112907/04A patent/RU2143432C1/ru active Protection Beyond IP Right Term
- 1995-12-27 HU HU9701895A patent/HU223778B1/hu active Protection Beyond IP Right Term
- 1995-12-27 EP EP95942276A patent/EP0801067B1/de not_active Expired - Lifetime
- 1995-12-27 DK DK95942276T patent/DK0801067T3/da active
- 1995-12-27 KR KR1019970703649A patent/KR100386487B1/ko not_active IP Right Cessation
- 1995-12-27 ES ES95942276T patent/ES2193208T3/es not_active Expired - Lifetime
- 1995-12-27 AT AT95942276T patent/ATE233761T1/de active
- 1995-12-27 CA CA002208839A patent/CA2208839C/en not_active Expired - Lifetime
- 1995-12-27 JP JP8520367A patent/JP3014457B2/ja not_active Expired - Lifetime
- 1995-12-27 AU AU43553/96A patent/AU695616B2/en not_active Expired
-
1997
- 1997-06-27 NO NO19973027A patent/NO318026B1/no not_active IP Right Cessation
- 1997-06-27 FI FI972775A patent/FI115631B/fi active Protection Beyond IP Right Term
-
1999
- 1999-05-14 US US09/312,392 patent/US6174896B1/en not_active Expired - Lifetime
-
2004
- 2004-12-30 FR FR04C0032C patent/FR04C0032I2/fr active Active
-
2005
- 2005-01-28 LU LU91133C patent/LU91133I9/fr unknown
- 2005-07-11 NO NO2005016C patent/NO2005016I2/no unknown
-
2017
- 2017-11-06 NO NO2017055C patent/NO2017055I2/no unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE122004000048I2 (de) | Neue Chinuclidin-Derivate und diese enthaltende pharmazeutische Pr{parate | |
ATE170510T1 (de) | 3-(hydroxybenzylidenyl)-indolin-2-one und diese enthaltende arzneimittel | |
NO942953L (no) | 11-benzaldoksimestradienderivater, fremgangsmåte for deres fremstilling smat legemddel inneholdende slike | |
DE69111138D1 (de) | Heterocyclische Verbindungen mit antiemetischer und Migräne unterdrückender Wirkung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen. | |
DE68917485D1 (de) | Pyridazinon-Derivate und diese enthaltende pharmazeutische Zubereitungen. | |
EP1329218A4 (de) | Wirkstoffe zur vorbeugung und behandlung portaler hypertonie | |
DE69206787D1 (de) | 4-[(2-Benzothiazolyl)Methylamino]-alpha-(3,4-Difluorphenoxy)methyl-1-piperidenethanol | |
DE69321861D1 (de) | 3-Aminochroman-Spiroderivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzungen | |
FI911138A0 (fi) | Ny substituerad aminfoerening och foerfarande foer dess framstaellning. | |
ATE139523T1 (de) | Neue verbindungen und deren medizinale verwendung | |
DE69300318D1 (de) | Flavonderivate. | |
DK0580503T3 (da) | Aminoalkylchromoner, fremgangsmåde til fremstilling heraf samt midler indeholdende disse | |
NO903291D0 (no) | Renin-hemmende aminooligohydroksy-derivater. |