CN222267458U - Peripheral blood mononuclear cell separation device - Google Patents
Peripheral blood mononuclear cell separation device Download PDFInfo
- Publication number
- CN222267458U CN222267458U CN202421031119.0U CN202421031119U CN222267458U CN 222267458 U CN222267458 U CN 222267458U CN 202421031119 U CN202421031119 U CN 202421031119U CN 222267458 U CN222267458 U CN 222267458U
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- China
- Prior art keywords
- fixedly connected
- separation device
- peripheral blood
- blood mononuclear
- mononuclear cell
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Links
- 238000000926 separation method Methods 0.000 title claims abstract description 69
- 210000003819 peripheral blood mononuclear cell Anatomy 0.000 title claims abstract description 41
- 238000007789 sealing Methods 0.000 claims abstract description 21
- 238000013016 damping Methods 0.000 claims description 7
- 238000004140 cleaning Methods 0.000 description 9
- 238000012864 cross contamination Methods 0.000 description 4
- 239000007788 liquid Substances 0.000 description 4
- 210000005259 peripheral blood Anatomy 0.000 description 4
- 239000011886 peripheral blood Substances 0.000 description 4
- 239000003814 drug Substances 0.000 description 3
- 210000005087 mononuclear cell Anatomy 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 230000001680 brushing effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005485 electric heating Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000005201 scrubbing Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
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- Centrifugal Separators (AREA)
Abstract
The utility model discloses a peripheral blood mononuclear cell separation device which comprises an outer cylinder, wherein the inner surface of the outer shell of the separation device is rotationally connected with an outer cylinder, the lower surface of the outer shell of the separation device is fixedly connected with a motor, the output end of the motor is fixedly connected with the lower surface of the outer cylinder, the inner surface of the outer cylinder is movably connected with an inner cylinder, a clamping groove is formed in the outer cylinder, a clamping block is fixedly connected with the outer surface of the inner cylinder, the clamping groove is in clearance fit with the clamping block, the upper surface of the inner cylinder is movably connected with a cover plate, the upper surface of the outer shell of the separation device is rotationally connected with a sealing cover, the upper surface of the sealing cover is fixedly connected with a hydraulic cylinder, the output end of the hydraulic cylinder is fixedly connected with a telescopic rod, the other end of the telescopic rod is fixedly connected with a connecting rod, the side surface of the connecting rod is fixedly connected with bristles, and the side surfaces of the bristles are movably connected with the inner surface of the inner cylinder.
Description
Technical Field
The utility model relates to the technical field of separation devices, in particular to a peripheral blood mononuclear cell separation device.
Background
The existing peripheral blood mononuclear cell separation device is characterized in that after a peripheral blood sample is placed in the separation device, the peripheral blood mononuclear cell is extracted through a filter screen or a centrifugal cylinder, but when the peripheral blood mononuclear cell separation device is used, the peripheral blood mononuclear cell separation device does not have the structure for automatically cleaning the interior of a machine, manual cleaning needs to be repeatedly operated for a plurality of times to ensure sanitation of the interior of the machine, so that time and energy are consumed, for example, chinese patent discloses a peripheral blood mononuclear cell rapid separation device, the application number of the peripheral blood mononuclear cell rapid separation device is 201922205534.9, the liquid medicine can directly enter the interior of the machine through a liquid medicine box and a liquid outlet pipe, the peripheral blood mononuclear cell solution and the liquid medicine can be fully mixed through a stirring blade on the surface of a rotating column, the peripheral blood mononuclear cell solution can be fully separated through a first filter screen and a second filter screen, the interior of the machine can be fully heated through an electric heating network and a heat conducting plate, the separation effect is better, and when the peripheral blood mononuclear cell separation device is used, the internal structure of the peripheral blood mononuclear cell separation device is complex, the peripheral blood mononuclear cell separation device does not have the function of automatically cleaning, and the manual cleaning needs to be repeatedly operated for a plurality of times to ensure sanitation of the interior of the machine, and the time and energy is too much consumed.
Disclosure of utility model
The utility model aims to at least solve one of the technical problems in the prior art, and provides a peripheral blood mononuclear cell separation device, wherein a connecting rod and bristles are driven by a telescopic rod to descend into an inner cylinder through a telescopic rod, the inner cylinder is driven by an outer cylinder to rotate through a motor, so that the bristles can automatically brush the inner surface of the inner cylinder, the workload of operators can be reduced, manual cleaning and maintenance devices are not needed, time and manpower resources are saved, cross contamination is avoided, automatic cleaning can ensure the cleaning of the inner part of the device, and cross contamination among different samples is avoided.
The utility model also provides the peripheral blood mononuclear cell separation device, which comprises a separation device shell, wherein the inner surface of the separation device shell is rotationally connected with an outer cylinder, the lower surface of the separation device shell is fixedly connected with a motor, the output end of the motor is fixedly connected with the lower surface of the outer cylinder, the inner surface of the outer cylinder is movably connected with an inner cylinder, a clamping groove is formed in the outer cylinder, a clamping block is fixedly connected with the outer surface of the inner cylinder, the clamping groove is in clearance fit with the clamping block, the upper surface of the inner cylinder is movably connected with a cover plate, the upper surface of the separation device shell is rotationally connected with a sealing cover, the upper surface of the sealing cover is fixedly connected with a hydraulic cylinder, the output end of the hydraulic cylinder is fixedly connected with a telescopic rod, the other end of the telescopic rod is fixedly connected with a connecting rod, the side surface of the connecting rod is fixedly connected with bristles, the side surface of the bristles is movably connected with the inner surface of the inner cylinder, and the working burden of an operator can be reduced by automatically brushing the inner surface of the inner cylinder through the components.
According to the peripheral blood mononuclear cell separation device disclosed by the utility model, the handle is fixedly connected to the upper surface of the sealing cover, the anti-skid sleeve is fixedly connected to the outer surface of the handle, and the sealing cover is convenient to use through the components.
According to the peripheral blood mononuclear cell separation device disclosed by the utility model, the sealing gasket is fixedly connected to the lower surface of the sealing cover, the side surface of the sealing gasket is movably connected with the inner surface of the separation device shell, and the sealing performance of the sealing cover is conveniently increased through the components.
According to the peripheral blood mononuclear cell separation device disclosed by the utility model, the lifting handle is fixedly connected to the side surface of the shell of the separation device, and the equipment is convenient to move by the components.
According to the peripheral blood mononuclear cell separation device disclosed by the utility model, the lower surface of the shell of the separation device is fixedly connected with the base, and through the components, the bearing equipment is convenient.
According to the peripheral blood mononuclear cell separation device disclosed by the utility model, the lower surface of the base is fixedly connected with the supporting legs, the lower surface of each supporting leg is fixedly connected with the anti-skid pad, and the equipment is conveniently lifted through the components.
According to the peripheral blood mononuclear cell separation device disclosed by the utility model, the heat conducting plate is fixedly connected to the inner surface of the separation device shell, the heater is fixedly connected to the lower surface of the separation device shell, and the output end of the heater is fixedly connected to the side surface of the heat conducting plate.
According to the peripheral blood mononuclear cell separation device disclosed by the utility model, the damping pad is fixedly connected to the side surface of the cover plate, the outer surface of the damping pad is movably connected with the inner surface of the inner cylinder, and the cover plate is convenient to install more tightly and is not easy to fall off through the components.
Advantageous effects
1. Compared with the prior art, this peripheral blood mononuclear cell separator, it drops to the inside of inner tube to bring connecting rod and brush hair through the telescopic link, drive the urceolus through the motor and make the inner tube rotate, make the brush hair can scrub the internal surface of inner tube automatically, can reduce operating personnel's work burden, no longer need manual washing and maintenance device, save time and manpower resources, and avoid cross contamination, self-cleaning can ensure the inside cleanness of device, avoid cross contamination between the different samples, this is very important to the laboratory that needs to handle a plurality of samples, can guarantee separation result's accuracy and reliability.
2. Compared with the prior art, the peripheral blood mononuclear cell separation device has the advantages that the peripheral blood sample is added into the inner cylinder, the inner cylinder is driven to rotate through the motor driving outer cylinder to generate centrifugal force, mononuclear cell separation is carried out, quick and efficient extraction can be carried out, the process of extracting the peripheral blood mononuclear cells through the centrifugal force is relatively quick and efficient, the separation of cells can be completed in a short time, the experimental efficiency is improved, and when the peripheral blood mononuclear cells are extracted through the centrifugal force, chemical reagents or enzyme treatment can be avoided, so that the integrity and the bioactivity of the cells can be better maintained.
Drawings
The utility model is further described below with reference to the drawings and examples;
FIG. 1 is a front view showing a constitution of a peripheral blood mononuclear cell separation device according to the present utility model;
FIG. 2 is a cross-sectional view showing a constitution of a peripheral blood mononuclear cell separation device according to the present utility model;
FIG. 3 is a rear view of the peripheral blood mononuclear cell separation device according to the present utility model;
FIG. 4 is a left-view block diagram of the peripheral blood mononuclear cell separation device according to the present utility model.
Legend description:
1. Sealing cover, 2, handle, 3, anti-skid cover, 4, separating device shell, 5, supporting leg, 6, anti-skid pad, 7, hydraulic cylinder, 8, handle, 9, base, 10, telescopic rod, 11, clamping block, 12, clamping groove, 13, cover plate, 14, inner cylinder, 15, outer cylinder, 16, motor, 17, sealing pad, 18, connecting rod, 19, brush hair, 20, damping pad, 21, heat conducting plate, 22 and heater.
Detailed Description
Reference will now be made in detail to the present embodiments of the present utility model, examples of which are illustrated in the accompanying drawings, wherein the accompanying drawings are used to supplement the description of the written description so that one can intuitively and intuitively understand each technical feature and overall technical scheme of the present utility model, but not to limit the scope of the present utility model.
Referring to fig. 1-4, the peripheral blood mononuclear cell separation device comprises a separation device shell 4, a lifting handle 8 is fixedly connected to the side surface of the separation device shell 4 and used for moving equipment by a user, a base 9 is fixedly connected to the lower surface of the separation device shell 4 and used for bearing equipment, a supporting leg 5 is fixedly connected to the lower surface of the base 9, an anti-slip pad 6 is fixedly connected to the lower surface of the supporting leg 5 and used for lifting equipment, a heat conducting plate 21 is fixedly connected to the inner surface of the separation device shell 4 and used for conveniently using, a heater 22 is fixedly connected to the lower surface of the separation device shell 4, the output end of the heater 22 is fixedly connected to the side surface of the heat conducting plate 21 and used for keeping the inside of the equipment constant temperature, an outer cylinder 15 is rotatably connected to the inner surface of the separation device shell 4 and used for driving the inner cylinder to rotate, a motor 16 is fixedly connected to the lower surface of the separation device shell 4, the output end of the motor 16 is fixedly connected to the lower surface of the outer cylinder 15, the inner cylinder 14 is movably connected to the inner cylinder 15 and used for separating mononuclear cells inside.
The outer cylinder 15 is provided with the draw-in groove 12, the surface fixedly connected with fixture block 11 of inner tube 14, draw-in groove 12 and fixture block 11 clearance fit make the urceolus can drive interior movable movement, the upper surface swing joint of inner tube 14 has apron 13 for prevent when rotating, periphery blood sample spill, the side surface fixedly connected with damping pad 20 of apron 13, the surface swing joint of damping pad 20 and the internal surface of inner tube 14 is used for increasing the joint strength of apron, the upper surface rotation of separator shell 4 is connected with sealed lid 1, be used for sealing device, the upper surface fixedly connected with handle 2 of sealed lid 1, the surface fixedly connected with anti-skidding cover 3 of handle 2, be used for the user to use sealed lid.
The lower surface fixedly connected with sealed pad 17 of sealed lid 1, the side surface swing joint of sealed pad 17 and the internal surface swing joint of separator shell 4 for increase sealed tightness of sealed lid, the upper surface fixedly connected with pneumatic cylinder 7 of sealed lid 1, the output fixedly connected with telescopic link 10 of pneumatic cylinder 7 is used for driving the connecting rod and goes up and down, makes the brush hair can scrub the inner tube, the other end fixedly connected with connecting rod 18 of telescopic link 10, the side surface fixedly connected with brush hair 19 of connecting rod 18 is used for scrubbing the inner tube, the side surface swing joint of brush hair 19 and the internal surface of inner tube 14.
The operating principle is that when in use, the separating device shell 4 is opened through the handle 2, the inner cylinder 14 is taken out, the cover plate 13 is opened, the peripheral blood sample is added into the inner cylinder 14, the cover plate 13 is covered back again, the inner cylinder 14 is put back into the outer cylinder 15, the clamping block 11 is inserted into the clamping groove 12, the smooth driving of the clamping block by the outer cylinder 15 is ensured, after the clamping block is placed, the sealing cover 1 is covered back again, the motor 16 is opened, the outer cylinder 15 and the inner cylinder 14 are driven to rotate, the centrifugal force is generated inside the clamping block, the mononuclear cells in the peripheral blood sample are separated, after the cleaning solution is added into the inner cylinder 14, the connecting rod 18 is lowered through the telescopic rod 10, the outer cylinder 15 and the inner cylinder 14 are driven to rotate through the motor 16, and the brush hair 19 brushes the inside.
The embodiments of the present utility model have been described in detail with reference to the accompanying drawings, but the present utility model is not limited to the above embodiments, and various changes can be made within the knowledge of one of ordinary skill in the art without departing from the spirit of the present utility model.
Claims (8)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202421031119.0U CN222267458U (en) | 2024-05-13 | 2024-05-13 | Peripheral blood mononuclear cell separation device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202421031119.0U CN222267458U (en) | 2024-05-13 | 2024-05-13 | Peripheral blood mononuclear cell separation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN222267458U true CN222267458U (en) | 2024-12-31 |
Family
ID=93954033
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202421031119.0U Active CN222267458U (en) | 2024-05-13 | 2024-05-13 | Peripheral blood mononuclear cell separation device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN222267458U (en) |
-
2024
- 2024-05-13 CN CN202421031119.0U patent/CN222267458U/en active Active
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