DD215542A5 - Verfahren zur herstellung von 4-cyano-pyridazinen - Google Patents

Verfahren zur herstellung von 4-cyano-pyridazinen

Info

Publication number
DD215542A5
DD215542A5 DD84259679A DD25967984A DD215542A5 DD 215542 A5 DD215542 A5 DD 215542A5 DD 84259679 A DD84259679 A DD 84259679A DD 25967984 A DD25967984 A DD 25967984A DD 215542 A5 DD215542 A5 DD 215542A5
Authority
DD
German Democratic Republic
Prior art keywords
group
formula
carbon atoms
cyano
compound
Prior art date
Application number
DD84259679A
Other languages
German (de)
English (en)
Inventor
Kathleen Biziere
Jean-Paul Kan
Camille-Georges Wermuth
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8301366A external-priority patent/FR2540115B1/fr
Priority claimed from FR8318433A external-priority patent/FR2555178B1/fr
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of DD215542A5 publication Critical patent/DD215542A5/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DD84259679A 1983-01-28 1984-01-27 Verfahren zur herstellung von 4-cyano-pyridazinen DD215542A5 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8301366A FR2540115B1 (fr) 1983-01-28 1983-01-28 Derive de la pyridazine ayant une action psychotrope, son mode de preparation et les medicaments en contenant
FR8318433A FR2555178B1 (fr) 1983-11-18 1983-11-18 Derives cyanes de la pyridazine ayant une action psychotrope, leur mode de preparation et les medicaments en contenant

Publications (1)

Publication Number Publication Date
DD215542A5 true DD215542A5 (de) 1984-11-14

Family

ID=26223263

Family Applications (1)

Application Number Title Priority Date Filing Date
DD84259679A DD215542A5 (de) 1983-01-28 1984-01-27 Verfahren zur herstellung von 4-cyano-pyridazinen

Country Status (25)

Country Link
US (2) US4565814A (es)
EP (1) EP0116494B1 (es)
KR (1) KR910000639B1 (es)
AU (1) AU566352B2 (es)
CA (1) CA1218655A (es)
CS (1) CS274405B2 (es)
DD (1) DD215542A5 (es)
DE (1) DE3469026D1 (es)
DK (3) DK159969C (es)
ES (1) ES8500253A1 (es)
FI (1) FI77453C (es)
GR (1) GR81682B (es)
HU (1) HU192975B (es)
IE (1) IE56750B1 (es)
IL (1) IL70755A (es)
MA (1) MA20019A1 (es)
NO (1) NO840329L (es)
NZ (1) NZ206957A (es)
OA (1) OA07645A (es)
PH (1) PH21476A (es)
PL (1) PL143994B1 (es)
PT (1) PT77994B (es)
SG (1) SG9389G (es)
SU (1) SU1274623A3 (es)
YU (1) YU14184A (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2540113A1 (fr) * 1983-01-27 1984-08-03 Sanofi Sa Acides derives de la pyridazine actifs sur le systeme nerveux central
DE3672536D1 (de) * 1985-06-14 1990-08-16 Lilly Co Eli Fungizide pyridazine.
US5106973A (en) * 1987-11-23 1992-04-21 Janssen Pharmaceutica N.V. Pyridzainamine derivatives
RU2224520C2 (ru) 1998-08-20 2004-02-27 Тояма Кемикал Ко., Лтд. Азотсодержащие гетероциклические производные карбоксамида или их соли и противовирусные средства, включающие их
DK1144388T3 (da) 1999-01-22 2010-05-25 Elan Pharm Inc Acyl-derivater, som behandler VLA-4-relaterede lidelser
TW200307671A (en) 2002-05-24 2003-12-16 Elan Pharm Inc Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins
TWI281470B (en) 2002-05-24 2007-05-21 Elan Pharm Inc Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins
AU2005260102A1 (en) * 2004-05-08 2006-01-12 Novartis International Pharmaceutical Ltd. 3-aryl-5,6-disubstituted pyridazines
EP1741709A1 (en) * 2005-06-28 2007-01-10 Sanofi-Aventis Deutschland GmbH Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals
KR20080059268A (ko) 2005-09-29 2008-06-26 엘란 파마슈티칼스, 인크. Vla-4에 의해 매개되는 백혈구 부착을 억제하는피리미디닐 아미드 화합물
ATE502031T1 (de) 2005-09-29 2011-04-15 Elan Pharm Inc Carbamatverbindungen, die die durch vla-4 vermittelte leukozytenadhäsion inhibieren
CA2643838A1 (en) 2006-02-27 2007-09-07 Elan Pharmaceuticals, Inc. Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by vla-4
CA2760151A1 (en) 2009-04-27 2010-11-04 Elan Pharmaceuticals, Inc. Pyridinone antagonists of alpha-4 integrins
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
AR081626A1 (es) 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos
EP2560488B1 (en) 2010-04-23 2015-10-28 Cytokinetics, Inc. Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1345880A (en) * 1971-06-18 1974-02-06 Cepbepe Pyridazine derivatives
FR2510998B1 (fr) * 1981-08-07 1986-01-10 Sanofi Sa Nouveaux derives amines de la pyridazine, leur procede de preparation et les medicaments, a action desinhibitrice, qui en comportent
FR2510997A1 (fr) * 1981-08-10 1983-02-11 Sanofi Sa Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
FR2539739B1 (fr) * 1983-01-24 1985-11-22 Sanofi Sa Nouveaux derives de la naphtyl pyridazine actifs sur le systeme nerveux central, procede de preparation de ces derives et medicaments en contenant

Also Published As

Publication number Publication date
PL143994B1 (en) 1988-04-30
DK159969B (da) 1991-01-07
FI77453B (fi) 1988-11-30
DK621589D0 (da) 1989-12-08
FI840349A0 (fi) 1984-01-27
US4565814A (en) 1986-01-21
GR81682B (es) 1984-12-12
ES529108A0 (es) 1984-10-01
DK25984D0 (da) 1984-01-20
DK162218C (da) 1992-03-02
PH21476A (en) 1987-10-28
KR840007587A (ko) 1984-12-08
IL70755A (en) 1987-03-31
NO840329L (no) 1984-07-30
FI77453C (fi) 1989-03-10
AU2372884A (en) 1984-08-02
DK162219C (da) 1992-03-02
FI840349A (fi) 1984-07-29
SU1274623A3 (ru) 1986-11-30
AU566352B2 (en) 1987-10-15
US4631280A (en) 1986-12-23
IE840148L (en) 1984-07-28
MA20019A1 (fr) 1984-10-01
IL70755A0 (en) 1984-04-30
ES8500253A1 (es) 1984-10-01
DK621589A (da) 1989-12-08
PL245932A1 (en) 1985-05-21
YU14184A (en) 1986-10-31
DK621689D0 (da) 1989-12-08
CA1218655A (en) 1987-03-03
DK162219B (da) 1991-09-30
DK621689A (da) 1989-12-08
CS61484A2 (en) 1990-09-12
NZ206957A (en) 1987-06-30
DK25984A (da) 1984-07-29
HU192975B (en) 1987-08-28
CS274405B2 (en) 1991-04-11
DE3469026D1 (en) 1988-03-03
OA07645A (fr) 1985-05-23
EP0116494B1 (fr) 1988-01-27
KR910000639B1 (ko) 1991-01-31
EP0116494A1 (fr) 1984-08-22
IE56750B1 (en) 1991-12-04
SG9389G (en) 1989-07-07
PT77994A (fr) 1984-02-01
DK159969C (da) 1991-05-27
DK162218B (da) 1991-09-30
PT77994B (fr) 1986-04-10

Similar Documents

Publication Publication Date Title
DD215542A5 (de) Verfahren zur herstellung von 4-cyano-pyridazinen
DE2504565A1 (de) Neue derivate von 1h-imidazo(4,5-c) pyridin-7-carboxylsaeuren und -saeureestern
DD202715A5 (de) Verfahren zur herstellung von substituierten derivaten des pyridazin
DE2503002A1 (de) Substituierte piperidinderivate, ein verfahren zu ihrer herstellung sowie arzneimittel
DD213213A5 (de) Verfahren zur herstellung von 4-methyl-6-phenyl-pyridazin-derivaten
DE2604748A1 (de) Aminoderivate von imidazo(4,5-b) pyridinen
DE2313227A1 (de) Neue isoindolinderivate, ihre herstellung und die medizinischen zusammensetzungen, die sie enthalten
DE2458638C2 (de) 4'-substituierte 2-Methyl-3-piperidinopropiophenonderivate, Verfahren zu deren Herstellung und pharmakologische Zubereitungen, welche diese enthalten
DE68905171T2 (de) Benzol-derivate, ihre herstellung und pharmazeutische zusammensetzungen, die diese enthalten.
DE3688917T2 (de) Derivate eines Aminoketons.
EP0152868A2 (de) Isoxazol-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2929760C2 (es)
DE3438244C2 (es)
DE2219171A1 (de) Substituierte Cycloalkyl-lactamimide
DE2825861C2 (es)
DE2432392C3 (de) Tris-(2-hydroxyäthyl)-ammonium-orthokresoxyazetat, Verfahren zu dessen Herstellung und Arzneimittel auf dessen Basis
DD154487A5 (de) Verfahren zur herstellung von 1-benzoxepin-5(2h)-on-derivaten
DE2521920A1 (de) Neue derivate von 1h-triazolo(4,5-c) pyridin-7-carbonsaeuren und -saeureestern
DD238793A5 (de) Verfahren zur herstellung von amin-derivaten des pyrazins
DE1957639A1 (de) Neue heterocyclische Verbindungen und Verfahren zu deren Herstellung
DE69124025T2 (de) Organosilan-Derivate, diese enthaltende pharmazeutische Mittel und Verfahren zu ihrer Herstellung
EP0199323A2 (de) 4-Aminoalkylidensubstituierte 3-Aryl-5(4H)-isoxazolone, Verfahren zur ihrer Herstellung, diese Verbindungen enthaltende Arzneimittel und ihre Verwendung
EP0240854A1 (de) Bis-tertiärbutylamino-substituierte 1,3,5-Triazinderivate, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende Arzneimittel und ihre Verwendung
EP0045521B1 (de) Pyrazolobenzazepine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
EP0303179A1 (de) Neue 1,2-Diamino-Verbindungen, Verfahren zu ihrer Herstellung sowie Arzneimittel, die diese Verbindungen enthalten

Legal Events

Date Code Title Description
ENJ Ceased due to non-payment of renewal fee