CN222034698U - MRNA continuous production reaction vessel with self-cleaning function - Google Patents
MRNA continuous production reaction vessel with self-cleaning function Download PDFInfo
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- CN222034698U CN222034698U CN202420662685.5U CN202420662685U CN222034698U CN 222034698 U CN222034698 U CN 222034698U CN 202420662685 U CN202420662685 U CN 202420662685U CN 222034698 U CN222034698 U CN 222034698U
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- fixedly connected
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- 238000004140 cleaning Methods 0.000 title claims abstract description 33
- 238000006243 chemical reaction Methods 0.000 title claims abstract description 24
- 108020004999 messenger RNA Proteins 0.000 title claims abstract description 23
- 238000010924 continuous production Methods 0.000 title claims abstract description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 54
- 238000007789 sealing Methods 0.000 claims abstract description 42
- 238000003756 stirring Methods 0.000 claims abstract description 32
- 238000009434 installation Methods 0.000 claims abstract description 12
- 238000007599 discharging Methods 0.000 claims description 32
- 239000000463 material Substances 0.000 claims description 17
- 238000011049 filling Methods 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 11
- 238000002347 injection Methods 0.000 abstract description 4
- 239000007924 injection Substances 0.000 abstract description 4
- 238000005507 spraying Methods 0.000 abstract description 3
- 238000005406 washing Methods 0.000 abstract description 3
- 238000005516 engineering process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 description 15
- 239000007788 liquid Substances 0.000 description 11
- 239000012535 impurity Substances 0.000 description 8
- 238000012864 cross contamination Methods 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 4
- 239000007921 spray Substances 0.000 description 4
- 238000011010 flushing procedure Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 230000002068 genetic effect Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 210000000805 cytoplasm Anatomy 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 210000003705 ribosome Anatomy 0.000 description 1
- 229920002477 rna polymer Polymers 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/141—Feedstock
Landscapes
- Accessories For Mixers (AREA)
Abstract
本实用新型涉及清洁技术领域，公开了具有自清洁功能的mRNA连续生产反应容器，包括第一密封盖，所述第一密封盖的上表面固定连接有水盒，所述水盒的上表面固定连接有电机，所述高压水管的外壁固定连接有高压喷口，所述第一密封盖的内部开设有安装限位槽，所述第一密封盖的下表面滑动连接有釜体，所述釜体的外壁滑动连接在安装限位槽的内壁，所述第一密封盖的内壁设置有投料组件。本实用新型中，通过注水口向水盒的内部注入水，再通过高压水管外安装的多个角度的高压喷口对釜体的内壁进行高压冲洗，在冲洗时通过电机带动搅拌杆旋转，可以起到对搅拌叶进行清洗的效果，且高压喷口的喷洒角度广阔，使用简单快速，可以减少清洗所需的时间。
The utility model relates to the field of cleaning technology, and discloses an mRNA continuous production reaction container with a self-cleaning function, including a first sealing cover, the upper surface of the first sealing cover is fixedly connected to a water box, the upper surface of the water box is fixedly connected to a motor, the outer wall of the high-pressure water pipe is fixedly connected to a high-pressure nozzle, the interior of the first sealing cover is provided with an installation limit groove, the lower surface of the first sealing cover is slidably connected to a kettle body, the outer wall of the kettle body is slidably connected to the inner wall of the installation limit groove, and the inner wall of the first sealing cover is provided with a feeding assembly. In the utility model, water is injected into the interior of the water box through the water injection port, and then the inner wall of the kettle body is high-pressure washed by high-pressure nozzles at multiple angles installed outside the high-pressure water pipe. During washing, the stirring rod is driven to rotate by the motor, which can play the effect of cleaning the stirring blades, and the high-pressure nozzle has a wide spraying angle, is simple and fast to use, and can reduce the time required for cleaning.
Description
Technical Field
The utility model relates to the technical field of cleaning, in particular to a reaction vessel for continuous production of mRNA with a self-cleaning function.
Background
MRNA, which is collectively referred to as "messenger RNA" (MESSENGER RNA), is a ribonucleic acid that functions in a cell to translate genetic information in DNA into protein. In organisms, DNA stores genetic information, while mRNA transmits this information to ribosomes in the cytoplasm, directing the synthesis of the protein, the self-cleaning function ensures efficient removal of residual material between different batches of reactions or between different production cycles, avoiding the risk of cross-contamination, various byproducts or impurities may be produced during the reaction process, which accumulation may affect the purity and purity of the mRNA, and the self-cleaning function can remove these impurities in time, ensuring high purity of the final product.
But most reation kettle is clean the process complicacy when cleaning, and needs to throw into the manual work more, can influence production efficiency, and in addition partly because the clean angle is not enough leads to unable better clean inside remaining impurity, can appear throwing into the raw materials and lead to cross contamination's problem next time.
Disclosure of utility model
In order to make up for the defects, the utility model provides a reaction vessel for continuous production of mRNA with a self-cleaning function, which aims to improve the problems that the cleaning process is complex, more labor is needed to be input, the production efficiency is affected, and the residual impurities in the reaction vessel cannot be cleaned well due to insufficient cleaning angles, so that cross contamination is caused by the next input of raw materials.
In order to achieve the above purpose, the present utility model provides the following technical solutions:
mRNA continuous production reaction vessel with self-cleaning function, including first sealed lid, the last fixed surface of first sealed lid is connected with the water box, the last fixed surface of water box is connected with the motor, the output fixedly connected with puddler of motor, the water filling port has been seted up to the inner wall of water box, the outer wall rotation of puddler is connected at the inner wall of first sealed lid, the outer wall of puddler is provided with the stirring leaf, the inner wall fixedly connected with high-pressure water pipe of water box, the outer wall fixedly connected with high-pressure spout of high-pressure water pipe, the installation spacing groove has been seted up to the inside of first sealed lid, the lower surface sliding connection of first sealed lid has the cauldron body, the outer wall sliding connection of the cauldron body is at the inner wall of installation spacing groove, the inner wall of first sealed lid is provided with the material subassembly of throwing.
Preferably, the feeding assembly comprises a feeding hole, the outer wall of the feeding hole is fixedly connected with the inner wall of the first sealing cover, the upper surface of the feeding hole is slidably connected with a second sealing cover, the inner wall of the second sealing cover is fixedly connected with a sealing plug, the inside of the second sealing cover is provided with a first sealing groove, the outer wall of the feeding hole is slidably connected with the inner wall of the first sealing groove, and the outer wall of the sealing plug is slidably connected with the inner wall of the feeding hole.
Preferably, the outer wall of the kettle body is fixedly connected with a supporting plate, and the lower surface of the supporting plate is fixedly connected with a supporting leg.
Preferably, the lower surface of the kettle body is fixedly connected with a blanking pipe, and the inner wall of the blanking pipe is fixedly connected with a first discharging pipe.
Preferably, the inner wall of the blanking pipe is fixedly connected with a second discharging pipe, and valves are arranged on the outer walls of the blanking pipe and the first discharging pipe.
Preferably, the outer wall of the second material discharging pipe is fixedly connected with a switching valve, the outer wall of the first material discharging pipe is fixedly connected with the inner wall of the switching valve, and the inner wall of the switching valve is slidably connected with a first piston plate.
Preferably, the outer wall of the first piston plate is fixedly connected with a connecting rod, and one end of the connecting rod is fixedly connected with a second piston plate.
Preferably, the outer wall of the second piston plate is slidably connected to the inner wall of the switching valve, and the inner wall of the switching valve is fixedly connected with a discharge port.
The utility model has the following beneficial effects:
1. according to the utility model, water is injected into the water box through the water injection port, and then the inner wall of the kettle body is subjected to high-pressure flushing through the high-pressure nozzles with multiple angles arranged outside the high-pressure water pipe, and the stirring rod is driven to rotate through the motor during flushing, so that the stirring blade can be cleaned, the spraying angle of the high-pressure nozzles is wide, the use is simple and quick, and the time required for cleaning can be reduced.
2. According to the utility model, the stirring rod and the stirring blade are driven by the motor to rotate, so that the effect of mixing reaction can be achieved in the using process, and the stirring rod and the stirring blade can better clean the residual materials in the kettle body when water is stored in the kettle body during cleaning.
3. In the utility model, the cleaned liquid can be discharged outwards through the second discharging pipe and the first discharging pipe, or the produced product can be discharged outwards, the second discharging pipe and the first discharging pipe can be subjected to a stop valve through the valve, and the liquid entering the switching valve through the second discharging pipe during discharging pushes the second piston plate and the connecting rod to move to the other side, so that the liquid can be discharged outwards through the discharging port, and the cross contamination is prevented during discharging and using.
Drawings
FIG. 1 is a perspective view of a reaction vessel for continuous production of mRNA having a self-cleaning function according to the present utility model;
FIG. 2 is a schematic diagram of a stirring rod of a reaction vessel for continuous production of mRNA with a self-cleaning function;
FIG. 3 is a schematic diagram of a switching valve of a reaction vessel for continuous production of mRNA with self-cleaning function according to the present utility model.
Legend description:
1. A first sealing cover; 2. a water box; 3. a motor; 4. a water filling port; 5. a stirring rod; 6. stirring the leaves; 7. a high pressure water pipe; 8. a high pressure nozzle; 9. a feed inlet; 10. a second sealing cover; 11. a first seal groove; 12. a sealing plug; 13. installing a limit groove; 14. a kettle body; 15. a support plate; 16. a support leg; 17. discharging pipes; 18. a first discharge pipe; 19. a second discharge pipe; 20. a valve; 21. a switching valve; 22. a first piston plate; 23. a connecting rod; 24. a second piston plate; 25. and a discharge port.
Detailed Description
The following description of the embodiments of the present utility model will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the utility model. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.
Referring to fig. 1-2, one embodiment provided by the present utility model is: the mRNA continuous production reaction container with the self-cleaning function comprises a first sealing cover 1, wherein a water box 2 is fixedly connected to the upper surface of the first sealing cover 1, a motor 3 is fixedly connected to the upper surface of the water box 2, a stirring rod 5 is fixedly connected to the output end of the motor 3, a water filling port 4 is formed in the inner wall of the water box 2, the outer wall of the stirring rod 5 is rotationally connected to the inner wall of the first sealing cover 1, stirring blades 6 are arranged on the outer wall of the stirring rod 5, a high-pressure water pipe 7 is fixedly connected to the inner wall of the water box 2, a high-pressure nozzle 8 is fixedly connected to the outer wall of the high-pressure water pipe 7, an installation limiting groove 13 is formed in the inner part of the first sealing cover 1, a kettle body 14 is slidingly connected to the lower surface of the first sealing cover 1, the outer wall of the kettle body 14 is slidingly connected to the inner wall of the installation limiting groove 13, and a feeding component is arranged on the inner wall of the first sealing cover 1; the feeding assembly comprises a feeding hole 9, the outer wall of the feeding hole 9 is fixedly connected to the inner wall of the first sealing cover 1, the upper surface of the feeding hole 9 is slidably connected with a second sealing cover 10, the inner wall of the second sealing cover 10 is fixedly connected with a sealing plug 12, a first sealing groove 11 is formed in the second sealing cover 10, the outer wall of the feeding hole 9 is slidably connected to the inner wall of the first sealing groove 11, and the outer wall of the sealing plug 12 is slidably connected to the inner wall of the feeding hole 9;
Specifically, through the inside water injection of water filling port 4 to water box 2, outwards blowout through high-pressure water pipe 7 and high-pressure spout 8, the high-pressure spout 8 of installation on the high-pressure water pipe 7 is a plurality of, and do not have the interference with high-pressure water pipe 7 when puddler 5 drives puddler 6 and rotates, drive puddler 5 and puddler 6 through motor 3, cooperation high-pressure spout 8 spun clear water, can be better clean the inside impurity of the cauldron body 14, seal the cauldron body 14 through installation spacing groove 13 and first seal groove 11, cover at the surface and the inner wall of feed inlet 9 through second sealed lid 10 and sealing plug 12, can seal the cauldron body 14 after the feeding, clean simple structure in the in-process that uses can be quick use when needs, clean the inside of the cauldron body 14.
Referring to fig. 1-3, a supporting plate 15 is fixedly connected to the outer wall of the kettle body 14, and a supporting leg 16 is fixedly connected to the lower surface of the supporting plate 15; the lower surface of the kettle body 14 is fixedly connected with a blanking pipe 17, and the inner wall of the blanking pipe 17 is fixedly connected with a first discharging pipe 18; the inner wall of the blanking pipe 17 is fixedly connected with a second discharging pipe 19, and valves 20 are arranged on the outer walls of the blanking pipe 17 and the first discharging pipe 18;
specifically, the liquid after cleaning or reaction can flow into the discharging pipe 17 and flow out to one side by opening the valve 20 on any side of the first discharging pipe 18 or the second discharging pipe 19, and the liquid can flow out separately in the using process, so that the effect of cross contamination caused by impurities remained in the pipeline and caused by the next production can be prevented.
Referring to fig. 3, a switching valve 21 is fixedly connected to the outer wall of the second discharge pipe 19, the outer wall of the first discharge pipe 18 is fixedly connected to the inner wall of the switching valve 21, and a first piston plate 22 is slidably connected to the inner wall of the switching valve 21; the outer wall of the first piston plate 22 is fixedly connected with a connecting rod 23, and one end of the connecting rod 23 is fixedly connected with a second piston plate 24; the outer wall of the second piston plate 24 is slidably connected to the inner wall of the switching valve 21, and the inner wall of the switching valve 21 is fixedly connected with a discharge port 25;
Specifically, the liquid enters the switching valve 21 through the second discharging pipe 19 or the first discharging pipe 18, and at this time, the discharged liquid drives the connecting rod 23 to move to the other side by pushing the second piston plate 24 or the first piston plate 22, so that the effect of cross contamination of the pipeline during discharging or cleaning can be prevented, and the effect of protecting materials and preventing waste of materials can be better.
Working principle: when the device is needed to be used, water is injected into the water box 2 through the water injection port 4, the high-pressure water pipe 7 and the high-pressure spray nozzles 8 are sprayed outwards, the high-pressure spray nozzles 8 arranged on the high-pressure water pipe 7 are multiple in the using process, the stirring rod 5 is used for driving the stirring blade 6 to rotate, the stirring rod 5 and the stirring blade 6 are driven to rotate through the motor 3 in the using process, the clean water sprayed by the high-pressure spray nozzles 8 is matched, impurities in the kettle body 14 can be better cleaned, the kettle body 14 is arranged through the installation limiting groove 13 and the first sealing groove 11 in the using process, the high-pressure water pipe 7 and the high-pressure spray nozzles 8 can better clean the impurities in the kettle body 14 in the cleaning process through the limiting of the installation limiting groove 13, the stirring blade 6 can be better rotated and mixed in the kettle body 14 in the process of starting the motor 3, the stirring blade is covered on the surface and the inner wall of the feed inlet 9 through the second sealing cover 10 and the sealing plug 12 in the process of using, the kettle body 14 can be sealed after feeding, the cleaning structure is simple in the process of using, the stirring blade can be quickly used when the stirring blade is needed to be used, the inside of the kettle body 14 can be cleaned, the produced liquid or the cleaned liquid can flow into the inside of the discharging pipe 17 below the kettle body 14 in the process of using, at the moment, the valve 20 on any side of the second discharging pipe 19 or the first discharging pipe 18 is opened to discharge water, the discharged liquid can enter the inside of the switching valve 21 through the second discharging pipe 19 or the first discharging pipe 18, at the moment, the discharged liquid can drive the connecting rod 23 to move to the other side by pushing the second piston plate 24 or the first piston plate 22, the device can prevent the effect of pipeline cross contamination when unloading or clean in the use, the effect of protection material that can be better prevents the material extravagant, the in-process of using the device has not only reached the high-pressure spout 8 through the outer multiple angle of installing of high-pressure water pipe 7 and has carried out high pressure flushing to the inner wall of cauldron body 14, it is rotatory to drive puddler 5 through motor 3 when washing, can play abluent effect to stirring leaf 6, and the spraying angle of high-pressure spout 8 is wide, use simply fast, can reduce the required time of washing, still have and drive puddler 5 and stirring leaf 6 rotatory through motor 3, can carry out the effect of compounding reaction in the in-process of using, and when water is stored in the inside of cauldron body 14 when wasing, play puddler 5 and stirring leaf 6 can be better carry out clean effect to the residual material in the cauldron body 14 still reached through valve 20 can carry out the stop valve to second material pipe 19 and first material pipe 18, and the discharge pipe is through second material pipe 21 and switching valve 24 and the effect that the other side can be moved to the discharge through the second material pipe 21 when discharging, the drain plate 23 at this moment and the other side can prevent pollution to the discharge port when using 25.
Finally, it should be noted that: the foregoing description is only illustrative of the preferred embodiments of the present utility model, and although the present utility model has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described, or equivalents may be substituted for elements thereof, and any modifications, equivalents, improvements or changes may be made without departing from the spirit and principles of the present utility model.
Claims (8)
1. MRNA continuous production reaction vessel with self-cleaning function, including first sealed lid (1), its characterized in that: the utility model discloses a high-pressure water tank, including sealed lid, stirring rod (1) and stirring rod (1), upper surface fixedly connected with water box (2) of first sealed lid (1), upper surface fixedly connected with motor (3) of water box (2), water filling port (4) have been seted up to the inner wall of water box (2), the outer wall of stirring rod (5) rotates the inner wall of connection at first sealed lid (1), the outer wall of stirring rod (5) is provided with stirring leaf (6), the inner wall fixedly connected with high-pressure water pipe (7) of water box (2), the outer wall fixedly connected with high-pressure spout (8) of high-pressure water pipe (7), installation spacing groove (13) have been seted up to the inside of first sealed lid (1), the lower surface sliding connection of first sealed lid (14) is at the inner wall of installation spacing groove (13), the inner wall of first sealed lid (1) is provided with the material throwing the subassembly.
2. The continuous production reaction vessel for mRNA having a self-cleaning function according to claim 1, wherein: the feeding assembly comprises a feeding hole (9), the outer wall of the feeding hole (9) is fixedly connected with the inner wall of a first sealing cover (1), the upper surface of the feeding hole (9) is connected with a second sealing cover (10) in a sliding mode, the inner wall of the second sealing cover (10) is fixedly connected with a sealing plug (12), a first sealing groove (11) is formed in the second sealing cover (10), the outer wall of the feeding hole (9) is connected with the inner wall of the first sealing groove (11) in a sliding mode, and the outer wall of the sealing plug (12) is connected with the inner wall of the feeding hole (9) in a sliding mode.
3. The continuous production reaction vessel for mRNA having a self-cleaning function according to claim 1, wherein: the outer wall fixedly connected with backup pad (15) of cauldron body (14), the lower surface fixedly connected with landing leg (16) of backup pad (15).
4. The continuous production reaction vessel for mRNA having a self-cleaning function according to claim 3, wherein: the lower surface of the kettle body (14) is fixedly connected with a blanking pipe (17), and the inner wall of the blanking pipe (17) is fixedly connected with a first discharging pipe (18).
5. The reaction vessel for continuous production of mRNA having a self-cleaning function according to claim 4, wherein: the inner wall of the blanking pipe (17) is fixedly connected with a second discharging pipe (19), and valves (20) are arranged on the outer walls of the blanking pipe (17) and the first discharging pipe (18).
6. The continuous production reaction vessel for mRNA having a self-cleaning function according to claim 5, wherein: the outer wall fixedly connected with switching valve (21) of second row material pipe (19), the outer wall fixedly connected with of first row material pipe (18) is at the inner wall of switching valve (21), the inner wall sliding connection of switching valve (21) has first piston board (22).
7. The continuous production reaction vessel for mRNA having a self-cleaning function according to claim 6, wherein: the outer wall of the first piston plate (22) is fixedly connected with a connecting rod (23), and one end of the connecting rod (23) is fixedly connected with a second piston plate (24).
8. The continuous production reaction vessel for mRNA having a self-cleaning function according to claim 7, wherein: the outer wall sliding connection of second piston board (24) is at the inner wall of diverter valve (21), the inner wall fixedly connected with bin outlet (25) of diverter valve (21).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202420662685.5U CN222034698U (en) | 2024-04-02 | 2024-04-02 | MRNA continuous production reaction vessel with self-cleaning function |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202420662685.5U CN222034698U (en) | 2024-04-02 | 2024-04-02 | MRNA continuous production reaction vessel with self-cleaning function |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN222034698U true CN222034698U (en) | 2024-11-22 |
Family
ID=93509599
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202420662685.5U Active CN222034698U (en) | 2024-04-02 | 2024-04-02 | MRNA continuous production reaction vessel with self-cleaning function |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN222034698U (en) |
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2024
- 2024-04-02 CN CN202420662685.5U patent/CN222034698U/en active Active
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