CU24121B1 - Vesículas que comprenden factor de crecimiento epidérmico y composiciones que las contienen - Google Patents
Vesículas que comprenden factor de crecimiento epidérmico y composiciones que las contienenInfo
- Publication number
- CU24121B1 CU24121B1 CUP2012000112A CU20120112A CU24121B1 CU 24121 B1 CU24121 B1 CU 24121B1 CU P2012000112 A CUP2012000112 A CU P2012000112A CU 20120112 A CU20120112 A CU 20120112A CU 24121 B1 CU24121 B1 CU 24121B1
- Authority
- CU
- Cuba
- Prior art keywords
- vesicles
- growth factor
- epidermal growth
- compositions containing
- include epidermal
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1808—Epidermal growth factor [EGF] urogastrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/14—Liposomes; Vesicles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
- A61K8/416—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
- A61L26/0066—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Birds (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Diabetes (AREA)
- Materials Engineering (AREA)
- Physical Education & Sports Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
Abstract
La invención se refiere a vesículas que comprenden el Factor de Crecimiento Epidérmico (EGF), un surfactante catiónico, y colesterol o sus derivados. La invención también revela un procedimiento para su preparación, basado en la tecnología de fluidos comprimidos (FCs). Las vesículas de la invención tienen utilidad en la fabricación de medicamentos y productos cosméticos, y en la ingeniería tisular.
Priority Applications (28)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CUP2012000112A CU24121B1 (es) | 2012-08-02 | 2012-08-02 | Vesículas que comprenden factor de crecimiento epidérmico y composiciones que las contienen |
UAA201501774A UA113448C2 (xx) | 2012-08-02 | 2013-02-08 | Везикули, які містять епідермальний фактор росту і його композиції |
ARP130102727A AR091951A1 (es) | 2012-08-02 | 2013-08-01 | Vesiculas que comprenden factor de crecimiento epidermico y composiciones que las contienen |
DK13759116.0T DK2915541T3 (en) | 2012-08-02 | 2013-08-02 | VESICLES INCLUDING EPIDERMAL GROWTH FACTOR AND COMPOSITIONS CONTAINING SAME |
EP13759116.0A EP2915541B1 (en) | 2012-08-02 | 2013-08-02 | Vesicles which include epidermal growth factor and compositions that contain same |
SG11201500797SA SG11201500797SA (en) | 2012-08-02 | 2013-08-02 | Vesicles which include epidermal growth factor and compositions that contain same |
CN201380048721.3A CN104684575B (zh) | 2012-08-02 | 2013-08-02 | 包含表皮生长因子的囊泡和含有所述囊泡的组合物 |
SI201330504A SI2915541T1 (sl) | 2012-08-02 | 2013-08-02 | Vezikli, ki vključujejo epidermalni rastni faktor in sestave, ki le-tega vsebujejo |
MX2015001561A MX360674B (es) | 2012-08-02 | 2013-08-02 | Vesiculas que comprenden factor de crecimiento epidermico y composiciones que las contienen. |
US14/418,511 US9717776B2 (en) | 2012-08-02 | 2013-08-02 | Vesicles comprising epidermal growth factor and compositions thereof |
AU2013299036A AU2013299036C1 (en) | 2012-08-02 | 2013-08-02 | Vesicles which include epidermal growth factor and compositions that contain same |
BR112015002103-4A BR112015002103B1 (pt) | 2012-08-02 | 2013-08-02 | Vesícula, processo para a preparação de vesículas, composição farmacêutica, uso de uma vesícula, e, produto cosmético |
RS20170122A RS55713B1 (sr) | 2012-08-02 | 2013-08-02 | Vezikule koje obuhvataju epidermalni faktor rasta i supstance koje isti sadrže |
CA2880404A CA2880404C (en) | 2012-08-02 | 2013-08-02 | Vesicles comprising epidermal growth factor and compositions thereof |
MYPI2015700300A MY196771A (en) | 2012-08-02 | 2013-08-02 | Vesicles which include epidermal growth factor and compositions that contain same |
ES13759116.0T ES2613087T3 (es) | 2012-08-02 | 2013-08-02 | Vesículas que comprenden factor de crecimiento epidérmico y composiciones que las contienen |
PCT/CU2013/000004 WO2014019555A1 (es) | 2012-08-02 | 2013-08-02 | Vesiculas que comprenden factor de crecimiento epidermico y composiciones que las contienen |
RU2015106683A RU2649781C2 (ru) | 2012-08-02 | 2013-08-02 | Везикулы, содержащие эпидермальный фактор роста и его композиции |
PT137591160T PT2915541T (pt) | 2012-08-02 | 2013-08-02 | Vesículas que incluem fator de crescimento epidérmico e composições que contêm o mesmo |
HUE13759116A HUE033286T2 (en) | 2012-08-02 | 2013-08-02 | Vesicles containing epidermal growth factor and preparations containing them |
KR1020157005385A KR101752757B1 (ko) | 2012-08-02 | 2013-08-02 | 상피 성장 인자를 포함하는 소포체 및 이를 포함하는 조성물 |
JP2015524635A JP6251740B2 (ja) | 2012-08-02 | 2013-08-02 | 上皮増殖因子を含む小胞及びその組成物 |
PL13759116T PL2915541T3 (pl) | 2012-08-02 | 2013-08-02 | Pęcherzyki zawierające nabłonkowy czynnik wzrostu i kompozycje je zawierające |
CL2015000254A CL2015000254A1 (es) | 2012-08-02 | 2015-02-02 | Vesículas que comprenden factor de crecimiento epidermico (egf); proceso de preparación; composición farmacéutica que las comprende; y uso para tratar heridas complejas . |
ZA2015/00763A ZA201500763B (en) | 2012-08-02 | 2015-02-02 | Vesicles which include epidermal growth factor and compositions that contain same |
HK15111950.8A HK1210970A1 (en) | 2012-08-02 | 2015-12-03 | Vesicles which include epidermal growth factor and compositions that contain same |
HRP20170145TT HRP20170145T1 (hr) | 2012-08-02 | 2017-01-30 | Čestice koje sadrže epidermalni faktor rasta i supstancije koje sadrže isti |
US15/664,548 US11510965B2 (en) | 2012-08-02 | 2017-07-31 | Vesicles comprising epidermal growth factor and compositions thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CUP2012000112A CU24121B1 (es) | 2012-08-02 | 2012-08-02 | Vesículas que comprenden factor de crecimiento epidérmico y composiciones que las contienen |
Publications (2)
Publication Number | Publication Date |
---|---|
CU20120112A7 CU20120112A7 (es) | 2014-03-26 |
CU24121B1 true CU24121B1 (es) | 2015-08-27 |
Family
ID=49118249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CUP2012000112A CU24121B1 (es) | 2012-08-02 | 2012-08-02 | Vesículas que comprenden factor de crecimiento epidérmico y composiciones que las contienen |
Country Status (27)
Country | Link |
---|---|
US (2) | US9717776B2 (es) |
EP (1) | EP2915541B1 (es) |
JP (1) | JP6251740B2 (es) |
KR (1) | KR101752757B1 (es) |
CN (1) | CN104684575B (es) |
AR (1) | AR091951A1 (es) |
AU (1) | AU2013299036C1 (es) |
BR (1) | BR112015002103B1 (es) |
CA (1) | CA2880404C (es) |
CL (1) | CL2015000254A1 (es) |
CU (1) | CU24121B1 (es) |
DK (1) | DK2915541T3 (es) |
ES (1) | ES2613087T3 (es) |
HK (1) | HK1210970A1 (es) |
HR (1) | HRP20170145T1 (es) |
HU (1) | HUE033286T2 (es) |
MX (1) | MX360674B (es) |
MY (1) | MY196771A (es) |
PL (1) | PL2915541T3 (es) |
PT (1) | PT2915541T (es) |
RS (1) | RS55713B1 (es) |
RU (1) | RU2649781C2 (es) |
SG (1) | SG11201500797SA (es) |
SI (1) | SI2915541T1 (es) |
UA (1) | UA113448C2 (es) |
WO (1) | WO2014019555A1 (es) |
ZA (1) | ZA201500763B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101739208B1 (ko) * | 2014-12-30 | 2017-05-25 | (주)셀트리온 | 표피성장인자와 리포좀의 하이브리드형 다중층 나노구조체 및 그 제조방법 |
US20180042847A1 (en) * | 2015-03-16 | 2018-02-15 | Duncan ROSS | Method of treatment comprising membrane-enclosed vesicle |
CN108699519A (zh) * | 2016-01-12 | 2018-10-23 | 康干细胞生物技术有限公司 | 干细胞衍生的含有大量生长因子的外来体 |
WO2017147407A1 (en) | 2016-02-25 | 2017-08-31 | Board Of Regents, The University Of Texas System | Compositions comprising composite nanocarriers and methods of making and uses thereof |
US11241480B2 (en) * | 2017-01-26 | 2022-02-08 | Washington University | Methods for modulation of dietary and microbial exposure with compositions comprising an EGFR ligand |
TWI636794B (zh) * | 2017-11-06 | 2018-10-01 | 吳治增 | 一種奈米複合材料及其應用 |
CU20190022A7 (es) * | 2019-03-18 | 2020-10-20 | Centro De Ingenieria Genetica Y Biotecnologia Biocubafarma | Composición farmacéutica para el tratamiento de la úlcera del pie diabético |
WO2021206328A1 (ko) * | 2020-04-10 | 2021-10-14 | 한국과학기술연구원 | 신규 재조합 엑소좀 및 그의 용도 |
CN113827622B (zh) * | 2021-08-31 | 2023-11-07 | 南方医科大学 | 奇异变形杆菌外膜囊泡在制备预防或治疗骨溶解性疾病药物中的应用 |
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JPH0272123A (ja) * | 1988-09-07 | 1990-03-12 | Hitachi Chem Co Ltd | ヒト上皮細胞成長因子の投与方法及びヒト上皮細胞成長因子含有疾病治療剤 |
US4944948A (en) | 1989-02-24 | 1990-07-31 | Liposome Technology, Inc. | EGF/Liposome gel composition and method |
US5064655A (en) * | 1989-02-24 | 1991-11-12 | Liposome Technology, Inc. | Liposome gel composition and method |
US5618544A (en) | 1992-08-12 | 1997-04-08 | Bays-Brown Dermatologics, Inc. | Method of decreasing cutaneous senescence |
US20020081324A1 (en) * | 2002-01-22 | 2002-06-27 | Twine Rebecca Wright | Method of treating aging skin and wrinkles using a combination of growth factors that is commercially prepared or derived from one's own blood |
AU2003222668A1 (en) * | 2002-04-25 | 2003-11-10 | Rapidheal, Inc. | Growth factor delivery system for the healing of wounds and the prevention of inflammation and disease |
ES2265262B1 (es) | 2005-01-31 | 2008-03-01 | Activery Biotech, S.L.(Titular Al 50%) | Procedimiento para la obtencion de sistemas micro- y nanodispersos. |
WO2007065464A1 (en) | 2005-12-09 | 2007-06-14 | Stichting Katholieke Universiteit | Epidermal growth factor (egf) derivatives with selectable selectivity for the erb receptor family |
CU23411B6 (es) * | 2005-12-29 | 2009-09-08 | Ct Ingenieria Genetica Biotech | Uso tópico del factor de crecimiento epidérmico en liposomas para prevenir la amputación del pie diabético |
JP2009234945A (ja) * | 2008-03-26 | 2009-10-15 | Shalom:Kk | h−EGF含有スフィンゴミエリンリポソームおよびこれを配合した化粧料及び医薬品 |
CN102091034A (zh) * | 2009-12-15 | 2011-06-15 | 哈尔滨工业大学 | 基于胆固醇衍生物的有机-无机复合纳米囊泡的制备 |
KR101102834B1 (ko) * | 2010-02-24 | 2012-01-05 | 충남대학교산학협력단 | 신규한 리포좀 제조 방법 및 장치 |
WO2011138687A2 (en) * | 2010-05-06 | 2011-11-10 | Regenics As | Use of cellular extracts for skin rejuvenation |
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