CO6470796A2 - Forma de dosificación de liberación controlada extruída por fusión en caliente - Google Patents

Forma de dosificación de liberación controlada extruída por fusión en caliente

Info

Publication number
CO6470796A2
CO6470796A2 CO11159505A CO11159505A CO6470796A2 CO 6470796 A2 CO6470796 A2 CO 6470796A2 CO 11159505 A CO11159505 A CO 11159505A CO 11159505 A CO11159505 A CO 11159505A CO 6470796 A2 CO6470796 A2 CO 6470796A2
Authority
CO
Colombia
Prior art keywords
extension
dosage form
controlled release
longitudinal direction
face
Prior art date
Application number
CO11159505A
Other languages
English (en)
Inventor
Lutz Barnscheid
Eric Galia
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42332474&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6470796(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of CO6470796A2 publication Critical patent/CO6470796A2/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Esta invención se relaciona con un comprimido farmacéutico extruído en caliente con liberación controlada de un ingrediente farmacológicamente activo (A) incluida en una matriz que comprende un polímero (C). presentando el comprimido una forma oblonga que comprende una dirección longitudinal de extensión, una dirección transversal de extensión ortogonal a la dirección longitudinal de extensión, una cara frontal, una cara posterior opuesta y un borde circunferencial entre dichas cara frontal y posterior, en la que: el núcleo del comprimido farmacéutico presenta una orientación morfológica causada por la extrusión en caliente que es sustancialmente ortogonal respecto a la dirección longitudinal de extensión de la forma de dosificación, y/o la liberación por unidad de área del ingrediente farmacológicamente activo (A) a través de la cara frontal y de la cara posterior opuesta es más rápida que la liberación a partir del borde circunferencial.
CO11159505A 2009-07-22 2011-11-22 Forma de dosificación de liberación controlada extruída por fusión en caliente CO6470796A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP09009499 2009-07-22

Publications (1)

Publication Number Publication Date
CO6470796A2 true CO6470796A2 (es) 2012-06-29

Family

ID=42332474

Family Applications (1)

Application Number Title Priority Date Filing Date
CO11159505A CO6470796A2 (es) 2009-07-22 2011-11-22 Forma de dosificación de liberación controlada extruída por fusión en caliente

Country Status (23)

Country Link
US (1) US10080721B2 (es)
EP (1) EP2456427B1 (es)
JP (1) JP5667183B2 (es)
KR (1) KR101738369B1 (es)
CN (1) CN102573805A (es)
AR (1) AR077493A1 (es)
AU (1) AU2010275753B2 (es)
BR (1) BR112012001547A2 (es)
CA (1) CA2765971C (es)
CL (1) CL2011002968A1 (es)
CO (1) CO6470796A2 (es)
EC (1) ECSP12011597A (es)
ES (1) ES2534908T3 (es)
HK (1) HK1167811A1 (es)
IL (1) IL216526A (es)
MX (1) MX2012000317A (es)
NZ (1) NZ596667A (es)
PE (1) PE20121067A1 (es)
PL (1) PL2456427T3 (es)
RU (1) RU2547555C2 (es)
TW (1) TW201105316A (es)
WO (1) WO2011009602A1 (es)
ZA (1) ZA201109445B (es)

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