DE1007662T1 - METHOD FOR INDUCING APOPTOTIC CELL DEAD IN MALIGNANT CELLS BY REDUCING THE RB PROTEIN RATIO INDUCING APOPTOSIS - Google Patents

METHOD FOR INDUCING APOPTOTIC CELL DEAD IN MALIGNANT CELLS BY REDUCING THE RB PROTEIN RATIO INDUCING APOPTOSIS

Info

Publication number
DE1007662T1
DE1007662T1 DE1007662T DE98902970T DE1007662T1 DE 1007662 T1 DE1007662 T1 DE 1007662T1 DE 1007662 T DE1007662 T DE 1007662T DE 98902970 T DE98902970 T DE 98902970T DE 1007662 T1 DE1007662 T1 DE 1007662T1
Authority
DE
Germany
Prior art keywords
inducing
reducing
malignant cells
apoptotic cell
protein ratio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE1007662T
Other languages
German (de)
Inventor
Michael Strauss
Volker Sandig
Jiri Bartek
Jiri Lukas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE1007662T1 publication Critical patent/DE1007662T1/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4736—Retinoblastoma protein
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
DE1007662T 1997-02-20 1998-02-20 METHOD FOR INDUCING APOPTOTIC CELL DEAD IN MALIGNANT CELLS BY REDUCING THE RB PROTEIN RATIO INDUCING APOPTOSIS Pending DE1007662T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK18397 1997-02-20
US91922697A 1997-08-28 1997-08-28
PCT/DK1998/000068 WO1998037190A1 (en) 1997-02-20 1998-02-20 Method for induction of apoptotic cell death in malignant cells, through reduction of the rb to apoptosis inducing proteins ratio

Publications (1)

Publication Number Publication Date
DE1007662T1 true DE1007662T1 (en) 2001-04-19

Family

ID=26063484

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1007662T Pending DE1007662T1 (en) 1997-02-20 1998-02-20 METHOD FOR INDUCING APOPTOTIC CELL DEAD IN MALIGNANT CELLS BY REDUCING THE RB PROTEIN RATIO INDUCING APOPTOSIS

Country Status (8)

Country Link
EP (1) EP1007662A1 (en)
JP (1) JP2001524812A (en)
CN (1) CN1248290A (en)
AU (1) AU732794B2 (en)
CA (1) CA2283090A1 (en)
DE (1) DE1007662T1 (en)
ES (1) ES2150891T1 (en)
WO (1) WO1998037190A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2794771B1 (en) * 1999-06-11 2001-08-10 Aventis Pharma Sa RECOMBINANT ADENOVIRUSES ENCODING THE IODINE SPECIFIC TRANSPORTER (NIS)
KR101968637B1 (en) 2012-12-07 2019-04-12 삼성전자주식회사 Flexible semiconductor device and method of manufacturing the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4502096A (en) * 1994-11-11 1996-06-06 Arch Development Corporation A process of inhibiting non-neoplastic pathological cell proliferation
US6033847A (en) * 1995-02-06 2000-03-07 St. Jude Children's Research Hospital InK4c-p18 and InK4d-p19, inhibitors of cyclin-dependent kinases CDK4 and CDK6, and uses thereof
DE19539130C2 (en) * 1995-02-28 1999-05-12 Max Planck Gesellschaft Agents for the therapy of tumors and other hyperplasias
WO1997003635A2 (en) * 1995-07-17 1997-02-06 Board Of Regents, The University Of Texas System p16 EXPRESSION CONSTRUCTS AND THEIR APPLICATION IN CANCER THERAPY

Also Published As

Publication number Publication date
WO1998037190A1 (en) 1998-08-27
CA2283090A1 (en) 1998-08-27
ES2150891T1 (en) 2000-12-16
JP2001524812A (en) 2001-12-04
AU5983198A (en) 1998-09-09
EP1007662A1 (en) 2000-06-14
CN1248290A (en) 2000-03-22
AU732794B2 (en) 2001-05-03

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