CN223732151U

CN223732151U - Paclitaxel draws enrichment facility

Info

Publication number: CN223732151U
Application number: CN202520121873.1U
Authority: CN
Inventors: 刘建
Original assignee: Hubei Kangshizhen Pharmaceutical Technology Co ltd
Current assignee: Hubei Kangshizhen Pharmaceutical Technology Co ltd
Priority date: 2025-01-20
Filing date: 2025-01-20
Publication date: 2025-12-30
Anticipated expiration: 2035-01-20

Abstract

The utility model relates to the technical field of extraction devices and discloses a paclitaxel extraction and concentration device, which comprises a box body, wherein crushing rollers are rotatably connected to two ends of the top of the inner wall of the box body, first hairbrushes are penetrated and slidably connected to the top of the box body, a filter screen is fixedly connected to the middle of the inner wall of the box body, a first cutting rod penetrates and rotatably connected to the top of the filter screen, a shell is penetrated and rotatably connected to the outer ring of the first cutting rod, a first bevel gear is fixedly connected to the outer ring of the first cutting rod, and second bevel gears are rotatably connected to two sides of the inner wall of the shell. According to the utility model, through the cooperation among the crushing roller, the first hairbrush, the first cutting rod, the second cutting rod, the first bevel gear, the second bevel gear, the third bevel gear, the fourth bevel gear, the first servo motor and the shell, the red bean shirts can be crushed rapidly and effectively through the synergistic effect of the crushing roller and the cutting rod, and the extraction efficiency is improved.

Description

Paclitaxel draws enrichment facility

Technical Field

The utility model relates to the technical field of extraction devices, in particular to a paclitaxel extraction and concentration device.

Background

Paclitaxel (Paclitaxel) is a chemotherapeutic agent extracted from the bark of the pacific yew tree (Taxus brevelfolia) and is widely used for the treatment of a variety of cancers including ovarian cancer, breast cancer and non-small cell lung cancer. It inhibits proliferation of tumor cells by inhibiting cell division, interfering with the normal function of microtubules. Paclitaxel is commonly used in combination with other chemotherapeutic agents to significantly improve patient prognosis and survival. Although its side effects may include alopecia, nausea and immune system suppression, its clinical effects make it one of the important drugs in cancer treatment.

The method for crushing the taxus chinensis by the paclitaxel extraction device is to use a mechanical crusher. First, the collected bark or branches of Taxus chinensis are dried to reduce the moisture. The dried material is then placed in a mechanical crusher for crushing, and common equipment includes blade or hammer crushers to achieve the desired particle size. And finally, collecting crushed taxus fragments, and preparing for subsequent paclitaxel extraction treatment.

Mechanical crushing may cause uneven particle size of crushed aggregates, affect subsequent extraction efficiency, and may not be ideal for certain types of taxus chinensis materials (such as biological samples in a wet state), so that the extraction efficiency is reduced, and efficient crushing of taxus chinensis cannot be performed.

Disclosure of utility model

The utility model aims to provide a paclitaxel extraction and concentration device, which solves the problem that the taxus chinensis cannot be crushed efficiently in the background technology.

In order to achieve the purpose, the paclitaxel extraction and concentration device comprises a box body, wherein two ends of the top of the inner wall of the box body are respectively and rotatably connected with a crushing roller, the top of the box body is respectively and rotatably connected with a first hairbrush, a filter screen is fixedly connected in the middle of the inner wall of the box body, the top of the filter screen is respectively and rotatably connected with a first bevel gear, an outer ring of the first bevel gear is respectively and rotatably connected with a shell, the outer ring of the first bevel gear is fixedly connected with a first bevel gear, two sides of the inner wall of the shell are respectively and rotatably connected with a second bevel gear, the second bevel gears are respectively and rotatably connected with the first bevel gears, one end of each second bevel gear is fixedly connected with a second bevel gear, the bottom of each first bevel gear is fixedly connected with a third bevel gear, the bottom of each first bevel gear is respectively and rotatably connected with a filter screen, one side of the box body is fixedly connected with a first servo motor, the output end of each first servo motor is fixedly connected with a fourth bevel gear, the fourth bevel gear is respectively and rotatably connected with a shell, two sides of each cleaning assembly are respectively, and the two sides of the cleaning assembly are fixedly connected with a cleaning assembly.

Through adopting above-mentioned technical scheme, through the meshing between the bevel gears, the fourth bevel gear drives third bevel gear and produces rotatablely, and third bevel gear drives first cutting rod and produces rotatablely, can make first bevel gear drive the second bevel gear simultaneously and produce rotatablely.

As further description of the technical scheme, the cleaning assembly comprises two second servo motors, wherein the second servo motors are fixedly connected with two ends of one side of the fixed block, the output ends of the second servo motors are fixedly connected with threaded rods, the outer rings of the threaded rods are fixedly connected with sliding plates, the inner walls of the sliding plates are fixedly connected with first springs, and one ends of the first springs are fixedly connected with second hairbrushes.

Through adopting above-mentioned technical scheme, drive the threaded rod through the second servo motor and produce the rotation, make the slide produce the removal.

As further description of the technical scheme, the two sides of the box body penetrate through and are connected with the sealing cover in a sliding manner, one side of the sealing cover is fixedly connected with the rack, and the rear end of the box body is fixedly connected with the fixing frame.

By adopting the technical scheme, the crushed taxus chinensis in the box body can be crushed by opening the sealing cover.

As further description of the technical scheme, one side of the fixing frame is fixedly connected with a third servo motor, and the output end of the third servo motor is fixedly connected with a rotating rod.

By adopting the technical scheme, the third servo motor drives the rotating rod to rotate.

As further description of the technical scheme, the outer rings of the rotating rods are fixedly connected with first gears, and the first gears are in meshed connection with the racks.

By adopting the technical scheme, the rack can be moved by the rotation of the first gear.

As further description of the technical scheme, two ends of the bottom of the inner wall of the box body are rotatably connected with rotating shafts, and the outer ring of each rotating shaft is fixedly connected with a filter plate.

By adopting the technical scheme, the filter plate can filter crushed taxus chinensis.

As further description of the technical scheme, the vibrating motors are fixedly connected to the tops of the two sides of the box body, and damping springs are fixedly connected to the bottoms of the box body.

Through adopting above-mentioned technical scheme, vibrating motor can drive the box and produce the vibration.

As further description of the technical scheme, the top of the sliding plate penetrates through and is connected with the sliding rod in a sliding manner, and the outer ring of the sliding rod is fixedly connected with the box body.

Through adopting above-mentioned technical scheme, the removal of slide can slide in slide bar department to can support the slip of slide.

Compared with the prior art, the utility model has the following beneficial effects:

1. According to the paclitaxel extraction and concentration device provided by the utility model, firstly, through the cooperation among the crushing roller, the first hairbrush, the first cutting rod, the second cutting rod, the first bevel gear, the second bevel gear, the third bevel gear, the fourth bevel gear, the first servo motor and the shell, the red bean shirts can be crushed rapidly and effectively through the synergistic effect of the crushing roller and the cutting rod, the contact surface area in the extraction process is increased, and the extraction efficiency is improved.

2. According to the paclitaxel extraction and concentration device provided by the utility model, through the cooperation among the second servo motor, the threaded rod, the slide plate, the first spring, the second hairbrush, the filter plate, the rotating shaft, the rack, the fixing frame, the third servo motor, the first gear and the rotating rod, the filter plate is automatically cleaned in the discharging process, so that the accumulation of the residues of the taxus chinensis is effectively prevented, the risk of equipment blockage is reduced, and the continuous operation of the equipment is ensured.

Drawings

FIG. 1 is a perspective view of the present utility model;

FIG. 2 is a cross-sectional view of the case of the present utility model;

FIG. 3 is a cross-sectional view of the housing of the present utility model;

FIG. 4 is an exploded view of the spring of the present utility model;

fig. 5 is an exploded view of a first gear according to the present utility model.

Legend description:

1. The device comprises a box body, 2 parts of crushing rollers, 3 parts of first hairbrushes, 4 parts of first cutting rods, 5 parts of second cutting rods, 6 parts of outer shells, 7 parts of filter screens, 8 parts of first bevel gears, 9 parts of second bevel gears, 10 parts of third bevel gears, 11 parts of fourth bevel gears, 12 parts of protective shells, 13 parts of first servo motors, 14 parts of fixed blocks, 15 parts of second servo motors, 16 parts of threaded rods, 17 parts of sliding rods, 18 parts of sliding plates, 19 parts of first springs, 20 parts of second hairbrushes, 21 parts of filter plates, 22 parts of rotating shafts, 23 parts of racks, 24 parts of fixed frames, 25 parts of third servo motors, 26 parts of first gears, 27 parts of rotating shafts, 28 parts of damping springs, 29 parts of vibration motors, 30 parts of sealing covers.

Detailed Description

The technical solutions of the embodiments of the present utility model will be clearly and completely described below with reference to the drawings in the embodiments of the present utility model, and it is apparent that the described embodiments are only some embodiments of the present utility model, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

For a further understanding of the present utility model, reference is made to the following detailed description of the utility model, taken in conjunction with the accompanying drawings.

Referring to fig. 1, the paclitaxel extraction and concentration device of the utility model comprises a box body 1, wherein vibrating motors 29 are fixedly connected to the tops of two sides of the box body 1, the vibrating motors 29 can drive the box body 1 to vibrate, damping springs 28 are fixedly connected to the bottom of the box body 1, the damping springs 28 can buffer the vibration generated by the box body 1, sliding rods 17 are penetrated through and slidingly connected to the tops of sliding plates 18, the sliding plates 18 can slide at the sliding rods 17, and the outer rings of the sliding rods 17 are fixedly connected with the box body 1.

Referring to fig. 2 and 3, both ends of the top of the inner wall of the box body 1 are rotatably connected with a crushing roller 2, an external motor drives the crushing roller 2 to rotate, the top of the box body 1 is penetrated through and slidably connected with a first brush 3, the first brush 3 can wipe the surface of the crushing roller 2, a filter screen 7 is fixedly connected with the middle of the inner wall of the box body 1, the filter screen 7 can filter taxus chinensis, the top of the filter screen 7 is penetrated through and rotatably connected with a first cutting rod 4, the outer rings of the first cutting rod 4 and the second cutting rod 5 are respectively provided with a cutting blade, the outer ring of the first cutting rod 4 is penetrated through and rotatably connected with a shell 6, the shell 6 protects an internal bevel gear, the outer ring of the first cutting rod 4 is fixedly connected with a first bevel gear 8, both sides of the inner wall of the shell 6 are rotatably connected with a second bevel gear 9, and the second bevel gear 9 is connected with the first bevel gear 8 in a meshed manner, the first bevel gear 8 is driven to rotate by the rotation of the first cutting rod 4, one end of the second bevel gear 9 is fixedly connected with the second cutting rod 5, the bottom of the first cutting rod 4 is fixedly connected with the third bevel gear 10, the rotation of the third bevel gear 10 drives the first cutting rod 4 to rotate, the bottom of the first cutting rod 4 penetrates through and is rotationally connected with the protective shell 12, the first servo motor 13 is fixedly connected with the middle of one side of the box body 1, the output end of the first servo motor 13 is fixedly connected with the fourth bevel gear 11, the fourth bevel gear 11 can be driven to rotate by the first servo motor 13, the fourth bevel gear 11 is connected with the third bevel gear 10 in a meshed manner, the two sides of the box body 1 are fixedly connected with the fixed blocks 14, and one side of the fixed blocks 14 is provided with the cleaning assembly.

Referring to fig. 4 and 5, the cleaning assembly comprises two second servo motors 15, the second servo motors 15 are fixedly connected with two ends of one side of the fixed block 14, the fixed block 14 is fixedly connected with the position of the second servo motors 15, the output ends of the second servo motors 15 are fixedly connected with threaded rods 16, the second servo motors 15 drive the threaded rods 16 to rotate, sliding plates 18 are fixedly connected with the outer ring of the threaded rods 16, the sliding plates 18 are made to move through rotation of the threaded rods 16, first springs 19 are fixedly connected with the inner walls of the sliding plates 18, one ends of the first springs 19 are fixedly connected with second hairbrushes 20, the second hairbrushes 20 can be made to cling to filter plates 21 through the first springs 19, two sides of the box 1 are fixedly connected with sealing covers 30 in a penetrating mode, one side of each sealing cover 30 is fixedly connected with racks 23, the movement of each rack 23 drives the sealing covers 30 to move, the rear ends of the box 1 are fixedly connected with fixing frames 24, one side of each fixing frame 24 is fixedly connected with a third servo motor 25, the output ends of each third servo motor 25 are fixedly connected with a rotating rod 27, each rotating rod 27 can be driven to rotate, each rotating rod 27 is fixedly connected with a first gear 26, the inner ring 27 is fixedly connected with the first gear 26, the rotating rod is made to rotate, the first gear 26 is made to rotate, the rotating shafts are made to rotate, and the first gear 26 is meshed with the outer ring 21 is connected with the filter plates 22, and the two ends are fixedly connected with the filter plates 22, and the rotary shafts are meshed with the rotary shafts 22.

The method comprises the working principle that firstly, the Chinese yew is placed at the position of a crushing roller 2 to be crushed, then the surface of the crushing roller 2 can be wiped through a first hairbrush 3, adhesion of the Chinese yew is prevented, then a first servo motor 13 drives a fourth bevel gear 11 to rotate, the third bevel gear 10 drives a first cutting rod 4 to rotate through meshing among bevel gears, the first cutting rod 4 rotates to enable a first bevel gear 8 to rotate, a second bevel gear 9 drives a second cutting rod 5 to rotate, the Chinese yew can be crushed efficiently through cooperation between the first cutting rod 4 and the second cutting rod 5, then the Chinese yew is filtered through a filter screen 7, the crushed Chinese yew falls on a filter plate 21, then a medicament is poured into a box 1, the Chinese yew and the medicament are mixed, the mixed liquid is discharged through a pipeline, after the discharge is completed, the rotation of a rotating shaft 22 drives a rotating rod 27 to rotate, a first gear 26 drives a rack 23 to move, a sealing cover 30 to move, accordingly the Chinese yew 21 can be crushed through cooperation between the first cutting rod 4 and the second cutting rod 5, the Chinese yew can be cleaned through the filter plate 21, and the second hairbrush is discharged through a rotary shaft 16, and the Chinese yew can be discharged through a rotary filter plate 19 in a rotary manner, and the process can be cleaned conveniently.

It is noted that relational terms such as first and second, and the like are used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Although embodiments of the present utility model have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the utility model, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A paclitaxel extraction concentration device comprises a box body (1), and is characterized in that two ends of the top of the inner wall of the box body (1) are rotatably connected with a crushing roller (2), the top of the box body (1) is fixedly connected with a first hairbrush (3) in a penetrating and sliding manner, the middle of the inner wall of the box body (1) is fixedly connected with a filter screen (7), the top of the filter screen (7) is fixedly connected with a first cutting rod (4) in a penetrating and rotating manner, the outer ring of the first cutting rod (4) is fixedly connected with a shell (6) in a penetrating and rotating manner, the outer ring of the first cutting rod (4) is fixedly connected with a first bevel gear (8), two sides of the inner wall of the shell (6) are rotatably connected with a second bevel gear (9) in a meshed manner, one end of the second bevel gear (9) is fixedly connected with a second cutting rod (5), the bottom of the first cutting rod (4) is fixedly connected with a third bevel gear (10), the bottom of the first cutting rod (4) is fixedly connected with a protecting shell (12) in a penetrating and rotating manner, the middle of the box body (1) is fixedly connected with a first bevel gear (13) and the first bevel gear (13) is fixedly connected with a fourth bevel gear (13) in a meshed manner, the cleaning device is characterized in that fixing blocks (14) are fixedly connected to two sides of the box body (1), and cleaning assemblies are arranged on one sides of the fixing blocks (14).

2. The paclitaxel extraction and concentration device according to claim 1, wherein the cleaning assembly comprises two second servo motors (15), the second servo motors (15) are fixedly connected with two ends of one side of the fixed block (14), the output ends of the second servo motors (15) are fixedly connected with threaded rods (16), the outer rings of the threaded rods (16) are fixedly connected with sliding plates (18), the inner walls of the sliding plates (18) are fixedly connected with first springs (19), and one ends of the first springs (19) are fixedly connected with second brushes (20).

3. The paclitaxel extraction and concentration device according to claim 1, wherein the two sides of the box body (1) are penetrated and connected with sealing covers (30) in a sliding manner, one side of each sealing cover (30) is fixedly connected with a rack (23), and the rear end of the box body (1) is fixedly connected with a fixing frame (24).

4. The paclitaxel extraction and concentration device according to claim 3, wherein a third servo motor (25) is fixedly connected to one side of the fixing frame (24), and a rotating rod (27) is fixedly connected to the output end of the third servo motor (25).

5. The paclitaxel extraction and concentration device according to claim 4, wherein the outer rings of the rotating rods (27) are fixedly connected with first gears (26), and the first gears (26) are in meshed connection with the racks (23).

6. The paclitaxel extraction and concentration device according to claim 1, wherein two ends of the bottom of the inner wall of the box body (1) are rotatably connected with rotating shafts (22), and the outer ring of each rotating shaft (22) is fixedly connected with a filter plate (21).

7. The paclitaxel extraction and concentration device according to claim 1, wherein vibration motors (29) are fixedly connected to the tops of two sides of the box body (1), and damping springs (28) are fixedly connected to the bottoms of the box body (1).

8. The paclitaxel extraction and concentration device according to claim 2, wherein the tops of the sliding plates (18) are respectively penetrated through and connected with a sliding rod (17) in a sliding manner, and the outer ring of the sliding rod (17) is fixedly connected with the box body (1).