CN221945648U - Quantitative sampler convenient to use - Google Patents

Abstract

The utility model provides a quantitative sampler which is convenient to use. This ration sampler includes sample head, siphon and reagent pipe, the sample head includes the dropping liquid mouth in the vertical direction, the liquid outlet, water dropper and accommodation portion, the siphon includes first siphon, the second siphon, gas pocket and rupture portion, the reagent pipe includes body and sealing membrane, first siphon and second siphon are connected through the rupture portion and are located accommodation portion, two kinds of siphon are sealed with the one end of rupture portion junction, the other end is open, be equipped with the gas pocket to keeping away from the siphon upper end of accommodation portion, be equipped with the hole of stepping down on the siphon upper end of approaching accommodation portion, when not needing the adjustment sample volume, can directly use the siphon that has the gas pocket to draw up the sample, when needing the adjustment sample volume, realize the switching use of two kinds of siphons through simple operation rupture portion, and a structure is simple, low cost has solved the inconvenient and the problem that the easy confusion is confused that the multiple sampler of different sample volumes use, convenient for the user use.

Description

Quantitative sampler convenient to use

Technical Field

The utility model relates to a liquid sampler, in particular to a convenient-to-use quantitative sampler with quantitative sampling and quantitative dripping functions.

Background

The disposable micro quantitative sampling and sampling device has wide application in the medical industry at present, along with the continuous development of the medical detection industry, the application of disposable micro quantitative sampling and quantitative sampling is also increasing, two quantitative sampling modes mainly exist in the market at present, one is a siphon type micro quantitative capillary tube with scales, the sampling quantity is controlled by utilizing small holes arranged on an air bag through the siphon principle, the capillary tube is marked with scales, but the sampling precision and the operation method in the operation process are very large, and the accuracy is difficult to achieve. The other is a sampler for micro quantitative sampling and sample adding, although the sampling is very accurate, only one volume of sample can be absorbed, for the same detection project, different sample adding amounts are needed for different samples, and a plurality of samplers are needed to be equipped to meet the requirement of users, so that the product detection cost is increased and the plurality of samplers are easy to cause users to mix and use wrongly.

Therefore, there is an urgent need for a sampler capable of accurately sampling and dripping a plurality of samples, which is convenient for users to accurately sample and drip.

Disclosure of Invention

The application aims to provide a quantitative sampler convenient to use, and aims to solve the problems that the product detection cost is high and a plurality of samplers are easy to cause mismixing and use of users because different samplers need to be replaced when sampling different samples in the same detection project.

A convenient-to-use quantitative sampler, comprising:

The sampling head comprises a liquid drop port, a liquid outlet, a liquid drop head and a containing part;

The siphon comprises a first siphon, a second siphon, air holes and a breaking part;

the reagent tube comprises a tube body and a sealing film;

The first siphon part is located the holding portion, keeps away from the second siphon upper end of holding portion is equipped with the gas pocket, first siphon and second siphon pass through the rupture portion and connect, first siphon, second siphon with the one end that the rupture portion is connected is sealed, and the other end is open, the holding portion is equipped with the hole of stepping down that steps down that is located first siphon. Through hold a siphon of two kinds of specifications that are connected by the rupture portion on a holding portion, be equipped with the gas pocket to the second siphon upper end that keeps away from the holding portion, be equipped with the hole of stepping down near the first siphon upper end of holding portion to realize the switching use of two kinds of specification siphons through simple operation rupture portion, simple structure, the user of being convenient for uses.

Further, the thickness of the breaking part is reduced from the direction away from the accommodating part to the direction approaching the accommodating part, the thickness of the joint of the breaking part and the closed end of the second siphon pipe away from the accommodating part is maximum, and the thickness of the other end of the breaking part is minimum.

Further, the surface with reduced thickness of the breaking part forms an acute angle with the closed end of the first siphon pipe positioned at the accommodating part, and the position with the minimum thickness of the breaking part forms an angle which is easy to break with the connecting position of the closed end of the first siphon pipe close to the accommodating part, so that the breaking part is convenient for a user to operate.

Further, the sampler still includes the block with the sampling head complex, the block internal surface is equipped with the cooperation portion of protrusion internal surface, and the sampling head can make its zonulae occludens and seal through inside and outside screw-thread fit with the block, prevents the pollution that biological reagent drops everywhere after the use.

Further, the matching part is of an annular closed structure, and the inner diameter of the matching part is larger than the outer diameter of the liquid dropping port, or the outer diameter of the matching part is smaller than the inner diameter of the liquid dropping port.

Further, the matching part can accommodate part of the second siphon pipe, and part of the outer edge wall of the matching part can be clamped into part of the break-off part. The matching part arranged on the cap is convenient for a user to clamp the outer edge wall of the matching part into the breaking part, and the breaking part is operated by taking the outer edge wall of the matching part as a contact fulcrum, the siphon pipe at the lower side of the breaking part is removed, and the sample suction port of the siphon pipe at the upper side of the breaking part is leaked.

Further, the thickness of the outer edge wall of the matching part is smaller than the height of the breaking part. The thickness of the outer edge wall of the matching part is smaller, and part of the outer edge wall of the matching part can be clamped into part of the breaking part, so that a user can conveniently match the breaking part with the matching part, and the breaking part is operated by taking the outer edge wall of the matching part as a contact fulcrum.

Further, the dripper comprises a baffle ring, a baffle body and a baffle skirt, wherein the liquid drop port is positioned on the upper side of the baffle ring, the liquid outlet is positioned on the lower side of the baffle body, and the liquid drop port and the liquid outlet are communicated in the vertical direction inside the dripper.

Further, the top end of the accommodating part is connected with the baffle body part and is provided with a liquid outlet, so that the sample buffer liquid smoothly enters from the liquid outlet and drops out from the liquid drop outlet.

Further, the upper end of the cap extends upwards to form a conical cap spike, and the cap spike can puncture the sealing film, so that a user can conveniently place the siphon tube after sucking the sample in the buffer solution of the tube body, and the sample is processed.

Compared with the prior art, the application has the beneficial effects that:

According to the utility model, the two types of siphons connected by the breaking part are placed in one containing part, one end of the joint of the two types of siphons and the breaking part is closed, the other end is open, an air hole is formed at the upper end of the siphon far away from the containing part, a yielding hole is formed at the upper end of the first siphon close to the containing part, when the sampling amount does not need to be adjusted, the siphon with the air hole can be directly used for sucking samples, and the matching part convenient for a user to operate is arranged, so that when the user needs to adjust the sampling amount, the sampling amount of the sampler can be adjusted by simply operating the breaking part, the structure is simple, the cost is low, and the problems of inconvenience and easy confusion caused by using various samplers with different sampling amounts are solved; through the cooperation of the cap and the sampling head, the pollution caused by the dripping of the biological reagent everywhere after the use is prevented; through the arrangement of the spike of the cap, a user can conveniently operate to puncture the sealing film, and the sampled capillary tube is placed in the buffer solution, so that the pretreatment of the sample is realized.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the embodiments will be briefly described below, it being understood that the following drawings only illustrate some embodiments of the present application and therefore should not be considered as limiting the scope of the present application.

FIG. 1 is a schematic view of a sampler according to the present application;

FIG. 2 is a schematic diagram of a closed structure of the sampler according to the present application;

FIG. 3 is a schematic view of a closed cross-section of the sampler of the present application;

FIG. 4 is a schematic diagram of a sampling head according to the present application;

FIG. 5 is a schematic view of a siphon structure according to the present application;

reference numerals:

10-capping; 11-mating part; 12-spike of cap; 20-sampling head; 21-a liquid dropping port; 22-a liquid outlet; 23-drippers; 24-a housing; 241-relief holes; 25-baffle ring; 26-a baffle; 27-a skirt; 30-siphon; 31-a first siphon; 32-a second siphon; 33-air holes; 34-breaking part; 40-reagent tube; 41-tube body; 42-sealing film.

Detailed Description

The following description of the embodiments of the present utility model will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present utility model, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the utility model without making any inventive effort, are intended to be within the scope of the utility model.

The terms "vertical," "upper," "lower," "top," "upper," "lower," "both sides," "first," "second," and the like are used herein for the purpose of illustration only and the term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.

Referring to fig. 1 to 5, the quantitative sampler of the present application includes a cap 10, a sampling head 20, a siphon tube 30 and a reagent tube 40; the upper end of the cap 10 extends upwards to form a cap spike 12, the upper end of the cap 10 can also be in other shapes, the cap spike 12 is provided with a part of tip, and the cap spike 12 can puncture the sealing film 42. The sampling head 20 comprises a liquid drop port 21, a liquid outlet 22, a liquid drop head 23 and a containing part 24 in the vertical direction, the liquid drop head 23 comprises a baffle ring 25, a baffle body 26 and a baffle skirt 27 in the vertical direction, the liquid drop port 21 and the liquid outlet 22 penetrate in the vertical direction in the liquid drop head 23, the liquid drop port 21 is positioned at the upper side of the baffle ring 25, the liquid outlet 22 is positioned at the lower side of the baffle body 26, the top end of the containing part 24 is partially connected with the baffle body 26 and is provided with the liquid outlet 22, so that sample buffer liquid smoothly enters from the liquid outlet 22 and drops from the liquid drop port 21, the containing part 24 is also provided with a yielding hole 241 which is provided with one end of a capillary tube, the specific yielding hole 241 is ventilated with one end opening which is away from the capillary tube sample absorbing port, So that the quantitative sample can be smoothly sucked when the capillary sample sucking port contacts the sample. The siphon tube 30 includes a first siphon tube 31, a second siphon tube 32, an air vent 33 and a breaking part 34, wherein a part of the first siphon tube 31 is positioned at the accommodating part 24, the upper end of the second siphon tube 32 far away from the accommodating part 24 is provided with the air vent 33, the first siphon tube 31 and the second siphon tube 32 are connected through the breaking part 34, the air vent is positioned on the second siphon tube 32 at the lower side of the breaking part 34, the breaking part 34 can be broken by external force, the second siphon tube 32 at the lower side of the breaking part 34 is removed, so that a user can use the first siphon tube 31 at the upper side, and when the breaking part 34 is not operated by external force, the user can directly use the second siphon tube 32 with the air vent at the lower side of the breaking part 34, the siphon tube may be a capillary tube, and the first siphon tube and the second siphon tube are for illustration purposes only, and not particularly limited, and for clarity of description, the embodiment will be a first siphon tube 31 located on the upper side of the break portion 34, and will be a second siphon tube 32 located on the lower side of the break portion 34, and of course, the second siphon tube 32 may also be located on the upper side of the break portion 34, and the first siphon tube 31 may also be located on the lower side of the break portion 34; Preferably, when the inner diameters of the first siphon tube 31 and the second siphon tube 32 are the same, the siphon volume is large and is positioned on the upper side of the breaking part 34, and when the inner diameters of the first siphon tube 31 and the second siphon tube 32 are different, the inner diameter is large and is positioned on the upper side of the breaking part 34, the inner diameter is small and is positioned on the lower side of the breaking part 34, so that a user can conveniently operate the breaking part 34 with smaller force, remove the siphon pipe positioned on the lower side of the breaking part 34, the siphon pipe can be manufactured by adopting the processes of injection molding process, mold process and the like, and the siphon pipe can be made of glass, PVC, PP, PE and the like. Specifically, when the detection item is CRP, the first siphon 31 and the second siphon 32 have the same inner diameter, the first siphon 31 is a 10 ul siphon, and the second siphon 32 is a 5ul siphon; When the inner diameters of the first siphon tube 31 and the second siphon tube 32 are different, the first siphon tube 31 is a 10 ul siphon tube with a larger inner diameter, and the second siphon tube 32 is a 5ul siphon tube with a smaller inner diameter. When the user uses serum or plasma, the second siphon tube 32 is directly used for sucking the sample and then the subsequent operation is performed; when the user uses whole blood, the user operates the breaking part 34, removes the second siphon tube 32, sucks the sample using the first siphon tube 31, and performs the subsequent operation. The reagent tube 40 includes a tube body 41 and a sealing film 42, the tube body 41 containing a reaction solution, and the upper end of the tube body 41 being sealed by the sealing film 42.

The inner surface of the upper end of the tube body 41 is provided with an annular groove, the outer surface of the baffle 26 is provided with an annular bulge, and the baffle 26 and the reagent tube 40 are matched through the annular groove and the annular bulge, so that the sampling head 20 can be well sealed after entering the reagent tube 40, or the inner surface of the upper end of the tube body 41 can be provided with the annular bulge, and the outer surface of the baffle 26 is provided with the annular groove or other tightly matched modes such as internal threads, external threads and the like, and the invention is not limited in particular; the baffle ring 25 is provided with external threads, the inner surface of the cap 10 is provided with internal threads, the cap 10 and the sampling head 20 can be tightly connected and sealed through the matching of the internal threads and the external threads after the cap is in an initial state or used, pollution caused by the dripping of biological reagents everywhere after the cap is used is prevented, the matching mode of the cap 10 and the baffle ring 25 is not limited to the matching connection of the internal threads and the external threads or the pressing connection, and the specific mode is not limited; for better controlling the position of the sampling head 20 entering the reagent tube 40, the skirt 27 arranged at the upper end of the sampling head 20 can prevent the sampling head 20 from being in interference fit with the reagent tube 40, and of course, the skirt 27 can also be arranged at the upper side of the reagent tube 40, and the arrangement of the skirt on one side of the sampling head 20 or the reagent tube 40 or the skirt on both sides of the sampling head 20 and the reagent tube 40 can prevent the sampling head 20 from being in interference fit with the reagent tube 40.

The inner surface of the cap 10 is provided with a protruding mating portion 11, and the mating portion 11 is preferably a protruding annular sealing structure, but may also be a protruding non-annular sealing structure or a non-sealing sheet structure. When the fitting portion 11 is a raised annular sealing structure or a non-annular sealing structure, the inner diameter of the fitting portion is preferably larger than the outer diameter of the drip opening 21, so that when the cap 10 is fitted with the baffle ring 25 of the sampling head 20, the drip opening 21 enters the fitting portion 11, a certain space can be saved to accommodate the fitting portion 11 and the drip opening 21, or the outer diameter of the fitting portion 11 is smaller than the inner diameter of the drip opening 21, so that when the cap 10 is fitted with the baffle ring 25 of the sampling head 20, the fitting portion 11 enters the drip opening 21, and a certain space can be saved to accommodate the fitting portion 11 and the drip opening 21; when the fitting portion 11 is of a convex non-closed sheet structure and the cap 10 is fitted with the baffle ring 25, the fitting portion 11 can be partially positioned in the drip opening 21 or outside the drip opening 21, and is staggered from the drip opening 21, so that a certain space is saved for accommodating the fitting portion 11 and the drip opening 21.

When the matching portion 11 is a raised annular closed structure or a non-annular closed structure, the siphon pipe positioned at the lower side of the breaking portion 34 can be inserted into the closed structure, so that the breaking portion 34 contacts with the outer edge wall of the closed structure, and part of the outer edge wall of the closed structure is clamped into part of the breaking portion 34, preferably, part of the outer edge wall of the closed structure is clamped into the part of the smaller thickness of the breaking portion 34, namely, the angle formed by the breaking portion 34 and the siphon pipe; when the matching portion 11 is in a non-closed sheet structure, the breaking portion 34 can be close to the non-closed sheet structure, so that the breaking portion (34) is in contact with the outer edge wall of the non-closed sheet structure, and part of the outer edge wall of the non-closed structure is clamped into part of the breaking portion 34, preferably, part of the outer edge wall of the non-closed structure is clamped into a part of the breaking portion 34, which is smaller in thickness, namely, the angle formed by the breaking portion 34 and the siphon tube; the thickness of the outer edge wall of the mating portion 11 is smaller than the height of the breaking portion 34, specifically, is smaller than or equal to the height h of the breaking portion 34, and the height of the breaking portion 34 is shown in fig. 5. The outer edge wall refers to the uppermost position of the mating part formed on the inner surface of the protruding cap 10, and the snap-in means that the outer edge wall of the mating part 11 can be partially placed into the breaking part 34; the thickness of the wall of the breaking part 34 decreases along the direction h from the direction away from the accommodating part to the direction approaching the accommodating part, the thickness of one end of the breaking part 34 connected with the sample suction opening of the first siphon tube 31 is minimum, the thickness of the other end is maximum, the surface of the reduced thickness of the breaking part forms an acute angle with one closed end of the first siphon tube positioned at the accommodating part, the acute angle is easier to break, when the breaking part 34 contacts with the outer edge wall of the matching part 11, the thickness of the outer edge wall of the matching part 11 is preferably smaller than the height h of the breaking part 34, and a user can operate the breaking part 34 with minimum force to remove the second siphon tube 32 positioned at the lower side of the breaking part 34. Of course, the cap 10 may not be provided with the engaging portion 11, and the user may operate the breaking portion 34 or directly break the breaking portion 34 by other means.

The specific use mode is as follows:

When the detection item is CRP (C-reactive protein), the first siphon 31 is located above the break 34, the second siphon 32 is located below the break 34, the first siphon 31 is a 10ul siphon, and the second siphon 32 is a 5ul siphon.

When the sample is plasma or serum:

A. reversing the cap 10 and puncturing the sealing film 42 with the cap spike 12;

B. Aligning the second siphon 32 with the plasma or serum, and aspirating a quantitative sample;

C. Extending the second siphon tube 32 with the absorbed plasma or serum into the buffer solution of the reagent tube 40, simultaneously extending the sampling head 20 into the reagent tube 40 and compacting, and shaking the sampler to mix the plasma or serum with the buffer solution uniformly;

D. The cap 10 was unscrewed, the drop port 21 was aligned with the test strip, two drops (about 100 uL) of buffer sample were dropped into the strip port, and the result was read in 5 minutes while waiting for the occurrence of a red line.

When the sample is whole blood:

① The cap 10 is unscrewed, the breaking part 34 is aligned to the outer edge wall part of the matching part 11, a certain force is applied by taking the contact part of the breaking part 34 and the outer edge wall of the matching part 11 as a fulcrum, and simultaneously the second siphon tube 32 is contacted with the inner wall of the cap 10, so that the breaking part 34 is broken, and the second siphon tube 32 is removed;

② Tightening the cap 10 and the sampling head 20, aligning the first siphon tube 31 with the whole blood, and sucking a quantitative sample;

③ The first siphon tube 31 with the whole blood absorbed therein is stretched into the buffer solution of the reagent tube 40, meanwhile, the sampling head 20 is stretched into the reagent tube 40 and is tightly pressed, and the sampler is shaken, so that the plasma or serum is uniformly mixed with the buffer solution;

④ The cap 10 was unscrewed, the drop port 21 was aligned with the test strip, two drops (about 100 uL) of buffer sample were dropped into the strip port, and the result was read in 5 minutes while waiting for the occurrence of a red line.

Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present application, and not for limiting the same; although the application has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit of the application.

Furthermore, those skilled in the art will appreciate that while some embodiments herein include some features but not others included in other embodiments, combinations of features of different embodiments are meant to be within the scope of the application and form different embodiments. For example, in the claims below, any of the claimed embodiments may be used in any combination. The information disclosed in this background section is only for enhancement of understanding of the general background of the application and should not be taken as an acknowledgement or any form of suggestion that this information forms the prior art already known to a person skilled in the art.

Claims (10)

1. A quantitative sampler that is easy to use, characterized in that it includes: A sampling head (20), the sampling head (20) comprising a liquid dripping port (21), a liquid outlet (22), a dripper (23) and a containing portion (24); A siphon tube (30), the siphon tube (30) comprising a first siphon tube (31), a second siphon tube (32), an air hole (33) and a broken portion (34); A reagent tube (40), the reagent tube (40) comprising a tube body (41) and a sealing film (42); The first siphon tube (31) is partially located in the accommodating portion (24), and an air hole (33) is provided at the upper end of the second siphon tube (32) away from the accommodating portion (24). The first siphon tube (31) and the second siphon tube (32) are connected via a breaking portion (34), and one end of the first siphon tube (31) and the second siphon tube (32) connected to the breaking portion (34) is closed, while the other end is open, and the accommodating portion (24) is provided with a making way hole (241) for making way for the first siphon tube (31). 2. The easy-to-use quantitative sampler according to claim 1, characterized in that the thickness of the breaking portion (34) decreases from away from the accommodating portion (24) to close to the accommodating portion (24). 3. The easy-to-use quantitative sampler according to claim 2, characterized in that the surface of the broken portion (34) with reduced thickness forms an acute angle with the closed end of the first siphon tube (31) partially located in the accommodating portion (24). 4. The easy-to-use quantitative sampler according to claim 1, characterized in that it also includes a cap (10) that matches the sampling head (20), and the inner surface of the cap (10) is provided with a matching portion (11) that protrudes from the inner surface. 5. The easy-to-use quantitative sampler according to claim 4 is characterized in that the matching portion (11) is an annular closed structure, the inner diameter of the matching portion (11) is larger than the outer diameter of the dripping port (21), or the outer diameter of the matching portion (11) is smaller than the inner diameter of the dripping port (21). 6. The easy-to-use quantitative sampler according to claim 4, characterized in that the matching portion (11) can accommodate a portion of the second siphon (32) away from the accommodating portion (24), so that a portion of the outer edge wall of the matching portion (11) can be stuck in a portion of the broken portion (34). 7. The easy-to-use quantitative sampler according to claim 4 or 6, characterized in that the thickness of the outer edge wall of the matching portion (11) is smaller than the height of the breaking portion (34). 8. The easy-to-use quantitative sampler according to claim 1 is characterized in that the dripper (23) includes a retaining ring (25), a retaining body (26) and a retaining skirt (27), the dripping port (21) is located on the upper side of the retaining ring (25), the liquid outlet (22) is located on the lower side of the retaining body (26), and the dripping port (21) and the liquid outlet (22) are connected in the vertical direction inside the dripper. 9. The easy-to-use quantitative sampler according to claim 8, characterized in that the top end of the accommodating portion (24) is partially connected to the blocking body (26) and makes way for the liquid outlet (22). 10. The easy-to-use quantitative sampler according to claim 4, characterized in that the upper end of the cap (10) extends upward to form a conical cap spike (12), and the cap spike (12) can pierce the sealing film (42).