CZ20031981A3 - Bone implant, in particular, an inter-vertebral implant - Google Patents

Bone implant, in particular, an inter-vertebral implant Download PDF

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Publication number
CZ20031981A3
CZ20031981A3 CZ20031981A CZ20031981A CZ20031981A3 CZ 20031981 A3 CZ20031981 A3 CZ 20031981A3 CZ 20031981 A CZ20031981 A CZ 20031981A CZ 20031981 A CZ20031981 A CZ 20031981A CZ 20031981 A3 CZ20031981 A3 CZ 20031981A3
Authority
CZ
Czechia
Prior art keywords
bone implant
characterized
implant according
bone
hollow body
Prior art date
Application number
CZ20031981A
Other languages
Czech (cs)
Inventor
Mathysárobertájr
Lechmannábeat
Gasserábeat
Original Assignee
Synthesáagáchur
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthesáagáchur filed Critical Synthesáagáchur
Priority to PCT/CH2001/000069 priority Critical patent/WO2002060356A1/en
Publication of CZ20031981A3 publication Critical patent/CZ20031981A3/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2/30965Reinforcing the prosthesis by embedding particles or fibres during moulding or dipping
    • AHUMAN NECESSITIES
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • AHUMAN NECESSITIES
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2835Bone graft implants for filling a bony defect or an endoprosthesis cavity
    • AHUMAN NECESSITIES
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/3008Properties of materials and coating materials radio-opaque, e.g. radio-opaque markers
    • AHUMAN NECESSITIES
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
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    • A61F2/30771Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30772Apertures or holes, e.g. of circular cross section
    • A61F2002/30777Oblong apertures
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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30772Apertures or holes, e.g. of circular cross section
    • A61F2002/30784Plurality of holes
    • A61F2002/30785Plurality of holes parallel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30772Apertures or holes, e.g. of circular cross section
    • A61F2002/30784Plurality of holes
    • A61F2002/30789Plurality of holes perpendicular with respect to each other
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/30767Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth
    • A61F2/30771Special external or bone-contacting surfaces, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30841Sharp anchoring protrusions for impaction into the bone, e.g. sharp pins, spikes
    • A61F2002/30843Pyramidally-shaped
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/3094Designing or manufacturing processes
    • A61F2/30942Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • A61F2002/30957Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques using a positive or a negative model, e.g. moulds
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2002/4475Joints for the spine, e.g. vertebrae, spinal discs hollow
    • AHUMAN NECESSITIES
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0096Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
    • A61F2250/0098Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
    • AHUMAN NECESSITIES
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures
    • A61F2310/00185Ceramics or ceramic-like structures based on metal oxides
    • A61F2310/00239Ceramics or ceramic-like structures based on metal oxides containing zirconia or zirconium oxide ZrO2
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
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    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00179Ceramics or ceramic-like structures
    • A61F2310/00293Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389The prosthesis being coated or covered with a particular material
    • A61F2310/00395Coating or prosthesis-covering structure made of metals or of alloys
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    • AHUMAN NECESSITIES
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    • A61F2310/00395Coating or prosthesis-covering structure made of metals or of alloys
    • A61F2310/00419Other metals
    • A61F2310/00562Coating made of platinum or Pt-based alloys
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    • A61F2310/00395Coating or prosthesis-covering structure made of metals or of alloys
    • A61F2310/00419Other metals
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    • A61F2310/00592Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00796Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite

Abstract

The inter-vertebral implant is made from a radiation-transparent material and embodied as an annular hollow body (1). Said implant comprises a sleeve (6) in the form of a hollow cylindrical section, comprising a front (9), a rear (10) and two lateral sections (11) and defines a cylindrical axis (7). The hollow body (1) is divided by two intermediate walls (3), running essentially parallel to the cylinder axis (7) and connecting the front section (9) with the rear section (10) of the sleeve. The surface (2) of the bone implant comprises a surface roughness of at least 2 mu m. This surface roughness permits the newly growing bone a better fixation to the implant, in other words a better bone integration.

Description

Technical field

The invention relates to a bone implant, in particular an intervertebral implant as defined in claim 1 as well as a method for producing a bone implant as defined in claim 16.

BACKGROUND OF THE INVENTION

Such a bone implant is known from FR-A-2 703 580 ROBERT. The disadvantages of this known intervertebral implant are that

(A) the smooth surface of the cover and base implant surfaces provided with coarse scratches that come into contact with the end plates of the adjacent vertebral body do not cause any optimal uptake of bone tissue, and that

B) When filling material is used in the concave space of the implant, this material may easily fall out due to smooth inner walls.

The foregoing discussion of the prior art is merely an explanation of the invention and does not mean that the cited prior art at the time of this filing or its priority was also actually published or publicly known.

SUMMARY OF THE INVENTION

Here the invention seeks to remedy. It is an object of the present invention to provide a bone implant, in particular an intervertebral implant, which has an optimal surface structure for bone tissue acceptance.

The invention solves the problem by a bone implant having the features of claim 1 and by a method having the features of claim 16.

• · · · · ·

The surface roughness of at least 2 µm according to the invention allows the newly grown bone to be better anchored to the implant, ie better bone integration.

An advantageous further development is that the hollow body is divided by at least two partitions, the partitions being reinforced together preferably by means of transverse walls. These baffles increase the surface area to the adjacent end plates of the vertebral body, thereby reducing planar pressure and preventing the implant from burying into the adjacent vertebral body. For this purpose, they allow hollow spaces lying between the implant growth through the bone structure.

A preferred embodiment is that the surface roughness is less than 10 µm. Too much surface roughness weakens the remaining tips, which can in turn lead to osteolysis and thus reduce arthrodesis.

An advantageous further development is that the partitions are provided with perforations which preferably have a smallest area of 3.5 mm 2 . Perforation of the side walls serves for spatial anchoring of the newly grown bone structure and also for primary insertion of the filler.

An advantageous further development is that the lateral sections of the hollow body shell have perforations which preferably have a minimum area of 3.5 mm 2 . The perforations of the lateral sections of the sheath serve to anchor the newly grown bone structure and primarily to hold the implant during implant placement.

A preferred embodiment is that the radiation transmissive material is selected from the following group:

polyaryl ether ketone (PAEK), polyetherimide (PEI), polyoxymethylene (POM), liquid crystal polymer (LCP), polymethylpentene (PMP), polysulfone (PSU), polyethersulfone (PESU or PES) , polyethylene terephthalate (PETP), polymethyl methacrylate (PMMA), and ultra-high molecular weight polyethylene (UHMW-PE).

All of these materials are elastic, but have different mechanical properties, such as elasticity (rigidity) and strength. In comparison with other polymers, they exhibit partially favorable creep properties or low water uptake. This allows optimum selection according to the application needs.

A preferred embodiment is that the radiation-transmissive material is reinforced with fibers, preferably carbon fibers or PEEK fibers. The fiber reinforcement of the radiation transmissive material will generally strengthen or achieve the mechanical properties.

A preferred embodiment is that the V: v ratio between the total volume V of the bone implant and the volume in the concave body is in the range 1.9 to 2.3. This ratio has been shown to combine the advantages of a mechanically stable implant with the maximum volume of a newly grown bone structure.

An advantageous further embodiment consists in that the surface of the implant is at least partially coated with an X-ray transmission or a thin layer which does not affect the X-ray transmission. The advantage of the X-ray transparent coating ensures the possibility of observation during an increase in arthrodesis. While pure PEEK is characterized by excellent biocompatibility, an additional coating of suitable material enhances the mechanical properties and interface between the newly grown bone and the implant. Suitable coating materials are preferably very low density metals which do not substantially affect the transmission of X-rays. Titanium, gold or platinum or other suitable implant metals are particularly suitable.

A preferred embodiment is that the coating consists of a ceramic, preferably of hydroxylapatite or calcium phosphate. Both ceramics, hydroxylapatite and calcium phosphate, which are suitable as coatings, are characterized by the advantage that they are fully integrated into the bone or even replaced by new natural bone tissue.

A preferred embodiment is that the hollow body is filled at least partially with a calcium phosphate filler, preferably hydroxylapatite or calcium phosphate. This provides better, undisturbed arthrodesis control. The hollow body may also be filled with calcium sulfate filler, demineralized bone, autologous bone or coral material.

A preferred embodiment consists in that the hollow body (1) is filled at least partially with an X-ray opaque filler of a resorbable, preferably porous polymer. To make the filler X-ray opaque, a contrast agent is added to the polymer. For PLA, for example, a marker (highlighter) such as zirconia can be added, and barium sulfate can be added to PEEK.

An advantageous further development is that the perforations possibly occurring in the implant are at least partially filled with an X-ray opaque filler. This prevents the filler from falling out.

• ·

The method for producing a bone implant according to the invention consists in producing a circular hollow body by injection molding, thermoforming or thermoforming. By thermoforming, the polymer is compressed in all shaped elements, which is characterized by a particularly better fatigue strength

The invention and a further embodiment of the invention are explained in more detail as follows, based on a partially schematic illustration of an exemplary embodiment.

It shows:

Giant. 1 is a perspective view of an intervertebral implant according to the invention;

Giant. 2 is a top view of the implant of FIG. 1;

Giant. 3 is an elevational view of the implant of FIG. 1;

Giant. 4 is a side view of the implant of FIG. 1.

The intervertebral implant shown in Figures 1 to 4 consists of a radiation-permeable material (PEEK, which may optionally be reinforced with carbon fibers or glass fibers), which is formed as a circular hollow body 1 by injection molding. It comprises a concave cylindrical section (6) having a front section (9), a rear section (10) and two lateral sections (11) as well as defining an axis of the cylinder (7).

The hollow body (1) is connected by two baffles (3) which extend substantially parallel to the axis of the cylinder (7) and the front section (9) with the rear section (10) of the housing so that it is divided into cavities. The two partitions (3) are reinforced together by a transverse stiffener (4). The partitions (3) are provided with perforations (5) having an area of approximately 10 mm 2 . Also, the side sections (11) of the housing (6) have perforations (8) having an area of approximately 10 mm 2 .

The bone implant surface (2) has a surface roughness of 6 μτη and is provided with a thin coating of gold that transmits X-rays.

The V: v ratio between the total volume of bone implant V and the volume in the hollow body is 2.1.

The hollow body (1) can be filled with an X-ray opaque filler of hydroxylapaptite, taking into account that the perforations (5; 8) are also filled with an X-ray opaque filler. AND

4 · 4 ·

Claims (16)

  1. PATENT CLAIMS
    A bone implant, in particular an intervertebral implant, which consists of a radiation-transmitting material and is formed as a circular hollow body (1) with a shell (6) of concave cylindrical shape comprising a front section (9), a rear section (10) and two side sections (11) as well as defining an axis of the cylinder (7), characterized in that:
    A) the hollow body (1) is divided by at least two partitions (3) which extend substantially parallel to the axis of the cylinder (7) and connect the front section (9) to the rear section (10) of the housing; and
    B) the surface (2) of the bone implant has a surface roughness of at least pm.
  2. Bone implant according to claim 1, characterized in that the baffles (3) are reinforced together by a transverse reinforcement (4).
  3. Bone implant according to claim 1 or 2, characterized in that the surface roughness is less than 10 µm.
  4. Bone implant according to one of Claims 1 to 3, characterized in that the partitions (3) are provided with perforations (5) which preferably have a smallest area of 3.5 mm 2 .
  5. Bone implant according to one of Claims 1 to 4, characterized in that the lateral sections (11) of the sheath (6) have perforations (8) which preferably have a smallest area of 3.5 mm 2 .
  6. Bone implant according to any one of claims 1 to 5, characterized in that the radiation transmissive material is selected from the following group: polyaryl ether ketone (PAEK), polyetherimide (PEI), polyoxymethylene (POM), liquid crystal polymer (LCP), polymethylpentene ( PMP), polysulfone (PSU), polyethersulfone (PESU or PES), * polyethylene terephthalate (ΡΕΤΡ), polymethyl methacrylate (ΡΜΜΑ) and ultra high molecular weight polyethylene (UHMW-PE).
  7. Bone implant according to one of Claims 1 to 6, characterized in that the radiation-transmitting material is reinforced with fibers, preferably carbon fibers, glass fibers or PEEK fibers.
  8. Bone implant according to any one of claims 1 to 7, characterized in that the V: ratio is between the total volume
    In the bone implant and the volume in the hollow body (1) lies in the range 1.9 to 2.3.
  9. Bone implant according to any one of claims 1 to 8, characterized in that the surface is at least partially coated with an X-ray transmitting coating or a thin layer which has little influence on the X-ray transmittance.
  10. Bone implant according to claim 9, characterized in that the coating consists of a metal, preferably of titanium, gold or platinum.
  11. Bone implant according to claim 9, characterized in that the coating consists of a ceramic substance, preferably hydroxylapatite or calcium phosphate.
  12. Bone implant according to one of Claims 1 to 11, characterized in that the hollow body (1) is a calcium phosphate filler, preferably hydroxylapatite or calcium phosphate.
  13. Bone implant according to one of Claims 1 to 11, characterized in that the hollow body (1) is filled with at least one of the following: Partially filled with calcium sulphate, demineralized bone, autologous bone or coral substances.
  14. Bone implant according to one of Claims 1 to 11, characterized in that the hollow body (1) is filled at least partially with a filler of a resorbable, preferably porous polymer.
    • · ·· ·
  15. Bone implant according to any one of claims 4 to 14, characterized in that the perforations (5; 8) possibly occurring are at least partially filled with an X-ray opaque filler.
  16. A method for producing a bone implant according to any one of claims 1 to 15, characterized in that a circular hollow body (1) is produced by injection molding, thermoforming or thermoforming.
    B * 4 · 4 · A · A · t · V V V V V V V V V V V V V V V V V ; υΰυΛ, '
    1/1
    v. 4
CZ20031981A 2001-01-30 2001-01-30 Bone implant, in particular, an inter-vertebral implant CZ20031981A3 (en)

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