DE102010036193A1 - Apparatus for contactless transmission of electrical energy for bioreactor components - Google Patents

Apparatus for contactless transmission of electrical energy for bioreactor components

Info

Publication number
DE102010036193A1
DE102010036193A1 DE201010036193 DE102010036193A DE102010036193A1 DE 102010036193 A1 DE102010036193 A1 DE 102010036193A1 DE 201010036193 DE201010036193 DE 201010036193 DE 102010036193 A DE102010036193 A DE 102010036193A DE 102010036193 A1 DE102010036193 A1 DE 102010036193A1
Authority
DE
Germany
Prior art keywords
electrical energy
component
transmission
bioreactor
device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE201010036193
Other languages
German (de)
Inventor
Daniel Süß
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sartorius Stedim Biotech GmbH
Original Assignee
Sartorius Stedim Biotech GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sartorius Stedim Biotech GmbH filed Critical Sartorius Stedim Biotech GmbH
Priority to DE201010036193 priority Critical patent/DE102010036193A1/en
Publication of DE102010036193A1 publication Critical patent/DE102010036193A1/en
Application status is Pending legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F15/00Accessories for mixers ; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F15/00435Drives, e.g. for reciprocating motion; Transmissions; Brakes; Couplings
    • B01F15/00487Nature of the drive
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01FMIXING, e.g. DISSOLVING, EMULSIFYING, DISPERSING
    • B01F7/00Mixers with rotary stirring devices in fixed receptacles, i.e. movement of the receptacle not being meant to effect the mixing; Kneaders
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • HELECTRICITY
    • H01BASIC ELECTRIC ELEMENTS
    • H01FMAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F38/00Adaptations of transformers or inductances for specific applications or functions
    • H01F38/14Inductive couplings

Abstract

The present invention relates to a device for contactless transmission of electrical energy for bioreactor components.
Known bioreactors often have openings in order to ensure a power supply with cables or to move a stirrer shaft can. Such openings are uncertain and not reliable in terms of sterility aspects.
The inventive device for contactless transmission of electrical energy is equipped with a transmission component and a receiver component. The transmission component transmits on an inductive basis at least one component of a bioreactor electrical energy.
The device according to the invention is particularly suitable for bioreactors in the pharmaceutical, chemical, biotechnological or food industry.

Description

  • The invention relates to a device which contactlessly supplies energy-requiring components of a bioreactor with energy. Such a device is used in particular in disposable, mixing and bioreactors in the pharmaceutical, chemical, biotechnology or food industry.
  • Maintaining sterility is an important feature for safe production or research for the disposable, mixing and bioreactors used by the pharmaceutical, chemical, biotechnology or food industries.
  • From the DE 19 726 840 A1 a device for non-contact transmission of electrical energy is known, which has a feeding part with an induction coil, the electrical energy is supplied, and a plurality of fed parts, each having a arranged in a magnetic field generated by the induction coil induced coil. The powered parts differ in the load part, and each of the powered parts having different load parts has an electric power matching section corresponding to the single feeding part to receive electric power in response to the load part from the feeding part. The individual feeding part is used, whereby only the fed parts take into account the load difference.
  • From the DE 10 2008 010 427 B4 a bioreactor is known, comprising a container, a shaft housing for passing a shaft through a wall, an in the interior of the container connected to the shaft agitator, arranged outside the container, connectable to the shaft drive, wherein the shaft in the shaft housing via at least a ball bearing and sealed by at least one seal against the shaft housing, characterized in that the seal is formed as a radial shaft seal with two longitudinally of the shaft arranged one behind the other, on the shaft dry running sealing lips, that the radial shaft seal to the interior of the container out a has closed end face, which merges in the radial direction in a sealing lip designed as a protective lip, and that the radial shaft seal to the outside drive has a sealing lip which is pressed by a spring ring sealingly against the shaft surface. The disadvantage here is that an opening in the bioreactor for the agitator shaft must be present through the lying outside the bioreactor drive motor for the stirrer shaft. Thus, sterility is not completely ensured by, for example, design errors or faulty seals.
  • From the DE 10 2008 025 507.6 A1 a bioreactor is known in which the drive does not affect the sterility of the container interior of the disposable container. This is accomplished by a mixing system consisting of a disposable flexible-walled container and a mixing device having an encapsulated drive and a mixing shaft within the bioreactor. It is disadvantageous that the drive motor is present in the interior of the bioreactor, since it can, for example, to thermal or similar influences, such as when the engine heats up and thus influences the medium in the bioreactor. Damage to the engine is also conceivable if high temperatures or humidities prevail within the bioreactor.
  • The invention is therefore based on the object to provide a device with which energy-requiring bioreactor components are supplied with the maintenance of sterility safe and reliable with electrical energy.
  • The object is achieved by a device according to claim 1. The device according to the invention transfers contactless electrical energy for one or more bioreactor components. Through a transmitter component, energy is inductively supplied to a receiver component. The transmitter component is placed outside the bioreactor. A stationary placement is possible. Due to the inductive energy transfer to the receiver component, it is possible without cabling to supply bioreactor components with energy. This is particularly advantageous when high humidity or sour ambient air prevail. In the contactless transmission, the transmitter and receiver components are preferably axially opposite and are arranged at a defined distance from each other. This distance is particularly preferably between 0 mm and 5 mm. The transmission is independent of the axial angular position of the components with each other. Ideally, transmitted signals behave as if there were a direct electrical connection from the source to the load.
  • According to a preferred embodiment of the invention, the at least one component is arranged within the bioreactor. Thus, the receiver component which supplies the at least one component with electrical energy is preferably also inside the bioreactor.
  • In a further particularly preferred embodiment of the invention, the bioreactor is made of flexible plastic. is trained. such Disposable bioreactors must be cost-effective to implement. The transmitter component may be stationary and reusable. Thus, only the receiver component needs to be discarded after use. In addition, implementation of wireless inductive power supply through a flexible plastic wall is easy to implement. The efficiency can thus be kept high and it comes to low losses.
  • In a further advantageous embodiment of the invention, the at least one component is a sensor device, a drive for a mixer shaft, a valve system, a port system, a gassing device or another component which requires energy. The component has the receiver component, which, for example, can be integrated directly into the component.
  • In an advantageous embodiment of the invention, the mixer shaft is set in rotation. But it is also conceivable, for example, a linear up and down movement.
  • According to a further particularly preferred embodiment of the invention, the receptor component can be sterilized by radiation while retaining its functionality. Thus, for example, the usual for disposable bioreactors gamma radiation is applicable. Likewise, sterilization by means of ionizing radiation, UV-C, beta or electron radiation can be realized.
  • According to a further preferred embodiment, the transmission component is an induction coil and the receiver component is an induced coil. The induction coil is in this case fed with electricity and generates a magnetic field.
  • According to a further particularly advantageous embodiment of the invention, the receiver component has at least one accumulator which stores the electrical energy supplied by the transmission component and delivers it to a motor for starting or operating the bioreactor component (e). Thus, for example, certain bioreactor components within the bioreactor may already be powered, and it is not necessary for the receiver of the bioreactor to acquire a transmission component.
  • QUOTES INCLUDE IN THE DESCRIPTION
  • This list of the documents listed by the applicant has been generated automatically and is included solely for the better information of the reader. The list is not part of the German patent or utility model application. The DPMA assumes no liability for any errors or omissions.
  • Cited patent literature
    • DE 19726840 A1 [0003]
    • DE 102008010427 B4 [0004]
    • DE 102008025507 A1 [0005]

Claims (9)

  1. Device for contactless transmission of electrical energy with a transmission component and a receiver component, wherein at least one component of a bioreactor on an inductive basis, electrical energy can be supplied.
  2. A device for contactless transmission of electrical energy according to claim 1, wherein the at least one component is arranged within the bioreactor.
  3. Device for contactless transmission of electrical energy according to one of the preceding claims, wherein the bioreactor is formed of flexible plastic.
  4. The apparatus for contactless transmission of electrical energy according to one of the preceding claims, wherein the at least one component is a sensor device, a drive for a mixer shaft, a valve, a port system or a gassing device.
  5. A non-contact electrical energy transmission device according to claim 4, wherein the mixer shaft is rotatable.
  6. Apparatus for contactless transmission of electrical energy according to any one of the preceding claims, wherein the receiver component is sterilized by radiation while maintaining its functionality.
  7. The apparatus for contactless transmission of electrical energy according to claim 6, wherein the radiation is ionizing radiation, gamma radiation or electron radiation.
  8. A non-contact electrical energy transmission device according to any one of the preceding claims, wherein the transmission component is an induction coil and the receiver component is an induced coil.
  9. Apparatus for contactless transmission of electrical energy according to any one of the preceding claims, wherein the receiver component comprises an accumulator.
DE201010036193 2010-09-02 2010-09-02 Apparatus for contactless transmission of electrical energy for bioreactor components Pending DE102010036193A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE201010036193 DE102010036193A1 (en) 2010-09-02 2010-09-02 Apparatus for contactless transmission of electrical energy for bioreactor components

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE201010036193 DE102010036193A1 (en) 2010-09-02 2010-09-02 Apparatus for contactless transmission of electrical energy for bioreactor components
PCT/EP2011/003941 WO2012028242A1 (en) 2010-09-02 2011-08-05 Device for transmitting electrical energy for bioreactor components without contact

Publications (1)

Publication Number Publication Date
DE102010036193A1 true DE102010036193A1 (en) 2012-03-08

Family

ID=44651606

Family Applications (1)

Application Number Title Priority Date Filing Date
DE201010036193 Pending DE102010036193A1 (en) 2010-09-02 2010-09-02 Apparatus for contactless transmission of electrical energy for bioreactor components

Country Status (2)

Country Link
DE (1) DE102010036193A1 (en)
WO (1) WO2012028242A1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19726840A1 (en) 1996-06-25 1998-01-02 Matsushita Electric Works Ltd Contactless electrical energy transmission device
DE102008025507A1 (en) 2008-05-28 2009-12-03 Sartorius Stedim Biotech Gmbh Mixing system
DE102008010427B4 (en) 2008-02-21 2010-05-12 Sartorius Stedim Biotech Gmbh bioreactor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005118771A2 (en) * 2004-06-04 2005-12-15 Xcellerex, Inc. Disposable bioreactor systems and methods
DE102006022651B3 (en) * 2006-05-12 2007-10-18 Sartorius Biotech Gmbh Container used as a disposable bio-reactor comprises a mixer made from parts of an inflatable structure formed as a mixer guiding structure and held in position by the guiding structure
US9109193B2 (en) * 2007-07-30 2015-08-18 Ge Healthcare Bio-Sciences Corp. Continuous perfusion bioreactor system

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19726840A1 (en) 1996-06-25 1998-01-02 Matsushita Electric Works Ltd Contactless electrical energy transmission device
DE102008010427B4 (en) 2008-02-21 2010-05-12 Sartorius Stedim Biotech Gmbh bioreactor
DE102008025507A1 (en) 2008-05-28 2009-12-03 Sartorius Stedim Biotech Gmbh Mixing system

Also Published As

Publication number Publication date
WO2012028242A1 (en) 2012-03-08

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