CN223351904U - Biological cell separation device - Google Patents

Abstract

The utility model discloses a biological cell separation device which comprises a separation placing box, wherein the bottom of the separation placing box is fixedly connected with an equipment box, a motor is fixedly connected inside the equipment box, the top of an output shaft of the motor is fixedly connected with a round end seat, the top of the round end seat is fixedly connected with a round backing plate, the top of the round backing plate is fixedly connected with a round seat, the top of the round seat is provided with a placing mechanism, and the top of the round seat is provided with a lifting mechanism. According to the centrifugal tube clamping device, the round base plate, the round seat, the rectangular rod, the top seat, the placing holes, the silica gel ring and the circular ring are arranged, the placing holes on the top seat are staggered with the placing holes on the round seat, so that a synchronous clamping effect on a plurality of centrifugal tubes is achieved, the centrifugal tubes are prevented from shaking during subsequent separation while the operation is convenient, the rectangular sleeve is sleeved on the rectangular rod to move up and down, and the limiting height of the top seat on the centrifugal tubes is adjusted, so that the gravity center position of the centrifugal tubes is adjusted conveniently.

Description

Biological cell separation device

Technical Field

The utility model relates to the technical field of separation equipment, in particular to a biological cell separation device.

Background

Biological cell separation refers to the process of obtaining cells of interest from tissue after it has been dispersed into a cell suspension. The centrifugal separation of biological cells is a method utilizing centrifugal force, and the centrifugal force is far greater than gravity through high angular velocity generated by equipment such as a centrifugal machine, so that suspended matters in solution are easy to precipitate.

In prior art, separator is when in actual use, needs place the centrifuging tube in proper order on the separation dish in the separator, because the hole of placing that distributes on the separation dish needs to be greater than the diameter of centrifuging tube, leads to unable spacing to the centrifuging tube of different thickness, and when placing the centrifuging tube of different length simultaneously, focus position upwards shifts easily, leads to unstable during centrifugal separation.

Disclosure of utility model

The utility model aims to solve the defects in the prior art and provides a biological cell separation device.

In order to achieve the above purpose, the present utility model adopts the following technical scheme:

The utility model provides a biological cell separator, includes the separation and places the case, the bottom fixedly connected with equipment box of case is placed in the separation, the inside fixedly connected with motor of equipment box, the top fixedly connected with circular end seat of motor output shaft, the top fixedly connected with circular backing plate of circular end seat, the top fixedly connected with circle seat of circular backing plate, the top of circle seat is equipped with placement machine, placement machine includes the rectangle pole, the top of circle seat and the bottom fixed connection of rectangle pole, the outer wall cover of rectangle pole is equipped with the footstock, a plurality of holes of placing have evenly been seted up to the outer wall of footstock and circle seat, the equal fixedly connected with silica gel circle of inner wall of a plurality of holes of placing, the top rotation of circle seat is connected with the ring, can fix the centrifuging tube of thickness different but same batch through setting up placement machine, the top of circle seat is equipped with elevating system.

Preferably, the elevating system includes the rectangle cover, the top of ring and the bottom fixed connection of rectangle cover, the outer wall of rectangle cover is fluted, and the inner wall sliding connection of recess has the disk, the screw hole has all been seted up to the outer wall of rectangle cover and ring, and the equal threaded connection of inner wall of two screw holes has the bolt, one of them the one end of bolt and the outer wall fixed connection of disk, another the one end of bolt extrudees mutually with the top of footstock, through setting up the height of lift adjustment footstock to adjust the focus position of the centrifuging tube that varies.

Preferably, the through hole is set up to the bottom of case is placed in the separation, and the inner wall of through hole rotates with the outer wall of motor output shaft to be connected, drives circular backing plate and a plurality of centrifuging tube through setting up the motor and rotates, forms centrifugal effect.

Preferably, the bottom of circular end seat rotates and inlays has a plurality of balls, and the outer wall of a plurality of balls all contacts with the bottom inner wall of separation placement box, reduces the frictional force between circular end seat and the separation placement box through setting up a plurality of balls.

Preferably, the inner wall of the rectangular sleeve is in sliding connection with the outer wall of the rectangular rod, the outer wall of the wafer is extruded with the outer wall of the rectangular rod, extrusion force between the wafer and the rectangular rod is achieved through rotating the bolts, and the rectangular sleeve can be prevented from moving up and down during centrifugation.

Preferably, the top of the separation placing box is hinged with a box cover, and an electromechanical integrated lock is arranged between the box cover and the separation placing box and adopts the existing lock body and a lock tongue.

Compared with the prior art, the utility model has the advantages that:

According to the scheme, the round base plate, the round seat, the rectangular rod, the top seat, the placing holes, the silica gel ring and the circular ring are arranged, the placing holes in the top seat are staggered with the placing holes in the round seat, so that the clamping effect of a plurality of centrifugal tubes is achieved synchronously, the centrifugal tubes are prevented from shaking during subsequent separation while operation is facilitated, the rectangular rod is sleeved with the rectangular sleeve to move up and down, the limiting height of the centrifugal tubes is adjusted through the top seat, and therefore the gravity center position of the centrifugal tubes is adjusted conveniently.

Drawings

In order to more clearly illustrate the technical solutions of the present utility model, the drawings that are needed in the description of the specific embodiments will be briefly described below, it being obvious that the drawings in the following description are only some examples of the present utility model, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic perspective view of a biological cell separation device according to the present utility model;

FIG. 2 is a schematic cross-sectional view of a biological cell separation device according to the present utility model;

FIG. 3 is an enlarged schematic view of the portion A in FIG. 2 of a biological cell separation device according to the present utility model;

fig. 4 is a schematic partial perspective view of a biological cell separation device according to the present utility model.

The device comprises a box 1, a device box 2, a motor 3, a round end seat 4, a round base 5, a ball, a round base 6, a round pad 7, a round seat 8, a rectangular rod 9, a top seat 10, a placement hole 11, a silica gel ring 12, a circular ring 13, a rectangular sleeve 14, a circular disc 15, a bolt 16 and a box cover.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

The utility model provides a biological cell separator, shown by fig. 1-4, relate to a biological cell separator, including the separation place case 1, the bottom fixedly connected with equipment box 2 of separation place case 1, the inside fixedly connected with motor 3 of equipment box 2, equipment box 2 protects motor 3, the through-hole has been seted up to the bottom of separation place case 1, the inner wall of through-hole is connected with the outer wall rotation of motor 3 output shaft, the top fixedly connected with circular end seat 4 of motor 3 output shaft, motor 3 operation drives circular end seat 4 and rotates.

The bottom of circular end seat 4 rotates and inlays has a plurality of balls 5, and the outer wall of a plurality of balls 5 all contacts with the bottom inner wall of separation placement box 1, and the top fixedly connected with circular backing plate 6 of circular end seat 4, the top fixedly connected with circular backing plate 7 of circular backing plate 6 circular end seat 4 and circular backing plate 6 support circular seat 7.

The top of circle seat 7 is equipped with placement machine and constructs, placement machine constructs including rectangle pole 8, the top of circle seat 7 and the bottom fixed connection of rectangle pole 8, the outer wall cover of rectangle pole 8 is equipped with footstock 9, a plurality of holes 10 of placing have evenly been seted up to the outer wall of footstock 9 and circle seat 7, the equal fixedly connected with silica gel circle 11 of inner wall of a plurality of holes 10 of placing, silica gel circle 11 has the compliance, increase and centrifuge tube between area of contact, play skid-proof ability, the top of circle seat 7 is rotated through current bearing and is connected with ring 12, the outer lane of bearing and the top fixed connection of circle seat 7, the inner circle of bearing and the bottom fixed connection of ring 12, the fixed central point who inlays at footstock 9 of bearing.

The top of circle seat 7 is equipped with elevating system, elevating system includes rectangle cover 13, the inner wall of rectangle cover 13 and the outer wall sliding connection of rectangle pole 8, rectangle cover 13 goes up and down through rectangle pole 8, the outer wall of disk 14 extrudees with the outer wall of rectangle pole 8 mutually, the top of ring 12 and the bottom fixed connection of rectangle cover 13, the recess has been seted up to the outer wall of rectangle cover 13, the inner wall sliding connection of recess has disk 14, the cross-section of recess is circular.

Screw holes are formed in the outer walls of the rectangular sleeve 13 and the circular ring 12, bolts 15 are connected with the inner walls of the two screw holes in a threaded mode, one end of one bolt 15 is fixedly connected with the outer wall of the circular disc 14, one end of the other bolt 15 is extruded with the top of the top seat 9, extrusion force between one end of the bolt 15 and the top seat 9 is large, the top seat 9 is fixed in position through extrusion force and friction force of the bolt 15 during centrifugation, rotation cannot be conducted, the top of the separation placement box 1 is hinged to a box cover 16, and an electromechanical integrated lock is installed between the box cover 16 and the separation placement box 1.

When the centrifugal tube separating and placing box is used, the box cover 16 is opened through the electromechanical integrated lock, the inside of the separating and placing box 1 is exposed, a plurality of centrifugal tubes filled with samples are respectively placed in a plurality of placing holes 10, the bottoms of the centrifugal tubes are in contact with the tops of the round backing plates 6, one of the bolts 15 is rotated to drive the wafer 14 to move outwards, the wafer 14 does not squeeze the outer wall of the rectangular rod 8 any more, the position fixing of the rectangular sleeve 13 is released, the rectangular sleeve 13, the circular ring 12 and the top seat 9 can move up and down through the rectangular rod 8, and the limiting height of the centrifugal tubes is adjusted, so that the gravity center position of the centrifugal tubes can be adjusted conveniently; when spacing a plurality of centrifuging tubes, rotate another bolt 15 and remove the fixed in position to footstock 9, rotate a plurality of holes 10 of placing on the footstock 9 and a plurality of holes 10 of placing on the circular seat 7 and stagger, form the tight effect of pressing from both sides to a plurality of centrifuging tubes, rotate another bolt 15 again, carry out the fixed in position to footstock 9, prevent its rotation, follow-up motor 3 operation drives circular end seat 4 and rotates, forms centrifugal separation effect.

The preferred embodiments of the utility model disclosed above are intended only to assist in the explanation of the utility model. The preferred embodiments are not intended to be exhaustive or to limit the utility model to the precise form disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the utility model and the practical application, to thereby enable others skilled in the art to best understand and utilize the utility model. The utility model is limited only by the claims and the full scope and equivalents thereof.

Claims (6)

1. The utility model provides a biological cell separator, includes that separation places case (1), its characterized in that, the bottom fixedly connected with equipment box (2) of case (1) are placed in the separation, the inside fixedly connected with motor (3) of equipment box (2), the top fixedly connected with circular end seat (4) of motor (3) output shaft, the top fixedly connected with circular backing plate (6) of circular end seat (4), the top fixedly connected with circular seat (7) of circular backing plate (6), the top of circular seat (7) is equipped with placement machine, placement machine includes rectangle pole (8), the top of circular seat (7) and the bottom fixedly connected with of rectangle pole (8), the outer wall cover of rectangle pole (8) is equipped with footstock (9), a plurality of holes (10) have evenly been seted up to the outer wall of footstock (9) and circular seat (7), the inner wall of a plurality of holes (10) are all fixedly connected with silica gel circle (11), the top rotation of circular seat (7) is connected with ring (12), the top of circular seat (7) is equipped with elevating system.

2. The biological cell separation device according to claim 1, wherein the lifting mechanism comprises a rectangular sleeve (13), the top of the circular ring (12) is fixedly connected with the bottom of the rectangular sleeve (13), the outer wall of the rectangular sleeve (13) is provided with a groove, the inner wall of the groove is slidably connected with a circular disc (14), the outer walls of the rectangular sleeve (13) and the circular ring (12) are provided with threaded holes, the inner walls of the two threaded holes are respectively provided with a bolt (15), one end of one bolt (15) is fixedly connected with the outer wall of the circular disc (14), and one end of the other bolt (15) is extruded with the top of the top seat (9).

3. The biological cell separation device according to claim 1, wherein a through hole is formed in the bottom of the separation and placement box (1), and the inner wall of the through hole is rotatably connected with the outer wall of the output shaft of the motor (3).

4. The biological cell separation device according to claim 1, wherein a plurality of balls (5) are rotatably embedded in the bottom of the circular end seat (4), and the outer walls of the balls (5) are contacted with the inner wall of the bottom of the separation placing box (1).

5. A biological cell separation device according to claim 2, wherein the inner wall of the rectangular sleeve (13) is slidingly connected to the outer wall of the rectangular rod (8), and the outer wall of the disc (14) is extruded against the outer wall of the rectangular rod (8).

6. A biological cell separation device according to claim 1, characterized in that the top of the separation housing (1) is hinged with a cover (16), and an electromechanical lock is mounted between the cover (16) and the separation housing (1).