DD236735A5 - Verfahren zur herstellung von cephalosporinverbindungen - Google Patents

Verfahren zur herstellung von cephalosporinverbindungen Download PDF

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Publication number
DD236735A5
DD236735A5 DD85274832A DD27483285A DD236735A5 DD 236735 A5 DD236735 A5 DD 236735A5 DD 85274832 A DD85274832 A DD 85274832A DD 27483285 A DD27483285 A DD 27483285A DD 236735 A5 DD236735 A5 DD 236735A5
Authority
DD
German Democratic Republic
Prior art keywords
amino
thiadiazol
cephem
carboxylate
group
Prior art date
Application number
DD85274832A
Other languages
German (de)
English (en)
Inventor
Masahisa Oka
Haruhiro Yamashita
Takayuki Natto
Jun Okumura
Original Assignee
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by �������`�����@�������k�� filed Critical �������`�����@�������k��
Publication of DD236735A5 publication Critical patent/DD236735A5/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/08—1,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DD85274832A 1984-04-09 1985-04-03 Verfahren zur herstellung von cephalosporinverbindungen DD236735A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59794184A 1984-04-09 1984-04-09

Publications (1)

Publication Number Publication Date
DD236735A5 true DD236735A5 (de) 1986-06-18

Family

ID=24393575

Family Applications (3)

Application Number Title Priority Date Filing Date
DD85287524A DD249024A5 (de) 1984-04-09 1985-04-03 Verfahren zur herstellung von cephalosporinverbindungen
DD85274832A DD236735A5 (de) 1984-04-09 1985-04-03 Verfahren zur herstellung von cephalosporinverbindungen
DD86287525A DD251752A5 (de) 1984-04-09 1986-03-03 Verfahren zur herstellung von cephalosporinverbindungen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DD85287524A DD249024A5 (de) 1984-04-09 1985-04-03 Verfahren zur herstellung von cephalosporinverbindungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DD86287525A DD251752A5 (de) 1984-04-09 1986-03-03 Verfahren zur herstellung von cephalosporinverbindungen

Country Status (31)

Country Link
JP (4) JPS615084A (xx)
KR (1) KR870002166B1 (xx)
AR (1) AR244694A1 (xx)
AT (1) AT388735B (xx)
AU (2) AU580990B2 (xx)
BE (1) BE902148A (xx)
CA (3) CA1276929C (xx)
CH (1) CH669197A5 (xx)
DD (3) DD249024A5 (xx)
DE (1) DE3512225A1 (xx)
DK (1) DK155985A (xx)
ES (4) ES8607318A1 (xx)
FI (1) FI84830C (xx)
FR (1) FR2563832B1 (xx)
GB (3) GB2157293B (xx)
GR (1) GR850883B (xx)
HU (2) HU204277B (xx)
IE (2) IE58408B1 (xx)
IL (1) IL74826A (xx)
IT (1) IT1190353B (xx)
LU (1) LU85840A1 (xx)
MY (1) MY101940A (xx)
NL (1) NL192925C (xx)
NZ (1) NZ211659A (xx)
OA (1) OA07985A (xx)
PT (1) PT80246B (xx)
RU (1) RU2056425C1 (xx)
SE (4) SE466205B (xx)
SU (4) SU1436882A3 (xx)
YU (2) YU46151B (xx)
ZA (1) ZA852236B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61145186A (ja) * 1984-12-20 1986-07-02 Meiji Seika Kaisha Ltd 新規セフエム化合物及びその製造法
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
WO1987003875A1 (en) * 1985-12-26 1987-07-02 Eisai Co., Ltd. Cephalosporin derivatives
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
AU614723B2 (en) * 1986-10-13 1991-09-12 Eisai Co. Ltd. 3-propenylcephem derivative
JPH085897B2 (ja) * 1986-11-06 1996-01-24 エーザイ株式会社 ３−プロペニルセフェム誘導体
FR2622585B1 (fr) * 1987-11-03 1991-04-19 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus
ES2013403A6 (es) * 1988-03-16 1990-05-01 Eisai Co Ltd Procedimiento para preparar derivados de cefem.
JPH0699449B2 (ja) * 1988-03-16 1994-12-07 エーザイ株式会社 セフェム誘導体の合成中間体
FR2655042B1 (fr) * 1989-11-29 1994-01-21 Adir Cie Nouvelles benzothiazolinones substituees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2663332B1 (fr) * 1990-06-15 1997-11-07 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
US5126336A (en) * 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
AT396108B (de) * 1991-08-21 1993-06-25 Biochemie Gmbh Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
JPH0741484A (ja) * 1993-07-29 1995-02-10 Katayama Seiyakushiyo:Kk セフェム化合物及び抗菌剤
EP0723966A4 (en) * 1994-08-16 1997-01-29 Meiji Seika Co NEW DERIVATIVES FROM CEPHEM
JP4033630B2 (ja) 1998-06-22 2008-01-16 バジリア ファルマスーチカ アーゲー プロペニルセファロスポリン誘導体
WO2005026176A1 (ja) 2003-09-09 2005-03-24 Nippon Chemical Industrial Co.,Ltd. ３−クロロメチル-３-セフェム誘導体の製造方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1342241A (en) * 1970-01-23 1974-01-03 Glaxo Lab Ltd Cephalosporin compounds
US4390534A (en) * 1978-12-29 1983-06-28 Fujisawa Pharmaceutical Co., Ltd. Cephem and cepham compounds
EP0025017A1 (de) * 1979-08-28 1981-03-11 Ciba-Geigy Ag Polyazathiaverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate enthaltend solche Verbindungen und Verwendung von letzteren
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
GR75644B (xx) * 1980-06-18 1984-08-02 Fujisawa Pharmaceutical Co
GR78245B (xx) * 1980-09-12 1984-09-26 Ciba Geigy Ag
US4521413A (en) * 1981-09-14 1985-06-04 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives

Also Published As

Publication number Publication date
LU85840A1 (fr) 1985-12-16
SE505256C2 (sv) 1997-07-21
IE58403B1 (en) 1993-09-22
GB2157293B (en) 1988-10-05
SU1375140A3 (ru) 1988-02-15
JPS615084A (ja) 1986-01-10
ES551551A0 (es) 1987-07-01
FR2563832B1 (fr) 1989-08-18
ES8706694A1 (es) 1987-07-01
GB2194789B (en) 1988-10-12
AU610278B2 (en) 1991-05-16
GB8721347D0 (en) 1987-10-14
ES8800949A1 (es) 1987-12-01
SE466205B (sv) 1992-01-13
JPH0262557B2 (xx) 1990-12-26
GR850883B (xx) 1985-11-25
ES8706155A1 (es) 1987-06-01
SE8901224L (sv) 1989-04-06
GB2157293A (en) 1985-10-23
BE902148A (fr) 1985-10-09
SE8501680D0 (sv) 1985-04-03
CA1276929C (en) 1990-11-27
FI84830C (fi) 1992-01-27
ES551550A0 (es) 1987-06-01
IT1190353B (it) 1988-02-16
SE8901225L (sv) 1989-04-06
JPH0350754B2 (xx) 1991-08-02
JPS61143391A (ja) 1986-07-01
CA1340638C (en) 1999-07-06
SE8501680L (sv) 1985-10-10
IT8520267A0 (it) 1985-04-05
SU1436882A3 (ru) 1988-11-07
SE470260B (sv) 1993-12-20
ES8607318A1 (es) 1986-06-16
ES557060A0 (es) 1987-12-01
AT388735B (de) 1989-08-25
SE470259B (sv) 1993-12-20
DE3512225A1 (de) 1985-10-17
SU1367858A3 (ru) 1988-01-15
AR244694A1 (es) 1993-11-30
GB2194790B (en) 1988-10-05
IL74826A0 (en) 1985-07-31
CH669197A5 (de) 1989-02-28
PT80246A (en) 1985-05-01
SU1487814A3 (ru) 1989-06-15
FI84830B (fi) 1991-10-15
YU46151B (sh) 1993-05-28
DE3512225C2 (xx) 1990-02-22
YU46213B (sh) 1993-05-28
HU193750B (en) 1987-11-30
GB2194789A (en) 1988-03-16
IE850866L (en) 1985-10-09
SE8901224D0 (sv) 1989-04-06
IL74826A (en) 1990-01-18
KR870002166B1 (ko) 1987-12-14
JPS61143387A (ja) 1986-07-01
SE8901225D0 (sv) 1989-04-06
DD249024A5 (de) 1987-08-26
HU204277B (en) 1991-12-30
NL192925C (nl) 1998-05-07
NL192925B (nl) 1998-01-05
DK155985D0 (da) 1985-04-03
KR850007424A (ko) 1985-12-04
DD251752A5 (de) 1987-11-25
AU4086285A (en) 1985-10-17
NZ211659A (en) 1988-11-29
MY101940A (en) 1992-02-15
SE8901226L (sv) 1989-04-06
AU580990B2 (en) 1989-02-09
FI851379A0 (fi) 1985-04-04
ZA852236B (en) 1985-11-27
GB2194790A (en) 1988-03-16
CA1340672C (en) 1999-07-20
YU118987A (en) 1988-10-31
SE8901226D0 (sv) 1989-04-06
NL8501002A (nl) 1985-11-01
FR2563832A1 (fr) 1985-11-08
GB8508846D0 (en) 1985-05-09
FI851379L (fi) 1985-10-10
RU2056425C1 (ru) 1996-03-20
OA07985A (fr) 1987-01-31
AU2504188A (en) 1989-03-02
JPH0351716B2 (xx) 1991-08-07
DK155985A (da) 1985-10-10
ES542013A0 (es) 1986-06-16
GB8721346D0 (en) 1987-10-14
ATA103985A (de) 1989-01-15
JPS61143390A (ja) 1986-07-01
PT80246B (pt) 1987-10-20
IE58408B1 (en) 1993-09-22
JPH0357106B2 (xx) 1991-08-30
HUT37622A (en) 1986-01-23
YU60085A (en) 1987-12-31

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Legal Events

Date Code Title Description
IF04 In force in the year 2004

Expiry date: 20050404