CZ418597A3 - 1,6-disubstituované izochromany pro léčbu bolestí hlavy při migréně - Google Patents
1,6-disubstituované izochromany pro léčbu bolestí hlavy při migréně Download PDFInfo
- Publication number
- CZ418597A3 CZ418597A3 CZ974185A CZ418597A CZ418597A3 CZ 418597 A3 CZ418597 A3 CZ 418597A3 CZ 974185 A CZ974185 A CZ 974185A CZ 418597 A CZ418597 A CZ 418597A CZ 418597 A3 CZ418597 A3 CZ 418597A3
- Authority
- CZ
- Czechia
- Prior art keywords
- defined above
- ethyl
- isochroman
- alkyl
- piperazinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74195P | 1995-06-30 | 1995-06-30 | |
| US1123496P | 1996-02-06 | 1996-02-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CZ418597A3 true CZ418597A3 (cs) | 1998-06-17 |
Family
ID=26668092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CZ974185A CZ418597A3 (cs) | 1995-06-30 | 1996-06-07 | 1,6-disubstituované izochromany pro léčbu bolestí hlavy při migréně |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0836599A1 (fi) |
| JP (1) | JPH11509532A (fi) |
| AU (1) | AU6252296A (fi) |
| BR (1) | BR9609631A (fi) |
| CA (1) | CA2225282A1 (fi) |
| CZ (1) | CZ418597A3 (fi) |
| FI (1) | FI974640A (fi) |
| MX (1) | MX9710260A (fi) |
| NO (1) | NO976112L (fi) |
| PL (1) | PL324319A1 (fi) |
| SK (1) | SK164297A3 (fi) |
| WO (1) | WO1997002259A1 (fi) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2370270A (en) * | 2000-12-20 | 2002-06-26 | Lilly Co Eli | Pharmaceutical compounds |
| US7335660B2 (en) | 2001-12-19 | 2008-02-26 | Eli Lilly And Company | Isochroman compounds for treatment of CNS disorders |
| GB0130339D0 (en) * | 2001-12-19 | 2002-02-06 | Lilly Co Eli | Isochroman compounds |
| US7110576B2 (en) | 2002-12-30 | 2006-09-19 | Pitney Bowes Inc. | System and method for authenticating a mailpiece sender |
| BRPI0510642A (pt) | 2004-05-05 | 2007-11-20 | Hoffmann La Roche | arilsulfonil benzodioxanos úteis para modulação do receptor de 5-ht6, do receptor de 5ht2a ou ambos |
| NZ555845A (en) | 2004-12-21 | 2009-09-25 | Hoffmann La Roche | Tetralin and indane derivatives and uses thereof |
| BRPI0519709A2 (pt) | 2004-12-21 | 2009-03-10 | Hoffmann La Roche | derivados de tetralina e indano e usos dos mesmos como antagonistas de 5-ht |
| RU2396266C2 (ru) | 2004-12-21 | 2010-08-10 | Ф. Хоффманн-Ля Рош Аг | Производные хромана и их применения при лечении заболеваний цнс |
| RU2396264C2 (ru) | 2004-12-21 | 2010-08-10 | Ф. Хоффманн-Ля Рош Аг | Производные хромана и их применение в качестве лигандов 5-нт рецептора |
| BRPI0515835A (pt) | 2004-12-21 | 2008-08-12 | Hoffmann La Roche | derivados de tetralina e de indano e seus usos |
| CA2628173A1 (en) | 2005-11-03 | 2007-05-10 | F. Hoffmann-La Roche Ag | Arylsulfonylchromans as 5-ht6 inhibitors indolylmaleimide derivatives as protein kinase inhibitors |
| WO2007147771A2 (en) | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Tetralin and indane derivatives and uses thereof |
| WO2007147762A1 (en) | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Arylsulfonamidyl tetralin derivatives and uses thereof |
| KR101060451B1 (ko) | 2006-06-20 | 2011-08-29 | 에프. 호프만-라 로슈 아게 | 아릴설폰일 나프탈렌 유도체 및 이의 용도 |
| KR20110125258A (ko) * | 2009-03-05 | 2011-11-18 | 스미또모 가가꾸 가부시끼가이샤 | 할로겐 치환 벤젠디메탄올의 제조 방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1552004A (en) * | 1976-05-26 | 1979-09-05 | Takeda Chemical Industries Ltd | Isochroman derivatives |
| CN1046507C (zh) * | 1993-12-28 | 1999-11-17 | 法玛西雅厄普约翰美国公司 | 用于治疗中枢神经系统和心血管疾病的杂环化合物 |
-
1996
- 1996-06-07 MX MX9710260A patent/MX9710260A/es unknown
- 1996-06-07 JP JP9505135A patent/JPH11509532A/ja active Pending
- 1996-06-07 AU AU62522/96A patent/AU6252296A/en not_active Abandoned
- 1996-06-07 SK SK1642-97A patent/SK164297A3/sk unknown
- 1996-06-07 CA CA002225282A patent/CA2225282A1/en not_active Abandoned
- 1996-06-07 CZ CZ974185A patent/CZ418597A3/cs unknown
- 1996-06-07 EP EP96921264A patent/EP0836599A1/en not_active Withdrawn
- 1996-06-07 BR BR9609631A patent/BR9609631A/pt not_active Application Discontinuation
- 1996-06-07 WO PCT/US1996/008681 patent/WO1997002259A1/en not_active Application Discontinuation
- 1996-06-07 PL PL96324319A patent/PL324319A1/xx unknown
-
1997
- 1997-12-29 NO NO976112A patent/NO976112L/no unknown
- 1997-12-30 FI FI974640A patent/FI974640A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR9609631A (pt) | 1999-03-02 |
| NO976112D0 (no) | 1997-12-29 |
| AU6252296A (en) | 1997-02-05 |
| SK164297A3 (en) | 1998-09-09 |
| NO976112L (no) | 1998-03-02 |
| CA2225282A1 (en) | 1997-01-23 |
| FI974640A0 (fi) | 1997-12-30 |
| EP0836599A1 (en) | 1998-04-22 |
| FI974640A (fi) | 1997-12-30 |
| PL324319A1 (en) | 1998-05-25 |
| WO1997002259A1 (en) | 1997-01-23 |
| MX9710260A (es) | 1998-03-29 |
| JPH11509532A (ja) | 1999-08-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2013254657B2 (en) | Novel compounds | |
| AU701420B2 (en) | Novel piperazides derived from arylpiperazine, processes for their preparation, their use as medicaments and pharmaceutical compositions comprising them | |
| TW536537B (en) | Benzoxazine antimicrobial agents | |
| CZ418597A3 (cs) | 1,6-disubstituované izochromany pro léčbu bolestí hlavy při migréně | |
| JP5189110B2 (ja) | ドーパミンｄ４受容体拮抗剤であるピペラジニル−プロピル−ピラゾール誘導体及びそれを含む医薬組成物 | |
| US20020103205A1 (en) | Muscarinic antagonists | |
| US20030153507A1 (en) | HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis | |
| JPWO2005037269A1 (ja) | 新規ピペリジン誘導体 | |
| HU211336A9 (en) | Heterocyclic derivatives | |
| AU684874B2 (en) | Heterocyclic compounds for the treatment of cns and cardiovascular disorders | |
| JP2001525406A (ja) | 新規な化合物 | |
| WO2007042660A2 (fr) | Dérivés de la 1-amino-phtalazine substituee, leur préparation et leur application en thérapeutique | |
| JP2015524481A (ja) | （ｓ）−３−（４−（（４−（モルホリノメチル）ベンジル）オキシ）−１−オキソイソインドリン−２−イル）ピペリジン−２，６−ジオン及びその医薬として許容し得る形態の製造プロセス | |
| JP2006527769A (ja) | Ｃｂ１モジュレーターとしての２，３位置換５，６−ジアリール−ピラジン誘導体 | |
| AU2021410119A1 (en) | Tetrahydroquinoline derivative and medicinal use thereof | |
| JP3035356B2 (ja) | ピロリジニルヒドロキサム酸化合物及びその製造方法 | |
| HU225747B1 (en) | New benzenesulphonamide compounds, their preparation thereof and pharmaceutical compositions containing them | |
| US20040034036A1 (en) | N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-piperazin-1-yl-benzenesulfonamide | |
| KR20150065190A (ko) | 피라진 유도체 | |
| OA11235A (en) | Quatenary ammonium compounds as tachykinin antagonists | |
| MXPA04012345A (es) | Derivados de pirimidina 2,5-substituida como antagonistas ix del receptor ccr-3. | |
| AU707950B2 (en) | Heterocyclic compounds for treating myocardial ischemia | |
| JPH06306025A (ja) | ジアリールアルカン誘導体 | |
| KR19990028550A (ko) | 편두통 치료용의 1,6-이치환된 이소크로만 | |
| KR940009533B1 (ko) | 헥사하이드로디벤조디옥산에서 유도된 암모늄염의 제조방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PD00 | Pending as of 2000-06-30 in czech republic |