CN2691489Y - Multiple wave-length near-infrared instrument for testing blood-oxygen content in brain tissue - Google Patents

Multiple wave-length near-infrared instrument for testing blood-oxygen content in brain tissue Download PDF

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CN2691489Y
CN2691489Y CN 200320125532 CN200320125532U CN2691489Y CN 2691489 Y CN2691489 Y CN 2691489Y CN 200320125532 CN200320125532 CN 200320125532 CN 200320125532 U CN200320125532 U CN 200320125532U CN 2691489 Y CN2691489 Y CN 2691489Y
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circuit
operational amplifier
brain tissue
connected
resistance
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CN 200320125532
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谢则平
李凯扬
秦钊
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武汉一海数字工程有限公司
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Abstract

The utility model discloses a multiple wave-length near-infrared instrument for testing blood-oxygen content in brain tissue, which is composed of a light source part and a test part containing a photoelectric conversion circuit and a transmittal circuit. The light source part is provided with a pulse generating circuit and a lamp driving circuit, and the output of the pulse generating circuit is connected to the lamp driving circuit; in the detection part, the photoelectric conversion circuit is provided with two sets of or more than two sets of photodiodes and the corresponding primary transmittals; a filter which can detect different monochromatic lights is arranged on each photodiode, and a trap circuit is connected between the photoelectric conversion circuit and the transmittal circuit. The back part of the test part is provided with a data-processing part formed from the sequential connection of an interface sampling circuit, a digital-analogue conversion chip, and a monolithic computer controlled system. The input of the interface sampling circuit is connected to the transmittal circuit of the test part. The utility model can directly make a remote or a real-time test and treatment to the blood-oxygen content in the patient's brain tissue. The accuracy rate is high, the volume is small, and the use is easy.

Description

多波长近红外脑组织血氧含量检测仪 Multi-wavelength near-infrared brain blood oxygen content tester

技术领域 FIELD

本实用新型涉及一种监护脑组织血、氧含量的仪器,尤其是以物理的光学方法无创监测脑组织血、氧含量的检测仪。 The present invention relates to a method for monitoring cerebral blood oxygen content of instruments, especially in non-invasive optical methods physical monitoring cerebral blood, oxygen content detector.

背景技术 Background technique

目前,脑组织血、氧含量检测仪依据原理不同,有各种不同类型的产品,近红外线分光光度无创伤测定技术研制的仪器是其中最广泛使用的一种,如美国的RunMan仪等,但现有技术使用的脑组织血、氧含量检测仪无信号存储和纪录的功能、检测数据需要配备描迹器描记显示,而且须另配置模数A/D转换外接计算机分析数据,其功能受限且附件庞大移动不便。 Currently, brain blood oxygen content detector based on different principles, there are a variety of different types of products, non-invasive near-infrared spectrophotometric measurement techniques developed instrument is one of the most widely used, such as the US RunMan instrument, but cerebral blood used in the prior art, the oxygen content of the function detector and no signal stored in the record, the data need to be equipped detected tracings trace is displayed, and the other to be arranged modulus a / D converting an external computer data analysis, its function is limited and mobile accessory huge inconvenience.

实用新型内容本实用新型的目的是要提供一种多波长近红外脑组织血、氧含量检测仪,能够远程、实时检测同时存贮、打印、报告病人脑组织血、氧含量,并且体积小方便移动。 SUMMARY The object of the present invention is to provide a multi-wavelength near-infrared cerebral blood oxygen content detector, remotely, real-time detection while stored, printed, patient reporting cerebral blood oxygen content, small size and easy to mobile.

为了达到上述目的,本实用新型在现有由光源部分和包含光电转换电路、运放电路的检测部分构成的多波长近红外脑组织血氧含量检测仪基础上做了以下改进:1)光源部分设有脉冲发生电路与灯驱动电路,脉冲发生电路的输出端连接到灯驱动电路;2)检测部分包含在光电转换电路设置的两组到五组光电二极管及相应初级运放,在光电二极管表面加装通透不同波长光的滤光片,光电转换电路和运放电路之间添接陷波电路;3)在检测部分后添加数据处理部分,该部分由采样接口电路、数模转换电路、单片机系统顺次连接构成,检测电路中的运放电路输出到采样接口电路。 To achieve the above object, the present invention, the oxygen content in the existing multi-wavelength detector composed of a light source section and detection section includes a photoelectric conversion circuit, the operational amplifier circuit on the near-infrared brain made the following improvements: 1) a light source section pulse generating circuit is provided with a lamp driving circuit, the output terminal of the pulse generating circuit connected to the lamp driving circuit; 2) detecting section included in the two to five set of photodiodes and the photoelectric converting circuit is provided corresponding to the primary operational amplifier, the photodiode surface installation of different wavelengths of light permeable filter, spliced ​​between the photoelectric conversion circuit and a trap circuit operational amplifier circuit; 3) adding the detection data processing section in the portion which the interface circuit by the sampling, digital to analog conversion circuit, SCM system configuration are sequentially connected, the output of the detection circuit operational amplifier circuit to the sampling interface circuit.

而且,光源部分的脉冲发生电路包括运算放大器U4B、二极管D3、D4和电阻R6、R7、R8、R9、R10以及电容C3,二极管D3、D4和电阻R6并联后和电容C3、电阻R7串联组成积分器反馈到运算放大器U4B的反相端,电阻R8、R9、R10串联组成正反馈;光源部分的灯驱动电路包括运算放大器U4A和达林顿管Q1、电阻R11、R12、R13、R14、R15、R16、R17、开关S、灯泡G,开关S的两个触点S1、S2分别接电阻R13和电阻R14,电阻R11、R12、R13、R14相互并联后接到运算放大器U4A的正相端,达林顿管Q的发射极上电阻R16、R17相互串联后和灯泡G并联,运算放大器U4A的反相端接在电阻R16、R17之间。 Further, the pulse light source section generating circuit includes an operational amplifier U4B, diodes D3, D4 and resistors R6, R7, R8, R9, R10 and a capacitor C3, diode D3, D4 and resistor R6 rear parallel and a capacitor C3, a resistor R7 in series integrator feedback to the inverting input of the operational amplifier U4B, resistors R8, R9, R10 in series positive feedback; source lamp driving circuit portion comprises an operational amplifier U4A and Darlington Q1, resistors R11, R12, R13, R14, R15, two contacts S1 R16, R17, switch S, lamp G, switch S, S2 are respectively connected to resistors R13 and resistor R14, to the resistor of the operational amplifier U4A R11, R12, R13, R14 connected in parallel with the positive terminal of Linton transistor Q emission electrode resistor R16, the resistor R17 in series with each other R16, R17 connected in parallel between the G and the lamp, the operational amplifier U4A inverting termination.

而且,光电转换电路中每个光电二极管的相应初级运放是由运算放大器和与光电二极管串联的电阻组成的放大器,各个放大器的反馈电阻之间串联平衡调节电路;陷波电路采用有源双T网络的后面加运算放大器构成的有源双T带阻滤波器,每组光电二机管的相应初级运放后配两个同样的有源双T带阻滤波器。 Further, the photoelectric conversion circuit corresponding to each photodiode of the primary operational amplifier by the amplifier is an operational amplifier and a resistor in series with the photodiode composed of a series feedback resistor between each amplifier balance adjustment circuit; notch circuit using active double-T the active double-T bandstop filter network is added back operational amplifier, the respective primary put into operation with the same two active double-T bandstop filter tubes each photodiode machine.

而且,数据处理部分的采样接口电路由8选1的模拟开关U6和运算放大器U7构成的跟随器组成;数据处理部分的单片机系统采用锁存器U9和编码器U10作为单片机U11和数模转换芯片U8间的采样控制,单片机系统包含内置的显示器、键盘、描迹器、存储器和打印机。 Further, the interface circuit sampling by the data processing section 8 is selected from the follower analog switch U6 and U7 operational amplifier 1 is constituted with; SCM system using a data processing section and the encoder latches U9 U10 U11 as a digital to analog converter chip microcontroller sampling control, U8 between SCM system comprising built-in monitor, a keyboard, a trace, a memory and printer.

采用这样的电路结构后,多波长近红外脑组织血、氧含量监护仪无需附加设备,能够直接转换光电模拟信号为数字信号并进行各种数据处理,准确率提高且使用方便。 With such a circuit configuration, a multi-wavelength near-infrared blood brain tissue, monitor oxygen content without additional apparatus, can be directly photoelectrically converted analog signals into digital signals and performs various data processing, improve the accuracy and ease of use.

附图说明 BRIEF DESCRIPTION

图1本实用新型结构框图;图2光源部分电路图;图3检测部分电路图;图4数据处理部分电路图。 A block diagram invention; Figure 2 a circuit diagram of a light source portion; FIG. 3 a circuit diagram of the detection section; FIG. 4 a circuit diagram of a data processing section.

具体实施方式 Detailed ways

参见图1~4,本实用新型由光源部分和包含光电转换电路、运放电路的检测部分构成,光源部分设有脉冲发生电路1与灯驱动电路2,脉冲发生电路的输出端连接到灯驱动电路;检测部分在光电转换电路3设置两组到五组光电二极管及相应初级运放,在光电二极管表面加装通透不同波长光的滤光片,光电转换电路3和运放电路5之间添接陷波电路4;在检测部分后添加数据处理部分,该部分由采样接口电路6、数模转换芯片7、单片机控制系统8顺次连接构成,检测电路中的运放电路输出到采样接口电路。 Referring to Figures 1-4, the present invention is composed of a light source section and detection section includes a photoelectric conversion circuit, the operational amplifier circuit, the output of the light source portion is provided with a pulse generating circuit 2 and the lamp driving circuit, the pulse generating circuit connected to the lamp driving circuit; detecting photoelectric conversion circuit section 3 is provided in two to five set of photodiodes and the corresponding primary operational amplifier, the photodiode surface of the transparent installation of filter different wavelengths of light, the photoelectric conversion circuit 3 and the operational amplifier circuit 5 between spliced ​​notch circuit 4; adding the detection data processing section after section, the portion of the interface by the sampling circuit 6, a digital to analog converter chip 7, 8 are sequentially connected SCM system configuration, the output of the detection circuit operational amplifier circuit to the sampling interface circuit. 检测仪发出的光经人体组织散射/反射后,由两组带滤光片的光电二极管检测相应范围波长内的单色光,接收转化为模拟电信号,在测试仪的模拟电路部分,对模拟信号进行滤波、放大等处理,然后经过模/数转换,在单片机控制下输出贮存结果。 After human tissues light scattered / reflected by monochromatic light with a photodiode detector two respective filter wavelength range emitted by the detector receives the conversion of an analog electrical signal, the analog circuit tester, the analog signal filtering and amplification process, and then through an analog / digital converter, the output of the results of storage under the control of the microcontroller. 显然,根据检测脑组织血、氧含量的单色光波长具体需要,带滤光片的光电二极管可设置两组到五组,相应初级运放、陷波和运放部分也随之设置相应的两组到五组即可。 Obviously, the detection of blood in brain tissue, the specific monochromatic wavelength required oxygen content, the filter may be a photodiode with two sets of five groups to the corresponding primary operational amplifier, op amp, and a notch portion is also provided along with the corresponding two to five groups can be.

为了提供检测仪以可变强度的脉冲光源,光源部分的脉冲发生电路1包括运算放大器U4B、二极管D3、D4和电阻R6、R7、R8、R9、R10以及电容C3,二极管D3、D4和电阻R6并联后和电容C3、电阻R7串联组成积分器反馈到运算放大器U4B的反相端,电阻R8、R9、R10串联组成正反馈;光源部分的灯驱动电路2包括运算放大器U4A和达林顿管Q1、电阻R11、R12、R13、R14、R15、R16、R17、开关S、灯泡G,开关S的两个触点S1、S2分别接电阻R13和电阻R14,电阻R11、R12、R13、R14相互并联后接到运算放大器U4A的正相端,达林顿管Q的发射极上电阻R16、R17相互串联后和灯泡G并联,运算放大器U4A的反相端接在电阻R16、R17之间。 In order to provide the detector pulsed light source of variable intensity, the pulse generating circuit of the light source section 1 comprises an operational amplifier U4B, diodes D3, D4 and resistors R6, R7, R8, R9, R10 and a capacitor C3, diode D3, D4 and resistor R6 and after the parallel capacitor C3, a resistor R7 in series to the integrator feedback inverting terminal of the operational amplifier U4B, resistors R8, R9, R10 in series positive feedback; source lamp driving circuit section 2 comprises an operational amplifier and a Darlington Q1 U4A two contacts S1 resistors R11, R12, R13, R14, R15, R16, R17, switch S, lamp G, switch S, S2 are respectively connected to resistors R13 and resistor R14, resistor R11, R12, R13, R14 connected in parallel after receiving the positive phase of the operational amplifier U4A terminal Q of Darlington emitter electrode resistor R16, the R17 series with each other and parallel lamp G, inverting operational amplifier U4A termination resistors R16, R17 between.

运算放大器U4B组成了多谐振荡器产生方波,D3,D4和R6,C3共同组成积分器把输出电压反馈到反相端。 Composed of the operational amplifier U4B multivibrator generating a square wave, D3, D4 and R6, C3 together constitute the integrator output voltage feedback to the inverting input. D4和D3在导通时的电压基本是恒定的,因此可以在积分电路充放电时起限幅作用,而且还可以作为振荡是否开始的指示。 D3 and D4 turn-on voltage is substantially constant, and therefore can play a role in the limiter circuit integrating charge and discharge, but also as an indication of whether to start the oscillation. R7作为分压电阻保证积分电路的正常运行。 Dividing resistors R7 as to ensure the normal operation of the integrating circuit. R8、R9、R10组成正反馈,使得运算放大器输出能够迅速达到饱和。 R8, R9, R10 composed of positive feedback, so that the output of the operational amplifier quickly reaches saturation. 当积分电容C3上的电压略高于运算放大器正相端的电压时,运算放大器输出迅速跳转到负饱和值,当积分电容C3上的电压略低于运算放大器正相端的电压时,运算放大器输出迅速跳转到正饱和值,如此循环不已,形成一系列方波。 When the voltage across the integrating capacitor C3 is slightly higher than the operational voltage of the positive phase of the amplifier, the operational amplifier output to the negative saturation value jump quickly, when the voltage on the integrating capacitor C3 is slightly lower than the operation voltage of the positive phase of the amplifier, the output of the operational amplifier quickly jump to a positive saturation value, and the cycle, forming a series of square waves. 当调节R10时,正相端的分压随之改变,积分电容上的电压到达正相端电压值的时间也会改变,从而引起输出方波的频率的改变。 When the adjustment R10, the positive-phase terminal partial pressure will change the voltage on the integrating capacitor arrival time of the positive-phase voltage values ​​will change, causing the change in frequency of the square wave output.

运算放大器U4A和达林顿管Q组成恒压源驱动灯泡发光,本实用新型达林顿管Q采用TIP122。 An operational amplifier U4A Darlington driver transistor Q constant voltage source composed of light bulbs, the present invention uses a Darlington transistor Q TIP122. 其工作原理是,从运算放大器U4B输出的方波经过电阻R11,R12,R13,R14的反压作用后加到运算放大器U4A的正相端,根据运算放大器“虚短”的原理,其反相端的电压应与正相端相同,因此可以认为R17上的电压和R11上的电压相等,同时根据“虚断”原理,通过运算放大器的正相端和反相端的电流可以忽略,可以认为流经R16和R17的电流是相等,因此当方波处于高电平时,R16上产生恒定的电压,TIP122的发射极也产生恒定的电压,灯泡G就会在恒压的情况下发光,保持其光强不变。 Its working principle is, square wave output from the operational amplifier U4B via a resistor R11, R12, R13, operational amplifier U4A added after the back pressure acting R14-inverting terminal of the operational amplifier according to the "virtual short" principle, inverts voltage terminal should inverting terminal the same, it is considered that the voltage on the voltage and R11 on the R17 are equal, and in accordance with "virtual break" principle, negligible current operational amplifier inverting terminal and the inverting terminal through can be considered to flow through R16 and R17 are equal currents, so that when the square wave is at a high level, a constant voltage across R16, the emitter TIP122 also generates a constant voltage, the lamp will emit light in the case where G is a constant pressure to keep the light intensity does not change. 当方波处于低电平时,R16上的电压为零,TIP122的发射极的电压也为零,灯泡熄灭。 When the square wave is at a low level, the voltage on R16 to zero, TIP122 emitter voltage is also zero, the lamp goes out. 当开关S切换到不同的档位时,R11上的分压也会不同,使得TIP122的发射极的电压发生改变,从而改变了灯泡G的供电电压,达到改变灯源的发光强度的目的。 When the switch S is switched to a different gear position, the partial pressure of R11 will be different, so that the emitter voltage TIP122 changed, thus changing the supply voltage of the G lamp, the purpose of changing the emission intensity of the light source.

为了有效提取检测用光信号,光电转换电路3中每个光电二极管的相应初级运放是由运算放大器和与光电二极管串联的电阻组成的放大器,各个放大器的反馈电阻之间串联平衡调节电路;陷波电路4采用有源双T网络的后面加运算放大器构成的有源双T带阻滤波器,每组光电二极管的相应初级运放后配两个同样的有源双T带阻滤波器。 In order to effectively extract the light detection signal, the primary operational amplifier 3 corresponding to each photoelectric conversion of the photodiode amplifier circuit is an operational amplifier and a resistor in series with the photodiode composed of a series feedback resistor between each amplifier balance adjustment circuit; trap 4 wave circuit using active double-T bandstop filter network behind the active double T plus operational amplifier, the respective primary transport photodiodes each with the same two active double T bandstop filter after release. 本实用新型中用来探测光信号的器件是光电二极管D1和D2,为了检测单色光,在光电二极管的表面添加了滤光片,分别实现对760nm-850nm范围内的单色光信号的检测。 In the present invention for detecting the optical signal devices are photodiodes D1 and D2, in order to detect monochromatic light, the surface of the photodiode add filters, respectively, to achieve detection of the monochromatic signals within the range of 760nm-850nm . 而光电二极管输出电流小,一般只有数微安。 And the photodiode output current is small, typically only a few microamps. 将接收的光信号变成与之成比例的微弱电流信号后,通过运算放大器和与光电二极管串联的电阻组成的放大器变换成电压信号。 After receiving an optical signal proportional thereto becomes weak current signal, an amplifier and an operational amplifier via a resistor in series with the photodiode into a voltage signal composed. 其基本电路如图3所示。 The basic circuit shown in Figure 3. 光电二极管相当于一个电流源,当它的负载阻抗为零时,输出特性最好。 A photodiode corresponding to a current source, the load impedance when it is zero, the best output characteristic. 而理想的运放正好有“虚短”(即两输入端之间电压差为零)的特性,这正是选用运放来检测光电二极管管电流的原因。 Ideally exactly the op amp "virtual short" (i.e., the voltage difference between the two input terminals is zero) characteristics, which is the reason for the choice of the operational amplifier to detect a tube current of the photodiode. 理想的运放输入端还具有“虚断”(即输入端不取用电流)的特性,光电二极管D1和D2产生的电流流过反馈电阻R1,R2转换为电压,从而实现了光→电流→电压的线性变换。 Ideal operational amplifier having an input terminal further characteristic "virtual OFF" (i.e., no input current access), the photo current generated by the diodes D1 and D2 flowing through the feedback resistors R1, R2 is converted to a voltage, thereby achieving an optical current → → voltage linear transformation. 本实用新型采用TLC277集成放大器做为运放U1A、U1B,TLC277是低噪声的高性能运放,可以很好的实现这种转换。 The present invention uses as a TLC277 operational amplifier integrated amplifier U1A, U1B, TLC277 high-performance low-noise amplifier, such conversion can be well achieved. 电容C1和C2的值很小,能够让信号自由通过,而抑制高频振荡。 Capacitors C1 and C2 is very small, to allow free passage of signals, to suppress high frequency oscillations. R5、R6、R7组成平衡调节电路,可以同时调节两路信号的大小使之平衡。 R5, R6, R7 balancing composition to balance the size of the adjustment circuit, two signals can be adjusted simultaneously. 本实用新型的陷波电路4设计采用有源双T陷波电路,T网络具有选频作用,在低频段由于电容容抗非常大,输入信号通过电阻传输,在高频段电容容抗非常小,输入信号通过电容传输,当信号频率与特征频率wn=1RC]]>相等时,阻抗很大,使传输系数几乎为零,实现陷波作用,但其陷波特性差,且无带负载的能力。 The present invention trap circuit design using active 4 twin-T notch circuits, frequency selective T network action, at low frequencies due to the capacitive reactance is large, the input signal is transmitted through the resistance, capacitance at high frequencies the capacitance is very small, input signal is transmitted through the capacitor, wherein when the signal frequency and the frequency wn = 1RC]]> are equal, a large impedance, so that the transmission coefficient is almost zero, the notch filter effect, but its notch characteristic difference, with a load capacity and no . 为实现一定的陷波特性,在双T网络的后面加运放构成有源双T带阻滤波器,本实用新型配合光电二极管的每组陷波电路都采用两组重复相同的陷波器,由U2A和U2B、U3A和U3B这两组运放分别与双T网络T1、T2、T3、T4构成,对陷波特性进行了改善,提高了电路性能。 In order to achieve a certain notch characteristic, the network behind the double-T plus operational amplifier constituting the active double-T bandstop filter, each trap circuit of the present invention with two photodiodes are used to repeat the same trap by U2A and U2B, U3A and U3B which respectively two double-T op amp network T1, T2, T3, T4 configuration of notch characteristic has been improved, the improved circuit performance. 并且,因为50Hz工频干扰是心电信号的主要干扰源,本实用新型设计陷波电路参数使其专门用于滤掉50Hz工频干扰。 Further, since the 50Hz frequency interference is the major source of interference in the ECG signal, the present invention designed specifically so that the trap circuit parameters for filtering 50Hz frequency interference. 经过陷波电路与运放电路后,两个光电二极管接受的光信号分别转化为了模拟电信号S760和S850。 After the trap circuit with the op amp circuit, two photodiodes receiving the optical signals are converted to analog electric signals S760 and S850.

为了将模拟信号转换为处理结果,数据处理部分的采样接口电路6由8选1的模拟开关U6和运算放大器U7构成的跟随器组成;数据处理部分的单片机系统7采用锁存器U9和编码器U10作为单片机U11和数模转换芯片U8间的控制连接,单片机系统包含内置的显示器、键盘、描迹器、存储器和打印机。 In order to convert the analog signal processing result, sampling interface circuit 6 from the data processing section 8 is selected from the follower analog switch U6 and U7 operational amplifier 1 is constituted with; SCM system using the data processing portion 7 and the encoder latches U9 U10 U11 as a control between the microcontroller and digital to analog chip U8 is connected to the SCM system comprising a built-in monitor, a keyboard, a trace, a memory and printer. 本实用新型电路利用CD4051芯片作为8选1的模拟开关U6,实现对760nm-850nm范围内信号的分时采样。 The present invention circuit uses an analog switch CD4051 chips U6 8-to-1, to achieve time-sampled signal within a range of 760nm-850nm. 由单片机送来的采样控制信号在低电平时CD4051选择X0通道接通,将S760信号送入数模转换芯片U8,高电平时选择X1通道接通,将S850信号送入数模转换芯片U8,以此实现分时采样。 Sampling control signal sent by the microcontroller at a low level X0 CD4051 selected channel is turned on, the signal S760 into the digital-analog converter chip U8, X1 selected channel is turned on when a high level, the signal S850 into the digital-analog converter chip U8, in order to achieve time-sampling. U7组成的跟随器输出电阻很小,减少了后级负载变动对信号的影响。 U7 composition follower output resistance is small, the effect of reducing the load change on the signal level. 单片机U11的数据输入和数模转换芯片U8间的数据输出、锁存器U9的数据输出之间通过总线连接起来,单片机U11与数模转换芯片U8之间设置编码器U14。 A data output between a data input of the microcontroller U11 digital to analog conversion chip U8, U9 between the data output of the latch is connected by a bus, the encoder is provided between the microcontroller U11 and U14 DAC chip U8. 本实用新型采用3/8译码器74LSl38作为U10,A/D转换芯片AD574A作为U8,U10的一个输出Y1连接U8的片选端口CS,片选数模转换芯片U8,从而实现单片机U11控制下的数据转换、数据锁存、数据传递。 The present invention uses the 3/8 decoder 74LSl38 as U10, A / D conversion chip AD574A chip selection port CS U8 is connected as U8, Y1 U10 outputs a chip select digital-analog converter chip U8, U11 control so SCM data conversion, data latch, data transfer. 检测仪内置显示器、键盘、描迹器、存储器和打印机,使用者可以根据需要即时存贮数据或输出数据。 Detector built-in display, a keyboard, a trace, a memory and a printer, the user can immediately store data or output data as needed.

本实用新型的工作原理:将多波长脑组织血、氧检测仪的光源部分置于被测组织上,发出的光经人体组织散射/反射后,由检测仪中的光电检测器件接收,在检测仪的模拟电路部分,对模拟信号进行滤波、放大等处理,然后经过模/数转换,使用单片机控制系统8,将数据进行计算并将其存入存储器,同时将结果送显示屏显示脑血、氧含量变化值和血、氧波形,且在键盘的控制下,进行报告输出,其报告输出由内嵌打印机完成,根据使用需要,可将原始数据存入存储器中,存储的数据使用者可随时调出、输入,可同时送打印机打印结果和血、氧波形。 Working principle of the present invention: The multi-wavelength light source section cerebral blood oxygen detector is placed on the measured tissue, sent, received by the photoelectric detector after the light detection device body tissues scattered / reflected at the detection instrument analog circuit, the analog signal filtering and amplification process, and then through an analog / digital converter, a control system using the microcontroller 8, the data are calculated and stored in the memory while the display shows the results sent cerebral, variation value and blood oxygen content, oxygen waveform, and under the control of the keyboard, report output, the report output is done by the embedded printer, according to the use required, the raw data may be stored in memory, the data stored in the user may at any time recall, input can be simultaneously sent to the printer and print the results of blood, oxygen waveform. 血氧波形也可在描迹器上描绘。 Oxygen may be drawn on the waveform trace device. 在需要计算机处理数据的情况下,可由单片机提供输出接口,输出接口与计算机相连,通过接口将测试仪的测试结果采集到计算机中,通过相应的软件进行分析处理。 In case of need a computer for processing data, an output interface provided by the microcontroller, an output interface connected to the computer, via the interface tester test results will be collected into a computer, analyzed and processed by the appropriate software.

Claims (5)

1.一种多波长近红外脑组织血氧检测仪,由光源部分和包含光电转换电路、运放电路的检测部分构成,其特征在于:1)光源部分设有脉冲发生电路与灯驱动电路,脉冲发生电路的输出端连接到灯驱动电路;2)检测部分包含在光电转换电路设置的两组到五组光电二极管及相应初级运放,在光电二极管表面加装通透不同波长光的滤光片,光电转换电路和运放电路之间添接陷波电路;3)在检测部分后添加数据处理部分,该部分由采样接口电路、数模转换电路、单片机系统顺次连接构成,检测电路中的运放电路输出到采样接口电路。 1. A multi-wavelength near-infrared brain tissue oxygen detector, composed of a light source section and detection section includes a photoelectric conversion circuit, the operational amplifier circuit, comprising: 1) a light source section is provided with the lamp driver circuit pulse generating circuit, the output terminal of the pulse generating circuit connected to the lamp driving circuit; 2) detecting section included in the two to five set of photodiodes and the photoelectric converting circuit is provided corresponding to the primary operational amplifier, the photodiode surface of the transparent installation of different wavelengths of light filter spliced ​​between the sheets, the photoelectric conversion circuit and a trap circuit operational amplifier circuit; 3) adding the detection data processing section in the portion which the interface circuit by the sampling, digital to analog conversion circuit, in turn connected to the microcontroller system configuration, the detection circuit the operational amplifier circuit to the sampling output interface circuit.
2.根据权利要求1所述的多波长近红外脑组织血氧检测仪,其特征在于:光源部分的脉冲发生电路包括运算放人器[U4B]、二极管[D3、D4]和电阻[R6、R7、R8、R9、R10]以及电容[C3],二极管[D3、D4]和电阻[R6]并联后和电容[C3]、电阻[R7]串联组成积分器反馈到运算放大器[U4B]的反相端,电阻[R8、R9、R10]串联组成正反馈;光源部分的灯驱动电路包括运算放大器[U4A]和达林顿管[Q1]、电阻[R11、R12、R13、R14、R15、R16、R17]、开关[S]、灯泡[G],开关[S]的两个触点[S1、S2]分别接电阻[R13]和电阻[R14],电阻[R11、R12、R13、R14]相互并联后接到运算放大器[U4A]的正相端,达林顿管[Q]的发射极上电阻[R16、R17]相互串联后和灯泡[G]并联,运算放大器[U4A]的反相端接在电阻[R16、R17]之间。 2. The multi-wavelength according to a near-infrared detector brain tissue oxygen as claimed in claim, wherein: a pulse light source section generating circuit comprises an operational unit release [U4B], diode [D3, D4] and resistance [R6, R7, R8, R9, R10] and a capacitor [C3], diode [D3, D4] and the resistance [R6] after parallel and a capacitor [C3], resistance [R7] in series integrator feedback to the operational amplifier [U4B] trans phase terminal, a resistor [R8, R9, R10] positive feedback in series; a light source lamp driving circuit portion comprises an operational amplifier [U4A] and Darlington [Ql], resistance [R11, R12, R13, R14, R15, R16 , R17], switch [S], bulb [G], switch [S] of the two contacts [S1, S2] are resistor [R13] and resistance [R14], resistance [R11, R12, R13, R14] after transmitting the operational amplifier connected in parallel to the [U4A] the inverting terminal, Darlington [Q] on the resistance of the electrode [R16, R17] connected in series with each other and inverts the lamp [G] in parallel to the operational amplifier [U4A] of terminating resistor between [R16, R17].
3.根据权利要求1或2所述的多波长近红外脑组织血氧检测仪,其特征在于:光电转换电路中每个光电二极管的相应初级运放是由运算放大器和与光电二极管串联的电阻组成的放大器,各个放大器的反馈电阻之间串联平衡调节电路;陷波电路采用有源双T网络的后面加运算放大器构成的有源双T带阻滤波器,每组光电二机管的相应初级运放后配两个同样的有源双T带阻滤波器。 The multi-wavelength or claim 2 in brain tissue oxygen near infrared detector as claimed in claim, characterized in that: a photoelectric conversion circuit corresponding to each photodiode of the primary operational amplifier is an operational amplifier connected in series with the photodiode and a resistor amplifier, and a feedback resistor connected in series between the balance adjustment of each amplifier circuit; a trap circuit using active double-T bandstop filter network behind the active double T plus operational amplifier, the photodiode each respective primary tube dryer after the operational amplifier with the same two active double-T bandstop filter.
4.根据权利要求1或2所述的多波长近红外脑组织血氧检测仪,其特征在于:数据处理部分的采样接口电路由8选1的模拟开关[U6]和运算放大器[U7]构成的跟随器组成;数据处理部分的单片机系统采用锁存器[U9]和编码器[U10]作为单片机[U11]和数模转换芯片[U8]间的采样控制,单片机系统包含内置的显示器、键盘、描迹器、存储器和打印机。 The multi-wavelength or claim 2 in brain tissue oxygen near infrared detector as claimed in claim, characterized in that: the interface circuit sampling the data processing section 8 is selected by the analog switch 1. [U6] the operational amplifier [U7] configuration follower composition; SCM system using a data processing section latch [U9], and an encoder [U10] as SCM [U11] control digital to analog converter chip sampling, the SCM system [U8] contains between built-in monitor, keyboard , trace, a memory and printer.
5.根据权利要求3所述的多波长近红外脑组织血氧检测仪,其特征在于:数据处理部分的采样接口电路由8选1的模拟开关[U6]和运算放大器[U7]构成的跟随器组成;数据处理部分的单片机系统采用锁存器[U9]和编码器[U10]作为单片机[U11]和数模转换芯片[U8]间的采样控制,单片机系统包含内置的显示器、键盘、描迹器、存储器和打印机。 The multi-wavelength 3 according to the near-infrared detector brain tissue oxygen as claimed in claim, characterized in that: the interface circuit sampling the data processing section 8 is selected by the analog switch 1 of [U6] the operational amplifier [U7] follower configuration composed; SCM system using a data processing section latch [U9], and an encoder [U10] as SCM [U11] control digital to analog converter chip sampling, the SCM system [U8] contains between built-in monitor, keyboard, described tracer, and the printer memory.
CN 200320125532 2003-12-23 2003-12-23 Multiple wave-length near-infrared instrument for testing blood-oxygen content in brain tissue CN2691489Y (en)

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US8805465B2 (en) 2010-11-30 2014-08-12 Covidien Lp Multiple sensor assemblies and cables in a single sensor body
US8818473B2 (en) 2010-11-30 2014-08-26 Covidien Lp Organic light emitting diodes and photodetectors
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US8068891B2 (en) 2006-09-29 2011-11-29 Nellcor Puritan Bennett Llc Symmetric LED array for pulse oximetry
US8175667B2 (en) 2006-09-29 2012-05-08 Nellcor Puritan Bennett Llc Symmetric LED array for pulse oximetry
CN101158676B (en) 2006-12-31 2011-12-14 段建军 Oxygen carrying blood substitutes and a method of evaluating, analyzing method and apparatus of oxygen release function
US8532751B2 (en) 2008-09-30 2013-09-10 Covidien Lp Laser self-mixing sensors for biological sensing
CN101849821A (en) * 2010-06-13 2010-10-06 华中科技大学 Optical fiber near-infrared spectrometer
US8649838B2 (en) 2010-09-22 2014-02-11 Covidien Lp Wavelength switching for pulse oximetry
US8805465B2 (en) 2010-11-30 2014-08-12 Covidien Lp Multiple sensor assemblies and cables in a single sensor body
US8818473B2 (en) 2010-11-30 2014-08-26 Covidien Lp Organic light emitting diodes and photodetectors
CN103424716A (en) * 2012-05-17 2013-12-04 安徽宏实光机电高科有限公司 Lamp tube detection system based on application of color sorter
CN108186028A (en) * 2017-12-28 2018-06-22 中国科学院自动化研究所 Non-contact detection system for cerebral blood oxygen

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